Pott\'s Puffy Tumour: A Case Report

A 10-year-old girl presented with an episode of seizure following osteomyelitis of the frontal bone and subperiosteal abscess due to frontal sinusitis. CT scan confirmed osteomeyelitis of the frontal bone and subperiosteal abscess. At surgery, the subperiosteal abscess and contiguous subdural abscess was drained and sequestrectomy of the affected frontal bone done. Broad spectrum antibiotics and anticonvulsant were given for 4 weeks. The patient recovered without residual problems and has remained well at 5 years of follow up. Pott\'s puffy tumor is now relatively uncommon and associated seizure is unusual. Early diagnosis and prompt treatment is necessary to avoid severe neurological complications and sequelae. Keywords: Pott\'s puffy tumour, frontal sinusitis, seizure Annals of African Medicine Vol. 7 (3) 2008: pp. 138-14

Neurosurgical infections

The central nervous system is a very delicate and vulnerable organ which enjoys protection by layers of coverings. It is described as an immunological vacuum, and when afflicted by infections the outcome ismost often devastating. Factors leading to compromise of the host defense play a major role in establishing neurosurgical infections. A number of such factors can either be avoided or minimized. Over the past decades, these infections have been fatal. However, more recently, the advent of newermore effective antibiotics, improved bacteriological studies, advanced imaging facilities, and meticulous surgical techniques have turned around the outcomes. This article will review infections of the central nervous system of neurosurgical significance

Images in Clinical Practice: Pituitary Macroadenoma

No Abstract Available Annals of African Medicine Vol.3(2) 2004: 93-9

Posterior Surgical Approach to Tuberculous Spondylitis

Objectives: Foraminotomy is a simple posterior surgical approach useful for treatment of radicular (nerve root) pain in TB spondylitis. It doesn't affect the stability of the facet joint, requires neither fusion nor implants. It is therefore cheap and affordable for patients with low income. We describe a simple form of posterior spinal surgery for patients with tuberculous spondylitis. Methods: Out of the 45 cases of Pott's disease managed from Jan 2006-Jan 2008, three patients had foraminotomy due to failed medical treatment. An additional discectomy was performed in one patient. Foraminotomy involves the removal of lateral half of adjacent laminae and medical half of the facet joint. The ligamentum flavum and the epidural fat are cleared to free the nerve root. No implant or fusion is required. Results: All the three patients improved post operatively. Physiotherapy was started on 7th day after surgery. The pain completely resolved in two patients while the third one had a remarkable improvement at discharge. They were all able to walk without support. One patient is still on regular follow up and has a power of 5/5 in both lower limbs while the remaining two were lost to follow up at 5 and 8 months post surgery. They both had power of 4/5 at the time they defaulted. Conclusion: Foraminotomy with or without discectomy is a simple posterior surgical approach to T B spine with good neurological outcome. It is adapted to our environment because no fusion or implant is required. Key words: Tuberculosis, Spondylitis, Posterior approac

Bioassay guided isolation of active phytochemicals from hyphaenethebaica (L) mart fruit pulp methanol extract responsible for hypoglycaemic activity

Active phytochemical responsible for hypoglycaemicactivily from Hyphaenethebaica (L) Mart were separated using Bioassay guided fractionation. Methodology: Five hundred grams (500g) methanolic fruit extract of H. thebaicawas suspended in water, filtered and sequentially partitioned with hexane, chloroform, ethyl acetate and n-butanol. The n-butanol fraction was subjected to column chromatography, sub-fraction A, B, C, D, E, F and G were obtained. Further separation using preparative TLC of fraction C afforded sub-fraction C, C, and 1 2 C. Finally, C gaveRF value. Diabetes was induced to albino rats of both sexes by intra muscular 3 1 injection of 120mg/kg Alloxan monohydrate. The diabetic rats were grouped according to the number of fractions and sub-fractions with 3 rats each. Each fraction was tested for hypoglycaemic activity. The one with highest activity was used for next study and phytochemical constituents analysed. Results: The phytochemical screening of70% methanol extract of Hyphaenethebaicafruit pulp were reported to contain saponins, tannins, terpenoids, cardiac glycosides with the exception of alkaloid, combined anthraquinone, free anthraquinone and soluble starch. The n-butanol portion showed hypoglycaemic activity (66.37±1.03% reduction) compared to other fractions at 400mg/kg. The n-butanol portion similarly contained phytochemicals found in crude extract except forsaponins which is absent. The column fraction C of the n-butanol portion has maximum reduction (45.33± 2.80%) of fasting blood glucose of diabetic rats at a lower dose of 200 mg/kg. Sub-fraction C has more hypoglycaemic activity of 1 60.50%while phytochemical evaluation showed the presence of flavonoids. Conclusion: Flavonoids may be responsible for the observed hypoglyceamic effect of H. thebaicsfruit pulp

Primary Central Nervous System Burkitt Lymphoma With Non-Immunoglobulin Heavy Chain Translocation in Right Ventricle: Case Report

Primary central nervous system Burkitt lymphoma (PCNSBL) is rare. Few cases of primary central nervous system involvement with sporadic Burkitt lymphoma have been reported and its treatment is now controversial. Here, the authors report a case of a 14-year-old boy suffering from non-immunoglobulin heavy chain (IgH) translocation PCNSBL. To the authors' knowledge, this is the second case report describing primary Burkitt lymphoma involving cerebral ventricles. After receiving combination treatment with surgery, stereotacticradiosurgery, and a chemotherapy regimen including high-dose methotrexate, the patient had a disease-free survival of 18 months

Search for direct pair production of the top squark in all-hadronic final states in proton-proton collisions at s√=8 TeV with the ATLAS detector

The results of a search for direct pair production of the scalar partner to the top quark using an integrated luminosity of 20.1fb−1 of proton–proton collision data at √s = 8 TeV recorded with the ATLAS detector at the LHC are reported. The top squark is assumed to decay via t˜→tχ˜01 or t˜→ bχ˜±1 →bW(∗)χ˜01 , where χ˜01 (χ˜±1 ) denotes the lightest neutralino (chargino) in supersymmetric models. The search targets a fully-hadronic final state in events with four or more jets and large missing transverse momentum. No significant excess over the Standard Model background prediction is observed, and exclusion limits are reported in terms of the top squark and neutralino masses and as a function of the branching fraction of t˜ → tχ˜01 . For a branching fraction of 100%, top squark masses in the range 270–645 GeV are excluded for χ˜01 masses below 30 GeV. For a branching fraction of 50% to either t˜ → tχ˜01 or t˜ → bχ˜±1 , and assuming the χ˜±1 mass to be twice the χ˜01 mass, top squark masses in the range 250–550 GeV are excluded for χ˜01 masses below 60 GeV

Search for pair-produced long-lived neutral particles decaying to jets in the ATLAS hadronic calorimeter in ppcollisions at √s=8TeV

The ATLAS detector at the Large Hadron Collider at CERN is used to search for the decay of a scalar boson to a pair of long-lived particles, neutral under the Standard Model gauge group, in 20.3fb−1of data collected in proton–proton collisions at √s=8TeV. This search is sensitive to long-lived particles that decay to Standard Model particles producing jets at the outer edge of the ATLAS electromagnetic calorimeter or inside the hadronic calorimeter. No significant excess of events is observed. Limits are reported on the product of the scalar boson production cross section times branching ratio into long-lived neutral particles as a function of the proper lifetime of the particles. Limits are reported for boson masses from 100 GeVto 900 GeV, and a long-lived neutral particle mass from 10 GeVto 150 GeV

Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at root s = 8 TeV with the ATLAS detector (vol 75, 299, 2015)

Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √s=8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT>120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between EmissT>150 GeV and EmissT>700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presented