12 research outputs found
Controlled growth of organic semiconductor films in liquid
- Publication venue
- Western CEDAR
- Publication date
- 01/01/2011
- Field of study
Organic molecular crystalline (OMC) films are being investigated for use in a wide range of potential applications, from field effect transistors, to light-emitting diodes, and photovoltaic cells. The ultimate utility of OMC materials for such applications will depend on the degree and type of molecular order in deposited films, as well as the processing costs for preparing them. The goal of this thesis is to develop a method to produce high quality OMC thin films under ambient conditions, to characterize those films, and their growth kinetics. In particular, I will investigate OMC film growth by ambient axisymmetric spray method, a technique in which an organic semiconductor is sublimated into a carrier gas at ambient pressure and deposited onto a substrate coated with a thin liquid layer. I will examine the growth kinetics and morphologies of the resulting films. The results of this research will be an improved understanding of the growth of organic crystals in a thin film of liquid and the production of cheap organic semiconductor thin films
Organic-Vapor-Liquid-Solid Deposition with an Impinging Gas Jet
- Author
- Publication venue
- Western CEDAR
- Publication date
- 01/04/2012
- Field of study
A method for rapid, mass-efficient deposition of highly crystalline organic films under near ambient conditions of pressure and temperature is reported based on delivery of an organic precursor via an impinging gas jet to a substrate coated by a thin liquid solvent layer. Films of the organic semiconductor tetracene were deposited by sublimation into a flow of argon carrier gas directed at an indium-tin-oxide/glass substrate coated by a thin layer of bis(2-ethylhexyl)sebecate, and growth was followed in situ with optical microscopy. A fluid dynamics model is applied to account for the gas phase transport and aggregation, and the results compared to experiment. The combination of gas jet delivery with an organic-vapor-liquid-solid growth mechanism leads to larger crystals and lower nucleation densities than on bare surfaces, with markedly different nucleation and growth kinetics. An explanation based on enhanced solution-phase diffusivity and a larger critical nucleus size in the liquid layer is proposed to account for the differences
Chromophores in operative surgery: Current practice and rationalized development
- Author
- Alexander
- Ali
- Andreas
- Barrows
- Barthelmes
- Bonkovsky
- Breidablik
- Burgoyne
- Cardillo
- Chen
- Christmas
- Chung
- Commission E
- Culjat
- Daniel Rees
- de Boer
- de Lima
- De Veld
- Drinkwater
- Eileen Kairuz
- Engel
- Eren
- Ernest A. Azzopardi
- Fabian
- Fedorow
- Franklin
- Gousse
- Griffiths
- Gurtner
- Hanash
- Hendry
- Hunger
- Iain S. Whitaker
- Jacobs
- Jeon
- Johansson
- Keereweer
- Khan
- Kiernan
- Kiernan
- Kim
- Koivusalo
- Krafts
- Levitus
- Lewis W. Francis
- Lindo
- Liu
- Lucová
- M. Anne Sawhney
- Manson
- Marc Clement
- Masannat
- Matsumura
- Mauerer
- Maxwell Murison
- McLeod
- Moore
- Morton
- Mosyagin
- Naitoh
- Nakamura
- Nioka
- Nürnberg
- R. Sofia Rodrigues Teixeira
- R. Steven Conlan
- Rashid
- Sabnis
- Samorani
- Shaw
- Shir
- Siân-Eleri Owens
- Slominski
- Sondak
- Stolz
- Stradling
- Sturmey
- Telgenkamp
- Vuylsteke
- Wainwright
- Yuen
- Zhou
- Publication venue
- 'Elsevier BV'
- Publication date
- 23/01/2017
- Field of study
BackgroundChromophore-containing molecules feature extensively in surgical practice, with synthetic dyes gaining popularity over endogenous optical adjuncts. New applications for chromophores in diagnostics and operative treatment exploit unique chemical structures suited for illuminating target tissues beyond the visual spectrum, ranging from ultraviolet (UV) to near-infrared (NIR). This review outlines the rationale for surgical chromophore application, the weaknesses and risks in each class of these compounds, and areas of foreseeable potential for employment of specialized contrast agents.MethodAn English-language literature search applied the following Boolean Search String: “dye OR Lake OR Stain OR chromophore” AND “toxORterato∗ORcarcino OR AllergORsurg OR clinic” using EMBASE, PUBMED, PUBMED central and OVIDSp, with back-referencing through Web of Knowledge™.ResultsBased on the primary literature, this study proposes a surgically relevant classification system of chromophores in current use, which facilitates risk/benefit consideration for the surgeon who employs them, and which facilitates clinically oriented development.ConclusionsThe next stage of development for optically active surgical adjuncts must address practical constraints whilst minimizing risks of adverse effects. Exploiting the technology's full potential also requires improvements in the usefulness of imagery equipment
New genetic loci link adipose and insulin biology to body fat distribution.
- Author
- Aalto Ville
- Aasarød Knut
- Abecasis Goncalo R
- Abecasis Gonçalo
- Absher Devin
- Adair Linda S
- Adam Martin
- Adeyemo Adebowale
- Ahlqvist Emma
- Ahmadi Kourosh R
- Ahola Aila
- Ainali Chrysanthi
- Akylbekova Ermeg
- Ala-Korpela Mika
- Alavere Helen
- Albagha Omar M E
- Albrecht Eva
- Alen Markku
- Alexander Myriam
- Alhenc-Gelas François
- Alizadeh Behrooz Z
- Allison Matthew A
- Alonso Nerea
- Altshuler David
- Ambite Jose Luis
- Amin Najaf
- Amouyel Philippe
- An Ping
- Anderson Carl A
- Anderson Denise
- Anderson Garnet
- Andrews Jeanette S
- Antonella Mulas
- Antti Jula
- Aragaki Aaron K
- Arking Dan E
- Arnold Alice
- Arnold Alice M
- Arora Pankaj
- Arscott Gillian M
- Artigas Maria Soler
- Arveiler Dominique
- Asiki Gershim
- Aspelund Thor
- Assimes Themistocles L
- Atalay Mustafa
- Atkinson Elizabeth J
- Aulchenko Yurii
- Avery Christy
- Bain Stephen C
- Bakker Stephan J L
- Balcells Susana
- Balkau Beverley
- Ballantyne Christie M
- Balmforth Anthony J
- Bandinelli Stefania
- Barbalic Maja
- Barrett Amy
- Barroso Ines
- Barroso Inês
- Basart Hanneke
- Basart Hanneke V
- Bataille Veronique
- Baumert Jens
- Beckmann Jacques S
- Beekman Marian
- Been Latonya F
- Beilby John
- Beilby John P
- Bell Jordana T
- Bellis Claire
- Bennett Amanda J
- Bennett Franklyn
- Berenson Gerald S
- Bergman Richard N
- Bergmann Sven
- Berndt Sonja I
- Berne Christian
- Bidulescu Aurelian
- Bielak Lawrence F
- Bierut Laura J
- Biffar Reiner
- Bis Joshua C
- Blackburn Hannah
- Blangero John
- Blankenberg Stefan S
- Blüher Matthias
- Boban Mladen
- Bochud Murielle
- Boehm Bernhard O
- Boehnke Michael
- Boerwinkle Eric
- Boezen H Marike
- Bolton Jennifer L
- Bolton Judith A Hoffman
- Bonnet Fabrice
- Bonnycastle Lori L
- Boomsma Dorret I
- Borecki Ingrid
- Boright Andrew P
- Borja Judith B
- Bornstein Stefan R
- Boston Jonathan
- Bots Michiel L
- Bouatia-Naji Nabila
- Bouchard Claude
- Bovet Pascal
- Boyd Heather A
- Bragg-Gresham Jennifer L
- Brambilla Paolo
- Brand Eva
- Brand Stefan-Martin
- Brandi Maria Luisa
- Braund Peter S
- Brennan Eoin P
- Brismar Kerstin
- Brody Jennifer
- Broekmans Frank J
- Broer Linda
- Brown Matthew A
- Brown Morris J
- Brown-Gentry Kristin
- Bruinenberg Marcel
- Buchkovich Martin L
- Buckley Brendan M
- Buil Alfonso
- Bull Shelley B
- Burgdorf Christof
- Buring Julie E
- Burnett Mary S
- Burnier Michel
- Burri Andrea
- Burton Paul R
- Bush William S
- Busonero Fabio
- Buxbaum Sarah G
- Buyske Steve
- Buzkova Petra
- Byrne Enda M
- Böger Carsten A
- Böhringer Stefan
- Böttcher Yvonne
- Cambien Francois
- Campbell Harry
- Campbell Susan
- Carba Delia B
- Carlson Chris
- Carlson Olga D
- Carty Cara
- Casas Juan P
- Caspersen Ida H
- Castano-Betancourt Martha
- Cauchi Stéphane
- Cauley Jane A
- Caulfield Mark
- Cavalieri Margherita
- Cazier Jean-Baptiste
- Center Jacqueline R
- Cesana Giancarlo
- Chakravarti Aravinda
- Chambers John
- Chandak Giriraj R
- Chang Hsing-Yi
- Chang Yen-Pei C
- Chanock Stephen J
- Charchar Fadi J
- Chasman Dan
- Chaturvedi Nish
- Chen Constance
- Chen Han
- Chen Ida
- Chen Jin
- Chen Ming-Huei
- Chen Wei
- Chen Yii-Der Ida
- Cheng Iona
- Cheng Sulin
- Chines Peter S
- Cho Yoon Shin
- Choi Murim
- Chouraki Vincent
- Christiansen Claus
- Chu Audrey Y
- Cimponeriu Dan
- Ciullo Marina
- Clark Graeme R
- Clarke Robert
- Claudi-Boehm Simone
- Coassin Stefan
- Cochran Barbara
- Cole Shelley
- Colhoun Helen
- Colhoun Helen M
- Collins Francis S
- Collins Rory
- Connell John M
- Cooper Cyrus
- Cooper Jackie A
- Cooper Matthew N
- Cooper Richard S
- Coresh Josef
- Cornelis Marilyn C
- Corre Tanguy
- Corsi Anna Maria
- Couper David
- Cousminer Diana L
- Coviello Andrea D
- Cox David
- Crawford Dana
- Crisponi Laura
- Croteau-Chonka Damien C
- Cucca Francesco
- Cummings Steven R
- Cupples Adrienne L
- Cupples L Adrienne
- Curhan Gary
- d'Adamo Pio
- Dahgam Santosh
- Dailiana Zoe
- Danesh John
- Danoy Patrick
- Dastani Zari
- Davies Gail
- Daw E Warwick
- Day Felix R
- Day Ian N M
- de Andrade Mariza
- de Boer Ian H
- de Boer Rudolf A
- de Faire Ulf
- de Geus Eco J C
- Deary Ian J
- Dedoussis George
- Dedoussis George V
- Dedoussis George V Z
- Deelen Joris
- Deelman Ewa
- Dehghan Abbas
- Delgado Graciela
- Deloukas Panagiotis
- Deloukas Panos
- Demerath Ellen W
- Demirkan Ayse
- Demirkan Ayşe
- Den Hertog Heleen M
- Denniff Matthew
- Dennison Elaine M
- Dermitzakis Emmanouil T
- Deshmukh Harshal
- Deshmukh Harshal A
- Devuyst Olivier
- di Meglio Paola
- Diemert Patrick
- Dimas Antigone S
- Dimitriou Maria
- Ding Jingzhong
- Do Ron
- Dominiczak Anna F
- Doney Alex
- Dong Yanbin
- Donnelly Louise A
- Doumatey Ayo
- Dreisbach Albert W
- Drong Alexander W
- Duggan David
- Dumitrescu Logan
- Duncan Bruce B
- Duncan Emma L
- Dupuis Josee
- Dupuis Josée
- Durbin Richard
- Durda Peter
- Döring Angela
- Dörr Marcus
- Eastell Richard
- Easton Douglas F
- Ebrahim Shah
- Econs Michael J
- Edkins Sarah
- Egan Josephine
- Ehret Georg
- Eiriksdottir Gudny
- Eisman John A
- Eklund Niina
- El Mokhtari NourEddine
- Elks Cathy E
- Ellinghaus David
- Elliott Paul
- Elosua Roberto
- Emilsson Valur
- Endlich Karlhans
- Epstein Stephen E
- Erbel Raimund
- Erdmann Jeanette
- Erdos Michael R
- Eriksson Joel
- Eriksson Johan
- Eriksson Niclas
- Eriksson Per
- Ernst Florian
- Esko Tonu
- Esko Tõnu
- Esko Tönu
- Estrada Karol
- Eury Elodie
- Evangelou Evangelos
- Evans Alun
- Evans David M
- Eyheramendy Susana
- Eyjolfsson Gudmundur Ingi
- Fagerholm Emma
- Falhammar Henrik
- Fall Tove
- Farrall Martin
- Fauser Bart C J M
- Fava Cristiano
- Feenstra Bjarke
- Fehrmann Rudolf
- Feitosa Mary
- Feranil Alan B
- Ferrannini Ele
- Ferrario Marco M
- Ferreira Teresa
- Ferreli Liana
- Ferrières Jean
- Ferrucci Luigi
- Fischer Krista
- Florez Jose C
- Folkersen Lasse
- Folsom Aaron R
- Fontanillas Pierre
- Ford Ian
- Fornage Myriam
- Foroud Tatiana
- Forouhi Nita G
- Forrester Terrence
- Forsblom Carol
- Foster Meredith C
- Fowke Jay
- Fowkes F Gerald R
- Fowkes Gerard R
- Fox Caroline S
- Fox Ervin R
- Franceschini Nora
- Franco Oscar H
- Franco-Cereceda Anders
- Franke Andre
- Franke Lude
- Franks Paul W
- Frants Rune
- Fraser Ross M
- Frayling Timothy M
- Freedman Barry I
- Freimer Nelson B
- Freitag Daniel F
- Friedrich Nele
- Froguel Philippe
- Frost Morten
- Fuchsberger Christian
- Galan Pilar
- Ganesh Santhi K
- Ganna Andrea
- Gansevoort Ron T
- Gao Xiaoyi
- Garcia Melissa
- Garcia-Giralt Natàlia
- Garnaas Maija
- Gasparini Paolo
- Gauguier Dominique
- Gaunt Tom R
- Gautvik Kaare M
- Geller Frank
- Gharavi Ali G
- Giedraitis Vilmantas
- Gieger Christian
- Gierman Hinco J
- Gigante Bruna
- Gill Geoffrey V
- Giroux Sylvie
- Giulianini Franco
- Glass Daniel
- Glazer Nicole
- Glazer Nicole L
- Glenn Kim
- Glorioso Nicola
- Go Alan S
- Go Min Jin
- Godson Catherine
- Goel Anuj
- Goessling Wolfram
- Golay Alain
- Goldstein Benjamin A
- Goltzman David
- Gong Jian
- González-Macías Jesús
- Goodall Alison H
- Goodarzi Mark O
- Goodloe Robert
- Gordin Daniel
- Gordon Scott D
- Gorski Mathias
- Grabe Hans-Jörgen
- Graff Misa
- Grallert Harald
- Grammer Tanja B
- Gravito Martha L
- Greenwood Celia M T
- Grewal Jagvir
- Grimsby Jonna
- Grobbee Diederick E
- Groop Leif
- Groop Per-Henrik
- Gross Myron
- Groves Christopher J
- Grundberg Elin
- Grässler Jürgen
- Gräßler Jürgen
- Gu Harvest F
- Gu Tianwei
- Guarrera Simonetta
- Gudbjartsson Daniel F
- Gudnason Villi
- Gudnason Vilmundur
- Guiducci Candace
- Guo Qun
- Guo Xiuqing
- Gurdasani Deepti
- Gustafsson Stefan
- Gyllensten Ulf
- Gyllensten Ulf B
- Hadjadj Samy
- Hadley David
- Haessler Jeff
- Hager Jörg
- Haiman Christopher
- Haines Jonathan
- Hall Alistair S
- Hall Per
- Hallan Stein
- Haller Toomas
- Hallmans Goran
- Hallmans Göran
- Hamsten Anders
- Han Bok-Ghee
- Hankinson Susan E
- Hanson Robert L
- Hardy Rebecca
- Haritunians Talin
- Harjutsalo Valma
- Harris Tamara
- Hartikainen Anna-Liisa
- Hartman Catharina A
- Hass Merli
- Hassanali Neelam
- Hassinen Maija
- Hastie Nicholas D
- Hastie Nick
- Hattersley Andrew T
- Haun Margot
- Havulinna Aki S
- Hayward Caroline
- Hazen Stanley L
- He Bing
- He Chunyan
- Heard-Costa Nancy L
- Heath Andrew C
- Heath Simon
- Heckbert Susan R
- Hedblad Bo
- Hedman Åsa K
- Heid Iris M
- Heikkilä Kauko
- Heikkilä Outi
- Heiss Gerardo
- Heliövaara Markku
- Helmer Catherine
- Helmer Quinta
- Henders Anjali K
- Henderson Brian
- Hengstenberg Christian
- Henneman Peter
- Hercberg Serge
- Herder Christian
- Hernandez Dena
- Hernandez Dena G
- Herrera Lizbeth
- Herzig Karl-Heinz
- Hicks Andrew A
- Hietala Kustaa
- Higashio Julia
- Hillege Hans L
- Hilton Gina
- Hindorff Lucia
- Hingorani Aroon
- Hirschhorn Joel N
- Hivert Marie-France
- Ho Weang K
- Hocking Lynne J
- Hoffmann Wolfgang
- Hofman Albert
- Holliday Elizabeth G
- Holm Hilma
- Holmen Oddgeir
- Homuth Georg
- Hopewell Jemma C
- Horikoshi Momoko
- Hosseini Mohsen
- Hottenga Jouke-Jan
- Hovingh G Kees
- Howard Philip
- Hsiung Chao Agnes
- Hsu Yi-Hsiang
- Hu Frank B
- Huang Huateng
- Huang Jinyan
- Hui Jennie
- Humphries Steve E
- Hundertmark Claudia
- Hung Yi-Jen
- Hunt Sarah E
- Hunt Steven C
- Hunter David J
- Husted Lise Bjerre
- Hveem Kristian
- Hwang Shih-Jen
- Hyppönen Elina
- Igl Wilmar
- Ikram M Arfan
- Illig Thomas
- Imboden Medea
- Ingelsson Erik
- Ingle Catherine
- Ingvarsson Thorvaldur
- Ioannidis John P A
- Iribarren Carlos
- Isaacs Aaron
- Isakova Tamara
- Islam Muhammad
- Ittermann Till
- Iwai Naoharu
- Jackson Anne U
- Jackson Rebecca
- Jacobs Gunnar
- Jafar Tazeen H
- James Alan L
- Jameson Karen A
- Jang Yangsoo
- Janipalli Charles S
- Jansen Hanneke
- Janssens A Cecile J W
- Jarvelin Marjo-Riitta
- Jeff Janina
- Jenny Nancy
- Johannsdottir Hrefna
- Johansen Berit
- Johansson Ingegerd
- Johansson Åsa
- Johnson Andrew
- Johnson Louise
- Johnson Paul C D
- Johnson Toby
- Jones Graeme
- Jones Michelle R
- Jousilahti Pekka
- Ju Sung Yun
- Jukema J Wouter
- Jula Antti
- Juliusdottir Thorhildur
- Justice Anne E
- Järvelin Marjo-Riitta
- Jöckel Karl-Heinz
- Kaakinen Marika
- Kahali Bratati
- Kalafati Ioanna-Panagiota
- Kaleebu Pontiano
- Kammerer Candace M
- Kanaya Alka
- Kang Hyun M
- Kang Hyun Min
- Kangas Antti J
- Kanoni Stavroula
- Kao Linda
- Kao W H L
- Kao Wen Hong Linda
- Kaplan Robert C
- Kaprio Jaakko
- Kaptoge Stephen K
- Kapur Karen A
- Karasik David
- Kardia Sharon L
- Karjalainen Juha
- Karlsson Magnus
- Karpe Fredrik
- Kastelein John J P
- Kathiresan Sekar
- Katsareli Efi
- Kedenko Lyudmyla
- Kee Frank
- Keildson Sarah
- Keinanen-Kiukaanniemi Sirkka M
- Keller Benjamin J
- Kemp John P
- Kennedy Stephen H
- Kessler Thorsten
- Kestenbaum Bryan
- Kesäniemi Antero
- Ketkar Shamika
- Kettunen Johannes
- Keyzer Jules
- Khaw Kay-Tee
- Khusainova Rita
- Khusnutdinova Elza
- Kiel Douglas P
- Kiess Wieland
- Kilpeläinen Tuomas O
- Kim Eric
- Kim Ghi Su
- Kim Hyo-Soo
- Kim Hyung-Lae
- Kim Stuart K
- Kinnunen Leena
- Kinra Sanjay
- Kiryluk Krzysztof
- Kita Yoshikuni
- Kivimaki Mika
- Kizer Jorge R
- Klaric Irena Martinovic
- Kleber Marcus E
- Klopp Norman
- Kloppenburg Margreet
- Knowles David
- Knowles Joshua W
- Kocarnik Jonathan
- Koenig Wolfgang
- Koh Jung-Min
- Kolcic Ivana
- Koller Daniel L
- Kollerits Barbara
- Kollia Panagoula
- Kolonel Laurence
- Kolovou Genovefa
- Komulainen Pirjo
- Kong Augustine
- Kooner Ishminder K
- Kooner Jaspal
- Kooperberg Charles
- Koromila Theodora
- Koudstaal Peter J
- Kovacs Peter
- Kraft Peter
- Kraja Aldi T
- Kramer Holly
- Kratzer Wolfgang
- Krauss Ronald M
- Krestyaninova Maria
- Kretzler Matthias
- Kristiansson Kati
- Kroemer Heyo K
- Kronenberg Florian
- Kruk Marcin
- Krämer Bernhard K
- Kuh Diana
- Kulkarni Smita R
- Kuller Lew
- Kumar M J Kranthi
- Kumari Meena
- Kung Annie Wai Chee
- Kutalik Zoltan
- Kutalik Zoltán
- Kuulasmaa Kari
- Kuusisto Johanna
- Kuznetsova Tatiana
- Kwan Tony
- Kytö Janne
- Kyvik Kirsten O
- Kähönen Mika
- König Inke R
- Körner Antje
- Köttgen Anna
- Laakso Markku
- Laaksonen Marika
- Laaksonen Reijo
- Laan Maris
- LaCroix Andrea
- Lacroix Andrea Z
- Ladenvall Claes
- Ladouceur Martin
- Lagou Vasiliki
- Lahermo Päivi
- Lahti Jari
- Lai Sandra
- Laisk Triin
- Laitinen Jaana
- Lajer Maria
- Lakatta Edward G
- Lakka Timo A
- Lambert Ann
- Lamina Claudia
- Langdahl Bente Lomholt
- Langefeld Carl D
- Langenberg Claudia
- Langford Cordelia
- Larson Martin
- Larson Martin G
- Lathrop Mark
- Lauc Lovorka Barac
- Launer Lenore
- Laven Joop S E
- Lawlor Debbie A
- Lawrence Robert W
- Le Marchand Loic
- Le Marchand Loïc
- Leak Tennille S
- Leander Karin
- Lecoeur Cecile
- Lee Ji-Young
- Lee Jong-Young
- Lee Nanette R
- Lee Sang Hong
- Lee Seung Hun
- Lefebvre Pierre
- Lehtimäki Terho
- Lehto Markku
- Leo Paul J
- Leslie William D
- Leung Ping C
- Levy Daniel
- Lewis Joshua R
- Li Guo
- Li Man
- Li Rui
- Li Shengxu
- Li Xiaohui
- Li Yali
- Liang Liming
- Lichtner Peter
- Lifton Richard P
- Lim Unhee
- Lin Danyu
- Lin Peng
- Lin Shih-Yi
- Lin Yi
- Lind Lars
- Lindgren Cecilia M
- Lindström Jaana
- Lips Paul
- Liu Ching-Ti
- Liu Jianjun
- Liu Yongmei
- Ljunggren Östen
- Lobbens Stéphane
- Locke Adam E
- Lohman Kurt
- Lohman Kurt K
- Lokki Marja-Liisa
- Longstreth W T
- Loo Britt-Marie
- Loos Ruth J F
- Lopez Lorna M
- Lorenc Roman S
- Lorentzon Mattias
- Louwers Yvonne V
- Lowe Christopher E
- Lu Xiaoning
- Luan Jian'an
- Luben Robert
- Lucas Gavin
- Ludwig Barbara
- Lumley Thomas
- Lundmark Anders
- Lundmark Per
- Lunetta Kathryn L
- Lyssenko Valeriya
- Lyytikainen Leo-Pekka
- Lyytikäinen Leo-Pekka
- Ma Baoshan
- MacCluer Jean
- Macgregor Stuart
- Mach François
- Maerz Winfried
- Maestroni Anna
- Maestroni Silvia
- Magnusson Patrik K E
- Mahajan Anubha
- Malinowski Jennifer
- Mangino Massimo
- Mani K Radha
- Manning Alisa K
- Manolio Teri
- Maouche Seraya
- Marc Janja
- Marette André
- Marmot Michael G
- Marongiu Mara
- Marre Michel
- Martin Finian
- Martin Nicholas G
- Marullo Letizia
- Masciullo Corrado
- Masi Laura
- Mateo Leach Irene
- Matise Tara
- Mattace-Raso Francesco U S
- Matullo Giuseppe
- Maxwell Alexander P
- McArdle Patick F
- McArdle Patrick F
- McArdle Wendy L
- McCarthy Mark I
- McCloskey Eugene
- McKay Gareth J
- McKenzie Colin A
- McKnight Amy J
- McKnight Amy Jayne
- McKnight Barbara
- McPherson Ruth
- Medina-Gomez Carolina
- Medina-Gómez Carolina
- Medland Sarah E
- Meduri Eshwar
- Meigs James B
- Meisinger Christa
- Meitinger Thomas
- Melander Olle
- Melbye Mads
- Mellström Dan
- Melzer David
- Mencej-Bedrac Simona
- Meneton Pierre
- Menni Cristina
- Merger Sigrun
- Meschia James F
- Metspalu Andres
- Metzger Marie
- Meulenbelt Ingrid
- Mihai Ioana
- Mihailov Evelin
- Miki Tetsuro
- Milaneschi Yuri
- Milani Lili
- Miljkovic Iva
- Mills Rebecca
- Min Josine L
- Minelli Cosetta
- Minster Ryan L
- Mirel Daniel B
- Missmer Stacey A
- Mitchell Braxton D
- Mitchell Paul
- Mitchell Sabrina L
- Moayyeri Alireza
- Moffatt Miriam F
- Mohlke Karen L
- Moilanen Leena
- Monda Keri L
- Monroe Kristine
- Montasser May E
- Montgomery Grant W
- Montgomery Stephen B
- Mooijaart Simon P
- Mooser Vincent
- Mora Samia
- Morken Mario A
- Morris Andrew D
- Morris Andrew P
- Morris Richard W
- Morrison Alanna C
- Mosley Thomas H
- Mota Eugen
- Mota Maria
- Mulas Antonella
- Munroe Patricia
- Murabito Joanne M
- Murdock Deborah
- Murgia Federico
- Murray Anna
- Murray Jeffrey C
- Murray Sarah S
- Musani Solomon
- Musk Arthur W
- Mychaleckyj Josyf C
- Mägi Reedik
- Mäkinen Ville-Petteri
- Männistö Satu
- März Winfried
- Möhlenkamp Stefan
- Möllsten Anna
- Mühleisen Thomas W
- Müller Gabriele
- Müller Gabrielle
- Müller-Nurasyid Martina
- Nagaraja Ramaiah
- Najjar Samer
- Nalls Michael A
- Nandakumar Kannabiran
- Narisu Narisu
- Nato Andrew
- Nauck Matthias
- Navarro Pau
- Navis Gerjan
- Nelis Mari
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- Yuan Xin
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- Zalloua Pierre A
- Zarrabeitia María T
- Zelenika Diana
- Zemunik Tatijana
- Zerbini Gianpaolo
- Zgaga Lina
- Zhai Guangju
- Zhang Feng
- Zhang Qunyuan
- Zhang Weihua
- Zhao Jing Hua
- Zhao Wei
- Zheng Hou-Feng
- Zheng Wei
- Zhou Yanhua
- Zhu Haidong
- Zhu Kun
- Zhu Xiaofeng
- Zhuang Wei V
- Zhuang Wei Vivian
- Ziegler Andreas
- Zillikens M Carola
- Zimmermann Martina E
- Zitting Paavo
- Zondervan Krina T
- Zukowska-Szczechowska Ewa
- Zygmunt Marek
- Ärnlöv Johan
- Österholm Anne-May
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms
Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study
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- Abel K
- Adamali H.
- Adeloye D
- Adeyemi Oluwaseun
- Adrego Rita
- Aguilar Jimenez Laura A.
- Ahmad Haider N
- Ahmad Shanaz
- Ahmed R
- Ahwireng Nyarko
- Ainsworth Mark
- Al-Sheklly B.
- Alamoudi Asma
- Alfaro-Almagro Fidel
- Ali Mariam
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- Allerton Lisa
- Allsop Lynne
- Allt Ann Marie
- Almeida Paula
- Altmann Danny
- Alvarez Corral Maria
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- Arbane Gill
- Arias Ava Maria
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- Koychev Ivan
- Kurasz Claire
- Kurupati Prathiba
- Laing C
- Lamlum Hanan
- Landers G
- Langenberg C
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- Lawrie Allan
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- Loosley Ronda
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- Lovegrove Wayne
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- Mangion K.
- Manisty Charlotte
- Manley R.
- March Katherine
- Marciniak S.
- Marino Philip
- Mariveles Myril
- Marks Michael
- Marouzet E
- Marsh Sophie
- Marshall B
- Marshall M
- Martin Jane
- Martineau A.
- Martinez L.M.
- Maskell Nick
- Matila Darwin
- Matimba-Mupaya Wadzanai
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- McMahon A.
- McMahon Michael J.
- McMorrow L
- Mcnally T
- McNarry M
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- McQueen Alison
- McShane H.
- Mears Chloe
- Megson Clare
- Megson Sharon
- Mehta P
- Meiring J
- Melling Lucy
- Mencias Mark
- Menke Ricarda
- Menzies Daniel
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- Michael Alice
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- Mohamed Abdelrahman
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- Moss Alastair J
- Moss P
- Motohashi K
- Msimanga N
- Mukaetova-Ladinska Elizabeta
- Munawar Unber
- Murira Jennifer
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- Needham Robert
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- Newman Tom
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- O'Brien Caitlin
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- Odell Natasha
- Ogbole Godwin
- Ogg G.
- Olaosebikan Olaoluwa
- Oliver Catherine
- Omar Zohra
- Openshaw Peter J.M.
- Orriss-Dib Lorna
- Osborne Lynn
- Osbourne Rebecca
- Ostermann Marlies
- Overton Charlotte
- Owen J.
- Oxton J
- Pack Jamie
- Pacpaco Edmund
- Paddick S.
- Painter Sharon
- Pakzad A
- Palmer Sue
- Papineni Padmasayee
- Paques K
- Paradowski Kerry
- Pareek Manish
- Parekh Dhruv
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- Pariante C.
- Parker S
- Parkes M.
- Parmar J
- Patale Sheetal
- Patel B.
- Patel Manish
- Patel Suhani
- Pattenadk Dibya
- Pavlides M.
- Payne Sheila
- Pearce Lorraine
- Pearl John E
- Peckham D.
- Pendlebury Jessica
- Peng Yanchun
- Pennington Chris
- Peralta Ida
- Perkins Emma
- Peterkin Z
- Peto T.
- Petousi Nayia
- Petrie J
- Pfeffer Paul
- Phipps Janet
- Piechnik Stefan K
- Pimm John
- Piper Hanley K.
- Pius R
- Plant Hannah
- Plein Sven
- Plekhanova Tatiana
- Plowright Megan
- Poinasamy Krisnah
- Polgar Oliver
- Poll L.
- Popescu Iulia
- Porter Joanna C
- Porter Julie
- Portukhay Sofiya
- Powell Natassia
- Prabhu A.
- Pratt James
- Price Andrea
- Price Carly
- Price Claire
- Price D.
- Price L
- Price L.
- Prickett A
- Prosper Sabrina
- Pugmire S.
- Quaid Sheena
- Quigley Jackie
- Quint Jennifer
- Qureshi H
- Qureshi I N
- Radhakrishnan K.
- Rahman Najib M.
- Ralser M
- Raman Betty
- Ramos Albert
- Ramos Hazel
- Rangeley Jade
- Rangelov B
- Ratcliffe L
- Ravencroft Phillip
- Reddington A
- Reddy A
- Reddy R.
- Redfearn H
- Redwood Dawn
- Reed Annabel
- Rees Meryl
- Rees Tabitha
- Regan Karen
- Reynolds W
- Ribeiro Carla
- Richards A.
- Richardson Emma
- Richardson Matthew
- Rivera-Ortega P.
- Roberts K.
- Robertson E.
- Robinson E
- Robinson Leanne
- Roche Lisa
- Roddis C
- Rodger J
- Rogers Natalie
- Ross Alexandra
- Ross Gavin
- Rossdale J.
- Rostron A
- Rowe Anna
- Rowland A
- Rowland J.
- Rowland Matthew J.
- Rowland-Jones Sarah L
- Roy K
- Roy Maura
- Rudan I
- Russell Emily
- Russell Richard
- Saalmink Gwen
- Sabit Ramsey
- Sage E.K.
- Samakomva T
- Samani Nilesh
- Samat Azlan Helmy A
- Sampson Claire
- Samuel Katherine
- Samuel R
- Sanders Zeena-Britt
- Sanderson Amy
- Sapey E
- Saralaya Dinesh
- Sargant J
- Sarginson C
- Sass T
- Sattar N
- Saunders Kathryn
- Saunders Laura C
- Saunders Peter
- Saunders Ruth M
- Savill Heather
- Saxon W.
- Sayer A.
- Schronce J.
- Schwaeble W
- Scott Janet T.
- Scott Kathryn
- Selby N.
- Semple Malcolm G.
- Sereno Marco
- Sewell Terri Ann
- Shah Ajay M
- Shah K.
- Shah P.
- Shankar-Hari M
- Sharma M
- Sharpe C.
- Sharpe M.
- Shashaa Sharlene
- Shaw Alison
- Shaw Karen
- Shaw V.
- Sheikh Aziz
- Shelton Sarah
- Shenton Liz
- Shevket K.
- Shikotra Aarti
- Short J
- Siddique Sulman
- Siddiqui Salman
- Sidebottom J
- Sigfrid L
- Simons G
- Simpson J.
- Simpson Neil
- Singapuri Amisha
- Singh Claire
- Singh Sally J
- Singh Suver
- Sissons D
- Skeemer J
- Slack Katie
- Smith Andrew
- Smith D.
- Smith Jacqui
- Smith Laurie
- Smith Nikki
- Smith Stephen
- Smith Susan
- Soares M
- Solano Teresa S
- Solly Reanne
- Solstice A.R.
- Soulsby T
- Southern David
- Sowter D
- Spears M
- Spencer L G
- Speranza Fabio
- Stadon Louise
- Stanel S
- Steeds Rick
- Steele N
- Steiner Mike
- Stensel D.
- Stephens G
- Stephenson Lorraine
- Stern M
- Stewart I
- Stimpson R
- Stockdale Sue
- Stockley J
- Stoker Wendy
- Stone Roisin
- Storrar Will
- Storrie Andrew
- Storton Kim
- Stringer E
- Strong-Sheldrake Sophia
- Stroud Natalie
- Subbe Christian
- Sudlow C L
- Suleiman Z
- Summers C
- Summersgill C
- Sutherland Debbie
- Sykes D.L.
- Sykes R.
- Talbot Nick
- Tan Ai Lyn
- Tarusan Lawrence
- Tavoukjian Vera
- Taylor Abigail
- Taylor Chris
- Taylor Jessica
- Te Amelie
- Tedd H.
- Tee Caroline
- Teixeira J
- Tench Helen
- Terry Sarah
- Thackray-Nocera Susannah
- Thaivalappil Favas
- Thamu B
- Thickett D
- Thomas Andrew K.
- Thomas Caradog
- Thomas David C.
- Thomas S.
- Thomas-Woods T.
- Thompson A A Roger
- Thompson T
- Thornton T
- Thorpe M
- Thwaites Ryan S.
- Tilley Jo
- Tinker N
- Tiongson Gerlynn F
- Tobin Martin
- Tomlinson Johanne
- Tong C
- Toshner Mark
- Touyz R.
- Treibel Thomas A
- Tripp K.A.
- Tunnicliffe Elizabeth M.
- Turnbull A
- Turner E
- Turner Kim
- Turner Sarah
- Turner Victoria
- Turney Sharon
- Turtle Lance
- Turton Helena
- Ugoji Jacinta
- Ugwuoke R
- Upthegrove R
- Valabhji J.
- Ventura M
- Vere Joanne
- Vickers Carinna
- Vinson B
- Wade Elaine
- Wade Phillip
- Wain Louise V
- Wainwright Tania
- Wajero Lilian O.
- Walder S
- Walker S
- Walker S.
- Wall E
- Wallis T
- Walmsley S
- Walsh J.A.
- Walsh S.
- Warburton Louise
- Ward T J C
- Warwick Katie
- Wassall Helen
- Waterson Samuel
- Watson Ekaterina
- Watson James
- Watson L.
- Webster M
- Weir-McCall Jonathan R
- Welch C
- Welch H.
- Welsh B.
- Wessely S.
- West Sophie
- Weston Heather
- Wheeler H
- White Sonia
- Whitehead Victoria
- Whitney J.
- Whittaker S
- Whittam Beverley
- Whitworth V
- Wight A
- Wild James M
- Wilkins M.
- Wilkinson D
- Williams B
- Williams Jenny
- Williams N
- Williams Nick
- Williams-Howard S.A.
- Willicombe M.
- Willis Gemma
- Willoughby J
- Wilson Ann
- Wilson D
- Wilson Imogen
- Window Nicola
- Witham M.
- Wolf-Roberts Rebecca
- Wood Chloe
- Woodhead F
- Woods Janet
- Wootton Daniel G.
- Wormleighton J
- Worsley J.
- Wraith D
- Wrey Brown Caroline
- Wright C.
- Wright L
- Wright S.
- Wyles J.
- Wynter Inez
- Xie Cheng
- Xu M
- Yasmin Najira
- Yasmin S
- Yates Tom
- Yip K P
- Young A.
- Young B.
- Young Susan
- Yousuf A J
- Zawia Amira
- Zeidan Lisa
- Zhao Bang
- Zheng Bang
- Zongo O.
- Publication venue
- Elsevier
- Publication date
- 22/09/2023
- Field of study
Introduction:
The multiorgan impact of moderate to severe coronavirus infections in the post-acute phase is still poorly understood. We aimed to evaluate the excess burden of multiorgan abnormalities after hospitalisation with COVID-19, evaluate their determinants, and explore associations with patient-related outcome measures.
Methods:
In a prospective, UK-wide, multicentre MRI follow-up study (C-MORE), adults (aged ≥18 years) discharged from hospital following COVID-19 who were included in Tier 2 of the Post-hospitalisation COVID-19 study (PHOSP-COVID) and contemporary controls with no evidence of previous COVID-19 (SARS-CoV-2 nucleocapsid antibody negative) underwent multiorgan MRI (lungs, heart, brain, liver, and kidneys) with quantitative and qualitative assessment of images and clinical adjudication when relevant. Individuals with end-stage renal failure or contraindications to MRI were excluded. Participants also underwent detailed recording of symptoms, and physiological and biochemical tests. The primary outcome was the excess burden of multiorgan abnormalities (two or more organs) relative to controls, with further adjustments for potential confounders. The C-MORE study is ongoing and is registered with ClinicalTrials.gov, NCT04510025.
Findings:
Of 2710 participants in Tier 2 of PHOSP-COVID, 531 were recruited across 13 UK-wide C-MORE sites. After exclusions, 259 C-MORE patients (mean age 57 years [SD 12]; 158 [61%] male and 101 [39%] female) who were discharged from hospital with PCR-confirmed or clinically diagnosed COVID-19 between March 1, 2020, and Nov 1, 2021, and 52 non-COVID-19 controls from the community (mean age 49 years [SD 14]; 30 [58%] male and 22 [42%] female) were included in the analysis. Patients were assessed at a median of 5·0 months (IQR 4·2–6·3) after hospital discharge. Compared with non-COVID-19 controls, patients were older, living with more obesity, and had more comorbidities. Multiorgan abnormalities on MRI were more frequent in patients than in controls (157 [61%] of 259 vs 14 [27%] of 52; p<0·0001) and independently associated with COVID-19 status (odds ratio [OR] 2·9 [95% CI 1·5–5·8]; padjusted=0·0023) after adjusting for relevant confounders. Compared with controls, patients were more likely to have MRI evidence of lung abnormalities (p=0·0001; parenchymal abnormalities), brain abnormalities (p<0·0001; more white matter hyperintensities and regional brain volume reduction), and kidney abnormalities (p=0·014; lower medullary T1 and loss of corticomedullary differentiation), whereas cardiac and liver MRI abnormalities were similar between patients and controls. Patients with multiorgan abnormalities were older (difference in mean age 7 years [95% CI 4–10]; mean age of 59·8 years [SD 11·7] with multiorgan abnormalities vs mean age of 52·8 years [11·9] without multiorgan abnormalities; p<0·0001), more likely to have three or more comorbidities (OR 2·47 [1·32–4·82]; padjusted=0·0059), and more likely to have a more severe acute infection (acute CRP >5mg/L, OR 3·55 [1·23–11·88]; padjusted=0·025) than those without multiorgan abnormalities. Presence of lung MRI abnormalities was associated with a two-fold higher risk of chest tightness, and multiorgan MRI abnormalities were associated with severe and very severe persistent physical and mental health impairment (PHOSP-COVID symptom clusters) after hospitalisation.
Interpretation:
After hospitalisation for COVID-19, people are at risk of multiorgan abnormalities in the medium term. Our findings emphasise the need for proactive multidisciplinary care pathways, with the potential for imaging to guide surveillance frequency and therapeutic stratification
Using trained dogs and organic semi-conducting sensors to identify asymptomatic and mild SARS-CoV-2 infections: an observational study
- Author
- Adlakha Sanjay
- Agwuh Kenneth
- Allen David J
- Allsop Lynne
- Alvarez Ana
- Andrews Robert
- Arenas-Pinto Alejandro
- Assis Ana
- Aziz Catherine
- Aziz Sophie
- Baerenbold Oliver
- Beadle Shannen
- Begum Safia
- Bergstrom Malin
- Boffito Marta
- Borthwick Ewan
- Bradley John
- Buckley Philip
- Buckley Sarah
- Burns Karen
- Campbell Alison
- Care Helen
- Carey Peter
- Cartwright Jo-anne
- Castle Gail
- Caton Laura
- Chabildas Unnati
- Chaudhary Zain
- Chen-Hussey Vanessa
- Clifford Samuel
- Cook Natalie
- Cotterell Bryony
- Cottis Luke
- Crasto Winston Andrew
- Cruickshank Irena
- Curtis Emily
- Davis Jane
- De Wilton Angus
- Dennehy Jessica
- Dewhirst Sarah Y
- Dodgson Andrew
- Dowse Claire
- Edwards Rachel
- Egbuniwe Obi
- Evans Jessica
- Fernandez Candida
- Fletcher Aimee
- Foley Erin
- Forsey Miranda
- Forster Kate
- Frankland Lisa
- Gaskell Kate
- Gezan Salvador A
- Gibson Tim
- Glasgow Susannah
- Goodsell Kerry
- Greaves Courtenay K
- Guerdette Anne-Marie
- Guest Claire
- Hazelton Tracey
- Heal Janette
- Hewitt Claire
- Higham Andrew
- Hill David
- Hind Daniel
- Holbrook Sara
- Holland Maureen
- Houlihan Catherine
- Hutchins Harry
- Jahan Nazifa
- Johnson Cecelia
- Jones Imogen
- Jones Julie
- Jones Robert
- Kadiu Denise
- Kane Patricia
- Kaye Angela
- Keenan Natalie
- Kirkpatrick Emily
- Kisha Sarah
- Kittridge Lauren
- Kleinschmidt Immo
- Laird Steve
- Lake Judith
- Lambert Sébastien
- Last Anna
- Lawrence Tara
- Le Bas Julie
- Ledeatte Williams Zaena
- Leeman Lucy
- Lenton Daniel
- Lindley Kate
- Lindsay Steve W
- Logan James G
- Lopuszansky Orianne
- Lowry Tracey
- Lupton Stephanie
- Mackenzie Nicola
- Makepeace Alan
- Margaritis Marios
- Mart Robert
- Matthews Rebecca
- Maxwell Veronica
- Miralhes Patricia
- Moar Robert
- Morant Steve
- Musanhu Rosemary
- Netherton Kimberley
- Nicholson Anne
- Oddy Sharon
- Oommen Anu
- Oultram Sally-Anne
- Owens Leah
- Owonibi Tolulope
- O’Toole Sarah
- Parker Josephine EA
- Peeling Rosanna
- Pickett John
- Prabhu Joshi
- Prymas Paulina
- Purcell Benjamin
- Pursell Molly
- Quilty Billy J
- Ramos Angelo
- Rampling Tommy
- Rand James
- Rangeley Jade
- Rickman Hannah
- Ritches Joanne
- Rixson Christopher
- Roebuck Alun
- Rooney Ann
- Rudge Karen
- Ryan Courteney
- Ryder Stephen
- Saalmink Gwendolyn
- Schumacher Natasha
- Scriven James
- Setty Niranjan
- Severn Abigail
- Shah Manil
- Shaw Amber
- Shenton Fiona
- Shephardson Sarah
- Slater Lynda
- Smith Jayde
- Smith Susan
- Somerville Mark
- Sowter Donna
- Spencer Freya
- Squires Chelci
- Stefanidis Anastasios
- Stewart Sophie
- Storr Emma
- Sylvester Martin
- Thatcher Hilary
- Thompson Catherine
- Topham Kirsty
- Tsaknis George
- Turner Jane
- Turns Margaret
- Tytheridge Scott
- Vertue Mark
- Wainwright Tania
- Wakley Sian
- Walker Martin
- Walker Rebecca
- Walsh Joanne
- Walton Hollie
- Wassall Helen
- West Raha
- Wildman Shanice
- Wilson Anne
- Young Megan
- Publication venue
- Oxford University Press
- Publication date
- 01/01/2022
- Field of study
Background A rapid, accurate, non-invasive diagnostic screen is needed to identify people with SARS-CoV-2 infection. We investigated whether organic semi-conducting (OSC) sensors and trained dogs could distinguish between people infected with asymptomatic or mild symptoms, and uninfected individuals, and the impact of screening at ports-of-entry. Methods Odour samples were collected from adults, and SARS-CoV-2 infection status confirmed using RT-PCR. OSC sensors captured the volatile organic compound (VOC) profile of odour samples. Trained dogs were tested in a double-blind trial to determine their ability to detect differences in VOCs between infected and uninfected individuals, with sensitivity and specificity as the primary outcome. Mathematical modelling was used to investigate the impact of bio-detection dogs for screening. Results About, 3921 adults were enrolled in the study and odour samples collected from 1097 SARS-CoV-2 infected and 2031 uninfected individuals. OSC sensors were able to distinguish between SARS-CoV-2 infected individuals and uninfected, with sensitivity from 98% (95% CI 95–100) to 100% and specificity from 99% (95% CI 97–100) to 100%. Six dogs were able to distinguish between samples with sensitivity ranging from 82% (95% CI 76–87) to 94% (95% CI 89–98) and specificity ranging from 76% (95% CI 70–82) to 92% (95% CI 88–96). Mathematical modelling suggests that dog screening plus a confirmatory PCR test could detect up to 89% of SARS-CoV-2 infections, averting up to 2.2 times as much transmission compared to isolation of symptomatic individuals only. Conclusions People infected with SARS-CoV-2, with asymptomatic or mild symptoms, have a distinct odour that can be identified by sensors and trained dogs with a high degree of accuracy. Odour-based diagnostics using sensors and/or dogs may prove a rapid and effective tool for screening large numbers of people
Annals, Volume 106 Index
- Author
- Aitken Stuart C.
- Alderman Derek H.
- Baics Gergely
- Baker Tom
- Barnes Trevor J.
- Bergmann Luke
- Best Asha
- Birenboim Amit
- Bissell David
- Brannstrom Christian
- Bryan Joe
- Büscher Bram
- Carlisle Liz
- Carrier Mathieu
- Carrier Mathieu
- Cidell Julie
- Clark Jessie Hanna
- Cope Meghan
- Curtis Andrew
- Cutter Susan L.
- Cutter Susan L.
- Delmelle Elizabeth C.
- Dempsey Jessica
- Dong Guanpeng
- Eidse Noelani
- Ellis Mark
- Evans Alice
- Grace Kathryn
- Griffith Daniel A.
- Grinblat Yulia
- Grinblat Yulia
- Harrison Conor
- Herrick Clare
- Hodder Jake
- Hodder Jake
- Horowitz Leah S.
- Hu Yujie
- Inwood Joshua
- Ishikawa Toru
- Jiang Penghui
- Jiang Penghui
- Johnston Ron
- Karimi Ali
- Kavanagh Leo
- Kavanagh Leo
- Kingsbury Paul
- Knapp Paul A.
- Koopman Sara
- Kordi Maryam
- Kwan Mei-Po
- Kwan Mei-Po
- Larson Phillip H.
- Larson Phillip H.
- Lee Neil
- Lejano Raul P.
- Logan John R.
- Long Ying
- Lorimer Jamie
- Luehmann Michael D.
- Maldonado Marta Maria
- Margulies Jared D.
- Mason Michael
- Mason Michael
- Mburu Lucy W.
- McGuirk Pauline M.
- Miller Byron
- Mohammad Robina
- Mohammad Robina
- Nathan Green W.
- Naybor Deborah
- Neil Adger W.
- O'Lear Shannon
- Ong Xueyuan
- Parks Virginia
- Porter Gina
- Preston Valerie
- Price Marie
- Pryce Gwilym
- Pryce Gwilym
- Qiao Jiajun
- Rey Sergio J.
- Ritterbusch Amy E.
- Rowen Ian
- Schultze Steven R.
- Shannon Jerry
- Shaw Ian G. R.
- Sheller Mimi
- Shen Jianfa
- Shen Jianfa
- Sheppard Eric
- Sieber Renée E.
- Spinney Justin
- Staeheli Lynn A.
- Stratford Elaine
- Swanlund David
- van Blerk Lorraine
- Vitale Patrick
- Vitale Patrick
- Wainwright Joel D.
- Weaver Russell
- Winkler Julie A.
- Winkler Julie A.
- Wu Wenjie
- Xu Yang
- Yea Sallie
- Zhong Shiran
- Zhong Shiran
- Zhong Shiran
- Zick Stephanie E.
- Zick Stephanie E.
- Zolnik Edmund J.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Die Pathologie der Avitaminosen und Hypervitaminosen
- Author
- A Albeggiani
- A Aschkenasy
- A Bennandi
- A Brown
- A Brusa
- A Carlsson
- A Carotene
- A Chevallier
- A Chevallier
- A Corcos
- A Cruchaud
- A Dagianti
- A Dury
- A Faller
- A Faller
- A Ferraro
- A Fingerland
- A Forse
- A Froehlich
- A Gellhorn
- A Gellhorn
- A Gerber
- A Gerber
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Golden
- A Grimm
- A Heise
- A Hirt
- A Hoffer
- A Holst
- A Holst
- A Ingelmansundberg
- A Ingelmansundberg
- A Issidorides
- A JuhaszschÄFfer
- A JuhaszschÄFfer
- A Kirschbaum
- A Kornberg
- A Kornberg
- A Kornberg
- A Kornberg
- A Krupski
- A Krupski
- A Libretti
- A Mariakulandai
- A Matet
- A Mex
- A Minkowski
- A Minkowski
- A Morelli
- A MUsIni
- A Narrozzi
- A Narrozzi
- A Pirie
- A Pirie
- A Pittoni
- A Prader
- A Schleich
- A Sesmarais
- A Steiger
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Szentgyorgy
- A Tannenbaum
- A Tannenbaum
- A Taylor
- A Taylor
- A Terbruggen
- A Volta
- A Werthemann
- A Werthemann
- A Windaus
- A Wolf
- A Wolf
- A. H. Douthwaite
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AB Benchimol
- AB Kar
- AB Sabin
- AB Vogelsang
- AB Vogelsang
- AB Watts
- AB Watts
- AC Allison
- AC Barnes
- AC Barnes
- AC Silva
- AC Upton
- AC Upton
- AC Upton
- AC Wiese
- AC Wiese
- AC Wiese
- AD Gillanders
- AD Laurence
- AD Welch
- AE Axelrod
- AE Axelrod
- AE Axelrod
- AE Axelrod
- AE Axelrod
- AE Axelrod
- AE Axelrod
- AE Schaefer
- AE Schaefer
- AE Schaefer
- AE Schaefer
- AE Schaefer
- AE Schaefer
- AE Schaefer
- AE Schaefer
- AF Hess
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- SB Wolrach
- SC Chang
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- SC Stothers
- SE Goldzier
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- SG Smith
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- SK Elster
- SQ Cohlan
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- SQ Cohlan
- SQ Conman
- SR Ames
- SR Ames
- SR Ames
- SR Ames
- SR Ames
- SS Chernick
- SS Chernick
- SS Spicer
- SS Spicer
- SS Turesky
- SS Turesky
- SS Turesky
- SW Clausen
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SY Pan
- T Barlow
- T Barlow
- T Barlow
- T Gillman
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- T Gordonoff
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- TM Ferguson
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- TR Riggs
- TS Argyris
- TW Gullickson
- TW Gullicxson
- Untersuchungen über die Wirksamkeit des Vitamins BB (Pyridoxin) bei diphtherischen Lähmungen
- V Claassen
- V Demole
- V Demole
- V Demole
- V Demole
- V Demole
- V Piccioni
- V Ramalingasfami
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- V Spampinato
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- V. L. Hart
- VA Drill
- VD Vigneaud
- VE Kinsey
- VN Patfardhan
- W Antopol
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- W Dittrich
- W Eger
- W Ehrengut
- W Ehrengut
- W Fey
- W Goettscii
- W Hessler
- W Hohlweg
- W Hohlweg
- W Kircher
- W Kwiatkowski
- W Landauer
- W Landauer
- W Loffler
- W Marusich
- W Mcfarland
- W Montagna
- W Montagna
- W Muller
- W Neuweiler
- W Neuweiler
- W Neuweiler
- W Neuweiler
- W Neuweiler
- W Neuweiler
- W Neuweiler
- W Neuweiler
- W Rozynek
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Salmon
- W Sebrell
- W Stepp
- W Stepp
- W Stepp
- W Swoboda
- W Tobler
- W Trager
- W Trager
- W. E. Shute
- W. F. Alexander
- W. W. Fox
- WA Grimes
- WA Krehl
- WA Krehl
- WB Atkinson
- WB Atkinson
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- WB Robertson
- WB Robertson
- WB Robertson
- WC Aalsmeer
- WC Owens
- WC Russell
- WC Thomas
- WD King
- WD Salmon
- WD Salmon
- WD Salmon
- WD Salmon
- WE Germeraad
- WE Germeraad
- WE Loch
- WE Phillips
- WE Shute
- WF Abercrombie
- WF Orr
- WF Perry
- WG Casselman
- WG Casselman
- WG Hoekstra
- WG Hoekstra
- WG Jaffe
- WG Jaffe
- WG Jaffe
- WG Jaffe
- WH Eddy
- WH Fishman
- WH Fishman
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Jr
- WH Sebrell
- WH Sebrell
- WH Sebrell
- WH Sebrell
- WJ Darby
- WJ Emerson
- WJ Griffiths
- WJ Mcganity
- WK Hall
- WK Manning
- WL Money
- WL Money
- WL Money
- WL Williams
- WM Booker
- WM Booker
- WO Brown
- WO Motte
- WO Russell
- WO Russell
- WO Russell
- WP Covell
- WP Covell
- WP Lehrer
- WR Ruegamer
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WT Wong
- WV Drigalski
- WW Cravens
- WW Cravens
- WW Cravens
- WW Cravens
- WW Crnvens
- WW Crnvens
- WW Crnvens
- WW Hawkins
- WW Hawkins
- WW Hawkins
- WW Hawkins
- WW Wainwright
- Y Hosoya
- Y Raoul
- YO Chang
- Z Menschik
- Z Menschik
- Z Menschik
- Z Menschir
- ZM Bacq
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1962
- Field of study
Genetic studies of body mass index yield new insights for obesity biology
- Author
- Aasarød K
- Abecasis G
- Abecasis GR
- Abecasis GR
- Abecasis Gonçalo R.
- Absher D
- Absher D
- Absher Devin
- Adair LS
- Adair LS
- Adair LS
- Adair Linda S.
- Adam M
- Adeyemo A
- Ahlqvist E
- Ahmadi KR
- Ahola A
- Ainali C
- Akylbekova E
- Ala-Korpela M
- Alavere H
- Albrecht E
- Albrecht E
- Albrecht Eva
- Alexander M
- Alhenc-Gelas F
- Alizadeh BZ
- Alizadeh BZ
- Altshuler D
- Altshuler D
- Altshuler D
- Altshuler D
- Ambite JL
- Amin N
- Amin N
- Amin Najaf
- Amouyel P
- Amouyel Philippe
- An P
- Anand S
- Anand S
- Anderson CA
- Anderson G
- Anderson Denise
- Andrews JS
- Andrews JS
- Antonella M
- Antti J
- Ardissino D
- Ardissino D
- Ardissino D
- Arking DE
- Arking DE
- Arnold A
- Arnold AM
- Arora P
- Arscott Gillian M.
- Artigas MS
- Arveiler D
- Arveiler D
- Arveiler Dominique
- Asiki G
- Aspelund T
- Aspelund T
- Aspelund T
- Aspelund T
- Aspelund T
- Asselbergs Folkert W.
- Asselta R
- Assimes TL
- Assimes TL
- Assimes Themistocles L.
- Atalay M
- Atkinson EJ
- Atkinson EJ
- Attwood Antony P.
- Aulchenko Y
- Aulchenko YS
- Avery C
- Bain SC
- Bakker SJ
- Bakker SJ
- Bakker SJ
- Bakker Stephan J.L.
- Balkau B
- Ball SG
- Balmforth AJ
- Balmforth AJ
- Bandinelli S
- Bandinelli S
- Bandinelli S
- Bandinelli S
- Bandinelli S
- Bandinelli Stefania
- Barbalic M
- Barrett A
- Barrett Amy
- Barroso I
- Barroso I
- Barroso I
- Barroso I
- Barroso I
- Barroso Inɥs
- Bas Isabelita N.
- Basart H
- Basart HV
- Bataille V
- Baumert J
- Beckmann JS
- Beckmann JS
- Beckmann JS
- Beckmann JS
- Beckmann JS
- Beckmann Jacques S.
- Beekman Marian
- Been LF
- Beilby JP
- Beilby JP
- Beilby John
- Bell JT
- Bellis Claire
- Bennett F
- Bennett Amanda J.
- Berenson GS
- Berger K
- Berglund G
- Bergman RN
- Bergman RN
- Bergman Richard N.
- Bergmann S
- Bergmann S
- Bergmann S
- Bergmann S
- Bernardi F
- Bernardinelli L
- Berndt Sonja I.
- Berne Christian
- Berzuini C
- Bielak LF
- Bierut LJ
- Biffar R
- Biffar R
- Bis JC
- Blackburn H
- Blagieva Roza
- Blangero John
- Blankenberg SS
- Blüher Matthias
- Boban M
- Boban M
- Bochud M
- Bochud M
- Bochud M
- Bochud M
- Bochud M
- Bochud Murielle
- Boehm BO
- Boehm BO
- Boehm BO
- Boehm Bernhard O.
- Boehnke M
- Boehnke M
- Boehnke M
- Boehnke M
- Boehnke Michael
- Boerwinkle E
- Boerwinkle E
- Boerwinkle E
- Boerwinkle E
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- Zerbini G
- Zgaga L
- Zgaga L
- Zhai G
- Zhai G
- Zhai G
- Zhang F
- Zhang W
- Zhang W
- Zhang W
- Zhang Qunyuan
- Zhang Weihua
- Zhao JH
- Zhao JH
- Zhao JH
- Zhao JH
- Zhao W
- Zhao Jing Hua
- Zhao Wei
- Zheng W
- Zheng Wei
- Zhu H
- Zhu X
- Zhuang WV
- Zhuang WV
- Ziegler A
- Ziegler A
- Ziegler A
- Zillikens MC
- Zillikens M. Carola
- Zimmermann ME
- Zitting P
- Zondervan KT
- Zondervan KT
- Zondervan Krina T.
- Zonzin P
- Zukowska-Szczechowska E
- Zygmunt M
- Ärnlöv J
- Ärnlöv Johan
- Österholm AM
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Note: A full list of authors and affiliations appears at the end of the article.
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P 20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.</p