Ameloblastic fibroma: a rare case appearing as a mixed radiographic image

Ameloblastic fibroma (AF) is a benign tumor of mixed odontogenic origin, which affects predominantly young individuals. AF appearing as a mixed radiographic image is very rare. This report describes a case of AF in a 12- year-old male identified during a routine radiographic exam for orthodontic treatment planning. The panoramic radiography revealed a well-defined multilocular mixed image located in the mandible between the roots of the left mandibular second premolar and first molar. The lesion was excised under local anesthesia. Histopathological analysis revealed islands of epithelial cells and columnar peripheral cells showing a nucleus in inverted polarization, interspersed with spindle-shaped cells and abundant extracellular matrix deposition. No atypia was observed. The diagnosis of AF was established. No tumor recurred up to 30 months after treatment. Although rare, AF should be also considered in the differential diagnosis of mixed radiographic images of the jaws in young patients

Perfil epidemiológico dos pacientes com Zika Vírus em Marabá (PA) entre 2016 e 2021

O Zika Vírus (ZIKV) é um arbovírus da família Flaviviridae, que possui duas cepas — asiática e africana. Em 2016, ele se tornou uma doença de notificação obrigatória no Brasil. Desde então, uma multiplicidade de fatores envolveu a representação da doença, incluindo seus aspectos sociais e coletivos. Nesse contexto, com o objetivo de elucidar as diferentes particularidades do interior paraense, o presente trabalho tem como finalidade conhecer o panorama epidemiológico dos pacientes com Zika Vírus, notificados no município de Marabá (PA). Trata-se de um estudo retrospectivo e transversal, com uma análise temporal de dados secundários dos casos de Zika Vírus, no período de 2016 a 2021. A partir dos dados colhidos, a faixa etária mais afetada foi entre pessoas de 20 a 39 anos, do sexo feminino, de raça parda, com ensino médio completo e de critério laboratorial, que, majoritariamente, seguiram com a cura. Torna-se evidente a importância das notificações de casos de forma mais detalhada, afim de definir o cenário epidemiológico de uma região e garantir esforços para amenizar a situação de áreas mais afetadas. Assim, será possível a promoção de medidas de intervenção mais diretas, tornando a população mais favorecida e o conhecimento científico mais amplo

Performance of vertical jumps in defensive and offensive female footballplayers

O futebol feminino está crescendo no Brasil e estudos que avaliem o desempenho físico das atletas permitem criar parâmetros para a modalidade. O objetivo do presente estudo foi descrever as variáveis dos saltos verticais em atletas de futebol feminino e realizar a comparação entre atletas defensivas e ofensivas. A amostra foi constituída de 16 atletas de futebol do sexo feminino. Foram avaliados os dados antropométricos, a posição tática e os saltos verticais. Foram coletados saltos squat jump (SJ) e counter movement jump (CMJ) com o aplicativo MyJump. As atletas de futebol avaliadas apresentaram em média 24,33±3,71 cm de altura e 19,69±3,25 W/kg de potência para o salto SJ. Além disso, apresentaram 24,25±4,09 cm de altura e 19,67±3,59 W/kg de potência para o salto CMJ. Em relação à razão CMJ/SJ, o valor apresentado foi de 1,00±0,08. As variáveis avaliadas nos saltos verticais não apresentaram diferenças entre as atletas de futebol defensivase ofensivas (p>0,05). Assim, as atletas apresentaram aproximadamente 24 cm de altura e 19 W/kg de potência para os saltos, com baixa contribuição do ciclo alongamento-encurtamento para essas ações. Por fim, as atletas de futebol feminino das posições defensivas apresentaram desempenho semelhante às ofensivas nos saltos verticais.Women's footballis growing in Brazil and studies that assess the physical performance of the players allow to create parameters for the sport. The aim of the present study was to describe the variables of vertical jumps in female footballplayers and to compare defensive and offensive players. The sample was consisted of 18 female footballplayers. Anthropometric data, tactical position and vertical jumps were evaluated. Squat jump (SJ) and counter movement jump (CMJ) jumps were collected with the MyJump application. The footballplayers evaluated showed an average of 24.33±3.71 cm in height and 19.69±3.25 W/kg of power for the SJ. In addition, they performed 24.25±4.09 cm in height and 19.67±3.59 W/kg of power for the CMJ. Regarding to CMJ/SJ ratio, the value was 1.00±0.08. There were no differences between backwards and forwards footballplayers in all variables evaluated in the vertical jumps (p>0.05). Thus, the players presented approximately 24 cm in height and 19 W/kg of power for the jumps, with a low contribution of the stretching-shortening cycle for these actions. Finally, female footballplayers in backwards positions performed similarly to forwards players in vertical jumps

SARS-CoV-2 uses CD4 to infect T helper lymphocytes

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the agent of a major global outbreak of respiratory tract disease known as Coronavirus Disease 2019 (COVID-19). SARS-CoV-2 infects mainly lungs and may cause several immune-related complications, such as lymphocytopenia and cytokine storm, which are associated with the severity of the disease and predict mortality. The mechanism by which SARS-CoV-2 infection may result in immune system dysfunction is still not fully understood. Here, we show that SARS-CoV-2 infects human CD4+ T helper cells, but not CD8+ T cells, and is present in blood and bronchoalveolar lavage T helper cells of severe COVID-19 patients. We demonstrated that SARS-CoV-2 spike glycoprotein (S) directly binds to the CD4 molecule, which in turn mediates the entry of SARS-CoV-2 in T helper cells. This leads to impaired CD4 T cell function and may cause cell death. SARS-CoV-2-infected T helper cells express higher levels of IL-10, which is associated with viral persistence and disease severity. Thus, CD4-mediated SARS-CoV-2 infection of T helper cells may contribute to a poor immune response in COVID-19 patients.</p

SARS-CoV-2 uses CD4 to infect T helper lymphocytes

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the agent of a major global outbreak of respiratory tract disease known as Coronavirus Disease 2019 (COVID-19). SARS-CoV-2 infects mainly lungs and may cause several immune-related complications, such as lymphocytopenia and cytokine storm, which are associated with the severity of the disease and predict mortality. The mechanism by which SARS-CoV-2 infection may result in immune system dysfunction is still not fully understood. Here, we show that SARS-CoV-2 infects human CD4+ T helper cells, but not CD8+ T cells, and is present in blood and bronchoalveolar lavage T helper cells of severe COVID-19 patients. We demonstrated that SARS-CoV-2 spike glycoprotein (S) directly binds to the CD4 molecule, which in turn mediates the entry of SARS-CoV-2 in T helper cells. This leads to impaired CD4 T cell function and may cause cell death. SARS-CoV-2-infected T helper cells express higher levels of IL-10, which is associated with viral persistence and disease severity. Thus, CD4-mediated SARS-CoV-2 infection of T helper cells may contribute to a poor immune response in COVID-19 patients.</p

Measurement of the polarisation of W bosons produced with large transverse momentum in pp collisions at sqrt(s) = 7 TeV with the ATLAS experiment

This paper describes an analysis of the angular distribution of W->enu and W->munu decays, using data from pp collisions at sqrt(s) = 7 TeV recorded with the ATLAS detector at the LHC in 2010, corresponding to an integrated luminosity of about 35 pb^-1. Using the decay lepton transverse momentum and the missing transverse energy, the W decay angular distribution projected onto the transverse plane is obtained and analysed in terms of helicity fractions f0, fL and fR over two ranges of W transverse momentum (ptw): 35 < ptw < 50 GeV and ptw > 50 GeV. Good agreement is found with theoretical predictions. For ptw > 50 GeV, the values of f0 and fL-fR, averaged over charge and lepton flavour, are measured to be : f0 = 0.127 +/- 0.030 +/- 0.108 and fL-fR = 0.252 +/- 0.017 +/- 0.030, where the first uncertainties are statistical, and the second include all systematic effects.Comment: 19 pages plus author list (34 pages total), 9 figures, 11 tables, revised author list, matches European Journal of Physics C versio

Observation of a new chi_b state in radiative transitions to Upsilon(1S) and Upsilon(2S) at ATLAS

The chi_b(nP) quarkonium states are produced in proton-proton collisions at the Large Hadron Collider (LHC) at sqrt(s) = 7 TeV and recorded by the ATLAS detector. Using a data sample corresponding to an integrated luminosity of 4.4 fb^-1, these states are reconstructed through their radiative decays to Upsilon(1S,2S) with Upsilon->mu+mu-. In addition to the mass peaks corresponding to the decay modes chi_b(1P,2P)->Upsilon(1S)gamma, a new structure centered at a mass of 10.530+/-0.005 (stat.)+/-0.009 (syst.) GeV is also observed, in both the Upsilon(1S)gamma and Upsilon(2S)gamma decay modes. This is interpreted as the chi_b(3P) system.Comment: 5 pages plus author list (18 pages total), 2 figures, 1 table, corrected author list, matches final version in Physical Review Letter

Search for displaced vertices arising from decays of new heavy particles in 7 TeV pp collisions at ATLAS

We present the results of a search for new, heavy particles that decay at a significant distance from their production point into a final state containing charged hadrons in association with a high-momentum muon. The search is conducted in a pp-collision data sample with a center-of-mass energy of 7 TeV and an integrated luminosity of 33 pb^-1 collected in 2010 by the ATLAS detector operating at the Large Hadron Collider. Production of such particles is expected in various scenarios of physics beyond the standard model. We observe no signal and place limits on the production cross-section of supersymmetric particles in an R-parity-violating scenario as a function of the neutralino lifetime. Limits are presented for different squark and neutralino masses, enabling extension of the limits to a variety of other models.Comment: 8 pages plus author list (20 pages total), 8 figures, 1 table, final version to appear in Physics Letters

Standalone vertex finding in the ATLAS muon spectrometer

A dedicated reconstruction algorithm to find decay vertices in the ATLAS muon spectrometer is presented. The algorithm searches the region just upstream of or inside the muon spectrometer volume for multi-particle vertices that originate from the decay of particles with long decay paths. The performance of the algorithm is evaluated using both a sample of simulated Higgs boson events, in which the Higgs boson decays to long-lived neutral particles that in turn decay to bbar b final states, and pp collision data at √s = 7 TeV collected with the ATLAS detector at the LHC during 2011

Measurements of Higgs boson production and couplings in diboson final states with the ATLAS detector at the LHC

Measurements are presented of production properties and couplings of the recently discovered Higgs boson using the decays into boson pairs, H →γ γ, H → Z Z∗ →4l and H →W W∗ →lνlν. The results are based on the complete pp collision data sample recorded by the ATLAS experiment at the CERN Large Hadron Collider at centre-of-mass energies of √s = 7 TeV and √s = 8 TeV, corresponding to an integrated luminosity of about 25 fb−1. Evidence for Higgs boson production through vector-boson fusion is reported. Results of combined fits probing Higgs boson couplings to fermions and bosons, as well as anomalous contributions to loop-induced production and decay modes, are presented. All measurements are consistent with expectations for the Standard Model Higgs boson