Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020

We show the distribution of SARS-CoV-2 genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three available genomic nomenclature systems for SARS-CoV-2 to all sequence data from the WHO European Region available during the COVID-19 pandemic until 10 July 2020. We highlight the importance of real-time sequencing and data dissemination in a pandemic situation. We provide a comparison of the nomenclatures and lay a foundation for future European genomic surveillance of SARS-CoV-2.Peer reviewe

Study of the lineshape of the chi(c1) (3872) state

A study of the lineshape of the chi(c1) (3872) state is made using a data sample corresponding to an integrated luminosity of 3 fb(-1) collected in pp collisions at center-of-mass energies of 7 and 8 TeV with the LHCb detector. Candidate chi(c1)(3872) and psi(2S) mesons from b-hadron decays are selected in the J/psi pi(+)pi(-) decay mode. Describing the lineshape with a Breit-Wigner function, the mass splitting between the chi(c1 )(3872) and psi(2S) states, Delta m, and the width of the chi(c1 )(3872) state, Gamma(Bw), are determined to be (Delta m=185.598 +/- 0.067 +/- 0.068 Mev,)(Gamma BW=1.39 +/- 0.24 +/- 0.10 Mev,) where the first uncertainty is statistical and the second systematic. Using a Flatte-inspired model, the mode and full width at half maximum of the lineshape are determined to be (mode=3871.69+0.00+0.05 MeV.)(FWHM=0.22-0.04+0.13+0.07+0.11-0.06-0.13 MeV, ) An investigation of the analytic structure of the Flatte amplitude reveals a pole structure, which is compatible with a quasibound D-0(D) over bar*(0) state but a quasivirtual state is still allowed at the level of 2 standard deviations

Measurement of the CKM angle γγ in B±→DK±B^\pm\to D K^\pm and B±→Dπ±B^\pm \to D π^\pm decays with D→KS0h+h−D \to K_\mathrm S^0 h^+ h^-

A measurement of $CP$-violating observables is performed using the decays $B^\pm\to D K^\pm$ and $B^\pm\to D \pi^\pm$, where the $D$ meson is reconstructed in one of the self-conjugate three-body final states $K_{\mathrm S}\pi^+\pi^-$ and $K_{\mathrm S}K^+K^-$ (commonly denoted $K_{\mathrm S} h^+h^-$). The decays are analysed in bins of the $D$-decay phase space, leading to a measurement that is independent of the modelling of the $D$-decay amplitude. The observables are interpreted in terms of the CKM angle $\gamma$. Using a data sample corresponding to an integrated luminosity of $9\,\text{fb}^{-1}$ collected in proton-proton collisions at centre-of-mass energies of $7$, $8$, and $13\,\text{TeV}$ with the LHCb experiment, $\gamma$ is measured to be $\left(68.7^{+5.2}_{-5.1}\right)^\circ$. The hadronic parameters $r_B^{DK}$, $r_B^{D\pi}$, $\delta_B^{DK}$, and $\delta_B^{D\pi}$, which are the ratios and strong-phase differences of the suppressed and favoured $B^\pm$ decays, are also reported

Study of the doubly charmed tetraquark T+cc

Quantum chromodynamics, the theory of the strong force, describes interactions of coloured quarks and gluons and the formation of hadronic matter. Conventional hadronic matter consists of baryons and mesons made of three quarks and quark-antiquark pairs, respectively. Particles with an alternative quark content are known as exotic states. Here a study is reported of an exotic narrow state in the D0D0π+ mass spectrum just below the D*+D0 mass threshold produced in proton-proton collisions collected with the LHCb detector at the Large Hadron Collider. The state is consistent with the ground isoscalar T+cc tetraquark with a quark content of ccu⎯⎯⎯d⎯⎯⎯ and spin-parity quantum numbers JP = 1+. Study of the DD mass spectra disfavours interpretation of the resonance as the isovector state. The decay structure via intermediate off-shell D*+ mesons is consistent with the observed D0π+ mass distribution. To analyse the mass of the resonance and its coupling to the D*D system, a dedicated model is developed under the assumption of an isoscalar axial-vector T+cc state decaying to the D*D channel. Using this model, resonance parameters including the pole position, scattering length, effective range and compositeness are determined to reveal important information about the nature of the T+cc state. In addition, an unexpected dependence of the production rate on track multiplicity is observed

Laboratory diagnostics of syphilis. Modern approaches and perspectives. Part I. Epidemiology. Direct diagnostic methods

Background. Syphilis is a chronic systemic infection caused by T. pallidum. Despite the health authorities’ efforts to prevent the disease prevalence, syphilis continues to be registered in many countries of the world including the Russian Federation causing severe complications like visceral syphilis, congenital syphilis. The disease is often latent that determines the high requirements for laboratory diagnostics. Objective. To highlight some issues of syphilis’ epidemiology and its direct diagnostic methods. Results and discussion. The article provides modern data on syphilis prevalence in the Russian Federation, as well as in Europe and the United States based on official statistics. Most of the review is devoted to the direct research methods used to reveal syphilis: dark-field microscopy, direct immunofluorescence, immunohistochemistry, tissue hybridization, polymerase chain reaction (PCR). Since PCR diagnosis of syphilis are contradictory a number of works reflect in more detail on various aspects of this method usage. Such variants as routine PCR, PCR with reverse transcriptase, nested PCR, real-time PCR, multiplex PCR are covered. Examples of method usage in various biological samples (syphilide material, blood, cerebrospinal fluid, sperm, etc.), its sensitivity and specificity and further prospects are given. The article guides the various specialties who encounter patients with syphilis as well as scientific workers; the possibilities of laboratory diagnosis of syphilis by direct methods, their advantages and disadvantages, and prospects for use are given. © 2021, Media Sphera Publishing Group. All rights reserved

Право и экономика: современные интеграционные процессы

Монография посвящена вопросам интеграции права и экономики. Особый акцент сделан на государственном регулировании предпринимательской деятельности, развитии высокотехнологичной экономики, обеспечении финансово-экономической безопасности, правовом регулировании отдельных видов предпринимательской деятельности, а также рассмотрены новые механизмы обязательственного и договорного права. Монография является результатом научного сотрудничества ученых образовательных организаций, практических работников юридических лиц, а также молодых специалистов предпринимательской сферы. Работа выполнена в рамках исследования научной школы Финансового университета при Правительстве Российской Федерации «Государственное регулирование предпринимательской деятельности». Для юристов, экономистов, представителей органов исполнительной и законодательной власти, а также для широкого круга читателей, интересующихся рассматриваемой тематикой

Право и экономика: современные интеграционные процессы

Монография посвящена вопросам интеграции права и экономики. Особый акцент сделан на государственном регулировании предпринимательской деятельности, развитии высокотехнологичной экономики, обеспечении финансово-экономической безопасности, правовом регулировании отдельных видов предпринимательской деятельности, а также рассмотрены новые механизмы обязательственного и договорного права. Монография является результатом научного сотрудничества ученых образовательных организаций, практических работников юридических лиц, а также молодых специалистов предпринимательской сферы. Работа выполнена в рамках исследования научной школы Финансового университета при Правительстве Российской Федерации «Государственное регулирование предпринимательской деятельности». Для юристов, экономистов, представителей органов исполнительной и законодательной власти, а также для широкого круга читателей, интересующихся рассматриваемой тематикой

Search for the doubly heavy baryons and decaying to and * * We acknowledge support from CERN and from the national agencies: CAPES, CNPq, FAPERJ and FINEP (Brazil); MOST and NSFC (China); CNRS/IN2P3 (France); BMBF, DFG and MPG (Germany); INFN (Italy); NWO (Netherlands); MNiSW and NCN (Poland); MEN/IFA (Romania); MSHE (Russia); MICINN (Spain); SNSF and SER (Switzerland); NASU (Ukraine); STFC (United Kingdom); DOE NP and NSF (USA). We acknowledge the computing resources that are provided by CERN, IN2P3 (France), KIT and DESY (Germany), INFN (Italy), SURF (Netherlands), PIC (Spain), GridPP (United Kingdom), RRCKI and Yandex LLC (Russia), CSCS (Switzerland), IFIN-HH (Romania), CBPF (Brazil), PL-GRID (Poland) and NERSC (USA). We are indebted to the communities behind the multiple open-source software packages on which we depend. Individual groups or members have received support from ARC and ARDC (Australia); AvH Foundation (Germany); EPLANET, Marie Skłodowska-Curie Actions and ERC (European Union); A*MIDEX, ANR, Labex P2IO and OCEVU, and Région Auvergne-Rhône-Alpes (France); Key Research Program of Frontier Sciences of CAS, CAS PIFI, CAS CCEPP, Fundamental Research Funds for the Central Universities, and Sci. Tech. Program of Guangzhou (China); RFBR, RSF and Yandex LLC (Russia); GVA, XuntaGal and GENCAT (Spain); the Leverhulme Trust, the Royal Society and UKRI (United Kingdom)

Abstract: The first search for the doubly heavy baryon and a search for the baryon are performed using collision data collected via the experiment from 2016 to 2018 at a centre-of-mass energy of , corresponding to an integrated luminosity of 5.2 . The baryons are reconstructed via their decays to and . No significant excess is found for invariant masses between 6700 and 7300 , in a rapidity range from 2.0 to 4.5 and a transverse momentum range from 2 to 20 . Upper limits are set on the ratio of the and production cross-section times the branching fraction to ( ) relative to that of the ( ) baryon, for different lifetime hypotheses, at 95% confidence level. The upper limits range from to for the ( ) decay, and from to for the ( ) decay, depending on the considered mass and lifetime of the ( ) baryon