33 research outputs found
The local content of all pure two-qubit states
The (non-)local content in the sense of Elitzur, Popescu, and Rohrlich (EPR2)
[Phys. Lett. A 162, 25 (1992)] is a natural measure for the (non-)locality of
quantum states. Its computation is in general difficult, even in low
dimensions, and is one of the few open questions about pure two-qubit states.
We present a complete solution to this long-lasting problem.Comment: 9 pages, 3 figure
Dynamics of systems with isotropic competing interactions in an external field: a Langevin approach
We study the Langevin dynamics of a ferromagnetic Ginzburg-Landau Hamiltonian
with a competing long-range repulsive term in the presence of an external
magnetic field. The model is analytically solved within the self consistent
Hartree approximation for two different initial conditions: disordered or zero
field cooled (ZFC), and fully magnetized or field cooled (FC). To test the
predictions of the approximation we develop a suitable numerical scheme to
ensure the isotropic nature of the interactions. Both the analytical approach
and the numerical simulations of two-dimensional finite systems confirm a
simple aging scenario at zero temperature and zero field. At zero temperature a
critical field is found below which the initial conditions are relevant
for the long time dynamics of the system. For a logarithmic growth of
modulated domains is found in the numerical simulations but this behavior is
not captured by the analytical approach which predicts a growth law at
Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC
The mesenchymal stroma harbors an important population of cells that possess stem cell-like characteristics including self renewal and differentiation capacities and can be derived from a variety of different sources. These multipotent mesenchymal stem cells (MSC) can be found in nearly all tissues and are mostly located in perivascular niches. MSC have migratory abilities and can secrete protective factors and act as a primary matrix for tissue regeneration during inflammation, tissue injuries and certain cancers
The Young's modulus of fetal preterm and term amniotic membranes
OBJECTIVE: To examine the Young's modulus of the human amniotic membranes, as well as its relationship to gestational age. To determine whether cellular and material-related parameters affect this modulus. STUDY DESIGN: In a prospective study at the Obstetric outpatient clinic of the University Hospital Zurich Young's modulus, thickness and mesenchymal:epithelial cell ratio of amniotic membranes of preterm (N=23) and term (N=40) placentae were examined. Significance (P<0.05) was calculated with the Mann-Whitney two-sample rank sum test and Wilcoxon signed rank test, while correlations were made using the Spearman's correlation. RESULTS: The Young's modulus of preterm amniotic membranes was significantly higher than that of term membranes. It varied within the same amniotic membrane. The thickness of the amnion in both preterm and term membranes did not differ significantly. The thinner the preterm and term amniotic membranes, the higher the Young's modulus was. There was no relation to the mesenchymal:epithelial cell ratio in the amnion. CONCLUSIONS: Preterm amniotic membranes are stiffer than term amniotic membranes. Tentatively, we hypothesise that there may be a correlation between the extracellular matrix components and the elastic properties of the membrane
Enhancing sealing of fetal membrane defects using tissue engineered native amniotic scaffolds in the rabbit model
OBJECTIVE: The purpose of this study was to compare the efficacy of native engineered amniotic scaffolds (AS) and polyesterurethane scaffolds (DegraPol) and document wound healing response when sealing iatrogenic fetal membrane defects in the rabbit model. STUDY DESIGN: Native AS were engineered from freshly harvested membranes of 23 days' gestational age (GA; term = 31-2 d). Acellularity of AS was assessed by histology, light and scanning electron microscopy. Fetal membrane defects were created by 14 gauge-needle puncture at GA 23 days and primarily closed with AS (n = 10) or DegraPol (n = 10) or left unclosed (positive controls; n = 10). Sixty-one sacs served as negative controls. At GA 30 days a second look hysterotomy was performed to assess presence of amniotic fluid (AF) and harvest plugging sites for microscopic evaluation. RESULTS: Engineered AS had a cell-free collagenous fiber network. AF was significantly higher only in the DegraPol group (78%; P < .05) compared to the AF in positive controls (17%). Integration of plugs in the fetal membrane defect was better with AS than DegraPol, with higher reepithelialization rates (AS: 52.5% +/- 6.5%; DegraPol: 11.6% +/- 2.6%; P < .001) and proliferation indices (AS: 0.47 +/- 0.03; DegraPol: 0.28 +/- 0.04; P = .001). In both treatment groups, cell proliferation in the myometrium was increased (P < .05). CONCLUSION: Native AS seal iatrogenic fetal membrane defects better than DegraPol. Within a week, there is abundant reepithelilization and minimal local inflammation. This yields the proof of principle that engineered native, amniotic membrane scaffolds enhance fetal membrane wound healing response