CD3e expression in HTLV-1-infected individuals is associated with proviral load and Tax expression

Financial support: FUNDHERP, CTC, INCTC, FAPESP, CNPq and CAPES

Lanthanopolyoxotungstates in silica nanoparticles: multi-wavelength photoluminescent core/shell materials

We thank Dr Marc Willinger and the RNME (National Electronic Microscopy Network, Portugal) for HRTEM images. Electronic supplementary information (ESI) available: FT-IR and FT-Raman spectra, additional HRTEM images and complementary photoluminescence spectra details, see DOI: 10.1039/b919691a.Photoluminescent lanthanopolyoxotungstate core/shell nanoparticles are prepared by the encapsulation of lanthanide-containing polyoxometalates (POMs) with amorphous silica shells. The preparation of morphological well-defined core/shell nanoparticles is achieved by the hydrolysis of tetraethoxysilane in the presence of POMs using a reverse microemulsion method. The POMs used are decatungstolanthanoates of [Ln(W(5)O(18))(2)](9-) type (Ln(III) = Eu, Gd and Tb). Photoluminescence studies show that there is efficient emission from the POM located inside the SiO(2) shells, through excitation paths that involve O --> Eu/Tb and O --> W ligand-to-metal charge transfer. It is also shown that the excitation of the POM containing europium(III) may be tuned towards longer wavelengths via an antenna effect, by coordination of an organic ligand such as 3-hydroxypicolinate. The POM/SiO(2) nanoparticles form stable suspensions in aqueous solution having the advantage of POM stabilization inside the core and the possibility of further surface grafting of chemical moieties via well known derivatization procedures for silica surfaces. These features together with the possibility of tuning the excitation wavelength by modifying the coordination sphere in the lanthanopolyoxometalate, make this strategy promising to develop a new class of optical bio-tags composed of silica nanobeads with multi-wavelength photoluminescent lanthanopolyoxometalate cores.FCT- POCI/QUI/58887/2004FCT- PTDC/ QUI/67712/2006FCT- SFRH/BD/30137/2006FCT- SFRH/BPD/14954/200

Characterization of Dengue Virus Type 2: New Insights on the 2010 Brazilian Epidemic

Dengue viruses (DENV) serotypes 1, 2, and 3 have been causing yearly outbreaks in Brazil. In this study, we report the re-introduction of DENV2 in the coast of São Paulo State. Partial envelope viral genes were sequenced from eighteen patients with dengue fever during the 2010 epidemic. Phylogenetic analysis showed this strain belongs to the American/Asian genotype and was closely related to the virus that circulated in Rio de Janeiro in 2007 and 2008. The phylogeny also showed no clustering by clinical presentation, suggesting that the disease severity could not be explained by distinct variants or genotypes. The time of the most recent common ancestor of American/Asian genotype and the São Paulo and Rio de Janeiro (SP/RJ) monophyletic cluster was estimated to be around 40 and 10 years, respectively. Since this virus was first identified in Brazil in 2007, we suggest that it was already circulating in the country before causing the first documented outbreak. This is the first description of the 2010 outbreak in the State of São Paulo, Brazil, and should contribute to efforts to control and monitor the spread of DENVs in endemic areas

Dor dentaria e fatores associados em adolescentes brasileiros: a Pesquia Nacional de Saude do Escolar (PeNSE), Brasil, 2009

Abstract published in English and Portuguese English title: Dental pain and associated factors in Brazilian adolescents: the National school-based health survey (PeNSE), Brazil, 2009The aim of this study was to assess the prevalence of dental pain and associated socio-demographic and behavioral factors in Brazilian adolescents, using data from the National School-Based Health Survey (PeNSE), Brazil, 2009. The survey was conducted by the Brazilian Institute of Geography and Statistics (IBGE) and Ministry of Health in students 11 to 17 years of age or older in the 27 State capitals, using a self-administered questionnaire. Analyses included Poisson regression following a hierarchical approach. Prevalence of dental pain in the sample (n = 54,985) in the previous six months was 17.8% (95%CI: 17.5-18.1). Higher prevalence was associated with female gender, age 14 years and over, racial self-identification as black, brown, or indigenous, enrollment in public schools, lower maternal schooling, not living with the mother, history of smoking or drinking, less frequent toothbrushing, and heavy consumption of sweets and soft drinks. Dental pain was thus associated with socio-demographic factors and health-related behaviors. = O objetivo deste estudo foi estimar a prevalência da dor de dente em adolescentes brasileiros e analisar fatores sociodemográficos e comportamentais associados, utilizando os dados da Pesquisa Nacional de Saúde do Escolar (PeNSE) de 2009. A pesquisa foi realizada pelo Instituto Brasileiro de Geografia e Estatística e pelo Ministério da Saúde em escolares com idades entre 11 e 17 anos ou mais, das 27 capitais brasileiras, por meio de questionário autoaplicável. Utilizou-se a análise de regressão de Poisson, segundo um modelo hierárquico de determinação. A prevalência de dor na amostra (n = 54.985) nos últimos seis meses foi de 17,8% (IC95%: 17,5-18,1). Prevalências mais elevadas foram encontradas em mulheres, naqueles com 14 anos ou mais, das raças preta, parda e indígena, de escolas públicas, cujas mães tinham baixa escolaridade, que não moravam com a mãe, que haviam experimentado cigarro e álcool alguma vez na vida, que relataram menor frequência de escovação e maior consumo de guloseimas e refrigerantes. A prevalência de dor foi considerável e associada a aspectos sociodemográficos e de comportamentos relacionados à saúde.Maria do Carmo Matias Freire, Cláudio Rodrigues Leles, Luciana Monteiro Vasconcelos Sardinha, Moacir Paludetto Junior, Deborah Carvalho Malta, Marco A. Pere

Search for narrow resonances in dilepton mass spectra in proton-proton collisions at root s=13 TeV and combination with 8 TeV data

Peer reviewe