9 research outputs found
Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study
- Author
- Liza
- - AP-HP) Bertrand Dousset (H\uf4pital Cochin
- - APHP) Anne Thomin (H\uf4pital Trousseau
- - ASST Rhodense) Carlo Corbellin (Ospedale Di Rho
- - NYU Winthrop Hospital) Amir H Sohail (NYU Langone Health
- - Xarxa Assistencial Universit\ue0ria de Manresa) Pablo Collera Ormazabal (Fundaci\uf3 Althaia
- / Columbia University Medical Center) Miriam Callahan (NewYork-Presbyterian
- 3 University Hospital) Bridget Egan (Tallaght
- 4 Lapolla Pierfrancesco
- 5 Spain: Eduardo E Rubio Susana Henriques (Hospital Garcia de Orta).
- 6 G\uf3mez Marcos
- \u2013 IRCCS Francesca Gaino (Humanitas Clinical and Research Center
- \u2013 Italy) 20089 Rozzano (MI)
- \uc1ngel Hern\ue1ndez Bartolom\ue9 Miguel
- A Aaraj Mahmoud
- A Ayeni Funbi
- A Bass Gary
- A Benson Ruth
- A Bozkurt Mehmet
- A Breen Kerry
- A Breen Kerry
- A Breen Kerry
- A Callcut Rachael
- A Chung Eric
- A Coughlin Patrick
- A de Gheldere Charles
- A De Marchi Joshua
- A Elliott Jessie
- A Fahey Brian
- A Griffiths Ewen
- A Griffiths Ewen
- A Griffiths Ewen
- A Guariglia Claudio
- A Hirji Sameer
- A Khalefa Mohamed
- A Marra (Fondazione Policlinico Universitario Agostino Gemelli) Angelo
- A Nguyen (Frankfurt University Hospital Truong
- A Olson (Duke University Medical Center) Steven
- A Raptis Dimitri
- A Rollett Rebecca
- A Saeed Samerah
- A Salama Hiba
- A Salamah Abdulrauf
- A Schnitzbauer Andreas
- A Schnitzbauer Andreas
- A Singh Aminder
- A Stevens Kent
- A Stylianides Nicholas
- A Thaha Mohamed
- A Vega (12 de Octubre University Hospital) Viviana
- A Vivas Alfredo
- A Zappa Marco
- Abate Emmanuele
- Abdalaziz (Gloucestershire Royal Hospital) Hossam
- Abdelkarim Mostafa
- Abdou Hossam
- Aboelkassem-Ibrahim Ahmad
- Abuown Ala
- Acebes-Garcia Fernando
- Acharya Metesh
- Adamina Michel
- Addae-Boateng Emmanuel
- Adolfo Pisanu (Cagliari University Hospital) Mauro Podda
- Aftab Raiyyan
- AG Moir John
- Agarwal Arnav
- AH Ibrahim Mohamed
- Aitken (Queen Elizabeth University Hospital) Emma
- Al-Azzawi Marwa
- Al-Embideen Somya
- Al-Sukaini Ahmad
- Alakaloko Felix
- Alam (Heartlands Hospital) Ruhina
- Alameer Ehab
- Alderson Derek
- Ali Mohamed Ali (Queen Elizabeth Hospital King's Lynn) Inthekab
- Aliyeva (Acibadem Mehmet Ali Aydinlar University Zumrud
- Aljanadi Firas
- Almasri Murad
- Alonso Poza (Hospital Universitario del Sureste) Alfredo
- Alonso-Ortu\uf1o Paula
- Alser Osaid
- Alser Osaid
- Alser Osaid
- Altintoprak (Sakarya University Faculty of Medicine) Fatih
- Amalina Che Bakri Nur
- Amjad Rabbia
- Anania Gabriele
- and Westminster Hospital NHS FT and Imperial College London) Chelsea
- Andabaka Tatjana
- Andrea Pisani Ceretti (ASST Santi Paolo e Carlo) Nicol\uf2 M Mariani
- Angelou Dimitrios
- Anita Volpe (New York Presbyterian Queens) Stephen Merola
- Annamalai Seethalakshmi
- Annessi Valerio
- Anthoney James
- Anuradha R Bhama (Rush University Medical Center) Alfonso Torquati
- Anwar Sibtain
- Aragon-Chamizo Juan
- Ardito Antonella
- Arigoni Michele
- Armao Teodora
- Arminio (Ospedali Riuniti Azienda Ospedaliera Universitaria Foggia) Armando
- Armstrong Lara
- Asaad Peter
- Ashcroft James
- Ashmore Christopher
- Asqalan Ahmad
- Asti (IRCCS Policlinico San Donato Emanuele
- Aubry Emmanuelle
- Aytac Erman
- Ayuso-Herrera Esther
- Azerbaijan:Elgun Samadov Joana FF Simoes (Chair). 2 Collaborators: (denotes Local Principal Investigator) Algeria: Faraj S Almaadany (\uc9tablissement Hospitalier Sp\ue9cialis\ue9 en Canc\ue9rologie - Centre Pierre-et- Marie-Curie).
- B Avellana Rocio
- B Catton Andrew
- B Fonsi Giovanni
- B Hing Caroline
- B O'Meara Lindsay
- B Schaffer Kathryn
- B Yousuf (Tobruk Medical Center) Farhat
- B\ue0mbina (Fabrizio Spaziani Hospital Fabrizio
- Bailon-Cuadrado (Hospital Universitario R\uedo Hortega) Martin
- Baldi Caterina
- Baldini Edoardo
- Baldo (Ospedale Santa Corona Stefano
- Ballabio Michele
- Baloyiannis Ioannis
- Baltazar Gerard
- Bandiera Alessandro
- Barlow Emma
- Barmasse (Ospedale Regionale Umberto Parini) Roberto
- Barmpagianni Christina
- Baronio (Policlinico San Pietro) Gianluca
- Barra Fabio
- Bartholomew's Hospital) St
- Bartsch Anne-Marie
- Basgaran Amedra
- Basha Amr
- Bashkirova (North Middlesex University Hospital) Varvara
- Bastazza Marco
- BB Sullivan (The Royal London Hospital) Tom
- Beak Philip
- Belcher Elizabeth
- Belgium: Gabrielle H van Ramshorst Sevda Jafarova (Leyla Medical Center).
- Beltr\ue1n de Heredia Juan
- Belvedere Angela
- Ben\uedtez-Linero Inmaculada
- Benjamin Franklin) Campus
- Bergeat Damien
- Bernasconi Matteo
- Bhalla Ashish
- Bhangu Aneel
- Bianco Federica
- Bisagni Pietro
- BJ Borgstein Alexander
- Blake (Southport and Formby District General Hospital) Iain
- Blanco-Colino Ruth
- Blazquez-Martin (Hospital Principe De Asturias) Alma
- Boal Matthew
- Bologna) Ausl
- Bonavina Giulia
- Bonavina Luigi
- Bond-Smith Giles
- Booth (Freeman Hospital) Karen
- Borges Filipe
- Borghi Felice
- Borja De Lacy (Hospital Clinic Barcelona) F
- Bourke Grainne
- Boyle Emily
- Brachini Gioia
- Brain Jessie
- Brar Amanpreet
- Breckles Lisa
- Brendan L Skelly (Altnagelvin Area Hospital) Catherine Rossborough
- Brianza) Carate
- Brixton Genevieve
- Bruzzaniti Placido
- Bueser Teofila
- Burnside Nathan
- C Bosanquet David
- C Brown (Manchester University NHS Foundation Trust Benjamin
- C De Souza Anthony
- C Glasbey James
- C Glasbey James
- C Hopkins James
- C Lauscher Johannes
- C McIntyre Robert
- C Mckay Siobhan
- C Neary Paul
- C Nugent III William
- C Rodriguez-Sanjuan (Marqu\ue9s de Valdecilla University Hospital) Juan
- C Roslani April
- C Tucker Sarah
- C Velmahos (Massachusetts General Hospital) George
- C Winter Stuart
- Caballero Albert
- Cairo University) Mahmoud MA Elfiky (Kasr Alainy Faculty of Medicine
- Calcerrada-Alises Enrique
- Camacho Fern\ue1ndez-Pacheco (Complejo Hospitalario Universitario Insular-Materno Infantil) Borja
- Camarero Enrique
- Campagnaro Tommaso
- Campanelli Michela
- Candiani Massimo
- Cannoletta (Royal Brompton Hospital) Marina
- Cantalejo-Diaz (Hospital Universitario Miguel Servet) Miguel
- Cao Han
- Capizzi Vita
- Carcano (Ospedale di Circolo Giulio
- Carissimi Francesca
- Carlini Massimo
- Carlos Bernal-Sprekelsen Juan
- Carlos Catal\ue1 Bauset (Consorcio Hospital General Universitario) Juan
- Carlucci Michele
- Carmela Giuffrida Maria
- Carmichael Heather
- Carrasco Milagros
- Carrillo Mariana
- Carvello Michele
- Casati Massimiliano
- Castoro Carlo
- Castro Ruiz Carolina
- Catalan Vanesa
- Catriona R Luney (Nuffield Orthopaedic Centre) Benjamin JF Dean
- Cavaleiro Salom\ue9
- Cellerino Paola
- Center Amsterdam) Cancer
- Centinaio (Ospedale Maggiore di Lodi) Giovanna
- Cernei Cristina
- Cervellera Maurizio
- Chakrabortee Sohini
- Chamberlain Stephanie
- Chan Jeffrey
- Chang Grace
- Chaudhry Daoud
- Chebaro Alexandre
- Chen (Jamaica Hospital) David
- Chetty Govind
- Chia (Royal Derby Hospital) Zoe
- Chiappini Ambra
- Chiarugi (Azienda Ospedaliero Universitaria Pisana) Massimo
- Chidambaram Swathikan
- Chiozza Matteo
- Cholewa Hanna
- Chong (Evelina London Children's Hospital) Clara
- Choolani-Bhojwani Ekta
- Christian Cotsoglou (ASST Vimercate) Stefano Granieri
- Chui Karen
- Chung Choyin
- Cirillo Bruno
- Citterio Davide
- Clermidi Pauline
- Coccolini Federico
- Colletti Gaia
- Compagnoni Bruno
- Concepci\uf3n-Mart\uedn Vanesa
- Confalonieri Marco
- Connolly Hannah
- Conso Christel
- Conti Luigi
- Cooper Zara
- Corral Javier
- Costa Marta
- Costanzi Andrea
- Cox Daniel
- Cozza Valerio
- CR Wormald Justin
- Croatia: Jakov Mihanovic Nicolas Duchateau (Heilig Hart Ziekenhuis Lier).
- CS Clough Ethan
- Cuming Tamzin
- Cuneo)
- Curtis Miles
- Cuschieri Joseph
- D Baron Ryan
- D Bosch Karen
- D Brown Oliver
- D Bueno-Ca\uf1ones Alejandro
- D Cato Liam
- D Drake Thomas
- D Jenkinson Michael
- D Jenkinson Michael
- D Liyanage Aloka S
- D Pinkney Thomas
- D Rajgor Amarkumar
- D Stewart Grant
- D Tebala Giovanni
- D'Agruma Michele
- D'Andrea Giancarlo
- D\uedaz P\ue9rez David
- D\uedaz-Garc\ueda (Hospital Universitario Nuestra Se\uf1ora de Candelaria) Alberto
- Da Roit Anna
- da Saliceto\u201d Patrizio Capelli (Ospedale \u201cG.
- Dare Oliver
- Darko Ebenezer
- Data Monitoring and Ethics Committee: Deborah S Keller H. Hunt Batjer (University of Texas Southwestern).
- Day Andrew
- De Andr\ue9s-Asenjo Beatriz
- de Medicina Facultad
- De Miguel-Ardevines Maria-Carmen
- De Nardi Paola
- De Simone Veronica
- De Toma Giorgio
- Deepti Sinha (University College London Hospital) Nicholas Kalavrezos
- Dehal (Kaiser Permanente Panorama City Medical Center) Ahmed
- Dehart Dustin
- Del Giudice Roberto
- Delgado-Oliver Eduardo
- Denmark: Henry G Smith Bernarda Bakmaz (Zadar General Hospital).
- Denning Max
- Desai Anant
- Desender (Ghent University Hospital) Liesbeth
- Dester (ASST Valcamonica Ospedale di Esine) Sara
- Di Candido Francesca
- Di Chiara Francesco
- Di Franco Gregorio
- Di Giuseppe (Ente Ospedaliero Cantonale del Canton Ticino) Matteo
- Di Saverio Salomone
- Di Saverio Salomone
- Di Saverio Salomone
- Di Saverio Salomone
- Diaz-Pe\uf1a Patricia
- Dieguez Fernandez Beatriz
- Dissemination Committee: Michel Adamina Aneel Bhangu.
- Dolores Del Toro M
- Domodossola
- Doussot Alexandre
- Duff Sarah
- Dunning Joel
- Dunstan Matt
- Duque-Mallen Victoria
- Dziakova Jana
- E Canova Michaela
- e Carle Hospital Chiara Peluso (Santa Croce
- e Carlo ASST Santi Paolo
- E Dawson Brett
- E Dickson Kathryn
- E Hudson Victoria
- E Jenny (Johns Hopkins Hospital) Hillary
- E Lewis Sophia
- E Nita George
- e Oftalmico) Giulio Iacob (Ospedale Fatebenefratelli
- E P\ue9rez-S\ue1nchez Luis
- E Rice Henry
- E Ssentongo Anna
- e Universit\ue1rio de Coimbra) Ana C Almeida (Centro Hospitalar
- E Xyda Souzana
- Edward Fitzgerald J
- EF Abbott Tom
- EF Abbott Tom
- Egan Richard
- Egypt: Mohamed El Kassas University of Copenhagen).
- El Youzouri Hanan
- El-Ali (Queen's Hospital Abess
- Elaine YL Leung (The Pan Birmingham Gynaecological Cancer Centre) Sudha Sundar
- Elfeki Hossam
- Elhadi Muhammed
- Eljareh (Aljalaa Hospital) Mohammed
- Elkadi Hannah
- Elkady Ramy
- Elkhafeefi Fatimah
- Elmore Ugo
- Elmoslemany (The Walton Centre NHS Foundation Trust) Tarek
- EM Bouhuwaish Ahmad
- EM Brathwaite Collin
- Emmerson (North Manchester General Hospital) Oliver
- Enemosah Ibrahim
- English Camilla
- English William
- Ereidge Simon
- Escartin Jorge
- Estaire-Gomez Mercedes
- EuroSurg
- Evans (Queen Elizabeth the Queen Mother Hospital Margate) Jessica
- Exley Rebecca
- F Bath Michael
- F Cunha Miguel
- F Cunha Miguel
- F Davis Niall
- F Ridgway Paul
- Fabbri Nicol\uf3
- Falco Giuseppe
- Familiari Pietro
- Fancellu (Cliniche San Pietro Alessandro
- Fanjul G\uf3mez Mar\ueda
- Farik Shebani
- Farr\ue9 Font Roser
- Farrell Tony
- Fehervari Matyas
- Fell Adam
- Fern\ue1ndez- Mart\uednez Mar\ueda
- Fern\ue1ndez-Gomez Cruzado (Hospital Urduliz) Laura
- Fern\ue1ndez-Mar\uedn Reyes
- Fernandez-Camu\uf1as Angel
- Ferrara)
- Ferrara Francesco
- Ferrari Guglielmo
- Ferrero Simone
- FF Simoes Joana
- FF Simoes Joana
- Findlay Laura
- Fiore Marco
- Fiore Marco
- Fiori Enrico
- FJ Dunne Declan
- Flatman Michael
- Flindall Ian
- Fontana (Vittorio Emanuele Tommaso
- Ford (The Robert Jones and Agnes Hunt Orthopaedic Hospital) David
- Ford Samuel
- Forlani Stefano
- Fr\ue9d\ue9ric Bretagnol (H\uf4pital Louis-Mourier - GHU AP-HP. Nord - Universit\ue9 de Paris) David Moszkowicz
- France: Zaher Lakkis Mohamed Sherief (MISR Cancer Center/MISR International Hospital).
- Francisco de Vitoria Universidad
- Francone Elisa
- Frattaruolo Colomba
- Frio (Institute of Neurological Sciences of Bologna Federico
- Frosinone)
- G Aoun Salah
- G Barranquero Alberto
- G Blazer III Dan
- G Collins Chris
- G Edwards John
- G Edwards John
- G Morton Dion
- G Povey Meical
- G Velopulos Catherine
- G Wade Ryckie
- Gabriel Kinnaman (IU Health Methodist Hospital) Ashley D Meagher
- Gagliano Annalisa
- Gagliardi Filippo
- Gahunia Sukhpreet
- Gala Tanzeela
- Galfrascoli Elisa
- Galimberti Luca
- Galindo Jara (Hospital Universitario de Torrej\uf3n Pablo
- Gallagher Phoebe
- Galleano Raffaele
- Gallo Gaetano
- Gallo Gaetano
- Gallo Gaetano
- Galv\ue1n-P\ue9rez Armando
- Gamal Amira Ibrahim Sallam
- Gammeri Emanuele
- Ganau Mario
- Garc\ue9s-Garc\ueda Ra\ufal
- Garcia Fernandez Andres
- Garcia-Conde Delgado Maria
- Garulli (Ospedale Infermi di Rimini) Gianluca
- Gascon-Ferrer Isabel
- Gattolin (Regina Montis Regalis Hospital Andrea
- Gaujoux Sebastien
- Gentilli Sergio
- Georgiades Fanourios
- Germany: Carsten Kamphues Didier Ollat (Institut Mutualiste Montsouris).
- Gerogiannis (Kingston Hospital NHS Foundation Trust) Ioannis
- Ghanbari (Homerton University Hospital) Amir
- Ghosh Dhruv
- Giacometti Marco
- Giblin Anna-Victoria
- Gilbert (Surrey and Sussex Healthcare NHS Trust) Catherine
- Gim\ue9nez Clara
- Giorgakis Emmanouil
- Gipponi Manuel
- Glen Paul
- GlobalPaedSurg GlobalSurg
- Goatly Giles
- Gobatti (San Carlo Borromeo Hospital Davide
- Godbole Chintamani
- Gohil Kajal
- Gomez-Rosado Juan-Carlos
- Gonullu Emre
- Gonzalez-De Miguel Melania
- Gonzalez-Gonzalez Enrique
- Gordini Luca
- Gracia Isabel
- Gracia-Roche Carlos
- Greece: Konstantinos Bouchagier Markus W L\uf6ffler (University Hospital Tu\u308bingen).
- Green Susanna
- Grivon Manuela
- Grove (Department of Colorectal Surgery Thomas
- Guaglio Marcello
- Guaitoli (Perrino) Eleonora
- Guglielmi Alfredo
- Guha Soumya
- Gustavino (Unit of Obstetrics and Gynecology IRCCS Ospedale Policlinico San Martino Genoa) Claudio
- Guti\ue9rrez Samaniego Mar\ueda
- H Babu Bheemanakone
- H Chowdhury Abeed
- H Davidson Giana
- H Davidson Giana
- H Davidson Giana
- H Elfallal Ahmed
- H Emile Sameh
- H Kirmani Bilal
- H Liu Helen
- H Murphy Suzanne
- H van Ramshorst Gabrielle
- H\uf6lzle Frank
- Habeeb Amir
- Hagger Robert
- Hakmi Hazim
- Halkias Constantine
- Halkias Constantine
- Hampton (Rotherham District General Hospital) Matthew
- Handa Siddhartha
- Haq Iram
- Harky (Liverpool Heart and Chest Hospital) Amer
- Harries (Morriston Hospital Rhiannon
- Harrison Joseph
- Hasan Raashad
- Hawari Mohammad
- Hawkin Paul
- Hebblethwaite Bethany
- Helier University Hospitals NHS Trust) St
- Heritage Emily
- Hernandez Garcia Miguel
- Hernandez-Juara Pilar
- Herrero-Lopez Maria
- Hervieux Erik
- Heyd Bruno
- Higgs Simon
- Hitchman (Hull University Teaching Hospitals NHS Trust) Louise
- Ho Beatrice
- Hogan Aisling
- Hospital of Varese University
- Hospital Universitario del Henares) Miguel Angel Garcia-Ure\uf1a (Universidad Francisco de Vitoria
- Hospital) Atakent
- Hospital) Wythenshawe
- Hossain Tanvir
- Houston Roy
- Hurt Libor
- HV Byrne Matthew
- i Pujol) Alba Zarate (Hospital Germans Trias
- I Roxo (Brigham and Women's Hospital) Vanessa
- I van Berge Henegouwen (Amsterdam UMC Mark
- I Alessandro Di Bartolomeo (Policlinico Umberto
- Iannone Immacolata
- Ibrahim Sherif
- Iovino Domenico
- Ireland: Arnold DK Hill Paraskevi Tourountzi (Kavala General Hospital).
- Isik Arda
- Israel: Oded Zmora Thomas M Aherne (Galway University Hospital).
- Italy: Maurizio Zizzo Nadav Kugler (Shamir Medical Center).
- J Abbott Sarah
- J Baker Olivia
- J Baldwin Alexander
- J Beamish Andrew
- J Carlos William
- J Caruana Edward
- J Caruana Edward
- J Davies Emma
- J Diaz Jose
- J Doe Matthew
- J Eardley Nicola
- J Fern\ue1ndez Antonio
- J G\uf3mez D\uedaz Carlos
- J Hainsworth Alison
- J Hall Bria
- J Holme Thomas
- J Hutchinson Peter
- J Hutchinson Peter
- J Kalkwarf Kyle
- J Lin Daniel
- J Lowery Aoife
- J McCluney Simon
- J Mehigan Brian
- J Mills Sarah
- J Pachl (Birmingham Children's Hospital) Max
- J Rogers Luke
- J Ryan \uc9anna
- J Scurrah Rachel
- J Shackcloth Michael
- J Smart Neil
- J Steinkamp Pieter
- J Tejero-Pintor Francisco
- J Thomas Amy
- J Torres Antonio
- J Warren Oliver
- J Warren Oliver
- J Williams Katherine
- James RW Hall (Stepping Hill Hospital) Claire Hall
- James's Hospital) Conor P Barry (St.
- Jamil Tahir
- Jayaraju (University Hospital of Wales) Ullas
- Jenner Edward
- JG Chase Thomas
- Jha Shane Lester (James Cook University Hospital) Madan
- Jimenez-Higuera Elisa
- Jimeno Jaime
- JM Dunne Naomi
- JM Ferguson Henry
- Jo\ue3o Lima Maria
- Johnstone Jack
- Jones Mark
- Jordan: Mahmoud Al-Masri Gela).
- JS Wall Joshua
- Judkins Nicholas
- JW Wilkin Richard
- K Abou Chaar Mohamad
- K Ambler Graeme
- K Bankhead-Kendall Brittany
- K Bankhead-Kendall Brittany
- K Bankhead-Kendall Brittany
- K Brown Allison
- K Fusai Giuseppe
- K Gill Charn
- K Kamarajah Sivesh
- K Patel Panna
- K Ubhi Harmony
- K Weerasinghe Chamindri
- K\uf6nigsrainer Alfred
- Kalidindi Venugopala
- Kamal Mona
- Kang Chong
- Kara Yasin
- Karam Edward
- Karim Ahmed
- Kashora Florence
- KC Jonker (University Medical Center Groningen (University of Groningen) Pascal
- Kearney (Beaumont Hospital) David
- Khajuria Apoorva
- Khan Azam
- Khan Umul
- Khatri Chetan
- Kinross James
- Kler Aaron
- Klimopoulos (Evangelismos General Hospital) Serafeim
- Kocata\u15f (Kanuni Sultan Suleyman Training and Research Hospital) Ali
- Kolias Angelos
- Kolias Angelos
- Kontovounisios Christos
- Kourdouli (Leicester Royal Infirmary) Amar
- Krishnan Emily
- Kristinsson Sverrir
- Kruijff Schelto
- KS Viswanath Yirupaiahgari
- Kudsk-Iversen S\uf8ren
- Kufeji Dorothy
- Kulkarni Rugved
- Kurihara Hayato
- L Biffl Walter
- L Coleman Natasha
- L Collins Michelle
- L Engel (Temple University Hospital) Jamie
- L Fowler Amy
- L Garcia Galocha Jose
- L Hughes Jane
- L J\uf6nsson (Bispebjerg Hospital Maria
- L Labib Peter
- L Marsh (Scripps Memorial Hospital) Christopher
- L McKevitt Kevin
- L Osorio Alexander
- L Romera Jose
- L Serevina Olivia
- L Venn Mary
- L Venn Mary
- L Venn Mary
- L Wright Franklin
- L Young Alastair
- L\ue1zaro Andr\ue9
- La Torre Filippo
- Laface (Ospedale Vittorio Emanuele III Letizia
- Lami Mariam
- Landaluce-Olavarria Aitor
- Laura Hansen 9
- Lawani Ismail
- Lawday (Southmead Hospital) Samuel
- Lawday Samuel
- Le Roy Bertrand
- Lecco) Asst
- Lecolle Katia
- Lederhuber Hans
- Lederhuber Hans
- Leeds)
- Leicester)
- Leventoglu Sezai
- Li Elizabeth
- Li Elizabeth
- Li Zoe
- Libya: Ghadah Z Alkadeeki Hani Al-Najjar (King Hussein Cancer Center).
- Liew Ignatius
- Ligure (SV) Pietra
- Lima Buarque Igor
- Lisi Giorgio
- Lizzi Vincenzo
- Lo Terence
- Lombardia) Regione
- Lomiento Daniele
- Longhi Marco
- Lopez Antonanzas (Hospital Clinico San Carlos Leyre
- Losada Ruiz Manuel
- Lostis Emilie
- Lostoridis Eftychios
- Loubani Mahmoud
- Lowy- Benoliel Alejandro
- Lucianetti (Papa Giovanni XXIII Hospital) Alessandro
- Luigi MP Marino Cosentino (PO San Filippo Neri - ASL ROMA 1) Andrea Sagnotta
- luis Blas Laina Juan
- Luke Evans (Norfolk and Norwich University Hospital) Mina MG Youssef
- Luke Louis
- Lunevicius Raimundas
- Luraghi Marco
- Lye George
- M Alrahawy (Menofiya University Hospital) Mahmoud
- M Andreani Stefano
- M Ashoush Fouad
- M Bajomo Oreoluwa
- M Blundell Chris
- M Cicerchia Pierfranco
- M Connolly Tara
- M Diez-Alonso Manuel
- M Dur\ue1n-Mu\uf1oz-Cruzado (Hospital Universitario Virgen del Rocio) Virginia
- M Emslie Katy
- M Harrison Ewen
- M Holbrook Charlotte
- M Isolani Simone
- M Keatley James
- M Leite-Moreira Andr\ue9
- M Mithany Reda H
- M Mohan Helen
- M Mohan Helen
- M Monteiro Joana
- M Morgom (Tripoli Central Hospital) Marwa
- M Muguerza Jose
- M Nunes Quentin
- M Nygaard Rachel
- M Omar Aneel Bhangu Omar
- M Philp Matthew
- M Pollok Joerg
- M Rooney Siobhan
- M Sampietro Gianluca
- M Sewards Joseph
- M Tang Alethea
- M Trout Isobel
- M Walters (Harborview Medical Center Andrew
- MA Kaafarani Haytham
- MA Kaafarani Haytham
- MA Kaafarani Haytham
- Maarten van Heinsbergen (VieCuri Medisch Centrum) Joop Konsten
- Mabrouk Islam
- Macchi Alberto
- MacDonald Luisa
- Machairas (Royal Free Hospital) Nikolaos
- Madonini Marco
- Madrid)
- Madrid)
- Magalh\ue3es Maia Mariana
- Magne Augestad Knut
- Magowan Drew
- Maha H Haqqani (Boston Medical Center) Frederick T Drake
- Maisonneuve Emeline
- Majkowska Agata
- Majkowski (Northern General Hospital Lawrence
- Mak (Queen Elizabeth Hospital Birmingham) Jason
- Malabarba Stefano
- Malerba Michele
- Maninder Kalkat 7
- Mannan Syed
- Manson Joanna
- Mansuri Ahmer
- Mantoglu (Sakarya University Research and Educational Hospital) Baris
- Manu Nichola
- Manzoni 56 Via
- Maqsood Afnan
- Marano Alessandra
- Marchbank Adrian
- Marcos-Santos Pablo
- Marinos Kouris (Buckinghamshire Healthcare NHS Trust) Spyros
- Marqueta De Salas Maria
- Marrano Enrico
- Mart\uedn-Rom\ue1n Lorena
- Mart\uednez P\ue9rez Carolina
- Mart\uednez-dePaz Fernando
- Martel Lozano Saida
- Martin (St Mary's Hospital) Guy
- Martin Emmeline
- Martin Janet
- Martin-Albo Lorena
- Martine Uittenbogaart (M\ue1xima Medical Center) Wouter KG Leclercq
- Martinelli Fabio
- Martinez-German Antonio
- Martinez-Pinedo Carlos
- Martins Ricardo
- Marwan Hisham
- Marzi Federica
- MAS Baig Mirza
- Mateos-Sierra (Hospital General Universitario Gregorio Mara\uf1\uf3n) Olga
- Mater Studiorum University of Bologna) Alma
- Mathieu (CHU Besan\ue7on) Pierre
- Matute-Najarro Maria-Soledad
- Maw Andrew
- Mazingi Dennis
- Mazzaferro (Fondazione IRCCS Istituto Nazionale dei Tumori Vincenzo
- McCanny (Antrim Area Hospital) Andrew
- McKenzie Katherine
- McLarty (Northumbria NHS Hospital Trust) Nicola
- McPherson Iain
- Medina Esther
- Mediratta Saniya
- Medone Marzia
- Mehra (Guy's and St Thomas\u2019 NHS Foundation Trust) Gautam
- Mele Simone
- Melero-Cort\ue9s Lidia
- Melody Baeza (Morales Meseguer University Hospital) Jos\ue9 Aguilar
- Mendon\ue7a Ata\uedde Gomes Gustavo
- Mendoza-Moreno Fernando
- Meneghini Simona
- Merate
- Mercante Giuseppe
- Merdrignac (Rennes University Hospital) Aude
- Metallidis Symeon
- Michel (Pinderfields Hospital) Martin
- Migliore Marco
- Milan)
- Milan)
- Milan)
- Miller Douglas
- Minaya- Bravo Ana
- Minaya-Bravo Ana
- Minaya-Bravo Ana
- Minaya-Bravo Ana
- Mingoli Andrea
- Minto Gary
- Mirabella Antonello
- Misra Nikhil
- Mitrasinovic Stefan
- Miu Victor
- Moawad (Royal Victoria Hospital) Nader
- Mochet Sylvie
- Modabber Ali
- Mohammad Adam
- Mohan Midhun
- Moliner-S\ue1nchez Carmen
- Mondov\uec)
- Mongelli Francesco
- Monteleone (Ospedale San Leopoldo Mandic Michela
- Montuori Mauro
- Moore Rachel
- Mora-Guzm\ue1n (Hospital Santa B\ue1rbara) Ismael
- Morales Dieter
- Morales Xavier
- Morelli Luca
- Morelli Lucia
- Morgan Richard
- Morris Chris
- Mortini Pietro
- Mosca Angelo
- Moszkowicz David
- Moszkowicz David
- Motter Dema
- Moug Susan
- Mukherjee Samrat
- Munoz Rivas Ana
- Murcia)
- N Bence Matthew
- N Hopkinson David
- N Mashbari Hassan
- N Mashbari Hassan
- N Mashbari Hassan
- N Naumann David
- N Rao Jagan
- N Townshend David
- N\ufa\uf1ez Jordi
- Najdy Manhal
- Nakas (Glenfield Hospital Apostolos
- Namazov Ilgar
- Naredla Pradyumna
- Nasef Emmhamed
- Nassa Heeam
- Nath Rahul
- Navarro-S\ue1nchez Antonio
- Nazarian (Bupa Cromwell Hospital) Scarlet
- Neal Bhutiani (University of Louisville Hospital and Norton Hospital) Robert CG Martin
- Negri Giampiero
- Nehra Deepika
- Neil-Dwyer Jason
- Nepogodiev Dmitri
- Nepogodiev Dmitri
- Nepogodiev Dmitri
- Neri Jacopo
- Netherlands: Suzanne S Gisbertz Mustafa R Bulugma (Zawia Teaching Hospital). Mexico: Fernando Cordera (ABC Medical Center).
- Newton (Manchester Royal Infirmary) Katy
- Nikaj (Azienda Ospedaliero Universitaria Maggiore della Carit\ue0 Herald
- Niquen Milagros
- Nobile (Azienda Ospedaliera Universitaria Integrata di Verona) Sara
- Nogueiro Jorge
- Nogues Pevidal (Royo Villanova) Ana
- Novara)
- Ntirenganya Faustin
- Nugent Michael
- O Ademuyiwa Adesoji
- O Kavanagh Dara
- O Larkin John
- Oca\uf1a Juan
- of Amsterdam University
- of Ferrara) University
- of Insubria University
- of Milan) University
- of Surgeons in Training (ASiT) Association
- of Surgery) Department
- of Washington) University
- Okafor Barbara U.
- Okechukwu Valentine
- Oliva-Mompean (Hospital Universitario Virgen Macarena) Fernando
- Oliveira Ana
- OM Abdalla Mutwakil
- Omar M Omar
- OO Ayorinde John
- Osagie-Clouard (Epsom &
- Osman (Walsall Manor Hospital) Khabab
- Ottolina Jessica
- Ourieff (Mount Sinai Hospital) Jared
- Outani Oumaima
- Oyewole Bankole
- P Arnaud Alexis
- P Arnaud Alexis
- P Arnaud Alexis
- P Baker Markus
- P Belgaumkar Ajay
- P Boddy Alexander
- P Duffy (Nottingham City Hospital) John
- P Evans Jonathan
- P Hazelton Joshua
- P Jones Andrew
- P Jones Robert
- P Joyce Doireann
- P Kisiel Aaron
- P Pezzuto Anna
- P Singh Rabindra
- P\ue9rez-Gonz\ue1lez Marta
- P\ue9rez-Saborido Baltasar
- Pacheco-Sanchez David
- Padilla-Valverde (Hospital General Universitario De Ciudad Real) David
- Pai (Hammersmith Hospital) Madhava
- Paiella Salvatore
- Paisley (Brighton and Sussex NHS Trust Samuel
- Palermo)
- Palini Gianmarco
- Palmeri Matteo
- Parente Alessandro
- Parlanti Daniele
- Parmar Chetan
- Pascual Angela
- Pata Francesco
- Pata Francesco
- Patel Mahul
- Pathak Abhijit
- Patil Sangram
- Pattyn Piet
- Peckham- Cooper Adam
- Pedram Panahi (University Hospitals Plymouth NHS Trust) Mariam Rela
- Pedrazzani Corrado
- Pellino Gianluca
- Pereira Andr\ue9
- Pereira-Neves Ant\uf3nio
- Perez-Diaz Md
- Perivoliotis (General University Hospital of Larissa) Konstantinos
- Perkins Clare
- Perotto (CHU Saint Etienne) Ornella
- Perra Teresa
- Petrone Patrizio
- Phenix George
- Piacenza)
- Picazo Sara
- Picon-Rodriguez Rafael
- Piloni Martina
- Pingarr\uf3n-Mart\uedn Lorena
- Pinotti Enrico
- Pizzini Paolo
- PM de Vries Jean-Paul
- Pockney Peter
- Podolsky Dina
- Poggioli Gilberto
- Pompili Cecilia
- Pontari Michael
- Porcu Alberto
- Portugal: Hugo Santos-Sousa Pakistan: Mariyah Anwer (Jinnah postgraduate medical center).
- Potter (Royal Bournemouth Hospital) Ryan
- Price Claire
- Prita Daliya 8
- Pruvot (Lille University Hospital) Fran\ue7ois-Ren\ue9
- PTSurg ItSURG
- Pujol-Muncunill Roger
- Puppo Andrea
- Q Mehdi (University of Texas Medical Branch) Mohammad
- Quante Markus
- Quintana-Villamandos Bego\uf1a
- Qureshi Ali
- R Burke Joshua
- R Davidson Brian
- R Dixon Jan
- R Fretwell Kenneth
- R Gujjuri Rohan
- R Gujjuri Rohan
- R Kowal Mikolaj
- R O\u2019Neill John
- R Sarma Diwakar
- R Spalding Duncan
- R Springford Laurie
- Rachel Baumber (Royal National Orthopaedic Hospital) James T Parry
- Radenkovic Dejan
- Rahman Saad (Medway Maritime Hospital) Abdel
- Rakvin Ivan
- Ramallo-Sol\ueds Irene
- Ramcharan Sean
- Ramos Diego
- Ramos-Bonilla Antonio
- Ramos-De la Medina Antonio
- Ramzi Joussi
- Rathinam Sridhar
- Rausa Emanuele
- Ravaioli Matteo
- Ravindran Sharanya
- Raymond (Royal Lancaster Infirmary) Thomas
- Razik Aisha
- Redfern (Furness General Hospital) Jennifer
- Reguera-Rosal Julio
- Rey-Biel Juan
- Rey-Valcarcel Cristina
- RG Sheel Andrea
- Ribolla Marta
- Richards Tomos
- Richmond (University of Maryland Medical Center) Michael
- Righini (Ospedale del Delta Erminio
- Rio-Gomez Javier
- Riuniti Villa Sofia-Cervello Ospedali
- Riyat Harjoat
- Rizvi Sana
- Roberts Keith
- Roberts Matthew
- Robertson (University Hospitals Coventry and Warwickshire) Stuart
- Robertson (University of Arkansas for Medical Sciences) Ronald
- Robin-Valle Alvaro
- Rochon Melissa
- Rojo Mikel
- Rolli Luigi
- Romano Silvio
- Rome)
- Romford)
- Ross Elizabeth
- Ross Howard
- Rottoli Matteo
- Royal Hospital) Princess
- Ruiz (Hospital General Universitario Reina Sof\ueda Miguel
- Ruiz- Grande Fernando
- Ruiz-Martin (Rey Juan Carlos University Hospital) Irene
- Ruiz-Soriano (Hospital Cl\uednico Universitario de Valladolid) Mar\ueda
- Ruzzenente Andrea
- Ryska Ondrej
- S Abdelaal (Alexandria Main University Hospital) Ahmed
- S Al Maadany Faraj
- S Faria Carlos
- S Hammond John
- S Hossain Fahad
- S Jeyaretna Deva
- S Jones Conor
- S Khan (Queen Alexandra Hospital) Jim
- S Moura Francisco
- S Ng-Kamstra Joshua
- S Sica Giuseppe
- S Tamimy Muhammad
- S Wadley Martin
- S\ue1nchez- Arteaga Alejandro
- SA Taher Ahmed
- Saez Carlos
- Sahnan Kapil
- Sahni Arun
- Salim Ali
- Salvia Roberto
- Sammarco Giuseppe
- Sampaio-Alves Mafalda
- San Miguel-Mendez Carlos
- Sanchez del Pueblo Cristina
- Sanchez-Fuentes Maria-Nieves
- Sanchez-Pelaez Daniel
- Sanchez-Perez Coral
- Sanchez-Rubio Maria
- Sancho-Muriel Jorge
- Sanchon Fructuoso Lorena
- Sanders Julie
- Santero-Ramirez Maria-Pilar
- Santora Thomas
- Santoro Antonio
- Santos Irene
- Sapienza Paolo
- Sartarelli (Sant\u2019Orsola Hospital Lodovico
- Sarveswaran Janahan
- Sasia Diego
- Sassari) A. O. U.
- Saudemont Alain
- Saudi-Moro Sef
- Saxena Dolly
- Saxena Shobhit
- Sayasneh Ahmad
- Scalabre Aurelien
- Schache Andrew
- Schiavina Riccardo
- Schineis (Charit\ue9 University Medicine Christian
- Schreckenbach Teresa
- Scorza Antonella
- Scott Lucy
- Seegert (ProMedica Toledo Hospital) Sara
- Seguin-Givelet Agathe
- Senent-Boza Ana
- Serrano Gonz\ue1lez Javier
- Sette Laghi Asst
- Seymour Keith
- Shabana Amanda
- Shah (The Whittington Hospital) Sujay
- Shah Jigar
- Shah Karishma
- Shah Preena
- Shakir Taner
- Shalaby (Mansoura University Hospital) Mostafa
- Shankar (Oxford University Hospitals NHS Foundation Trust Sushma
- Shaw Richard
- Sheffield)
- Shehata Sameh
- Shelley Hwang E.
- Shen Ban Vin
- Shenfine Amy
- Sheridan Kelda
- Sherief Ahmed
- Sherif Mohamed
- Shinkwin Michael
- Shu Sebastian
- Siaw-Acheampong Kwabena
- Sileri (San Raffaele Scientific Institute Pierpaolo
- Singh Abhinav
- Singh Shailendra
- Sinha Sanjay
- Siragusa (Policlinico Tor Vergata Hospital Leandro
- Sivaprakasam Rajesh
- Sivayoganathan Sriharan
- SJ Ledesma Frances
- Smillie Robert
- Smith (Countess of Chester Hospital) Claire
- Smith Andrew
- Smith Christopher
- Sochorova (Royal Liverpool University Hospital) Dana
- Society of Coloproctology (ESCP) European
- Society of Colorectal Surgery (SICCR) Italian
- Soggiu Fiammetta
- Sohrabi (St Bartholomew's Hospital) Catrin
- Sohrabi (Whipps Cross University Hospital) Catrin
- Sohrabi Catrin
- Solari (Royal Gwent Hospital) Francesca
- Solli Piergiorgio
- Soreide Kjetil
- Soto Montesinos Cristina
- SpainSurg
- Spinelli Antonino
- Spinelli Antonino
- Spoletini (Sant'Eugenio Hospital) Domenico
- Spriano Giuseppe
- Sravanam Sanskrithi
- Ssentongo (Pennsylvania State University) Paddy
- Stanger Sophie
- Stavroulias Dionisios
- Steel (Sunderland Royal Hospital) Ben
- Stella Marco
- Stewart Robbie
- Stringer Sally
- Sudan: Osman M Ali Elima P Cagigal- Ortega (Hospital Universitario Severo Ochoa).
- Sulen Nina
- Sundar Sudha
- Sundhu (Aintree University Hospital) Matthew
- Surgical Research Collaborative (ISRC) Irish
- Suri (University of California Davis Health Avni
- Swansea)
- Switzerland: Dimitri Christoforidis Ali A Ali karar (Al-rajhi).
- Syed Arooj
- Szatmary Peter
- T Colonna Emily
- T Enjuto Diego
- T Montella (Azienda Unit\ue0 Sanitaria Locale-IRCCS di Reggio Emilia) Maria
- TA Neely David
- Tabiri Stephen
- Tadross Daniel
- Taglietti Lucio
- Tansey (Princess Alexandra Hospital) Rosamond
- Tartaglia Dario
- Tawheed (Endemic Medicine Department Ahmed
- Tayeh Salim
- Testa Valentina
- Tewari Nilanjana
- Thoenissen Philipp
- Thomas (Worcestershire Acute Hospitals NHS Trust) Kane
- Thrush Jessica
- Tierney Sean
- Tiwari Abhinav
- Tobias Teles (Hospital de Cascais - Dr. Jos\ue9 de Almeida) Pedro A Serralheiro
- Toledo Enrique
- Tonini Valeria
- Torkington Jared
- Torzilli Guido
- Totty Joshua
- Tousidonis Manuel
- Townend Philip
- Townsend Catherine
- Trompeter (St George's Hospital) Alex
- Trotta Francesco
- Truant St\ue9phanie
- Trujillo-D\uedaz Jeancarlos
- Tsoulfas George
- Tsoulfas Georgios
- Turco Celia
- Turkey: Volkan Ozben Georgios Peros (Kantonsspital Winterthur).
- Turrado- Rodriguez Victor
- Turri Giulia
- Tustin (Cumberland Infirmary) Harry
- Tyler Jayne
- Tzedakis Stylianos
- Tzovaras George
- Ullah Ramzan
- Unit\ue0 Sanitaria Locale di Ferrara Azienda
- United Kingdom: Richard J Davies Alp Yildiz (Yildirim Beyazit University Yenimahalle Training and Research Hospital).
- United States: John RT Monson (AdventHealth Orlando) Lavinia Onos (York Teaching Hospitals NHS Trust).
- University Hospitals NHS Trust) Nottingham
- University of Rome) Sapienza
- University) Goethe
- University) Helwan
- Urban (University of Colorado Hospital) Shane
- Urbani (Azienda Ospedaliero Universitaria San'Anna Alessia
- Usai Antonella
- V Bhavaraju Avi
- V Comini Lara
- V Feo Carlo
- V Marino Marco
- V Shaw Abigail
- V\ue1zquez- Fern\ue1ndez Andrea
- Vaccarella (Azienda Ospedaliera Gianpaolo
- Valdes- Hernandez Javier
- Valsecchi Luca
- Vashisht Rajiv
- VCO) Asl
- Venkatesan (Glan Clwyd Hospital) Gowtham
- Vera-Mansilla Cristina
- Vergari (Ospedali Riuniti di Ancona) Roberto
- Vescio (University 'Magna Graecia' of Catanzaro) Giuseppina
- Vidya Raghavan
- Vieira (Centro Hospital Universit\ue1rio S\ue3oJo\ue3o) Paula
- Vijay Vardhini
- Vimalachandran Dale
- Vimalachandran Dale
- Violante Tommaso
- Vovola Fernanda
- Vulliamy Paul
- W Endorf (Hennepin Healthcare) Frederick
- W Etchill Eric
- W L\uf6ffler Markus
- W L\uf6ffler Markus
- Wall Rosemary
- Wallwork Kate
- Ward Alex
- Warwick (University Hospital Southampton) David
- Waseem Saima
- Weaver Helen
- Wells Fiona
- Wen Jiaxin
- West Raha
- Whitehall Emma
- Wild Laura
- Wilkins Alex
- Williams Gethin
- Williams Matthew
- Winnand (University Hospital Aachen) Philipp
- Wong (Addenbrooke's Hospital) Ken
- Worku (Queen\u2019s Medical Centre Dawit
- Wright Naomi
- WS Ho (Leeds Teaching Hospitals NHS Trust Michael
- WT Ngu Albert
- y Cajal) Cristina Cerro (Hospital Universitario Ram\uf3n
- Y Oo (Department of Cardiothoracic Surgery Aung
- y Polit\ue9cnico La Fe) Blas Flor (Hospital Universitario
- Y van der Plas Willemijn
- Yalamanchili Seema
- Yershov (South Warwickshire NHS Foundation Trust) Danylo
- Young Richard
- Yousra Ahmed (Portsmouth Hospital NHS Trust) Simon Toh
- Yurttas Can
- Zadegan Frederic
- Zafar (Northwick Park Hospital) Noman
- Zakaria Rasheed
- Zambon Martina
- Zanini Nicola
- ZE Durst Alexander
- Zerbib Philippe
- Zonta (Ospedale San Biagio Sandro
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research
Kpi, a chaperone-usher pili system associated with the worldwide-disseminated high-risk clone Klebsiella pneumoniae ST-15.
- Author
- Publication venue
- 'Proceedings of the National Academy of Sciences'
- Publication date
- 01/01/2020
- Field of study
Control of infections caused by carbapenem-resistant Klebsiella pneumoniae continues to be challenging. The success of this pathogen is favored by its ability to acquire antimicrobial resistance and to spread and persist in both the environment and in humans. The emergence of clinically important clones, such as sequence types 11, 15, 101, and 258, has been reported worldwide. However, the mechanisms promoting the dissemination of such high-risk clones are unknown. Unraveling the factors that play a role in the pathobiology and epidemicity of K. pneumoniae is therefore important for managing infections. To address this issue, we studied a carbapenem-resistant ST-15 K. pneumoniae isolate (Kp3380) that displayed a remarkable adherent phenotype with abundant pilus-like structures. Genome sequencing enabled us to identify a chaperone-usher pili system (Kpi) in Kp3380. Analysis of a large K. pneumoniae population from 32 European countries showed that the Kpi system is associated with the ST-15 clone. Phylogenetic analysis of the operon revealed that Kpi belongs to the little-characterized γ2-fimbrial clade. We demonstrate that Kpi contributes positively to the ability of K. pneumoniae to form biofilms and adhere to different host tissues. Moreover, the in vivo intestinal colonizing capacity of the Kpi-defective mutant was significantly reduced, as was its ability to infect Galleria mellonella The findings provide information about the pathobiology and epidemicity of Kpi+K. pneumoniae and indicate that the presence of Kpi may explain the success of the ST-15 clone. Disrupting bacterial adherence to the intestinal surface could potentially target gastrointestinal colonization.The authors thank Dr Fidel Madrazo for help with transmission electron microscopy and confocal laser-scanning microscopy assays. This research was supported by Projects p-01216A and IJCI-2016-29524 (to A.P.), funded by the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) and the Minestry of Economy and Competetiveness (MINECO), respectively. It was also supported by Projects PI11/01034 (to M.P.), PI14/00059 and PI17/1482 (to M.P. and A.B.), and PI18/00501 (to G.B.), included in the National Plan for Scientific Research, Development and Technological Innovation 2013-2016 and funded by the Instituto de Salud Carlos III (ISCIII) and Subdirección General de Redes y Centros de Investigación Cooperativa, Ministerio de Economía, Industria y Competitividad, Spanish Network for Research in Infectious Diseases (REIPI RD16/0016/006) cofinanced by European Development Regional Fund “A way to achieve Europe” and operative program Intelligent Growth 2014-2020. Grant BFU2016-77835-R of the MINECO (to A.R.) also supported this research. E.G. was financially supported by the SEIMC project. J.C.V.-U. was financially supported by the PFIS (Contratos Predoctorales de Formación en Investigación en Salud) program (F18/00315); J.A.V. was financially supported by IN607A 2016/22; M.M.-G. was financially supported by a Clara Roy grant (SEIMC); A.B. was financially supported by the Miguel Servet program (ISCIII, Spain); B.K.R.-J. was financially supported by Marie S. Curie Action SaPhaDe project (MSCA-IF-GF-836754); and A.P. was financially supported by the Juan de la Cierva program (MINECO, IJCI-2016-29524).S
Modulation of Haemophilus influenzae interaction with hydrophobic molecules by the VacJ/MlaA lipoprotein impacts strongly on its interplay with the airways
- Author
- Almagro G. (Goizeder)
- Bengoechea J.A. (José A.)
- Caballero L. (Lucía)
- Conde-Alvarez R. (Raquel)
- Euba B. (Begoña)
- Fernández-Calvet A. (Ariadna)
- Garmendia J. (Junkal)
- Leigh-Bartholomew T. (Toby)
- Martí S. (Sara)
- Moleres J. (Javier)
- Morales X. (Xabier)
- Ortiz-de-Solorzano C. (Carlos)
- Ramos-Vivas J. (Jose)
- Rodríguez-Arce I. (Irene)
- Yuste J.E. (José Enrique)
- Publication venue
- 'The Nature Conservancy'
- Publication date
- 01/01/2018
- Field of study
Airway infection by nontypeable Haemophilus influenzae (NTHi) associates to chronic obstructive pulmonary disease (COPD) exacerbation and asthma neutrophilic airway inflammation. Lipids are key inflammatory mediators in these disease conditions and consequently, NTHi may encounter free fatty acids during airway persistence. However, molecular information on the interplay NTHi-free fatty acids is limited, and we lack evidence on the importance of such interaction to infection. Maintenance of the outer membrane lipid asymmetry may play an essential role in NTHi barrier function and interaction with hydrophobic molecules. VacJ/MlaA-MlaBCDEF prevents phospholipid accumulation at the bacterial surface, being the only system involved in maintaining membrane asymmetry identified in NTHi. We assessed the relationship among the NTHi VacJ/MlaA outer membrane lipoprotein, bacterial and exogenous fatty acids, and respiratory infection. The vacJ/mlaA gene inactivation increased NTHi fatty acid and phospholipid global content and fatty acyl specific species, which in turn increased bacterial susceptibility to hydrophobic antimicrobials, decreased NTHi epithelial infection, and increased clearance during pulmonary infection in mice with both normal lung function and emphysema, maybe related to their shared lung fatty acid profiles. Altogether, we provide evidence for VacJ/MlaA as a key bacterial factor modulating NTHi survival at the human airway upon exposure to hydrophobic molecules
Kpi, a chaperone-usher pili system associated with the worldwide-disseminated high-risk clone Klebsiella pneumoniae
- Author
- Alejandro Beceiro
- Antonio Romero
- Astrid Pérez
- Bruno Kotska Rodiño-Janeiro
- Calfee
- Darfeuille-Michaud
- David
- Di Martino
- Eva Gato
- Favre-Bonte
- Gato
- Germán Bou
- Jesus Oteo Iglesias
- Jose Ramos Vivas
- Juan A. Vallejo
- Juan Carlos Vázquez-Ucha
- Khater
- Laura Álvarez-Fraga
- Margarita Poza
- Marta Martínez-Guitián
- Martin
- Martin
- María Pérez-Vázquez
- Oteo
- Pedro J. Sola Campoy
- Porse
- Rumbo-Feal
- Soraya Rumbo-Feal
- Zimmermann
- Álvarez-Fraga
- Publication venue
- 'Proceedings of the National Academy of Sciences'
- Publication date
- Field of study
Effects of Subinhibitory Concentrations of Ceftaroline on Methicillin-Resistant Staphylococcus aureus (MRSA) Biofilms
- Author
- A Villegas-Estrada
- Axel Cloeckaert
- BJ Werth
- C Gil
- C Goerke
- C Pozzi
- Cristina Rodríguez-Mirones
- D Biek
- DL Gomes
- E O'Neill
- Felix Acosta
- G Landini
- GA O'Toole
- H Van Acker
- HS Joo
- I Odenholt
- J Cassat
- J Davies
- J Valle
- J Valle
- JB Kaplan
- JB Kaplan
- JB Kaplan
- JL Brooks
- Jose M. Icardo
- José Ramos-Vivas
- JP O'Gara
- K Lewis
- K Smith
- KE Barber
- KL Frank
- L Saravolatz
- LD Saravolatz
- Luis Martínez-Martínez
- M Blickwede
- María Lázaro-Díez
- N Hoiby
- N Subrt
- NK Archer
- PA Suci
- PC Braga
- PS Pottinger
- R Singh
- RM Donlan
- RP Novick
- S Rachid
- S Stefani
- Sara Remuzgo-Martínez
- SW Long
- V Khodaverdian
- X Zhou
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Segregation and associations of enological and agronomic traits in Graciano × Tempranillo wine grape progeny (Vitis vinifera L.)
- Author
- A Doligez
- A Hall
- A Ortega-Regules
- A Walker
- AM Jordao
- AP Viana
- AP Viana
- BG Coombe
- BG Coombe
- C Leeuwen Van
- Cristina M. Menéndez
- DI Jackson
- DS Falconer
- E Duchêne
- EE Cleland
- G Alleweldt
- G Fanizza
- GV Jones
- GV Jones
- H Fraga
- H-F Liu
- Ignacio Provedo
- J Bergqvist
- J Cacho
- J Ibáñez
- JE Bowers
- JE Bowers
- JF Harbertson
- JP Martín
- JR Clark
- JS Gladstones
- KM Sefc
- L Costantini
- LB Webb
- LB Webb
- M Baggiolini
- M Bayo-Canha
- M Nadal
- M Nadal
- M Shiraishi
- María del Mar Hernández
- MC Ramos
- MG Mullins
- ML Gonzalez-San Jose
- MO Downey
- MR Thomas
- MS Buttrose
- N Saint-Criq de Gaujelac
- N Vivas de Gaulejac
- P Chomé
- P This
- R Lai
- S Riaz
- Shiren Song
- V Núñez
- WM Kliewer
- X Wei
- Z Liang
- Z Liang
- Z Liang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Modernity and development: A critique
- Author
- Alan Peshkin
- Albert O. Hirschman
- Albert O. Hirschman
- Alejandro Portes
- Alejandro Portes
- Alejandro Portes
- Alejandro Portes
- Alejandro Portes
- Alex INKELES
- Alexander Eckstein
- Alexander Erlich
- Allan Schnaiberg
- Anibal Pinto Santa Cruz
- Antonio Mercader
- Armand Cuvillier
- Benjamin Higgins
- Bert F. Hoselitz
- Bert F. Hoselitz
- Carmelo Mesa-Lago
- Celso Furtado
- Celso Furtado
- Daniel Lerner
- David Apter
- David C. McClelland
- David H. Smith
- Edward C. Banfield
- Eliseo Vivas
- Emile Durkheim
- Emile Durkheim
- Emile Durkheim
- Emile Durkheim
- Emory Bogardus
- Everett E. Hagen
- Ferdinand Tonnies
- Frank Tannenbaum
- François Bourricaud
- Frederick B. Pike
- G. Rauch Von
- Gabriel Almond
- George I. Blanksten
- Gideon Sjoberg
- Gilbert W. Merkx
- Gino Germani
- Gino Germani
- Gunnar Myrdal
- Gustavo Lagos Matus
- H. Stuart Hughes
- Harry G. Johnson
- Herbert Spencer
- Herbert Spencer
- Hla Myint
- Irving Louis Horowitz
- Irving Louis Horowitz
- James M. Malloy
- James M. Malloy
- James M. Malloy
- John B. Stephenson
- John F. C. Turner
- John Gillin
- John Walton
- Jorge Ahumada
- Jose Carlos Mariategui
- Jose L. Moreno
- Joseph A. Kahl
- Joseph Grunwald
- Joseph R. Gusfield
- Juan Jose Sebreli
- Karl Marx
- Karl Marx
- Karl Marx
- Louis Wirth
- Manuel Mujica Lainez
- Marion J. Levy
- Martin Needler
- Mary MATOSSIAN
- Maurice Zeitlin
- Max Weber
- Oscar Handlin
- Peter N. Amato
- Ralf Dahrendorf
- Ralph D. Braibanti
- Ralph Linton
- Raul Prebisch
- Reinhard Bendix
- Reinhard bendix
- Rene Vandendries
- Richard Sennett
- Robert Dahl
- Robert E. Park
- Robert I. Sinai
- Robert N. Bellah
- Robert Redfield
- Robert Redfield
- Roger Vekemans
- Samuel Ramos
- Seymour M. Lipset
- Shmuel n. Eisenstadt
- Shmuel n. Eisenstadt
- Talcott Parsons
- Talcott Parsons
- Talton F. Ray
- Torcuato s. Tella DI
- U.S. Department of Justice
- Universidad de Chile
- W. LLOYD Warner
- Walt W. Rostow
- Wilbert E. Moore
- William A. Mangin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Stress neuropeptide levels in adults with chest pain due to coronary artery disease: potential implications for clinical assessment
- Author
- A. A. Ermolaev
- A. A. Fomin
- A. A. Grace
- A. A. J. Adgey
- A. A. J. Adgey
- A. A. J. Adgey
- A. Abdelfattah
- A. Affatato
- A. Aiello
- A. Albuquerque
- A. Albuquerque
- A. Aleixo
- A. Aleixo
- A. Aleixo
- A. Aleixo
- A. Aleixo
- A. Aleixo
- A. Aleixo
- A. Aleixo
- A. Aleixo
- A. Aleixo
- A. Aleixo
- A. Aleksic
- A. Aleksova
- A. Alexandrescu
- A. Altamirano
- A. Alvarez-San Gabriel
- A. Anzoletti Boscolo
- A. Arias
- A. Ariza Sole
- A. Ariza Sole
- A. Ariza Sole
- A. Asif
- A. Aurelio
- A. Bellemain-Appaix
- A. Berezin
- A. Beyaztas
- A. Birdane
- A. Birdane
- A. Birdane
- A. Birdane
- A. Birdane
- A. Bittlinsky
- A. Botelho
- A. Botelho
- A. Botelho
- A. Boytsov
- A. Brzozowska-Czarnek
- A. C. C. Carvalho
- A. C. C. Carvalho
- A. C. C. Carvalho
- A. C. Ferreira
- A. C. Van Rossum
- A. C. Van Rossum
- A. C. Van Rossum
- A. Cabiati
- A. Calabro
- A. Campanile
- A. Campo
- A. Cattabiani
- A. Cavusoglu
- A. Cavusoglu
- A. Cequier Fillat
- A. Chaib
- A. Chernova
- A. Comella
- A. Condac
- A. Conti
- A. Contine
- A. Correia
- A. Cristea
- A. De Caterina
- A. De Miguel
- A. Dibra
- A. Diego
- A. Dominguez-Rodriguez
- A. Drumond
- A. Drumond
- A. Drumond
- A. Drumond
- A. Dushpanova
- A. Erglis
- A. Erglis
- A. F. Simoes Marques Assuncao Caetano
- A. Fareed
- A. Faustino
- A. Faustino
- A. Faustino
- A. Faustino
- A. Fernandez-Ortiz
- A. Fernandez-Ortiz
- A. Fernandez-Ortiz
- A. Fiarresga
- A. Fruntelata
- A. Fruntelata
- A. G. Aroutunov
- A. G. Fruntelata
- A. G. Nikishin
- A. G. Nikishin
- A. G. Rebuzzi
- A. Garcia Escudero
- A. Garcia Quintana
- A. Geppert
- A. Gnanaraj
- A. Gonella
- A. Goodkova
- A. Grave
- A. Grave
- A. Hirsch
- A. Hirsch
- A. Hirsch
- A. Horvath
- A. I. Hassan
- A. I. Suceveanu
- A. I. Suceveanu
- A. Ibatov
- A. Ibatov
- A. Iniguez
- A. Ionac
- A. Izzo
- A. Izzo
- A. Izzo
- A. J. Aleksandra Jovelic
- A. J. Palomino Doza
- A. J. Six
- A. Jegou
- A. Jovelic
- A. Kalinauskas
- A. Kasai
- A. Kastrati
- A. Kawamura
- A. Kokotos
- A. Konopka
- A. Kral
- A. Kruger
- A. L. Bartorelli
- A. L. Volkova
- A. Lallo
- A. Leitao
- A. Leitao
- A. Leitao Marques
- A. Leitao Marques
- A. Leitao Marques
- A. Leitao Marques
- A. Leitao-Marques
- A. Leitao-Marques
- A. Leitao-Marques
- A. Leitao-Marques
- A. Leitao-Marques
- A. Linhart
- A. Linhart
- A. Llacer
- A. Lopez-March
- A. Lousinha
- A. Lousinha
- A. M. Abdelbary
- A. M. Fareed
- A. M. Leitao Marques
- A. M. Leitao-Marques
- A. M. Leitao-Marques
- A. M. Leitao-Marques
- A. M. Leone
- A. M. Ramirez Rodriguez
- A. M. Van Der Laan
- A. M. Van Der Laan
- A. Maisel
- A. Manerba
- A. Martinez Martinez
- A. Marzari
- A. Mayr
- A. Medina Fernandez Aceytuno
- A. Melnikov
- A. Menozzi
- A. Mercadier
- A. Mosterd
- A. Mousa
- A. Mysiak
- A. N. Kitsiou
- A. Naggar
- A. Nardelli
- A. Neji
- A. Neskovic
- A. Neskovic
- A. Omura
- A. Palazzuoli
- A. Pani
- A. Parspour
- A. Pereira
- A. Pereira
- A. Perez De Prado
- A. Pernat
- A. Peterschroeder
- A. Peterschroeder
- A. Petris
- A. Proclemer
- A. Proclemer
- A. Pullara
- A. Reda
- A. Reggiani
- A. Rialan
- A. Rincon De Arellano
- A. Rodrigues
- A. Rodriguez
- A. Rodriguez-Gonzalez
- A. Rodriguez-Gonzalez
- A. Rusali
- A. S. Mullasari
- A. S. Postadzhiyan
- A. Samborska-Sablik
- A. Sanchez Gonzalez
- A. Sanchez-Grande-Flecha
- A. Sanchez-Grande-Flecha
- A. Sarantopoulos
- A. Scafa Udriste
- A. Scafa Udriste
- A. Schaefer
- A. Schmidt
- A. Schoemig
- A. Schratter
- A. Schratter
- A. Sciahbasi
- A. Shotan
- A. Shpektor
- A. Silva
- A. Silva
- A. Silva
- A. Silva
- A. Silva
- A. Silva
- A. Silva
- A. Silva
- A. Silva
- A. Silva
- A. Silva
- A. Silva
- A. Stojkovic
- A. Stojkovic
- A. Stojkovic
- A. Stojkovic
- A. Suarez-Barrientos
- A. Suceveanu
- A. Suceveanu
- A. Suzuki
- A. Swiatkowski
- A. T. Timoteo
- A. T. Timoteo
- A. T. Timoteo
- A. T. Timoteo
- A. T. Timoteo
- A. T. Timoteo
- A. T. Timoteo
- A. Tomlin
- A. Toste
- A. Toste
- A. Toste
- A. Unalir
- A. Unalir
- A. Urbanik
- A. V. Starodubova
- A. V. Timofeev
- A. Van Der Laan
- A. Viertel
- A. Vorlat
- A. Weaver
- A. Y. A. Goodkova
- A. Y. Suvorov
- A. Yukawa
- A. Zhivkov
- A.- C. Martin
- B. B. Ong
- B. B. Ong
- B. Berdaoui
- B. Berta
- B. Brockmeyer
- B. Del Taglia
- B. Doka
- B. E. Backus
- B. Finkov
- B. Fontanella
- B. Franci
- B. G. Branko Gligic
- B. Getaldic
- B. Gligic
- B. Gok
- B. Gorenek
- B. Gorenek
- B. Gorenek
- B. Gorenek
- B. Gorenek
- B. Ibanez
- B. Ibanez
- B. Ibanez Cabeza
- B. J. Bouma
- B. Jedaida
- B. Merkely
- B. Merkely
- B. Merkely
- B. Metzler
- B. Meuris
- B. Minescu
- B. Moquet
- B. Putnikovic
- B. Putnikovic
- B. Ruiz-Mateos
- B. Ruiz-Mateos
- B. Sasko
- B. Schei
- B. Silva
- B. Silva
- B. Silva
- B. Silva
- B. Silva
- B. Smith
- B. Sredniawa
- B. Steuerova
- B. Timuralp
- B. Trimarco
- B. Valente
- B. Vega
- B. Vogel
- B. Vogel
- B. Wasan
- B. Xu
- C. A. Den Uil
- C. Acebal
- C. Acebal
- C. Aguiar
- C. Aguiar
- C. Aguiar
- C. Andrioaia
- C. Andrys
- C. Arsenescu-Georgescu
- C. Autore
- C. B. Dias
- C. B. Dias
- C. Bonanad
- C. C. Fang
- C. Cabades
- C. Caiati
- C. Calisto
- C. Calisto
- C. Calisto
- C. Calisto
- C. Cardwell
- C. Carriere
- C. Cavallini
- C. Cherfils
- C. Ciccarese
- C. Ciurea
- C. Cosson
- C. Cozma
- C. Crowe
- C. Cuellas
- C. Demirustu
- C. Demirustu
- C. Demirustu
- C. Demirustu
- C. Dubois
- C. Dubois
- C. Dubois
- C. Enjuanes-Grau
- C. Enjuanes-Grau
- C. Faustino
- C. Ferrari
- C. Fonseca
- C. Fonseca
- C. Fonseca
- C. Fonseca
- C. Fonseca
- C. Fonseca
- C. Fresco
- C. Fresco
- C. G. Owens
- C. Garcia-Garcia
- C. Ginghina
- C. Grasso
- C. Hassager
- C. Hassager
- C. Hernandez
- C. Hernandez Garcia
- C. Hernandez Garcia
- C. Hernandez Luis
- C. Hernandez Luis
- C. Hernandez Luis
- C. Homorodean
- C. I. Santos De Sousa
- C. I. Stoicescu
- C. J. Mc Cann
- C. J. Terkelsen
- C. J. Vrints
- C. Jorge
- C. Jorge
- C. Jorge
- C. Jorge
- C. L. Huang
- C. L. Yu
- C. Lombardi
- C. Macarie
- C. Macarie
- C. Macaya
- C. Macaya
- C. Martinez-Sanchez
- C. Michalakeas
- C. Moretti
- C. Morley
- C. Mornos
- C. Mornos
- C. Mueller
- C. Navarro
- C. Olariu
- C. P. G. Carlos Pena Gil
- C. Papadopoulos
- C. Paulo
- C. Paulo
- C. Pena-Gil
- C. Perigaud
- C. Poggioni
- C. Pop
- C. Pop
- C. Pop
- C. Pop
- C. Ronco
- C. Rubio-Iglesias-Garcia
- C. Rubio-Iglesias-Garcia
- C. Santos
- C. Sinescu
- C. Sinescu
- C. Spaulding
- C. Tapia
- C. Tapia Ballesteros
- C. Tapia Ballesteros
- C. Tapia Ballesteros
- C. Teodorescu
- C. Tessa
- C. Thalhammer
- C. Trani
- C. Udroiu
- C. Vignali
- C. Villa
- C. Wibberley
- C.- H. Tang
- D. Ardissino
- D. Becker
- D. Becker
- D. Blondhaim
- D. Bonnefont-Rousselot
- D. Brieger
- D. Caeiro
- D. Caeiro
- D. Caeiro
- D. Caeiro Pereira
- D. Constantinescu
- D. Cozma
- D. Cruz
- D. D. Ionescu
- D. D. Ionescu
- D. D. Ionescu
- D. Datta
- D. Deleanu
- D. Djordjevic Radojkovic
- D. Djordjevic Radojkovic
- D. Djordjevic-Radojkovic
- D. Djordjevic-Radojkovic
- D. Djordjevic-Radojkovic
- D. Djordjevic-Radojkovic
- D. Dobreanu
- D. Dobreanu
- D. Dragulescu
- D. Duveau
- D. Fredman
- D. Freitas
- D. Fusco
- D. Hazarbasanov
- D. Horak
- D. Horstkotte
- D. Horstkotte
- D. Ilic
- D. Juhnevica
- D. Juhnevica
- D. Juzar
- D. Kokkinos
- D. Labudovic
- D. Lehmann
- D. Lehmann
- D. Leibowitz
- D. M. Gualandro
- D. Milic
- D. Milicevic
- D. Milicevic
- D. Milicic
- D. Milicic
- D. Muser
- D. Muser
- D. Nait
- D. Olinic
- D. Olinic
- D. Ortiz Berbel
- D. Pereira
- D. Poyares
- D. R. Almeida
- D. R. Almeida
- D. Rott
- D. Sakac
- D. Sanmiguel
- D. Silva
- D. Silva
- D. Silva
- D. Silva
- D. Sondore
- D. Sondore
- D. Stanojevic
- D. Stanojevic
- D. Staub
- D. Tobing
- D. Tomcikova
- D. Townsend
- D. Tsaregorodtsev
- D. Vindis
- D. Vinereanu
- D. Vinogradova
- D. Vivas
- D. Vivas Balcones
- D. Vondrakova
- D. Wichterle
- D. Zamfir
- D. Zanna
- E. A. A. Emad Abu Assi
- E. A. Spiridonova
- E. Abu-Assi
- E. Abu-Assi
- E. Arroyo Ucar
- E. Arroyo Ucar
- E. Assanelli
- E. Assanelli
- E. Assante Di Panzillo
- E. Bobescu
- E. Bozas
- E. Bustamante
- E. Caballero Dorta
- E. Cerone
- E. Conti
- E. Craiu
- E. Craiu
- E. Craiu
- E. Craiu
- E. Craiu
- E. Craiu
- E. Crolla
- E. D. E. Papathanassoglou
- E. Dito
- E. Dumitru
- E. Entok
- E. Esplugas Oliveras
- E. Esplugas Oliveras
- E. Esplugas Oliveras
- E. F. Christensen
- E. Fabris
- E. Filippi
- E. Fraile
- E. Franco
- E. G. Mast
- E. Gainoiu
- E. Grikstaite
- E. Guillerm
- E. Hernadez Ortega
- E. J. Williams
- E. Jorge
- E. Jorge
- E. Jorge
- E. K. Iliodromitis
- E. Kletsiou
- E. Kovacs
- E. Lioy
- E. Madronal-Cerezo
- E. Maekawa
- E. N. Semernin
- E. N. Vorobyova
- E. Nechita
- E. Noiman
- E. Okisheva
- E. Paredes
- E. Pasotti
- E. Pavli
- E. Pereira
- E. Pereira
- E. Salengro
- E. Solinas
- E. T. Iliodromitis
- E. Tamayo
- E. Tavlueva
- E. Trendafilova
- E. V. Privalova
- E. Vandecasteele
- E. Vasilieva
- E. Voltirakis
- E. Zatarain Nicolas
- E. Zima
- F. Addad
- F. Afamefule
- F. Agostini
- F. Angeli
- F. Aros
- F. Betbout
- F. Beygui
- F. Bianchetti
- F. Blanco
- F. Borgognoni
- F. Bosa-Ojeda
- F. Bosa-Ojeda
- F. Bulletti
- F. Burzotta
- F. Caetano
- F. Caetano
- F. Caetano
- F. Caetano
- F. Calvo
- F. Canario-Almeida
- F. Castro-Ferreira
- F. Cintra
- F. Cionini
- F. Colivicchi
- F. Conrotto
- F. Corbetti
- F. Corsi
- F. Corsi
- F. Corsi
- F. Costa
- F. Crea
- F. Crea
- F. Crea
- F. D'ascenzo
- F. De Somer
- F. Feliciano
- F. Fernandez-Vazquez
- F. Franco
- F. Franco
- F. Franco
- F. G. M. Braga
- F. Guliyev
- F. Hautieva
- F. Holy
- F. Holy
- F. J. Berdejo Gago
- F. Keshavarzi
- F. L. Voinea
- F. L. Voinea
- F. M. Lauri
- F. Maatouk
- F. Maklady
- F. Maklady
- F. Mantovani
- F. Marrero Rodriguez
- F. Marrero Rodriguez
- F. Marrero-Rodriguez
- F. Marrero-Rodriguez
- F. Martens
- F. Mateen
- F. Mitu
- F. Miyake
- F. Mlejnsky
- F. Moscoso Costa
- F. Ortan
- F. Possa
- F. Quinzani
- F. Sampaio
- F. Saraiva
- F. Saraiva
- F. Saraiva
- F. Sciuto
- F. Sogorb
- F. Tromp
- F. Van De Werf
- F. Vrapi
- F. X. Hager
- F. Yuksel
- F. Yuksel
- F. Zijlstra
- F. Zijlstra
- F. Zijlstra
- G. Ambrosio
- G. Anton
- G. Antonelli
- G. Ballard
- G. Barbati
- G. Bayet
- G. Bernardi
- G. Bernardi
- G. Biasillo
- G. Biasillo
- G. Biondi Zoccai
- G. Blanco Palacios
- G. Blanco-Palacios
- G. Caires
- G. Caires
- G. Caires
- G. Caires
- G. Caires
- G. Cardoso
- G. Casella
- G. Casolo
- G. Cayla
- G. Conte
- G. Costa
- G. Costa
- G. Datcu
- G. Ferraiuolo
- G. Ferraiuolo
- G. Ferraiuolo
- G. Fradella
- G. Geraci
- G. Gheorghe
- G. Gigena
- G. Groenefeld
- G. Honisz
- G. I. Furmenko
- G. I. Furmenko
- G. I. Furmenko
- G. Iaccarino
- G. Ifteni
- G. Jakl
- G. Jakl
- G. Klug
- G. Koracevic
- G. Koracevic
- G. Koracevic
- G. Koracevic
- G. Koracevic
- G. Koracevic
- G. Koracevic
- G. Krljanac
- G. Lauri
- G. Lauri
- G. Leurent
- G. Longo
- G. M. Nasr
- G. M. Nasr
- G. M. Shaban
- G. Marenzi
- G. Marenzi
- G. Mcdowell
- G. Mihaylov
- G. Mihaylov
- G. Montalescot
- G. Morais
- G. Morocutti
- G. Morocutti
- G. P. Arutyunov
- G. P. Trevi
- G. Panic
- G. Panic
- G. Papadimitriou
- G. Pencheva
- G. Rouault
- G. S. Gheorghe
- G. Saatashvili
- G. Santulli
- G. Sanz
- G. Schuler
- G. Schuler
- G. Silva
- G. Silva
- G. Sinagra
- G. Storozhakov
- G. Tatu - Chitoiu
- G. Tatu Chitoiu
- G. Tatu Chitoiu
- G. Tatu-Chitoiu
- G. Tatu-Chitoiu
- G. Tatu-Chitoiu
- G. Tatu-Chitoiu
- G. Unger
- G. Verzura
- G. Vianello
- G. Viviani
- G. Y. Song
- G. Y. Szabo
- G. Y. Szabo
- G. Yanes-Bowden
- H. A. De Bruin
- H. A. Katus
- H. Badran
- H. Bejiqi
- H. C. Carvalho
- H. C. Lee
- H. Cafe
- H. Cafe
- H. Cafe
- H. Cafe
- H. Dores
- H. Dores
- H. Dores
- H. Dores
- H. Dores
- H. Dores
- H. Dores
- H. Dores
- H. Dores
- H. Dores
- H. Drissa
- H. E. Botker
- H. Elassar
- H. G. Hayrapetyan
- H. Gamra
- H. Goncalves
- H. Goncalves
- H. Gonzalez-Pacheco
- H. Grunfeldova
- H. Hammerman
- H. Hammerman
- H. Hammerman
- H. Hazui
- H. Higuchi
- H. J. Trappe
- H. Kalim
- H. Khaled Nagi
- H. Le Breton
- H. Lin
- H. M. Cafe
- H. Martins
- H. Martins
- H. Martins
- H. Mitsuoka
- H. Morley
- H. Mozina
- H. Musha
- H. Pintaric
- H. R. Andersen
- H. Ribeiro
- H. Ribeiro
- H. Rus
- H. S. H. Shaalan
- H. S. Kamal
- H. Shinagawa
- H. Takehana
- H. Thiele
- H. Thiele
- H. Uthoff
- H. Vakili
- H. Velinov
- H. Wirdemann
- H. Y. Qian
- H.- T. Hsin
- I. A. Duro Aguado
- I. A. Gonzalez
- I. A. Gonzalez
- I. A. Gonzalez Garcia
- I. A. Kuznetsova
- I. Arroja
- I. Arroja
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- S. Costa
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- S. Farhan
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- S. H. Borovci
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- S. I. Dragulescu
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- S. Intwala
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- S. Kafedzic
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- S. R. N. Leal
- S. R. R. Sergio Raposeiras Roubin
- S. Rafajlovski
- S. Raposeiras Roubin
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- S. Robalo Martins
- S. Robalo Martins
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- S. S. Yakushin
- S. S. Yakushin
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- T. Marandi
- T. Masuyama
- T. Minora
- T. Mizutani
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- T. Naka
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- T. Nanea
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- V. Lorente Tordera
- V. Lorente Tordera
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- V. Martinez Garcia
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- V. Nikolic Heitzler
- V. Nikolic Heitzler
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- W. P. Lee
- W. P. Lee
- W. P. Lee
- W. Rottbauer
- X. Bosch
- X. Wu
- Y. Agmon
- Y. Agmon
- Y. Akashi
- Y. Beaini
- Y. Cavusoglu
- Y. Cavusoglu
- Y. Cavusoglu
- Y. Cavusoglu
- Y. Cavusoglu
- Y. Chen
- Y. D. Kim
- Y. D. Tang
- Y. D. Tang
- Y. Eki
- Y. Endo
- Y. H. Nam
- Y. Ishibashi
- Y. J. Wu
- Y. J. Wu
- Y. J. Yang
- Y. J. Yany
- Y. Levy
- Y. Li
- Y. Maazoun
- Y. N. Belenkov
- Y. Ohishi
- Y. Sato
- Y. Simova
- Y. T. F. N. Jao
- Y. Takeda
- Y. Van Belleghem
- Y. Zhang
- Y. Zhao
- Z. Babic
- Z. Babic
- Z. C. H. Cherneva
- Z. Dridi
- Z. K. Wu
- Z. Kalarus
- Z. Keca
- Z. Monhart
- Z. Motovska
- Z. Pagava
- Z. Perisic
- Z. Perisic
- Z. Perisic
- Z. Plazonic
- Z. Plazonic
- Z. Radovanovic
- Z. S. Jenei
- Z. Sablik
- Z. Vasiljevic
- Z. Y. Zhao
- Z. Y. Zhao
- Z.- S. Chen
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/10/2010
- Field of study
: Substance P (SP) and neuropeptide Y (NPY) are neuropeptides
involved in nociception. The study of biochemical markers of pain in
communicating critically ill coronary patients may provide insight for pain
assessment and management in critical care. Purpose of the study was to
to explore potential associations between plasma neuropeptide levels and
reported pain intensity in coronary critical care adults, in order to test the
reliability of SP measurements for objective pain assessment in critical
care
Safety of hospital discharge before return of bowel function after elective colorectal surgery
- Author
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- Aba M.
- Abad-Motos A.
- Abbasguliyev H.
- Abdelgalil R.
- Abdelhameed F.
- Abdulrahman N.
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- Žebrák R.
- Publication venue
- 'Wiley'
- Publication date
- 01/04/2020
- Field of study
© 2020 BJS Society Ltd Published by John Wiley & Sons LtdBackground: Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function. Methods: A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien–Dindo classification system. Results: A total of 3288 patients were included in the analysis, of whom 301 (9·2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4–7) and 7 (6–8) days respectively (P < 0·001). There were no significant differences in rates of readmission between these groups (6·6 versus 8·0 per cent; P = 0·499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0·90, 95 per cent c.i. 0·55 to 1·46; P = 0·659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34·7 versus 39·5 per cent; major 3·3 versus 3·4 per cent; P = 0·110). Conclusion: Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients