46 research outputs found

    Parallel framework for earthquake induced response computation of the SDOF structure

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    Parallel computing briskly diminishes computation time through simultaneous use of multiple computing resources. In this research, parallel computing techniques have been developed to parallelize a program for obtaining a response of single degree of freedom (SDOF) structure under earthquake loading. The study uses Distributed Memory Processors (DMP) hardware architecture and Message Passing Interface (MPI) compilers directives to parallelize the program. The program is made parallel by domain decomposition. Concurrency in the program is created by dividing the program into two parts to run on different computers, calculating forced response and free response of the first half and the second half. Parallel framework successfully creates concurrency and finds structural responses in significant lesser time than sequential programs

    Knowledge, attitude, and practices of complementary and alternative medication usage in patients of type II diabetes mellitus

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    Introduction Complementary and alternative medicine (CAM) is becoming popular among individuals affected by chronic diseases, such as diabetes mellitus. We aimed to determine the knowledge, attitude, and practices of complementary and alternative medicine use among type 2 diabetes patients in Karachi, Pakistan. Methods An observational, prospective, cross-sectional study was conducted in the institute of diabetology in a tertiary care hospital in Pakistan from 1st March 2018 till 31st August 2018. All patients of type 2 diabetes mellitus attending the clinic for routine follow-up visits during the study period were interviewed. Their demographic characteristics, clinical data, and knowledge, attitude, practices towards use of CAM products were assessed. Data was managed using SPSS for Windows version 16.0 (SPSS Inc, Chicago, IL). Results CAM therapies were being used by 151 (57.8%) individuals. Herbs (n = 121; 80.1%), specific diets (n = 98; 64.9%), and cupping (n = 68; 45.0%) were the most readily utilized CAM practices. CAM practices were associated with diabetes-related complications [p \u3c 0.000; Odds Ratio (OR) 2.57; Confidence Interval (CI) 1.53, 4.34], poor glycemic control (p \u3c 0.000; OR 0.29; CI 0.17, 0.5), lack of trust in pharmaceutical products (p \u3c 0.000; OR 5.08; CI 2.28, 11.32), poor patient-doctor relationship (p = 0.06; OR 1.47; CI 0.26, 8.17), CAM products being readily available and cheaper (p \u3c 0.000; OR 6.1; CI 3.02, 12.32), and belief that CAM products have fewer side effects (p \u3c 0.000; OR 12.32; CI 6.83, 22.22) and can help in diabetes control (p \u3c 0.000; OR 35.76; CI 16.79, 76.15). Conclusion Use of complementary medicine products among Pakistani diabetic population is high. Herbs and specific diets were common modes of CAM practices. Use of CAM showed significant association with female gender, older age, unemployment, longer duration of diabetes, diabetes-related complications, and poor glycemic control

    Efficient design in building construction with rubber bearing in medium risk seismicity: case study and assessment

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    Earthquakes pose tremendous threats to life, property and a country's economy, not least due to their capability of destroying buildings and causing enormous structural damage. The hazard from ground excitations should be properly assessed to mitigate their action on building structures. This study is concerned with medium risk seismic regions. Specifically, the heavily populated capital city Dhaka in Bangladesh has been considered. Recent earthquakes that occurred inside and very close to the city have manifested the city's earthquake sources and vulnerability. Micro-seismicity data supports the existence of at least four earthquake source points in and around Dhaka. The effects of the earthquakes on buildings are studied for this region. Rubber base isolation is selected as an innovative option to lessen seismic loads on buildings. Case studies have been carried out for fixed and isolated based multi-storey buildings. Lead rubber bearing and high damping rubber bearing have been designed and incorporated in building bases. Structural response behaviours have been evaluated through static and dynamic analyses. For the probable severe earthquake, rubber bearing isolation can be a suitable alternative as it mitigates seismic effects, reduces structural responses and provides structural and economic benefits

    Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

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    Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

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    Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

    Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015)

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    Computer aided seismic and fire retrofitting analysis of existing high rise reinforced concrete buildings

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    This book details the analysis and design of high rise buildings for gravity and seismic analysis. It provides the knowledge structural engineers need to retrofit existing structures in order to meet safety requirements and better prevent potential damage from such disasters as earthquakes and fires. Coverage includes actual case studies of existing buildings, reviews of current knowledge for damages and their mitigation, protective design technologies, and analytical and computational techniques. This monograph also provides an experimental investigation on the properties of fiber reinforced concrete that consists of natural fibres like coconut coir and also steel fibres that are used for comparison in both Normal Strength Concrete (NSC) and High Strength Concrete (HSC). In addition, the authors examine the use of various repair techniques for damaged high rise buildings. The book will help upcoming structural design engineers learn the computer aided analysis and design of real existing high rise buildings by using ACI code for application of the gravity loads, UBC- 97 for seismic analysis, and retrofitting analysis by computer models. It will be of immense use to the student community, academicians, consultants, and practicing professional engineers and scientists involved in the planning, design, execution, inspection, and supervision for the proper retrofitting of buildings

    Impact assessment of rainfall-vegetation on sedimentation and predicting erosion-prone region by GIS and RS

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    Water reservoirs are facing universal sedimentation problems worldwide. Land covers, whether natural or manmade, eventually change, and the vegetation cover and rainfall have a great effect on the sediment load. Traditional techniques for analysing this problem are time-consuming and spatially limited. Remote sensing (RS) provides a convenient way to observe land cover changes, and geographic information system (GIS) provides tools for geographic analysis. This study demonstrates a GIS-based methodology for calculating the impact of vegetation and rainfall on the sediment load using remotely sensed data. Moderate resolution imaging spectroradiometer data were used to observe temporal changes in the vegetation-cover area of the watershed surface. The total drainage area for the reservoir was calculated from shuttle radar topographic mission data. The annual rainfall amount was used to compute the annual available rainwater for the watershed, and the impact of the annual available rainwater on the vegetation-covered area was determined. In addition, areas that were adding sedimentation to the reservoir were identified. An inverse relationship between the rainfall and vegetation cover was observed, clearly showing the triggering of erosion

    Effect of Fibers on High-Temperature Mechanical Behavior and Microstructure of Reactive Powder Concrete

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    This study was aimed to investigate the effect of steel, polypropylene (PP), and hybrid (steel + PP) fibers on high-temperature mechanical properties of reactive powder concrete (RPC). The mechanical properties considered are cubic compressive strength, axial or prismatic compressive strength, split-tensile strength, flexural strength, elastic modulus, peak strain, and stress-strain behavior. The strength recession due to high temperature was investigated at micro level by scanning electron microscope, energy dispersive X-ray spectroscopy, X-ray diffraction, mercury intrusion porosity, thermogravimetric, and differential scanning calorimetry analyses. The high-temperature tests were carried out at target temperatures of 120, 300, 500, 700, and 900 °C. The hot-state compressive strength of RPC started to decrease at 120 °C; however, a partial recovery at 300 °C and a gradual decrease above 300 °C were observed. The degradation of split-tensile strength, flexural strength, and elastic modulus were gradual with increasing temperature despite the effect of different fibers. Whereas, the peak strain was gradually increasing up to 700 °C. However, after 700 °C, it remained unchanged. Steel fiber reinforced RPC (SRPC) and hybrid fiber reinforced RPC (HRPC) showed a ductile behavior. PP fiber reinforced RPC (PRPC) showed a quite brittle behavior up to 300 °C; however, further heating made the microstructure porous and it became ductile too. Overall the performance of SRPC and HRPC were superior to PRPC because of higher modulus of elasticity, higher strength, and better fire resistance of steel fibers. Fiber reinforced RPC was found to have better fire resistance than traditional types of concrete based on comparative studies with the provisions of design codes and earlier research. The constitutive equations developed can be utilized in computer programs for structural design of RPC structures exposed to fire
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