254 research outputs found
Mixed and discontinuous finite volume element schemes for the optimal control of immiscible flow in porous media
We introduce a family of hybrid discretisations for the numerical
approximation of optimal control problems governed by the equations of
immiscible displacement in porous media. The proposed schemes are based on
mixed and discontinuous finite volume element methods in combination with the
optimise-then-discretise approach for the approximation of the optimal control
problem, leading to nonsymmetric algebraic systems, and employing minimum
regularity requirements. Estimates for the error (between a local reference
solution of the infinite dimensional optimal control problem and its hybrid
approximation) measured in suitable norms are derived, showing optimal orders
of convergence
Competing mechanisms of stress-assisted diffusivity and stretch-activated currents in cardiac electromechanics
We numerically investigate the role of mechanical stress in modifying the
conductivity properties of the cardiac tissue and its impact in computational
models for cardiac electromechanics. We follow a theoretical framework recently
proposed in [Cherubini, Filippi, Gizzi, Ruiz-Baier, JTB 2017], in the context
of general reaction-diffusion-mechanics systems using multiphysics continuum
mechanics and finite elasticity. In the present study, the adapted models are
compared against preliminary experimental data of pig right ventricle
fluorescence optical mapping. These data contribute to the characterization of
the observed inhomogeneity and anisotropy properties that result from
mechanical deformation. Our novel approach simultaneously incorporates two
mechanisms for mechano-electric feedback (MEF): stretch-activated currents
(SAC) and stress-assisted diffusion (SAD); and we also identify their influence
into the nonlinear spatiotemporal dynamics. It is found that i) only specific
combinations of the two MEF effects allow proper conduction velocity
measurement; ii) expected heterogeneities and anisotropies are obtained via the
novel stress-assisted diffusion mechanisms; iii) spiral wave meandering and
drifting is highly mediated by the applied mechanical loading. We provide an
analysis of the intrinsic structure of the nonlinear coupling using
computational tests, conducted using a finite element method. In particular, we
compare static and dynamic deformation regimes in the onset of cardiac
arrhythmias and address other potential biomedical applications
Stabilized mixed approximation of axisymmetric Brinkman flows
This paper is devoted to the numerical analysis of an augmented finite element approximation of the axisymmetric Brinkman equations. Stabilization of the variational formulation is achieved by adding suitable Galerkin least-squares terms, allowing us to transform the original problem into a formulation better suited for performing its stability analysis. The sought quantities (here velocity, vorticity, and pressure) are approximated by Raviart−Thomas elements of arbitrary order k ≥ 0, piecewise continuous polynomials of degree k + 1, and piecewise polynomials of degree k, respectively. The well-posedness of the resulting continuous and discrete variational problems is rigorously derived by virtue of the classical Babuška–Brezzi theory. We further establish a priori error estimates in the natural norms, and we provide a few numerical tests illustrating the behavior of the proposed augmented scheme and confirming our theoretical findings regarding optimal convergence of the approximate solutions
Finite element and finite volume-element simulation of pseudo-ECGs and cardiac alternans
In this paper, we are interested in the spatio-temporal dynamics of the transmembrane potential in paced isotropic and anisotropic cardiac tissues. In particular, we observe a specific precursor of cardiac arrhythmias that is the presence of alternans in the action potential duration. The underlying mathematical model consists of a reaction–diffusion system describing the propagation of the electric potential and the nonlinear interaction with ionic gating variables. Either conforming piecewise continuous finite elements or a finite volume-element scheme are employed for the spatial discretization of all fields, whereas operator splitting strategies of first and second order are used for the time integration. We also describe an efficient mechanism to compute pseudo-ECG signals, and we analyze restitution curves and alternans patterns for physiological and pathological cardiac rhythms
Nonlinear diffusion & thermo-electric coupling in a two-variable model of cardiac action potential
This work reports the results of the theoretical investigation of nonlinear
dynamics and spiral wave breakup in a generalized two-variable model of cardiac
action potential accounting for thermo-electric coupling and diffusion
nonlinearities. As customary in excitable media, the common Q10 and Moore
factors are used to describe thermo-electric feedback in a 10-degrees range.
Motivated by the porous nature of the cardiac tissue, in this study we also
propose a nonlinear Fickian flux formulated by Taylor expanding the voltage
dependent diffusion coefficient up to quadratic terms. A fine tuning of the
diffusive parameters is performed a priori to match the conduction velocity of
the equivalent cable model. The resulting combined effects are then studied by
numerically simulating different stimulation protocols on a one-dimensional
cable. Model features are compared in terms of action potential morphology,
restitution curves, frequency spectra and spatio-temporal phase differences.
Two-dimensional long-run simulations are finally performed to characterize
spiral breakup during sustained fibrillation at different thermal states.
Temperature and nonlinear diffusion effects are found to impact the
repolarization phase of the action potential wave with non-monotone patterns
and to increase the propensity of arrhythmogenesis
Temperature dependence of the anomalous effective action of fermions in two and four dimensions
The temperature dependence of the anomalous sector of the effective action of
fermions coupled to external gauge and pseudo-scalar fields is computed at
leading order in an expansion in the number of Lorentz indices in two and four
dimensions. The calculation preserves chiral symmetry and confirms that a
temperature dependence is compatible with axial anomaly saturation. The result
checks soft-pions theorems at zero temperature as well as recent results in the
literature for the pionic decay amplitude into static photons in the chirally
symmetric phase. The case of chiral fermions is also considered.Comment: RevTex, 19 pages, no figures. References adde
Anomalous mesonic interactions near a chiral phase transition
Using constituent quarks coupled to a linear sigma model at nonzero
temperature, I show that many anomalous mesonic amplitudes, such as , vanish in a chirally symmetric phase. Processes
which are allowed, such as , are
computed to leading order in a loop expansion.Comment: 4 pages, REVTeX, submitted to Phys. Rev. Let
How pi0 -> gamma gamma changes with temperature
At zero temperature, in the chiral limit the amplitude for pi0 to decay into
two photons is directly related to the coefficient of the axial anomaly. At any
nonzero temperature, this direct relationship is lost: while the coefficient of
the axial anomaly is independent of temperature, in a thermal bath the
anomalous Ward identities do not uniquely constrain the amplitude for pi0 ->
gamma gamma. Explicit calculation shows that to lowest order about zero
temperature, this amplitude decreases.Comment: 12 pages, ReVTeX, 4 figures, to be published in Phys. Rev. D. New
section 5 with proof of the Adler-Bardeen theorem at low
Measurement of χ c1 and χ c2 production with s√ = 7 TeV pp collisions at ATLAS
The prompt and non-prompt production cross-sections for the χ c1 and χ c2 charmonium states are measured in pp collisions at s√ = 7 TeV with the ATLAS detector at the LHC using 4.5 fb−1 of integrated luminosity. The χ c states are reconstructed through the radiative decay χ c → J/ψγ (with J/ψ → μ + μ −) where photons are reconstructed from γ → e + e − conversions. The production rate of the χ c2 state relative to the χ c1 state is measured for prompt and non-prompt χ c as a function of J/ψ transverse momentum. The prompt χ c cross-sections are combined with existing measurements of prompt J/ψ production to derive the fraction of prompt J/ψ produced in feed-down from χ c decays. The fractions of χ c1 and χ c2 produced in b-hadron decays are also measured
Jet size dependence of single jet suppression in lead-lead collisions at sqrt(s(NN)) = 2.76 TeV with the ATLAS detector at the LHC
Measurements of inclusive jet suppression in heavy ion collisions at the LHC
provide direct sensitivity to the physics of jet quenching. In a sample of
lead-lead collisions at sqrt(s) = 2.76 TeV corresponding to an integrated
luminosity of approximately 7 inverse microbarns, ATLAS has measured jets with
a calorimeter over the pseudorapidity interval |eta| < 2.1 and over the
transverse momentum range 38 < pT < 210 GeV. Jets were reconstructed using the
anti-kt algorithm with values for the distance parameter that determines the
nominal jet radius of R = 0.2, 0.3, 0.4 and 0.5. The centrality dependence of
the jet yield is characterized by the jet "central-to-peripheral ratio," Rcp.
Jet production is found to be suppressed by approximately a factor of two in
the 10% most central collisions relative to peripheral collisions. Rcp varies
smoothly with centrality as characterized by the number of participating
nucleons. The observed suppression is only weakly dependent on jet radius and
transverse momentum. These results provide the first direct measurement of
inclusive jet suppression in heavy ion collisions and complement previous
measurements of dijet transverse energy imbalance at the LHC.Comment: 15 pages plus author list (30 pages total), 8 figures, 2 tables,
submitted to Physics Letters B. All figures including auxiliary figures are
available at
http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HION-2011-02
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