12 research outputs found
Effect of Raw and Extruded Propionic Acid-Treated Field Beans on Energy and Crude Protein Digestibility (In-Vitro and In-Vivo), Growth and Carcass Quality in Grow-Finisher Pigs
- Author
- Publication venue
- 'MDPI AG'
- Publication date
- 01/10/2021
- Field of study
The in-vitro ileal digestibility of dry matter (DM), organic matter (OM), and crude protein (CP) of field beans treated with propionic acid (trFB) and extruded trFB (exFB) was determined in experiment 1. The DE and dCP values of trFB and exFB were determined using the difference method in experiment 2. The effect of replacing SBM with trFB and exFB in grow-finisher diets on growth, carcass quality, apparent ileal digestibility (AiD), and total tract digestibility (ATTD) of DM, OM, gross energy (GE), and CP were investigated in experiment 3. In exp. 1, in-vitro digestibility of exFB compared to trFB was unchanged for DM (p = 0.12), increased for OM (p 0.05).info:eu-repo/semantics/publishedVersio
Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue
- Author
- Aguilar-Mogas Antoni
- Blüher Matthias
- Carracedo Álvarez Ángel
- Castaño Carlos
- Castellano Giancarlo
- Chapaprieta Vicente
- Claret i Carles Marc
- Dahdah Norma
- Duran Xavier
- Enriquez Jose Antonio
- Fernández Ruiz Rebeca
- Fernández-Veledo Sonia
- Gama-Perez Pau
- Garcia Roves Pablo M.
- Gomis Ramon, 1946-
- González Franquesa Alba
- Graupera i Garcia-Milà Mariona
- Guimerà Roger
- Herrero Laura
- Hoffman Anne
- Keller Markus A
- Kulis Marta
- Latorre Pellicer Ana
- Martín-Subero José Ignacio
- Miró-Blanch Joan
- Monelli Erika
- Monsalve Maria
- Montane Joel
- Moreno-Gomez Sonia
- Navarro Lourdes
- Nogueiras Rubén
- Novials Anna
- Obach Merce
- Oemer Gregor
- Perales Losa Carlos
- Prieto Ignacio
- Sales-Pardo Marta
- Samino Gené Sara
- Sanchez-Rebordelo Estrella
- Schneeberger Marc
- Soria Guadalupe
- Sun Wenfei
- Szczepanowska K.
- Trifunovic Aleksandra
- Vendrell Joan
- Wolfrum Christian
- Yanes Oscar
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Metabolic plasticity is the ability of a biological system to adapt its metabolic phenotype to different environmental stressors. We used a whole-body and tissue-specific phenotypic, functional, proteomic, metabolomic and transcriptomic approach to systematically assess metabolic plasticity in diet-induced obese mice after a combined nutritional and exercise intervention. Although most obesity and overnutrition-related pathological features were successfully reverted, we observed a high degree of metabolic dysfunction in visceral white adipose tissue, characterized by abnormal mitochondrial morphology and functionality. Despite two sequential therapeutic interventions and an apparent global healthy phenotype, obesity triggered a cascade of events in visceral adipose tissue progressing from mitochondrial metabolic and proteostatic alterations to widespread cellular stress, which compromises its biosynthetic and recycling capacity. In humans, weight loss after bariatric surgery showed a transcriptional signature in visceral adipose tissue similar to our mouse model of obesity reversion. Overall, our data indicate that obesity prompts a lasting metabolic fingerprint that leads to a progressive breakdown of metabolic plasticity in visceral adipose tissue
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.
- Author
- Ahern David J
- Ai Zhichao
- Ainsworth Mark
- Allan Chris
- Allcock Alice
- Angus Brian
- Ansari M Azim
- Arancibia-Carcamo Carolina V
- Aschenbrenner Dominik
- Attar Moustafa
- Baillie J Kenneth
- Barnes Eleanor
- Bashford-Rogers Rachael
- Bashyal Archana
- Beer Sally
- Berridge Georgina
- Beveridge Amy
- Bibi Sagida
- Bicanic Tihana
- Blackwell Luke
- Bowness Paul
- Brent Andrew
- Brown Andrew
- Broxholme John
- Buck David
- Burnham Katie L
- Byrne Helen
- Camara Susana
- Charles Philip
- Chen Wentao
- Chen Yi-Ling
- Chong Amanda
- Clutterbuck Elizabeth A
- Coles Mark
- Conlon Christopher P
- Cornall Richard
- Cribbs Adam P
- Curion Fabiola
- Davenport Emma E
- Davidson Neil
- Davis Simon
- Delgado Alberto Santos
- Dendrou Calliope A
- Dequaire Julie
- Dib Lea
- Docker James
- Dold Christina
- Dong Tao
- Downes Damien
- Drakesmith Hal
- Dunachie Susanna J
- Duncan David A
- Eijsbouts Chris
- Esnouf Robert
- Espinosa Alexis
- Etherington Rachel
- Fairfax Benjamin
- Fairhead Rory
- Fang Hai
- Fassih Shayan
- Felle Sally
- Ferreira Ivan Candido
- Ferreira Ricardo
- Fischer Roman
- Foord Thomas
- Forrow Aden
- Frater John
- Fries Anastasia
- Garner Lucy C
- Geeves Clementine
- Georgiou Dominique
- Godfrey Leila
- Golubchik Tanya
- Green Angie
- Harper Hong
- Harrington Heather A
- Heilig Raphael
- Hester Svenja
- Hill Jennifer
- Hinds Charles
- Hird Clare
- Ho Ling-Pei
- Hoekzema Renee
- Hollis Benjamin
- Hughes Jim
- Hutton Paula
- Jackson-Wood Matthew A
- Jainarayanan Ashwin
- James-Bott Anna
- Jansen Kathrin
- Jeffery Katie
- Jones Elizabeth
- Jostins Luke
- Karali Christina Simoglou
- Kerr Georgina
- Kim David
- Klenerman Paul
- Knight Julian C
- Kumar Vinod
- Kurupati Prathiba
- Kwok Andrew
- Lee Angela
- Linder Aline
- Lockett Teresa
- Lonie Lorne
- Lopopolo Maria
- Lukoseviciute Martyna
- Luo Jian
- Marinou Spyridoula
- Marsden Brian
- Martinez Jose
- Matthews Philippa C
- Mazurczyk Michalina
- McGowan Simon
- McKechnie Stuart
- Mead Adam
- Mendoza Maria Fernandez
- Mentzer Alexander J
- Mi Yuxin
- Monaco Claudia
- Montadon Ruddy
- Napolitani Giorgio
- Nassiri Isar
- Novak Alex
- O'Brien Darragh P
- O'Connor Daniel
- O'Donnell Denise
- Ogg Graham
- Overend Lauren
- Park Inhye
- Pavord Ian
- Peng Yanchun
- Penkava Frank
- Peres Raphael Sanches
- Perez Elena
- Pinho Mariana Pereira
- Pollard Andrew J
- Powrie Fiona
- Psaila Bethan
- Quan T Phuong
- Repapi Emmanouela
- Revale Santiago
- Rich-Griffin Charlotte
- Richard Jean-Baptiste
- Ritter Thomas
- Rollier Christine S
- Rowland Matthew
- Ruehle Fabian
- Salio Mariolina
- Sanchez Veronica Gallardo
- Sansom Stephen Nicholas
- Sauka-Spengler Tatjana
- Schwessinger Ron
- Scozzafava Giuseppe
- Screaton Gavin
- Seigal Anna
- Semple Malcolm G
- Sergeant Martin
- Sharma Piyush Kumar
- Silva-Reyes Laura
- Sims David
- Skelly Donal
- Slawinski Hubert
- Sobrinodiaz Alberto
- Sousos Nikolaos
- Stafford Lizzie
- Stockdale Lisa
- Strickland Marie
- Sumray Otto
- Sun Bo
- Taylor Adan
- Taylor Chelsea
- Taylor Stephen
- Thongjuea Supat
- Thraves Hannah
- Todd John A
- Tomic Adriana
- Tong Orion
- Trebes Amy
- Trzupek Dominik
- Tucci Felicia Anna
- Turtle Lance
- Udalova Irina
- Uhlig Holm
- van Grinsven Erinke
- Vazquez Maria Gomez
- Vendrell Iolanda
- Verheul Marije
- Voda Alexandru
- Wang Dapeng
- Wang Guanlin
- Wang Lihui
- Watkinson Peter
- Watson Robert
- Weinberger Michael
- Whalley Justin
- Witty Lorna
- Wray Katherine
- Xue Luzheng
- Yeung Hing Yuen
- Yin Zixi
- Young Rebecca K
- Youngs Jonathan
- Zhang Ping
- Zurke Yasemin-Xiomara
- Publication venue
- Elsevier
- Publication date
- 01/01/2021
- Field of study
Treatment of severe COVID-19 is currently limited by clinical heterogeneity and incomplete description of specific immune biomarkers. We present here a comprehensive multi-omic blood atlas for patients with varying COVID-19 severity in an integrated comparison with influenza and sepsis patients versus healthy volunteers. We identify immune signatures and correlates of host response. Hallmarks of disease severity involved cells, their inflammatory mediators and networks, including progenitor cells and specific myeloid and lymphocyte subsets, features of the immune repertoire, acute phase response, metabolism, and coagulation. Persisting immune activation involving AP-1/p38MAPK was a specific feature of COVID-19. The plasma proteome enabled sub-phenotyping into patient clusters, predictive of severity and outcome. Systems-based integrative analyses including tensor and matrix decomposition of all modalities revealed feature groupings linked with severity and specificity compared to influenza and sepsis. Our approach and blood atlas will support future drug development, clinical trial design, and personalized medicine approaches for COVID-19
Changes in Bone Mineral Density in Patients with Type 2 Diabetes After Different Bariatric Surgery Procedures and the Role of Gastrointestinal Hormones
- Author
- A Casajoana
- A Mieczkowska
- AG Pittas
- AH Maghrabi
- Anna Casajoana
- Anna Vidal-Alabró
- B Nuche-Berenguer
- B Nuche-Berenguer
- C Gagnon
- C Muschitz
- C Muschitz
- Carmen Gómez-Vaquero
- Carolina Alves
- CS Voican
- DB Henriksen
- EM Stein
- EW Yu
- F Carrasco
- Fernando Guerrero-Pérez
- G Maccarinelli
- I Kanazawa
- IP Wong
- JA Kanis
- Javier Osorio
- JB Buse
- JE Varela
- JH Wei
- JL Chan
- Joan Vendrell
- Jordi Pujol-Gebelli
- JS Walsh
- KK Ivaska
- Laura Hernández-Montoliu
- LR Madsen
- M Misra
- MA Karsdal
- Manuel Perez-Maraver
- MC Bunck
- MC Hsin
- MM Brzozowska
- MP Hage
- MR Crawford
- N Fukushima
- N Napoli
- N Vilarrasa
- Nuria Vilarrasa
- Nuria Virgili
- P Vestergaard
- PH Stern
- Rafael López-Urdiales
- Silvia Pellitero
- Sonia Fernández-Veledo
- TM Wolever
- X Nogués
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A multi-analytical characterization of artists’ carbon-based black pigments
- Author
- A Ciucci
- A Cuesta
- A Lluveras-Tenorio
- A Sadezky
- A Spepi
- A Van Loon
- A Vila
- Alessio Spepi
- Anna Lluveras-Tenorio
- Azzurra Milia
- C Duce
- C Duce
- C Duce
- C Roldán
- Celia Duce
- D Anglos
- D Anglos
- D Carbò
- D Li
- D Parras-Guijarro
- D Pellegrini
- D Tamburini
- DC Creagh
- DC Smith
- E Ebner
- E Tomasini
- EH Van’t Hul-Ehrnreich
- EP Tomasini
- F Tuinstra
- Giulia Lorenzetti
- HGM Edwards
- I Bonaduce
- ICA Sandu
- Ilaria Bonaduce
- J La Nasa
- J Rath
- J Van der Weerd
- J Winters
- JL Perez-Rodriguez
- JS Olin
- KL Rasmussen
- L Burgio
- L Burgio
- L Burgio
- L Ghezzi
- L Nikiel
- L Rampazzi
- M Calamitou
- M Castillejo
- M Corsi
- M Pawlyta
- M Tascon
- Maria Perla Colombini
- Maria Rosaria Tinè
- Marius Vendrell
- Matteo Pieraccioni
- MC Jimenez de Haro
- MD Gayo
- MR Tiné
- N Nakamizo
- O Beyssac
- RJ Stacey
- RL Farrow
- RM Silverstein
- S Dolci
- Stefano Legnaioli
- T Gatta
- T Jawhari
- TP Mernagh
- Vincenzo Palleschi
- Ž Dohnalová
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Potential role of glycosidase inhibitors in industrial biotechnological applications
- Author
- Alfonso Giovane
- Anna M Perez-Vendrell
- Balestrieri
- Bedford
- Bedford
- Bedford
- Bedford
- Beg
- Bhat
- Birte Svensson
- Bonnin
- Bowles
- Briggs
- Cach
- Campbell
- Castaldo
- Castaldo
- Castaldo
- Choct
- Choct
- Christophersen
- Clark
- Clarke
- Coote
- Courtin
- Courtin
- Courtin
- Crabb
- Crabb
- Daniella Bellincampi
- Dash
- De Lorenzo
- De Sio
- Dean
- Dean
- DeBaere
- Debyser
- Debyser
- Debyser
- Dominguez
- Ducroo
- Dörfer
- El-Rify
- Estelle Bonnin
- Feng
- Fengler
- Ferrari
- Franco
- Galbe
- Giesbert
- Glore
- Graham
- Grassin
- Ham
- Ham
- Hans Goesaert
- Harris
- Haskell
- Henrissat
- Henry
- Hillhorst
- Höhn
- Ingelbrecht
- Ishii
- Ishii
- Jan Delcour
- Jens Frisbæk Sørensen
- Joachim Brufau
- Jones
- Joslyn
- Kajava
- Karsten M Kragh
- Kataoka
- Klockiewicz
- Kuhad
- Kulp
- Laura Camardella
- Laurikainen
- Lee
- Ly-Nguyen
- Ly-Nguyen
- Ly-Nguyen
- Maat
- MacGregor
- MacGregor
- MacGregor
- MacGregor
- Macri
- Maga
- Mathlouthi
- Matthews
- McCleary
- McLauchlan
- McLauchlan
- Morgan
- Munck
- Mundy
- Nathalie Juge
- Ole Sibbesen
- Paice
- Patel
- Pettersson
- Pilnik
- Poutanen
- Powell
- Preston
- Pritchard
- Qin
- Rani
- Redgewell
- Renato D'Ovidio
- Rose
- Rouau
- Rouau
- Salobir
- Schoch
- Schols
- Schreier
- Schultz
- Silva
- Stotz
- Suurnäkki
- Sørensen
- Tariq A Tahir
- Tull
- Tull
- Täufel
- Van der Maarel
- Vickers
- Viikari
- Viëtor
- Vynck
- Ward
- Weegels
- Weselake
- Wong
- Wong
- Wu
- Würsch
- Yamasaki
- Yoshigi
- Zawastikowska
- Zetelaki-Horvath
- Zetelaki-Horvath
- Zobel
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Management practices for postdural puncture headache in obstetrics: a prospective, international, cohort study
- Author
- Aart-Jan Teunissen
- Adalbjörn Thorsteinsson
- Agnes Geertje Kuijpers-Visser
- Agnès Lecinq
- Aida Faria M.
- Alahuhta Seppo
- Alain Kalmar
- Alberto Martínez
- Aleksandra Bulasevic
- Aleksandra Jokic
- Ales Rozman
- Alessandro Zito
- Alexander Dullenkopf
- Alexander Ioscovich
- Alexandra Schyns-van den B.
- Amélia Ferreira
- Ana María Plaza M.
- Ana Jadrijevic
- Ana Milheiro
- Anastasia Loukeri
- Andrius Macas
- Anette Hein
- Anibal Ricardo Perez G.
- Anil Gupta
- Anja Lindén-Söndersö
- Anna Hellblom
- Anne Delmas
- Anne Mäyrä
- Anne-Sophie Bouthors
- Anouk van der Knijff
- Antonia Helf
- Antonia Stavrianopoulou
- Atara Davis
- Athanasia Tsaroucha
- Aurelie Courbon
- Ayca Tas T.
- Barbara Pesetti
- Bart Bryon
- Bartłomiej Wódarski
- Bastiaan Verdouw
- Beleña Jose M.
- Bernardo Matias
- Berrin Gunaydin D.
- Bijan Darvish
- Birgit Bette
- Bjoern Mygil
- Blažena Zaoralová
- Borislava Pujić
- Brigitte Storme
- Caridad Remacha G.
- Carl Tua
- Carla Bentes
- Carmen García-Cuadrado
- Carolina Cardoso
- Carolina Garcia B.
- Caroline van der Marel
- Catarina Sampaio A.
- Catherine Fischer
- Ceferina Suárez C.
- Charlotte Krebs Albrechtsen
- Christian Kufa
- Christian von Heymann
- Christina Froeslev-Friis
- Christine Pluymakers
- Christine Quintin
- Christoph Hoefing
- Chryssoula Staikou
- Clara Alamillo S.
- Claudia Neumann
- Claudia Vonlanthen
- Cláudia Castanheira
- Cristian Hernandez
- Cristiana Pereira
- Cristina Rodriguez R.
- Cristina Todde
- Damjan Marin
- De Joaquin Carlos-Errea
- De Maroto Pinar Santos
- Dick Cornelisse
- Diego Anta
- Dimitrios Valsamidis
- Dragan Graovac
- Eidelman Leonid A.
- Elena Suarez
- Elisabet Arbman
- Ellis Muggleton
- Else-Marie Ringvold
- Emilia Guasch A.
- Emmanuel Boselli
- Enric Moret
- Eric Koolen
- Estela Pereira
- Estíbaliz Bárcena
- Eva Roofthooft
- Evija Austruma
- Fabrizio Iannuccelli
- Fernando Gilsanz
- Fernando Iturri
- Fernando Moura
- Fernando Roshan
- Filiep Soetens
- Filipa Lança
- Fleur Meniolle d'Hauthville
- Florence Vial
- Francesco Vivaldi
- Francis Borg
- Francisca Tavares
- Francisco Gouveia
- Georges Savoldelli
- Geraldine Lambert
- Giorgio Della R.
- Glória Tareco
- Gordana Pavlovic
- Gorka Aldalur
- Grazia Frigo M.
- Grazina Keraitiene
- Gràcia Solsona Josep A.
- Gupta Anil
- Hawa Keita
- Heidrun Lewald
- Helena Hansson
- Henk Vanoverschelde
- Henning Ohnesorge
- Herminia Cabido
- Håkan Rolfsson
- Iacob Ramona
- Ilse Dons
- Ingrid Beenakkers
- Inês Furtado
- Irene Ferreira
- Irene Garcia
- Isabel Guedes-Araujo
- Isabelle Casier
- Iva Blajic
- Ivan Sklebar
- Ivana Volfová
- Jan Christiaen
- Jan Persson
- Jan Rosenberg
- Jana Simonova
- Jean Lutz
- Joana Teixeira
- Johan Forshammar
- Jose Luis Aguilar S.
- Josef Schaller S.
- Julia Herrera
- Julieta Latorre
- Karim Bouattour
- Karin Becke
- Karin Thorlacius
- Katarina Levin
- Kati Rautaneva
- Kestutis Rimaitis
- Kirsti Linden
- Konstantina Kalopita
- Kosinova Martina
- Lars Brühne
- Lars Gillberg
- Laura Ramió
- Laura Ricol
- Lauranne Osse
- Leire Martínez
- Leonor Veiga-Gil
- Lidija Jovanovic
- Lourdes Hernández G.
- Lourdes Trillo
- Luca Brazzi
- Lucindo Ormonde
- Luigi De S.
- Lutz Kaufner
- Luísa Marinho
- Magnuson Anders
- Malin Ugarph E.
- Manfred Blobner
- Manue Seabra
- Manuel Abecasis
- Manuel López-Baamonde
- Mara Cortez
- Marc Van de Velde
- Marco Aversano
- Maria Inmaculada Valldeperas H.
- Maria Soler P.
- Marie Barbier
- Marie-Pierre Bonnet
- Marija Kutlesic
- Marina Vendrell
- Marjolein Van den N.
- Markus Hollmann W.
- Marta Magaldi M.
- Martine Bonnin
- Mathieu Carbonniere
- Matthias Grünewald
- Maya Brunner
- Mercier Frédéric J.
- Michal Pelka
- Michela Camorcia
- Mickaël Soued
- Milan Adamus
- Minh Nguyen T.
- Miodrag Fhilipovic
- Miriam Neves
- Mirjana Kendrisic
- Moira Robertson (Baeriswyl)
- Monika Grochova
- Monika Tillenius
- Monique Bauters
- Morena Basso
- Natalia Sierra B.
- Naz Aslam T.
- Nele Ruysschaert
- Nordstöm Johan L.
- Ola Rosén
- Olivier Mascle
- Osvaldo Ceferino Pérez P.
- Pablo Monedero
- Paola-Carla Picard
- Paraskevi Matsota
- Patrick Van H.
- Paulo Lemos
- Paulo Muchacho
- Paulo Paredes
- Pedro Vasconcelos
- Pelin Corman D.
- Peter Bansch
- Peter Kranke
- Pia Auf der M.
- Pierre-Yves Dewandre
- Pierre-Édouard Greil
- Qamile Morina
- Radosław Chutkowski
- Radovan Wiszt
- Raquel Sánchez N.
- Raquel Tranquada
- Reidar Eriksen J.
- Riad Tome
- Rita Araujo
- Robert Hagen
- Roel Schepers
- Roque Guillén-Casbas
- Rosa Serna
- Rosario Fortuna
- Ruaa Al-Taie
- Sabine Welfle
- Sandra Pereira
- Sara Toivakka
- Sarah Devroe
- Schyns-van den Berg Alexandra M.J.V.
- Seppe Koopman
- Seppo Alahuhta
- Sharon Orbach-Zinger
- Slobodan Mihaljević
- Sofus Rabow
- Sophie Nebout
- Stanislas Mathivon
- Stefan Mueller
- Stefan Weber
- Stourac Petr
- Sule Ozbilgin
- Susana Manrique
- Susanna Mennander
- Susanne Ledin-Eriksson
- Tarik Hlioua
- Tatjana Stopar P.
- Teresa Chiquito
- Thierry Girard
- Thomas Detente
- Thérèse Simonet
- Tijs Van den B.
- Tomasz Skirecki
- Tomi Kavasmaa
- Tuula Hiekkanen
- Ulrike Stamer
- Van de Velde Marc
- van Nick Dasselaar
- Vegard Dahl
- Vesa Kontinen
- Vitor Pinho-Oliveira
- von Heymann Christian
- Vânia Pacheco
- Yvonne Jelting
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/12/2020
- Field of study
© 2020 British Journal of AnaesthesiaBackground: Accidental dural puncture is an uncommon complication of epidural analgesia and can cause postdural puncture headache (PDPH). We aimed to describe management practices and outcomes after PDPH treated by epidural blood patch (EBP) or no EBP. Methods: Following ethics committee approval, patients who developed PDPH after accidental dural puncture were recruited from participating countries and divided into two groups, those receiving EBP or no EBP. Data registered included patient and procedure characteristics, headache symptoms and intensity, management practices, and complications. Follow-up was at 3 months. Results: A total of 1001 patients from 24 countries were included, of which 647 (64.6%) received an EBP and 354 (35.4%) did not receive an EBP (no-EBP). Higher initial headache intensity was associated with greater use of EBP, odds ratio 1.29 (95% confidence interval 1.19–1.41) per pain intensity unit increase. Headache intensity declined sharply at 4 h after EBP and 127 (19.3%) patients received a second EBP. On average, no or mild headache (numeric rating score≤3) was observed 7 days after diagnosis. Intracranial bleeding was diagnosed in three patients (0.46%), and backache, headache, and analgesic use were more common at 3 months in the EBP group. Conclusions: Management practices vary between countries, but EBP was more often used in patients with greater initial headache intensity. EBP reduced headache intensity quickly, but about 20% of patients needed a second EBP. After 7 days, most patients had no or mild headache. Backache, headache, and analgesic use were more common at 3 months in patients receiving an EBP
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- Abbot C. C.
- Abhandl
- Abhandlungen des Instituts H.
- Abont E.
- Abont E.
- Abont E.
- Abry E.
- Ac
- Acad
- Ackermann
- Acta Reg
- Acuna Hernando J. M.
- Ad
- Ad
- Adam
- Adam J. J.
- Adams N. B.
- Adamsspiel
- Adamsspiel H.
- Addonizzo F.
- Adefonsus
- Adenet Ph. A.
- Adriäo J. M.
- Ae
- Aebischer P.
- Agostinho J.
- Aguirre Matias H.
- Agustin F.
- Aiiguita E
- Aimon de Varennes
- Aires
- Aita A.
- Aita A.
- Aita A.
- Alain Chartier
- Alain E.
- Alain E.
- Alberic de Besannen
- Albina Romäneascä
- Alcalä Zamora
- Alcoforado Mariana A.
- Alcoforado Mariana A.
- Alcover A. M.
- Alcover Antoni F.
- Aldana Cosme J. P. W.
- Aldana Francisco J.M.
- Alds-Moner
- Alembert J.
- Alexander R. S
- Alexandrina
- Aley K.
- Alfieri V. E.
- Alfonso X
- Alfonso X
- Algumas
- Alia A.
- Aliflunatm H. P. J. M.
- Aliscans C.
- Allemagne H. R.
- Almeida Antonio P. W.
- Almeras H.
- Alonso de Santa Cruz B.
- Alonso Dämaso
- Alonso Fernandez
- Alos-Moner R.
- Alpers P.
- Als Sonderdr S.
- Altamira R.
- Altamirano A. I.
- Altmann J. B.
- Alton J. F.
- Altschul A.
- Altschul A.
- Altucci C.
- Alvarez Gato Juan
- Alvarez Limeeee G.
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- Amat Calderon Elena
- Amatucci A. G.
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- Ampere J.
- Amrein-Widmer M.
- Amtchkof E.
- Amyot P.
- Am£ de Montgesoie Th.
- Anagnine E.
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- Angela Hämel-Stier
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- Gioacchino da Fiore E
- Gioberti V. S
- Giordani P. G.
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- Giovanni A.
- Giraldi G. B. G
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- Girard P.
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- Gobineau J.
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- Gongora Luis B.
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- Gracian Baltasar V.
- Graciän Baltasar V
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- Gral M.
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- Grand Flurin S.
- Grannig V. B.
- Grassilier
- Grautoff O.
- Grecu V.
- Green F.
- Green F. C.
- Green M.
- Green O. H.
- Grelan Arnoul R.
- Grevin J. F
- Griffith D. D.
- Grillet C.
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- Grosclaude P.
- Grosclaude P.
- Grossmann R.
- Grossmann R.
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- Grpult P.
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- Guillaume F
- Guillem de Cervera M.
- Guimerä Angel
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- Guittone F.
- Gurian W.
- Gurian W.
- Gutierrez Juan Maria J. M.
- Gutkind
- Gutkind C. S.
- Guyer Foster E.
- Gäzdaru D.
- Göhring M.
- Güllecke K.
- Habert F. H
- Hagen H. B.
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- Hainlein G.
- Hainlein G.
- Hainsworth G.
- Hainsworth G.
- Hajdn H.
- Halle
- Halle
- Haller J.
- Halphen L.
- Hamann R.
- Hamburger Studien S
- Hamilton G. H.
- Hamilton G. H.
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- Handbuch der Spanienkunde H.
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- Harding J. D.
- Harmand R.
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- Hatzfeld H.
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- Hatzfeld H.
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- Haupt A.
- Hautes Istudes
- Hauvette H.
- Hauyette H.
- Havens N. L.
- Hazard
- Hazard P.
- Hazard P.
- Hazard P.
- Hazard P.
- Hazard P.
- Hebe H.
- Heeter H.
- Hegesippi V
- Heiin M.
- Heiinant de Froidmont
- Heiss H.
- Heiss H.
- Heist W.
- Heldris de Cornualle H.
- Heller B.
- Helm
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- Hemnann A.
- Hendrix W. S.
- Heniicns Septimellensis K
- Henriot E.
- Henriot E.
- Henriquez Urena P.
- Henriquez Urena P.
- Herbst J.
- Herculano Alexandre A.
- Heredia J.
- Herelle G.
- Hero
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- Herrero Garcia M.
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- Hespelt
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- Hietoria G. L.
- Hiiysmans J.
- Hiiysmans J.
- Hiiysmans J.
- Hilarius Piclavensis W. N.
- Hilka
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- Hilton R.
- Hintze H.
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- Hippel E.
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- Hisp
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- Histoireancienne J
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- Historia
- Hndal A.
- Hobohm F.
- Hobohm F.
- Hofmeister Ph
- Holbrook A
- Holbrook A
- Holmes R. E. V.
- Holsboer I. W.
- Hoppe K.
- Horawski J.
- Hotman Fr J. C
- Howald E.
- Howald E.
- Hudson Margaret E.
- Hugo V. A
- Hugo V. K.
- Hugo V. K.
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- Hugo V. K.
- Hugo V. K.
- Hugo V. K.
- Hugo V. K.
- Hugo V. K.
- Hung Cheng Fu
- Hunt C.
- Hurtado de Mendoza J. P. W
- Huyemans J.
- Hyslop B. F.
- Hämel A.
- Hämel A.
- Hämel A.
- Hämel A.
- Hämel A.
- Hämel A.
- Högberg P.
- Högberg P.
- Ibräileaau G.
- Idem
- In
- In
- In
- In
- In
- In
- In
- In
- In
- In
- In
- In
- In
- In
- In
- In
- In
- In
- In
- In
- In
- In 0
- In An
- In An
- In Cy
- In Festgabe M.
- In Festgabe M.
- In Gsliioo
- In I
- In Merc
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- In Rpl
- In Sfi
- In VI
- In VI
- In VI
- In Wechssler-Festschriff
- In Zf
- In £tudes Th
- Index R.
- Ines de Castro-Thema M.
- Infanten von Lara J. O.
- Inhalt
- Institutul
- Iraizoz A.
- Iriarte M.
- Iridorue τοη Sevilla J.
- Isaza
- Isidorus von Sevilla J.
- Italia
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- Ith Century Tragedy
- Ithier J. J. W.
- Itscr
- Itscr
- Itscr
- Itscr
- Itscr 0
- Itscri
- Itscri S
- Itscris
- Ivanoff N.
- Jacob E. G.
- Jacob L.
- Jacoubet H.
- Jacoubet H.
- Jacoubet H.
- Jacoubet H.
- Jacoubet H.
- Jaeger H.
- Jaeger H.
- Jaesemin H.
- Jameeon R. D.
- Jamyn A
- Jan E
- Jan E.
- Jan E. v.
- Janme I
- Janry P.
- Jarcho B. J.
- Jarnström E
- Jarry A. P
- Jasinski R.
- Jasmin J.
- Jean
- Jean Bodel C. E
- Jean de Conde L.
- Jean de la Chapele
- Jean le Maure
- Jean Renart J.
- Jeanroy
- Jeanroy
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- Jeanroy
- Jeanroy A.
- Jeanroy A.
- Jeanroy A.
- Jeffery V. M.
- Jimenez de Rada R.
- Jimenez Rueda J.
- Jimenez Salas Maria
- Jinnouneky M.M.
- Jnnghans F.
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- John Pecknam A.
- Joinville
- Jollivet G.
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- Jones P. J.
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- Jones W. P.
- Jones W. P.
- Jordan L.
- Jordan L.
- Jordi des Reco A. M.
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- Jourda
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- Jouvene H
- Joäo
- Juan Manuel
- Juan Manuel
- Juan Manuel A.
- Julia E.
- Julia Martinez E.
- Jung C. G.
- Jungandreas W.
- Jäckel K.
- Jäger
- Kagarov E.
- Kainz F.
- Kalepky T.
- Kampere F.
- Kantorowicz E.
- Kantorowicz H.
- Karl
- Karl L.
- Karl L.
- Karl L.
- Kasper E.
- Katalanische Übersetzung 0
- Katann
- Katann O.
- Katzenellenbogen L.
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- Kellermann
- Keniston H.
- Kennard J. S.
- Kentenich G.
- Ketrick P. J.
- Key de Artieda E.
- Keyserling H.
- Kichert Gertrud
- Kienast W.
- Kiepert A.
- Kindermann H.
- King D. L.
- Kinkel H.
- Klaiber L.
- Klein K.
- Klein K.
- Klemperer
- Klemperer
- Klemperer V.
- Klemperer V.
- Klemperer V.
- Klemperer V.
- Klemperer V.
- Kluge O.
- Knapp F.
- Knauer K.
- Knowles D.
- Knudson 0
- Kogälniceann M.
- Kol
- Kolb-Danvin
- Kolbenheyer E. G.
- Kolsen
- Kolter G.
- Kommentar S
- Krakowski E.
- Krappe A. H.
- Krappe A. H.
- Krappe A. H.
- Krappe A. H.
- Krappe A. H.
- Krappe A. H.
- Krappe A. H.
- Krause W.
- Krauss W.
- Krieger H.
- Krogmann W.
- Kromer Helene
- Krüger
- Krüger
- Kube K. H.
- Kultur
- Kulturgeschichte des Mittelalters
- Kunath M.
- Kunstwerks
- Kupfer G.
- Kurfess A.
- Kuttner M.
- Kuttner M.
- Kölner Komanistische Arbeiten S
- Kölner Romanist
- Kölner S
- König R.
- Königl
- Königsberger Gelehrten Gesellschaft
- Küchler
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- L'Abbaye
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- La
- La
- La
- La
- La
- La
- La
- La
- La Beaumelle L
- La Boetie
- La Boetie
- La Borderie Ch. H.
- La Fontaine J.
- La Grans Freiere Nostre
- La Mothe F. A. L.
- La Passion
- La Renaissance I.
- La Rochefoucauld F
- La Rochefoucauld F
- La Rochefoucauld F.
- La Taille J.
- Laborde E. D.
- Lacalle A.
- Laclos P
- Lacoste V. B
- Lafora G. R.
- Lalou R.
- Lamartine A.
- Lamartine A.
- Lamennais F.
- Lamennais J.
- Lancelot M.
- Lanckoronska M.
- Lang A.
- Langen G.
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- Langue
- Langue
- Lanocita
- Lanson G.
- Lanson G.
- Lanzoni F.
- Lapcevic D.
- Larbaud V.
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- Larnac J.
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- Larra Mariano Jos£
- Larwill P. H.
- Lasborde H.
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- Lassus J.
- Latouche R.
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- Lazarillo de Tormes
- Lazo R.
- Lchmann P.
- Le
- Le
- Le Bau G.
- Le Cardonnel L. A.
- Le Cardonnel L. A.
- Le Charroi Hs. D
- Le Gentil
- Le Gentil
- Le Gentü
- Le Goffic Ch A.
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- Le Sage A.
- Le Sage A.
- Le Sage A.
- Leavitt S. E.
- Lebel R.
- Lefevre F.
- Legendre M.
- Legendre M.
- Legendre M.
- Lehmann P.
- Lehmann-Nitsehe R.
- Leicht P. S.
- Leii-ProYeiical E.
- Leite de Vasconcellos J.
- Leite deVasconcellos J.
- Lemaitre J. G.
- Lemonnier C. G.
- Lenoir
- Lenz
- Leon Mera Juan I. J.
- Leon Ricardo R.
- Leonard
- Leonard A
- Leonard I.A.
- Leonardo da Vinci F. M.
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- Leopardi G. G.
- Leopolde Alas W.
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- Lerch E.
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- Les Classiques
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- Levi A.
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- Levy R.
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- Lewis C. B.
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- Libro
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- Lncanus J.
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- Lnll Ramon T.
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- Lo Gatto E.
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- Loiseau H.
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- Lopez Maldonado
- Lopo
- Lorentowicz J
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- Los Clasicos Olvidados S
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- Lot F.
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- Loti P.
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- Lucidario J.
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- Längfors A.
- Löpelmann M.
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- Lösch
- Lützeler H.
- Maack R.
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- Macdonald I. L
- Machado de Silva Felix
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- Machiavelli N. A.
- MacPherson H. D.
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- Masini O.
- Masso J.
- Masso J.
- Masso J.
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- Matulka B.
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- Mauriac F.
- Mauriac F.
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- Mavnial E.
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- Mazzini G. G. E.
- Mazzoni
- Mazzoni G.
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- Merimee H.
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- Mittel der Spannung
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- Moeckli-Cellier M.
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- Moffat M.
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- Moldenhauer
- Moldenhauer G
- Moldenhauer G.
- Moldenhauer G.
- Molina
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- Molina Luis J.
- Molinet Jean Ph. A.
- Molins de Rei D.
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- Μέήηιέβ
- Οέηίβ de Rimbaud
- Οέηίβ de Rimbaud
- €irart de RoussUlon
- Publication venue
- 'Walter de Gruyter GmbH'
- Publication date
- 01/01/1938
- Field of study
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
- Author
- Aanei Carmen M.
- Abid Muhammad Bilal
- Abramowitz Matthew K.
- Abu-Zaid Ahmed
- Adamo Vincenzo
- Adeyemo Adebolajo A.
- Afnan Masoud
- Agarabi Cyrus
- Aggelidou Maria
- Ahmad Haroon
- Ahmad Rafi
- Aizat Wan M.
- Ajani Penelope A.
- Akinwumi Sayo A.
- Al-Farha Abd A.
- Al-Lawama Manar
- Al-Owaifeer Adi M.
- Al-Riyami Arwa Z.
- Alanio Alexandre
- Alaux Cedric
- Albery Gregory F.
- Albiol Joan
- Albrecht Dirk R.
- Albuquerque Lucia G.
- Alhowimel Ahmed
- Ali Junaid
- Alimba C. G.
- Allardyce Judith
- Almeida Gabriel M. F.
- Alonso-Caneiro David
- Alper Ozgul M.
- Alshehri Mansour
- Alsuhaibani Mohammed
- Alzghari Saeed K.
- Amer Said E. D. R.
- Amiya Eisuke
- Ammerman Brooke A.
- Amorim Rogerio M.
- An Qianli
- Anazodo Udunna C.
- Andersen Stig U.
- Andersen Vibeke
- Angus Kathryn
- Anikin Andrey
- Aplin John D.
- Argyropoulos Christos
- Armitage Charles
- Asaduzzaman Muhammad
- Asady Hadi
- Ascher David B.
- Asefa N. G.
- Ashry Mohamed
- Asmann Yan W.
- Assaeed Abdulaziz M.
- Atack John M.
- Atanasov Atanas G.
- Atchison David A.
- Atkins Gerald J.
- Atlas Lauren
- Ato Dai
- Avery Simon V.
- Avillach Paul
- Azubuike Samuel O.
- Baade Peter D.
- Bach-Mortensen Anders
- Backman Lars
- Badie Christophe
- Bae Taeok
- Bagloee Saeed A.
- Bai Xiaoyong
- Baier Dirk
- Bail Kasia
- Baines Rebecca L.
- Baker Chris I.
- Bakkach Joaira
- Baldi Alfonso
- Ball Elizabeth
- Ballantyne Maghan
- Baltiansky Lior
- Ban Bo
- Bannon Ross
- Bansal Abhisheka
- Bar Ido
- Bardot Olivier
- Barnett Adrian G.
- Barraud Pierre
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- Benezeth Yannick
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- Casillas Sonia
- Castelvetro Valter
- Caswell Patrick T.
- Catry Thibault
- Cavalli Giacomo
- Cernava Tomislav
- Cerovsky Vaclav
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- Chakraborty Sayan
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- Chen Huaming
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- Dao Myriam
- Darras Sebastien
- Dauga Delphine
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- Eerola Tuomas
- Effiong Andem
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- Eisenhardt Steffen
- Eixarch Elisenda
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- Elkum Naser
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- Epp Trevor
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- Galimov Evgeny
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- Guisado J. L.
- Gumede Nicksy
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- Yadollahpour Ali
- Yalcin Suayib
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- Yang Shiqi
- Yang Sunny Y.
- Yang Wei
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- Yankilevich Patricio
- Yao Ruifeng
- Yao Wen
- Yassine Abdul-Amir
- Ye Yuzhen
- Ye Zhi-Qiang
- Yeung Andy W. K.
- Yin Cong-Cong
- Yin Qinan
- Yli-Kauhaluoma Jari
- Yoneyama Hiroshi
- Yoon Jihoon G.
- You Yuyi
- Yousefzadeh Abbas
- Yu Chenglong
- Yu Ying
- Yu Yongbo
- Yuan Christina M.
- Yuan Guo-Cheng
- Yuh Chiou-Hwa
- Zabetakis Ioannis
- Zaccolo Manuela
- Zaitsu Masayoshi
- Zare Asma
- Zaritsky Arno
- Zaucha Jan
- Zeineb Zian
- Zeng Chen
- Zeng Erliang
- Zeng Zhen
- Zevnik Branko
- Zhan Jian
- Zhan Xiao-Yong
- Zhang Chengrong
- Zhang Chi
- Zhang Chongxing
- Zhang Gong
- Zhang Haowen
- Zhang Jilei
- Zhang Junpeng
- Zhang Kai
- Zhang Li
- Zhang Linxing
- Zhang Rongqiang
- Zhang Tongchuan
- Zhang Tuo
- Zhang Wei
- Zhang Weijia
- Zhang Xianglilan
- Zhang Xiaolei
- Zhang Yao
- Zhang Yi
- Zhang Yingkai
- Zhang Yusen
- Zhang Zhe
- Zhang Zhiyong
- Zhang Zhong-Yin
- Zhang Zhongheng
- Zhao Guoyan
- Zhao Haochen
- Zhao Jing
- Zhao Xin
- Zhao Yuan
- Zheng Shan
- Zhou Bailing
- Zhou Jianyu
- Zhou Kai
- Zhou Min
- Zhou Xiaofan
- Zhou Xiaoyan
- Zhou Yaoqi
- Zhu Dongjie
- Zhu Shu
- Zhu Zhenxing
- Ziegler Andreas
- Zinke Katharina
- Zuberbier Torsten
- Zuckerman Hannah
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Management practices for postdural puncture headache in obstetrics : a prospective, international, cohort study
- Author
- Abecasis Manuel
- Adamus Milan
- Aguilar Sanchez Jose Luis
- Al-Taie Ruaa
- Alahuhta Seppo
- Alahuhta Seppo
- Alamillo Salas Clara
- Aldalur Gorka
- Anta Diego
- Araujo Rita
- Arbman Elisabet
- Aslam Tayyaba Naz
- Auf der Maur Pia
- Austruma Evija
- Aversano Marco
- Bansch Peter
- Barbier Marie
- Basso Morena
- Bauters Monique
- Becke Karin
- Beenakkers Ingrid
- Beleña Jose M.
- Bentes Carla
- Bette Birgit
- Blajic Iva
- Blobner Manfred
- Bonnet Marie-Pierre
- Bonnin Martine
- Borg Francis
- Boselli Emmanuel
- Bouattour Karim
- Bouthors Anne-Sophie
- Brazzi Luca
- Brunner Maya
- Bryon Bart
- Brühne Lars
- Bulasevic Aleksandra
- Bárcena Estíbaliz
- Cabido Herminia
- Camorcia Michela
- Carbonniere Mathieu
- Cardoso Carolina
- Carlos-Errea De Joaquin
- Casier Isabelle
- Castanheira Cláudia
- Chiquito Teresa
- Christiaen Jan
- Chutkowski Radosław
- Corman Dincer Pelin
- Cornelisse Dick
- Cortez Mara
- Courbon Aurelie
- Dahl Vegard
- Darvish Bijan
- Davis Atara
- De Santos Maroto Pinar
- De Simone Luigi
- Della Rocca Giorgio
- Delmas Anne
- Detente Thomas
- Devroe Sarah
- Dewandre Pierre-Yves
- Dons Ilse
- Dullenkopf Alexander
- Eidelman Leonid A.
- Eriksen John Reidar
- Faria Maria Aida
- Fernando Roshan
- Ferreira Amélia
- Ferreira Irene
- Filipovic Miodrag
- Fischer Catherine
- Forshammar Johan
- Fortuna Rosario
- Frigo Maria Grazia
- Froeslev-Friis Christina
- Furtado Inês
- Garcia Bartolo Carolina
- Garcia Irene
- García-Cuadrado Carmen
- Gillberg Lars
- Gilsanz Fernando
- Girard Thierry
- Gouveia Francisco
- Graovac Dragan
- Greil Pierre-Édouard
- Grochova Monika
- Gràcia Solsona Josep A.
- Grünewald Matthias
- Guasch Arevalo Emilia
- Guedes-Araujo Isabel
- Guillén-Casbas Roque
- Gunaydin D Berrin
- Gupta Anil
- Gupta Anil
- Hagen Robert
- Hansson Helena
- Hein Anette
- Helf Antonia
- Hellblom Anna
- Hernandez Cristian
- Hernández González Lourdes
- Herrera Julia
- Hiekkanen Tuula
- Hlioua Tarik
- Hoefing Christoph
- Hollmann Markus W.
- Iannuccelli Fabrizio
- Ioscovich Alexander
- Iturri Fernando
- Jadrijevic Ana
- Jelting Yvonne
- Jokic Aleksandra
- Jovanovic Lidija
- Kalmar Alain
- Kalopita Konstantina
- Kaufner Lutz
- Kavasmaa Tomi
- Keita Hawa
- Kendrisic Mirjana
- Keraitiene Grazina
- Kontinen Vesa
- Koolen Eric
- Koopman Seppe
- Kosinova Martina
- Kranke Peter
- Krebs Albrechtsen Charlotte
- Kufa Christian
- Kuijpers-Visser Agnes Geertje
- Kutlesic Marija
- Lambert Geraldine
- Lança Filipa
- Latorre Julieta
- Lecinq Agnès
- Ledin-Eriksson Susanne
- Lemos Paulo
- Levin Katarina
- Lewald Heidrun
- Linden Kirsti
- Lindén-Söndersö Anja
- Loukeri Anastasia
- Lutz Jean
- López-Baamonde Manuel
- Macas Andrius
- Magaldi Mendaña Marta
- Magnuson Anders
- Manrique Susana
- Marin Damjan
- Marinho Luísa
- Martínez Alberto
- Martínez Leire
- Mascle Olivier
- Mathivon Stanislas
- Matias Bernardo
- Matsota Paraskevi
- Meniolle d’Hauthville Fleur
- Mennander Susanna
- Mercier Frédéric J.
- Mihaljević Slobodan
- Milheiro Ana
- Monedero Pablo
- Moret Enric
- Morina Qamile
- Moura Fernando
- Muchacho Paulo
- Mueller Stefan
- Muggleton Ellis
- Mygil Bjoern
- Mäyrä Anne
- Nebout Sophie
- Neumann Claudia
- Neves Miriam
- Nguyen Troung Minh
- Nordstöm Johan L.
- Ohnesorge Henning
- Orbach-Zinger Sharon
- Ormonde Lucindo
- Osse Lauranne
- Ozbilgin Sule
- Pacheco Vânia
- Paredes Paulo
- Pavlovic Gordana
- Pelka Michal
- Pereira Cristiana
- Pereira Estela
- Pereira Sandra
- Perez Garcia Anibal Ricardo
- Persson Jan
- Pesetti Barbara
- Picard Paola-Carla
- Pinho-Oliveira Vitor
- Plaza Moral Ana María
- Pluymakers Christine
- Pujić Borislava
- Pérez Pardo Osvaldo Ceferino
- Quintin Christine
- Rabow Sofus
- Ramió Laura
- Ramona Iacob
- Rautaneva Kati
- Remacha González Caridad
- Ricol Laura
- Rimaitis Kestutis
- Ringvold Else-Marie
- Robertson (Baeriswyl) Moira
- Rodriguez Roca Cristina
- Rolfsson Håkan
- Roofthooft Eva
- Rosenberg Jan
- Rosén Ola
- Rozman Ales
- Ruysschaert Nele
- Sampaio Ana Catarina
- Savoldelli Georges
- Schaller Stefan Josef
- Schepers Roel
- Schyns-van den Berg Alexandra
- Schyns-van den Berg Alexandra M.J.V.
- Seabra Manue
- Serna Rosa
- Sierra Biddle Natalia
- Simonet Thérèse
- Simonova Jana
- Skirecki Tomasz
- Sklebar Ivan
- Soetens Filiep
- Soler Pedrola Maria
- Soued Mickaël
- Staikou Chryssoula
- Stamer Ulrike
- Stavrianopoulou Antonia
- Stopar Pintraic Tatjana
- Storme Brigitte
- Stourac Petr
- Suarez Elena
- Suárez Cendaña Ceferina
- Sánchez Nuez Raquel
- Tareco Glória
- Tas Tuna Ayca
- Tavares Francisca
- Teixeira Joana
- Teunissen Aart-Jan
- Thorlacius Karin
- Thorsteinsson Adalbjörn
- Tillenius Monika
- Todde Cristina
- Toivakka Sara
- Tome Riad
- Tranquada Raquel
- Trillo Lourdes
- Tsaroucha Athanasia
- Tua Carl
- Ugarph Edfeldt Malin
- Valldeperas Hernandez Maria Inmaculada
- Valsamidis Dimitrios
- van Dasselaar Nick
- Van de Velde Marc
- Van de Velde Marc
- Van den Berg Tijs
- van der Knijff Anouk
- van der Marel Caroline
- Van Houwe Patrick
- Vanoverschelde Henk
- Vasconcelos Pedro
- Veiga-Gil Leonor
- Vendrell Marina
- Verdouw Bastiaan
- Vial Florence
- Vivaldi Francesco
- Volfová Ivana
- von Heymann Christian
- von Heymann Christian
- Vonlanthen Claudia
- Weber Stefan
- Welfle Sabine
- Wiszt Radovan
- Wódarski Bartłomiej
- Zaoralová Blažena
- Zito Alessandro
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
Background: Accidental dural puncture is an uncommon complication of epidural analgesia and can cause postdural puncture headache (PDPH). We aimed to describe management practices and outcomes after PDPH treated by epidural blood patch (EBP) or no EBP.
Methods: Following ethics committee approval, patients who developed PDPH after accidental dural puncture were recruited from participating countries and divided into two groups, those receiving EBP or no EBP. Data registered included patient and procedure characteristics, headache symptoms and intensity, management practices, and complications. Follow-up was at 3 months.
Results: A total of 1001 patients from 24 countries were included, of which 647 (64.6%) received an EBP and 354 (35.4%) did not receive an EBP (no-EBP). Higher initial headache intensity was associated with greater use of EBP, odds ratio 1.29 (95% confidence interval 1.19-1.41) per pain intensity unit increase. Headache intensity declined sharply at 4 h after EBP and 127 (19.3%) patients received a second EBP. On average, no or mild headache (numeric rating score <= 3) was observed 7 days after diagnosis. Intracranial bleeding was diagnosed in three patients (0.46%), and backache, headache, and analgesic use were more common at 3 months in the EBP group.
Conclusions: Management practices vary between countries, but EBP was more often used in patients with greater initial headache intensity. EBP reduced headache intensity quickly, but about 20% of patients needed a second EBP. After 7 days, most patients had no or mild headache. Backache, headache, and analgesic use were more common at 3 months in patients receiving an EBP