234 research outputs found
Effects of selected food phytochemicals in reducing the toxic actions of TCDD and p,p′-DDT in U937 macrophages
- Author
- A Murakami
- A Murakami
- A Murakami
- A Murakami
- Akira Murakami
- B Dong
- C Cuccurullo
- C Vogel
- CF Vogel
- CF Vogel
- CF Vogel
- CF Vogel
- Christoph F. Vogel
- Dalei Wu
- DE Frigo
- EM Sciullo
- Eric M. Sciullo
- EV Younglai
- F Soltani
- Fumio Matsumura
- GD Charles
- H Ashida
- Hajime Ohigashi
- HW Kim
- IL Jackson
- IN Perez-Maldonado
- K Komura
- M Lappas
- M Shibuya
- MA Altinoz
- MJ Taylor
- N Nishimura
- O Hankinson
- R Dutta
- S Park
- S Rozen
- S Zhang
- SA Kraemer
- T Tanaka
- T Tanaka
- Y Inoue
- Y Matsunaga
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2010
- Field of study
To assess the effectiveness of selected food phytochemicals in reducing the toxic effects of the environmental toxicants, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and p,p′-DDT (DDT), we tested the potencies of auraptene, nobiletin, zerumbone, and (±)-13-hydroxy-10-oxo-trans-11-octadecenoic acid (13-HOA) in reversing the inflammatory action of these toxicants in U937 human macrophages. Using quantitative RT–PCR as the initial screening assay, we identified antagonistic actions of zerumbone and auraptene against the action of TCDD and DDT in up-regulating the mRNA expressions of COX-2 and VEGF. The functional significance of the inhibitory action of zerumbone on COX-2 expression was confirmed by demonstrating its suppression of TCDD-induced activation of COX-2 gene expression in mouse MMDD1 cells. We tested auraptene on DDT-induced reactive oxygen species (ROS) formation in U937 macrophages and found that auraptene is a powerful agent antagonizing this action of DDT. To confirm the significance of these actions of zerumbone and auraptene at the cellular level, we assessed their influence on TCDD-induced apoptosis resistance in intact U937 macrophages and found that they are capable of reversing this action of TCDD. In conclusion, zerumbone and auraptene were identified to be the most effective agents in protecting U937 macrophages from developing these cell toxic effects of TCDD and DDT
Azimuthal anisotropy of charged jet production in root s(NN)=2.76 TeV Pb-Pb collisions
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aiola Salvatore
- Akindinov Alexander
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alfaro Molina Jose Ruben
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski Jonas
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Arnaldi Roberta
- Arnold Oliver Werner
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Baldisseri Alberto
- Baral Rama Chandra
- Barbano Anastasia Maria
- Barbera Roberto
- Barile Francesco
- Barnafoldi Gergely Gabor
- Barnby Lee Stuart
- Bartalini Paolo
- Barth Klaus
- Bartke Jerzy Gustaw
- Bartsch Esther
- Bashir Butt Jamila
- Basile Maurizio
- Bastid Nicole
- Basu Sumit
- Bathen Bastian
- Batigne Guillaume
- Batista Camejo Arianna
- Batyunya Boris
- Batzing Paul Christoph
- Bearden Ian Gardner
- Beck Hans
- Bedda Cristina
- Behera Nirbhay Kumar
- Belikov Iouri
- Bellini Francesca
- Bello Martinez Hector
- Bellwied Rene
- Belmont Iii Ronald John
- Belmont Moreno Ernesto
- Belyaev Vladimir
- Bencedi Gyula
- Beole Stefania
- Berceanu Ionela
- Bercuci Alexandru
- Berdnikov Yaroslav
- Berenyi Daniel
- Bertens Redmer Alexander
- Berzano Dario
- Betev Latchezar
- Bhasin Anju
- Bhat Inayat Rasool
- Bhati Ashok Kumar
- Bhattacharjee Buddhadeb
- Bhom Jihyun
- Bianchi Livio
- Bianchi Nicola
- Bianchin Chiara
- Bielcik Jaroslav
- Bielcikova Jana
- Bilandzic Ante
- Biswas Rathijit
- Biswas Saikat
- Bjelogrlic Sandro
- Blair Justin Thomas
- Blau Dmitry
- Blume Christoph
- Bock Friederike
- Boettger Stefan
- Bogdanov Alexey
- Boggild Hans
- Boldizsar Laszlo
- Bombara Marek
- Book Julian Heinz
- Borel Herve
- Borissov Alexander
- Borri Marcello
- Bossu Francesco
- Botta Elena
- Bourjau Christian
- Braun-Munzinger Peter
- Bregant Marco
- Breitner Timo Gunther
- Broker Theo Alexander
- Browning Tyler Allen
- Broz Michal
- Brucken Erik Jens
- Bruna Elena
- Bruno Giuseppe Eugenio
- Budnikov Dmitry
- Buesching Henner
- Bufalino Stefania
- Buncic Predrag
- Busch Oliver
- Buthelezi Edith Zinhle
- Buxton Jesse Thomas
- Cabanillas Noris Juan Carlos
- Caffarri Davide
- Cai Xu
- Caines Helen Louise
- Calero Diaz Liliet
- Caliva Alberto
- Calvo Villar Ernesto
- Camerini Paolo
- Carena Francesco
- Carena Wisla
- Carnesecchi Francesca
- Castillo Castellanos Javier Ernesto
- Castro Andrew John
- Casula Ester Anna Rita
- Ceballos Sanchez Cesar
- Cepila Jan
- Cerello Piergiorgio
- Cerkala Jakub
- Chang Beomsu
- Chapeland Sylvain
- Chartier Marielle
- Charvet Jean-Luc Fernand
- Chattopadhyay Subhasis
- Chattopadhyay Sukalyan
- Chelnokov Volodymyr
- Cherney Michael Gerard
- Cheshkov Cvetan Valeriev
- Cheynis Brigitte
- Chibante Barroso Vasco Miguel
- Cho Soyeon
- Chochula Peter
- Choi Kyungeon
- Chojnacki Marek
- Choudhury Subikash
- Christakoglou Panagiotis
- Christensen Christian Holm
- Christiansen Peter
- Chujo Tatsuya
- Chung Suh-Urk
- Chunhui Zhang
- Cicalo Corrado
- Cifarelli Luisa
- Cindolo Federico
- Cleymans Jean Willy Andre
- Colamaria Fabio Filippo
- Colella Domenico
- Collu Alberto
- Colocci Manuel
- Conesa Balbastre Gustavo
- Conesa Del Valle Zaida
- Connors Megan Elizabeth
- Contreras Nuno Jesus Guillermo
- Cormier Thomas Michael
- Corrales Morales Yasser
- Correia Zanoli Henrique Jose
- Cortes Maldonado Ismael
- Cortese Pietro
- Cosentino Mauro Rogerio
- Costa Filippo
- Crochet Philippe
- Cruz Albino Rigoberto
- Cuautle Flores Eleazar
- Cunqueiro Mendez Leticia
- Dahms Torsten
- Dainese Andrea
- Danu Andrea
- Das Debasish
- Das Indranil
- Das Supriya
- Dash Ajay Kumar
- Dash Sadhana
- De Caro Annalisa
- De Cataldo Giacinto
- De Conti Camila
- De Cuveland Jan
- De Falco Alessandro
- De Gruttola Daniele
- De Marco Nora
- De Pasquale Salvatore
- De Sudipan
- Deisting Alexander
- Deloff Andrzej
- Denes Ervin Sandor
- Deplano Caterina
- Dhankher Preeti
- Di Bari Domenico
- Di Mauro Antonio
- Di Nezza Pasquale
- Diaz Corchero Miguel Angel
- Dietel Thomas
- Dillenseger Pascal
- Diozcora Vargas Trevino Aurora
- Divia Roberto
- Djuvsland Oeystein
- Dobrigkeit Chinellato David
- Dobrin Alexandru Florin
- Domenicis Gimenez Diogenes
- Donigus Benjamin
- Dordic Olja
- Drozhzhova Tatiana
- Dubey Anand Kumar
- Dubla Andrea
- Ducroux Laurent
- Dupieux Pascal
- Ehlers Iii Raymond James
- Elia Domenico
- Engel Heiko
- Epple Eliane
- Erazmus Barbara Ewa
- Erdemir Irem
- Erhardt Filip
- Espagnon Bruno
- Estienne Magali Danielle
- Esumi Shinichi
- Eum Jongsik
- Evans David
- Evdokimov Sergey
- Eyyubova Gyulnara
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- Fabris Daniela
- Faivre Julien
- Fantoni Alessandra
- Fasel Markus
- Feldkamp Linus
- Feliciello Alessandro
- Feofilov Grigorii
- Ferencei Jozef
- Fernandez Tellez Arturo
- Ferreira Natal Da Luz Pedro Hugo
- Ferretti Alessandro
- Festanti Andrea
- Feuillard Victor Jose Gaston
- Figiel Jan
- Filchagin Sergey
- Finogeev Dmitry
- Fionda Fiorella
- Fiore Enrichetta Maria
- Fleck Martin Gabriel
- Floris Michele
- Foertsch Siegfried Valentin
- Foka Panagiota
- Fokin Sergey
- Fragiacomo Enrico
- Francescon Andrea
- Frankenfeld Ulrich Michael
- Fuchs Ulrich
- Furget Christophe
- Furs Artur
- Fusco Girard Mario
- Gaardhoeje Jens Joergen
- Gagliardi Martino
- Gago Medina Alberto Martin
- Gallio Mauro
- Gameiro Munhoz Marcelo
- Gangadharan Dhevan Raja
- Ganoti Paraskevi
- Gao Chaosong
- Garabatos Cuadrado Jose
- Garcia-Solis Edmundo Javier
- Gargiulo Corrado
- Gasik Piotr Jan
- Gauger Erin Frances
- Germain Marie
- Gheata Andrei George
- Gheata Mihaela
- Ghosh Premomoy
- Ghosh Sanjay Kumar
- Gianotti Paola
- Giubellino Paolo
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- Gomez Ramirez Andres
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- Gotovac Sven
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- Grachov Oleg Anatolievich
- Graczykowski Lukasz Kamil
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- Grigoras Alina Gabriela
- Grigoras Costin
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- Grigoryev Vladislav
- Grion Nevio
- Gronefeld Julius Maximilian
- Grosse-Oetringhaus Jan Fiete
- Grossiord Jean-Yves
- Grosso Raffaele
- Grynyov Borys
- Guber Fedor
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- Guerzoni Barbara
- Gulbrandsen Kristjan Herlache
- Gunji Taku
- Gupta Anik
- Gupta Ramni
- Haake Rudiger
- Haaland Oystein Senneset
- Hadjidakis Cynthia Marie
- Haiduc Maria
- Hamagaki Hideki
- Hamar Gergoe
- Harris John William
- Harton Austin Vincent
- Hatzifotiadou Despina
- Hayashi Shinichi
- Heckel Stefan Thomas
- Heide Markus Ansgar
- Helstrup Haavard
- Herghelegiu Andrei Ionut
- Herrera Corral Gerardo Antonio
- Hess Benjamin Andreas
- Hetland Kristin Fanebust
- Hillemanns Hartmut
- Hippolyte Boris
- Hosokawa Ritsuya
- Hristov Peter Zahariev
- Huang Meidana
- Humanic Thomas
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- Ippolitov Mikhail
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- Jadhav Manoj Bhanudas
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- Jadlovsky Jan
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- Jakubowska Monika Joanna
- Jang Haeng Jin
- Janik Malgorzata Anna
- Jena Chitrasen
- Jena Satyajit
- Jimenez Bustamante Raul Tonatiuh
- Jones Peter Graham
- Jung Hyungtaik
- Jusko Anton
- Kalinak Peter
- Kalweit Alexander Philipp
- Kamin Jason Adrian
- Kang Ju Hwan
- Kaplin Vladimir
- Kar Somnath
- Karasu Uysal Ayben
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- Keidel Ralf
- Keijdener Darius Laurens
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- Khan Shuaib Ahmad
- Khanzadeev Alexei
- Kharlov Yury
- Kileng Bjarte
- Kim Daehyeok
- Kim Do Won
- Kim Dong Jo
- Kim Hyeonjoong
- Kim Jinsook
- Kim Mimae
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- Kim Se Yong
- Kim Taesoo
- Kirsch Stefan
- Kisel Ivan
- Kiselev Sergey
- Kisiel Adam Ryszard
- Kiss Gabor
- Klay Jennifer Lynn
- Klein Carsten
- Klein Jochen
- Klein-Boesing Christian
- Klewin Sebastian
- Kluge Alexander
- Knichel Michael Linus
- Knospe Anders Garritt
- Kobayashi Taiyo
- Kobdaj Chinorat
- Kofarago Monika
- Kollegger Thorsten
- Kolozhvari Anatoly
- Kondratev Valerii
- Kondratyeva Natalia
- Kondratyuk Evgeny
- Konevskikh Artem
- Kopcik Michal
- Kour Mandeep
- Kouzinopoulos Charalampos
- Kovalenko Oleksandr
- Kovalenko Vladimir
- Kowalski Marek
- Koyithatta Meethaleveedu Greeshma
- Kralik Ivan
- Kravcakova Adela
- Kretz Matthias
- Krivda Marian
- Krizek Filip
- Kryshen Evgeny
- Krzewicki Mikolaj
- Kubera Andrew Michael
- Kucera Vit
- Kuhn Christian Claude
- Kuijer Paulus Gerardus
- Kumar Ajay
- Kumar Jitendra
- Kumar Shyam
- Kurashvili Podist
- Kurepin Alexander
- Kurepin Alexey
- Kuryakin Alexey
- Kweon Min Jung
- Kwon Youngil
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- Ljunggren Hans Martin
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- Loginov Vitaly
- Loizides Constantinos
- Lokesh Kumar
- Lonne Per-Ivar
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- Lopez Xavier Bernard
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- Lunardon Marcello
- Luparello Grazia
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- Mahajan Sanjay
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- Majka Richard Daniel
- Mal'Kevich Dmitry
- Malaev Mikhail
- Maldonado Cervantes Ivonne Alicia
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- Malzacher Peter
- Mamonov Alexander
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- Manzari Vito
- Marchisone Massimiliano
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- Martinez-Garcia Gines
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- Masciocchi Silvia
- Masera Massimo
- Masoni Alberto
- Massacrier Laure Marie
- Mastroserio Annalisa
- Matyja Adam Tomasz
- Mayer Christoph
- Mazer Joel Anthony
- Mazzoni Alessandra Maria
- Mcdonald Daniel
- Meddi Franco
- Melikyan Yuri
- Menchaca-Rocha Arturo Alejandro
- Meninno Elisa
- Mercado-Perez Jorge
- Meres Michal
- Miake Yasuo
- Mieskolainen Matti Mikael
- Mikhaylov Konstantin
- Milano Leonardo
- Millan Almaraz Jesus Roberto
- Milosevic Jovan
- Minervini Lazzaro Manlio
- Mischke Andre
- Mishra Aditya Nath
- Miskowiec Dariusz Czeslaw
- Mitra Jubin
- Mitu Ciprian Mihai
- Mohammadi Naghmeh
- Mohanty Bedangadas
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- Montano Zetina Luis Manuel
- Montes Prado Esther
- Moreira De Godoy Denise Aparecida
- Moretto Sandra
- Morreale Astrid
- Morsch Andreas
- Muccifora Valeria
- Mudnic Eugen
- Muhlheim Daniel Michael
- Muhuri Sanjib
- Mukherjee Maitreyee
- Mulligan James Declan
- Munzer Robert Helmut
- Murray Sean
- Musa Luciano
- Musinsky Jan
- Naik Bharati
- Nair Rahul
- Nandi Basanta Kumar
- Nania Rosario
- Nappi Eugenio
- Naru Muhammad Umair
- Nattrass Christine
- Nayak Kishora
- Nayak Tapan Kumar
- Nazarenko Sergey
- Nedosekin Alexander
- Nellen Lukas
- Ng Fabian
- Nicassio Maria
- Niculescu Mihai
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- Nielsen Borge Svane
- Nikolaev Sergey
- Nikulin Sergey
- Nikulin Vladimir
- Noferini Francesco
- Nomokonov Petr
- Nooren Gerardus
- Norman Jaime
- Nyanin Alexander
- Nystrand Joakim Ingemar
- Oeschler Helmut Oskar
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- Oh Sun Kun
- Ohlson Alice Elisabeth
- Okatan Ali
- Okubo Tsubasa
- Olah Laszlo
- Oleniacz Janusz
- Oliveira Da Silva Antonio Carlos
- Oliver Michael Henry
- Onderwaater Jacobus
- Oppedisano Chiara
- Orava Risto
- Ortiz Velasquez Antonio
- Oskarsson Anders Nils Erik
- Otwinowski Jacek Tomasz
- Oyama Ken
- Ozdemir Mahmut
- Pachmayer Yvonne Chiara
- Pagano Paola
- Pahula Hewage Sandun
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- Pal Susanta Kumar
- Pan Jinjin
- Pandey Ashutosh Kumar
- Papcun Peter
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- Passfeld Annika
- Paticchio Vincenzo
- Patra Rajendra Nath
- Paul Biswarup
- Peitzmann Thomas
- Pereira Da Costa Hugo Denis Antonio
- Pereira De Oliveira Filho Elienos
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- Perez Lara Carlos Eugenio
- Perez Lezama Edgar
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- Peskov Vladimir
- Pestov Yury
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- Ploskon Mateusz Andrzej
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- Pochybova Sona
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- Poljak Nikola
- Poonsawat Wanchaloem
- Pop Amalia
- Porteboeuf Sarah Julie
- Porter R Jefferson
- Pospisil Jan
- Prasad Sidharth Kumar
- Preghenella Roberto
- Prino Francesco
- Pruneau Claude Andre
- Pshenichnov Igor
- Puccio Maximiliano
- Puddu Giovanna
- Pujahari Prabhat Ranjan
- Punin Valery
- Putschke Jorn Henning
- Qvigstad Henrik
- Rachevski Alexandre
- Raha Sibaji
- Rajput Sonia
- Rak Jan
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- Rasanen Sami Sakari
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- Read Kenneth Francis
- Redlich Krzysztof
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- Sefcik Michal
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- Sekiguchi Yuko
- Sekihata Daiki
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- Shigaki Kenta
- Shtejer Diaz Katherin
- Sibiryak Yury
- Siddhanta Sabyasachi
- Sielewicz Krzysztof Marek
- Siemiarczuk Teodor
- Silvermyr David Olle Rickard
- Silvestre Catherine Micaela
- Simatovic Goran
- Simonetti Giuseppe
- Singaraju Rama Narayana
- Singh Ranbir
- Singha Subhash
- Singhal Vikas
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- Sitar Branislav
- Sitta Mario
- Skaali Bernhard
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- Smirnov Nikolai
- Snellings Raimond
- Snellman Tomas Wilhelm
- Soegaard Carsten
- Song Jihye
- Song Myunggeun
- Song Zixuan
- Soramel Francesca
- Sorensen Soren Pontoppidan
- Sozzi Federica
- Spacek Michal
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- Spyropoulou-Stassinaki Martha
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- Suljic Miljenko
- Sultanov Rishat
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- Thomas Deepa
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- Toia Alberica
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- Vande Vyvre Pierre
- Varga Dezso
- Vargyas Marton
- Varma Raghava
- Vasileiou Maria
- Vasiliev Andrey
- Vauthier Astrid
- Vechernin Vladimir
- Veen Annelies Marianne
- Veldhoen Misha
- Velure Arild
- Venaruzzo Massimo
- Vercellin Ermanno
- Vergara Limon Sergio
- Vernet Renaud
- Verweij Marta
- Vickovic Linda
- Viesti Giuseppe
- Viinikainen Jussi Samuli
- Vilakazi Zabulon
- Villalobos Baillie Orlando
- Villatoro Tello Abraham
- Vinogradov Alexander
- Vinogradov Leonid
- Vinogradov Yury
- Virgili Tiziano
- Vislavicius Vytautas
- Viyogi Yogendra
- Vodopyanov Alexander
- Volkl Martin Andreas
- Voloshin Kirill
- Voloshin Sergey
- Volpe Giacomo
- Von Haller Barthelemy
- Vorobyev Ivan
- Vranic Danilo
- Vrlakova Janka
- Vulpescu Bogdan
- Vyushin Alexey
- Wagner Boris
- Wagner Jan
- Wang Hongkai
- Wang Mengliang
- Watanabe Daisuke
- Watanabe Yosuke
- Weber Michael
- Weber Steffen Georg
- Weiser Dennis Franz
- Wessels Johannes Peter
- Westerhoff Uwe
- Whitehead Andile Mothegi
- Wiechula Jens
- Wikne Jon
- Wilde Martin Rudolf
- Wilk Grzegorz Andrzej
- Wilkinson Jeremy John
- Williams Crispin
- Windelband Bernd Stefan
- Winn Michael Andreas
- Yaldo Chris G
- Yang Hongyan
- Yang Ping
- Yano Satoshi
- Yasar Cigdem
- Yin Zhongbao
- Yokoyama Hiroki
- Yoo In-Kwon
- Yoon Jin Hee
- Yurchenko Volodymyr
- Yushmanov Igor
- Zaborowska Anna
- Zaccolo Valentina
- Zaman Ali
- Zampolli Chiara
- Zaporozhets Sergey
- Zardoshti Nima
- Zarochentsev Andrey
- Zavada Petr
- Zavyalov Nikolay
- Zbroszczyk Hanna Paulina
- Zgura Sorin Ion
- Zhalov Mikhail
- Zhang Haitao
- Zhang Xiaoming
- Zhang Yonghong
- Zhang Zuman
- Zhao Chengxin
- Zhigareva Natalia
- Zhou Daicui
- Zhou You
- Zhou Zhuo
- Zhu Hongsheng
- Zhu Jianhui
- Zichichi Antonino
- Zimmermann Alice
- Zimmermann Markus Bernhard
- Zinovjev Gennady
- Zyzak Maksym
- Publication venue
- Publication date
- 14/09/2015
- Field of study
We present measurements of the azimuthal dependence of charged jet production in central and semi-central root s(NN) = 2.76 TeV Pb-Pb collisions with respect to the second harmonic event plane, quantified as nu(ch)(2) (jet). Jet finding is performed employing the anti-k(T) algorithm with a resolution parameter R = 0.2 using charged tracks from the ALICE tracking system. The contribution of the azimuthal anisotropy of the underlying event is taken into account event-by-event. The remaining (statistical) region-to-region fluctuations are removed on an ensemble basis by unfolding the jet spectra for different event plane orientations independently. Significant non-zero nu(ch)(2) (jet) is observed in semi-central collisions (30-50% centrality) for 20 <p(T)(ch) (jet) <90 GeV/c. The azimuthal dependence of the charged jet production is similar to the dependence observed for jets comprising both charged and neutral fragments, and compatible with measurements of the nu(2) of single charged particles at high p(T). Good agreement between the data and predictions from JEWEL, an event generator simulating parton shower evolution in the presence of a dense QCD medium, is found in semi-central collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
- Author
- Abbas Jalal
- Abraham Sybil
- Ackert Jessica
- Adams Patricia
- Aggarwala Gaurav
- Aher Nutan
- Ahlqvist Jørn
- Ahn Chul Woo
- Akers Teresa
- Akhras Ronald
- Akhter Faiq
- Aksentyev Sergey
- Al Kawas Firas
- Alexander Karen
- Althouse Denise
- Altobelli Desma
- Alvarisqueta Andres
- Ambrosy Andrew
- Andersen James
- Andersen Ulla
- Anderson Michelle
- Anglade Moise
- Arbañil Hugo
- Arciszewska Malgorzata
- Argoud Georges
- Ariani Mehrdad
- Ashdji Reswan
- Avogaro Angelo
- Avramidis Iakovos
- Axthelm Christoph
- Aye Myint
- Babi Charleen
- Bachus Erasmus
- Baik Sei-Hyun
- Bailey Matt
- Bakhtari Ladan
- Baksi Arun
- Balasubramani Mathangi
- Baldovino Jorge
- Banach Marek
- Banerjee Subhash
- Bartlett Andrew
- Bartone Susan
- Baum Howard
- Bays Harold
- Bazhan Larysa
- Beasley Richard
- Beaudry Yves
- Beaulieu Gail
- Beboso Ronnie
- Bedard Jacques
- Beijerbacht Hugo Peter
- Belfort de Aguiar Renata
- Benjamin Sabrina
- Berger Dirk
- Berlingieri Joseph
- Berndtsson Blom Katarina
- Besada Diego
- Bethel M Angelyn
- Bhagwat Ravi
- Bhargava Anuj
- Bhosale Archana
- Bieler Tasso
- Bijata-Bronisz Renata
- Birkeland Kare
- Birkenfeld Andreas
- Blagden Mark
- Bloomfield Gerald
- Bode Bruce
- Boemi Massimo
- Bonadonna Riccardo
- Bondar Irina
- Bott Jochen
- Bousboulas Stavros
- Boye Alain
- Bratcher Christina
- Breneman Jody
- Briskin Toby
- Bristianou Magdalini
- Brockmyre Andrew
- Broughton Raymond
- Brown Judith
- Brown Kim
- Brychta Tomas
- Brønnum-Schou Jens
- Budhraja Madhusudan
- Bull Georgina
- Bundy Charles
- Burgess Lesley
- Busch Klaus
- Caca Karel
- Cadinot Didier
- Calderon Jorge
- Calella Pedro
- Califf Robert M
- Calvo Gómez Carlos
- Camacho Luis
- Cannon Kevin
- Cano Rodríguez Isidoro
- Cantero Maria Cecilia
- Carr Jewell
- Casson Ed
- Castaño Patricia
- Castro Conde Almudena
- Cathcart Harold
- Cavale Arvind
- Cech Vladimir
- Cequier Fillat Angel
- Cervantes-Escárcega Jose-Luis
- Cha Bong-Soo
- Chau Tuan
- Chaykin Louis
- Chehayeb Raja
- Chen David
- Chen Jung-Fu
- Chertkoff Alejandro
- Cheung Deanna
- Cheung Stephen
- Chevts Julia
- Chiang Chern-En
- Childress Richard
- Christian Tamra
- Chung Choon-Hee
- Coetzee Kathleen
- Cohen Allan
- Coker Rebecca
- Cole Joanna
- Collier Jeannie
- Condit Jonathan
- Consoli Agostino
- Conway James
- Cooksey Erin
- Cookson Tobias
- Cooper John
- Cooper Lauren
- Copland Allan
- Cornel Jan
- Cornett George Mitchell
- Crenier Laurent
- Cuadrado Jesus
- Cuatrecasas Cambra Guillem
- Cusson Jean
- D'Agostino Ralph B
- D'Agostino Ralph B.
- Daga Shruti
- Damyanova Velichka
- Dauber Ira
- Davila William
- Dawood Saleem
- De Armas Luis
- De Cosmo Salvatore
- De Loredo Luis
- De Teresa Parreño Luis
- de Álvaro Moreno Fernando
- Dean Julius
- Debroye Corinne
- Del Prato Stefano
- Del Prato Stefano
- Delgado Lista Javier
- Della Siega Anthony
- DeMets David
- Demidova Irina
- Derezinski Tadeusz
- Deshpande Sameer
- Detweiler Robert
- Devore Adam
- Di Bartolo Paolo
- Di Giovanna Michael
- Diaz Ernesto
- Dimitriadis Georgios
- Dimitrov Stefan
- Distiller Larry
- Dombrowski Keith
- Dominguez Andrea
- Domínguez Escribano José Ramón
- Donaldson Jill
- Donaubauer Torsten
- Dor Isaac
- Dotta Francesco
- Dreval Alexander
- Drummond Waymon
- Dumas Richard
- Dumbre Snehal
- Dungan Kathleen
- Durán García Santiago
- Duyck Francis
- Dvorakova Eva
- Dzongowski Peter
- Eagerton Donald
- Eapen Zubin
- Earl John
- Eaton Charles
- Ebo Geraldine
- Edelsberger Tomas
- Eliasson Bjorn
- Eliasson Ken
- Elisaf Moses
- Ellison Howard
- Elvira González Javier
- Emslie-Smith Alistair
- Endsley Patricia
- Enns Robert
- Erlinger Rudolf
- Ershova Olga
- Español Maria Vanesa
- Espinoza Augusto Dextre
- Farris Neil
- Ferguson Murdo
- Fernandez-Salazar Eva
- Fernández Rodríguez José María
- Fiel Thomas
- Finkelstein Hernan
- Firek Anthony
- First Brian
- Fleming John
- Flota-Cervera Luis Fernando
- Forgosh Les
- Frechtel Gustavo
- French William
- Fretes Jose
- Friedman Daniel
- Frontoni Simona
- Funke Klaus
- Fushtey Ivan
- Gadzinski Waldemar
- Gajek Jacek
- Galatius Søren
- Galetta Marianna
- Galstyan Gagik
- Gambineri Alessandra
- Gandy Winston
- Garcia Ronald
- Garganeeva Alla
- Garrido Santos Natalia
- Garrido Elizabeth
- Garvey Louisa
- Gaudet Daniel
- Gazzaruso Carmine
- Gentry Tracy
- Giaccari Andrea
- Gill Santosh
- Giorgino Francesco
- Goday Arno Alberto
- Godse Rupali
- Gomez Huelgas Ricardo
- Gonzales Rolando Vargas
- Gonzalez Joaquin
- González Juanatey José Ramón
- González-González José Gerardo
- Goodman Shaun
- Gordon Murray
- Gouet Didier
- Grachova Mariya
- Granger Christopher B
- Granger Christopher B.
- Green Fiona
- Green Jennifer B
- Green Jennifer B
- Greene Deb
- Greene Stephen
- Grondin Francois
- Grosskopf Josef
- Groutars Reginald G.E.J.
- Guerci Bruno
- Guice Michael
- Guimaraes Patricia
- Gulseth Hanne
- Gummadi Siva
- Gunstone Anthony
- Gupta Anil
- Gupta Milan
- Gupta Nikita
- Guttormsen Gaute
- Ha JuYoung
- Hackenyos Jonathan
- Haddock Trevorlyn
- Hagenow Andreas
- Hairston Kristen
- Hajdú Csaba
- Halciakova Katarina
- Halperin Frank
- Haluzik Martin
- Hamann Monika
- Hanson Lenita
- Haque Ghazala
- Harcsa Eleonóra
- Harris Tara
- Harrison Lindsay
- Harrison Rob
- Hartard Manfred
- Hartman Israel
- Heitner John
- Hejeebu Srini
- Henry Patrick
- Hereghty Belinda
- Hermany Paul
- Hernandez Mijares Antonio
- Hernandez Adrian F
- Hernandez Adrian F.
- Hernandez-Cassis Carlos
- Heymer Peter
- Hidalgo Horacio
- Higgins Alexander
- Hoek Boudewijn A
- Holman Rury
- Hoogslag Pieter A.M.
- Houle Pierre-Alain
- Hove Jens
- Howell Christina
- Hramiak Irene
- Huppertz Wolfgang
- Hutayanon Pisit
- Ibrahim Hassan
- Illies Gabriele
- Issa Basil
- Izmozherova Nadezhda
- Jackson-Voyzey Ewart
- Jacob Stephan
- Jacobs Shahram
- James Kourtnei
- James Rachel
- Jang Hak Chul
- Janmohamed Salim
- Janmohamed Salim
- Jarosz Marie
- Jenkins Wendy
- Jensen Jan Skov
- Jerjes-Díaz Carlos Sánchez
- Jiménez Díaz Víctor Alfonso
- Jintapakorn Woravut
- Jodar Gimeno Esteban
- Johnson Andrew
- Johnson David
- Johnson Megan
- Jones Michael
- Jones Nigel P
- Jones Nigel P
- Jordan Dedrick
- Joshi Parag
- Jung Thomas
- Kadgaonkar Neha
- Kahrmann Gerd
- Karetnikova Victoria
- Karka Mounika
- Karmalkar Anisha
- Kast Petra
- Kaster Steven
- Katerenchuk Vitaliy
- Kellerer Monika
- Kellum Daniel
- Kelly Aoife
- Kempe Hans-Peter
- Kessler Laurence
- Khandelwal Chaitali
- Kharakhulakh Marina
- Khariouzov Andrei
- Khokhlov Aleksandr
- Kim Chong-Jin
- Kim Christopher
- Kim Ellen
- Kim Hye Soon
- Kim In Joo
- Kirby William
- Klausmann Gerhard
- Klein Christiane
- Kleinecke-Pohl Uwe
- Kleinertz Klaus
- Klodawska Katarzyna
- Knouse Albert
- Kobalava Zhanna
- Kober Lars
- Koch Thorsten
- Kocsis Gyozo
- Kolls Brad
- Kong David
- Konyves Laszlo
- Kooy Adriaan
- Korpachev Vadym
- Kosch Christine
- Koshelskaya Olga
- Kosiborod Mikhail
- Koskinen Pekka
- Kosmacheva Elena
- Kostin Vladimir
- Kotsa Kalliopi
- Kouz Simon
- Kovacheva Snezhina
- Kovacs Christopher
- Koziolova Natalia
- Kragten Johannes A.
- Kravchun Nonna
- Kristiansen Ole Peter
- Krizova Jarmila
- Krzyzagorska Ewa
- Kulback Steven
- Kulkarni Mangesh
- Kumar Mariananda
- Kumar Rakesh
- Kumar Somesh
- Kumari Aditi
- Kuruvanka Tulsidas
- Kuzin Anatoly
- Labroo Ajay
- Lalau Jean-Daniel
- Landry Daniel
- Larin Oleksandr
- Larnefeldt Hans
- Lasswell William
- Lastuvka Jiri
- Lauder Steven
- Lauro Davide
- Lee Eun Young
- Lee Hyoung Woo
- Lee Kwan-Woo
- Lee Moon Kyu
- Leiter Lawrence A
- Leiter Lawrence A.
- Lentz John
- Lenzmeier Thomas
- Lesnov Victor
- Lewis David
- Li Wenyan
- Li Zhaoping
- Lieverse Aloysius G.
- Lif-Tiberg Cornelia
- Lillestol Michael
- Linderfalk Carina
- Lindsay Alistair
- Little Raymond
- Litvak Marcos
- Llamas Edmundo-Alfredo Bayram
- Lokhngina Yuliya
- Lombard Landman
- Longley Troy
- Lonn Eva
- Lopes Renato
- Lopez-Sendon Jose
- Lorimer Jamie
- Lorra Babette
- Lorraine Richard
- Loureyro Juan
- Lozanov Lachezar
- Lucas Morante Tomás
- Luedemann Joerg
- Luna Alejandro
- Lund Gustav
- Lund Per
- Lundman Pia
- Luttermann Matthias
- Lysenko Tatyana
- Maclean Malcolm
- Madej Andrzej
- Maffei Laura
- Makotoko Ellen
- Maldonado Natacha
- Mandal Trisha
- Mandawat Aditya
- Mankovsky Boris
- Manrique Helard
- Marazuela Monica
- Margaritov Viktor
- Markov Valentin
- Marquess Marsha
- Martell Claros Nieves
- Mathews Robin
- Mathieu Chantal
- Mauricio Puente Didac
- Maxeiner Stephan
- Mayorov Alexander
- McGuire Darren
- McKeown-Biagas Cecilia
- McKnight John
- McLaughlin Patricia
- McMurray John J.V.
- McMurray John J.V.
- McNeill Robert
- Mehta Anand
- Mehta Rajendra
- Melchior Thomas
- Melidonis Andreas
- Melloni Chiara
- Mena Ribas Elena
- Merino Torres Juan Francisco
- Mezquita Raya Pedro
- Mhambrey Ankita
- Miekus Pawel
- Migdalis Ilias
- Mihaylova-Shumkova Rositsa
- Milek Karsten
- Miller Alan
- Miller Diane
- Mitrakou Asimina
- Moelle Andrea
- Mohr Gasparini Diego
- Moiseev Sergey
- Moodley Rajendran
- Moon Keon-Woong
- Morales-Palomares Ellen
- Moran Joseph
- Morawski Emily
- Moris Linda
- Mucsi János
- Murphy Karen
- Muzulu Solomon
- Muñoz Ernesto German Cardona
- Myasoedova Svetlana
- Mykhalchyshyn Galyna
- Myshanych Halyna
- Nadar Madhumitha
- Nadar Venkatesh
- Naicker Pallavi
- Namgung June
- Nauck Michael
- Neumann Gerhard
- Nikolaeva Antoaneta
- Nischik Ruth
- Noronha Drusilla
- Nubiola Calonge Andreu
- Nyvad Ole
- O'Connell Ian
- O'Connor Thomas
- O'Mahony William
- Odio Alberto
- Oehrig-Pohl Edith
- Oleksyk Olga
- Olesinska-Mader Martyna
- Olsson Åke
- Oosthuysen Wessels
- Opiela Jaroslaw
- Ordoñez Sánchez Xavier
- Orio Silvia
- Orlenko Valeriia
- Orsi Emanuela
- Overton Robert
- Oyesile Babatunde
- Ozaki Risa
- Pagkalos Emmanouil
- Paolisso Giuseppe
- Papanas Nikolaos
- Pappas Angelos
- Park Kyong Soo
- Parker Reginald
- Pascoe-Gonzalez Sara
- Pascual Izuel Jose Maria
- Pashkovska Nataliia
- Patel Chetan
- Patel Prashant
- Patel Rajesh
- Patel Rajivkumar
- Patel Vickas
- Patil Ashwini P
- Patil Suradnya
- Patterson Catherine
- Pauker Zsolt
- Pearson Ewan
- Pelayo-Orozco Emilia Susana
- Perea Castilla Verónica
- Perez Manghi Federico
- Perez Soto Isabel
- Perez Kathleen
- Perriello Gabriele
- Pertseva Nataliia
- Pesarchick Jean
- Peterson Sean
- Petit Catherine
- Petrosyan Olena
- Petró Gizella
- Petunina Nina
- Philip Sam
- Phillips Lawrence
- Phrommintikul Arintaya
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- Pinto Miguel
- Piperek Martin
- Plassmann Georg
- Plés Zsolt
- Pohlmeier Lars
- Pontiroli Antonio
- Ponzani Paola
- Pope Connie
- Potnis Omkar
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- Prakash Rahul
- Price Lauren
- Price-Olsen Emma
- Proepper Felix
- Prymkova Vera
- Pérez Pérez Antonio
- Quesada Charneco Miguel
- Quesada Simón Angustias
- Raad George
- Raclavska Lea
- Rahman Aref
- Raikhel Marina
- Raisinghani Ajit
- Rajan Raj
- Ramirez-Diaz Santiago-Paulino
- Raorane Amruta
- Rasouli Neda
- Rauzi Frank
- Rebrov Andrey
- Redón Mas Josep
- Regner Stefan
- Rego Iraeta Antonia
- Reich Dennis
- Rethaford Renee
- Revesz Katalin
- Revoredo Frederick Massucco
- Rich Jenny
- Richards Jackie
- Riddle Matthew
- Rieker Werner
- Rincon Luis Zapata
- Rivellese Angela Albarosa
- Rodriguez Alvarez Maria
- Rodriguez Papini Nelson
- Rodríguez Rodríguez Irene
- Roe Matthew
- Rohr Kathryn
- Romanczuk Piotr
- Rose Ludger
- Roseman Hal
- Rosenberg Anne
- Rosenberg Anne E
- Rosenbloom Alan
- Ross Jorge
- Roush Jennifer
- Rovner Sergio
- Russell Rachael
- Ruyatkina Ludmila
- Saba Fadi
- Sabol Mary Beth
- Sabán Ruiz José
- Sachson Richard
- Sahu Shruti
- Sala Jorgelina
- Saldana-Mendoza Arturo
- Salmonsson Staffan
- Samer Holger
- Samoylova Julia
- Sampanis Christos
- Sandhu Chamandeep
- Sanmartin Berglund Johan
- Sansanayudh Nakarin
- Sarvan Mohamed
- Saswadkar Aarti
- Sauter Joachim
- Sazonova Olga
- Schabauer Alex
- Schaper Frank
- Scheen André
- Schiffer Clemens
- Schleiden Debra
- Schmidt Juergen
- Schneider Ricky
- Scholz Bernd-M.
- Schou Morten
- Schubert Jessica
- Schuchard Timothy
- Schultheis Ron
- Schulze Joerg
- Schuyler Jones William
- Schygiel Pablo
- Sedani Sangeeta
- Segner Alexander
- Sensenbrenner John
- Sesti Giorgio
- Seufert Jochen
- Shaik Fayaz
- Shannon Jennifer
- Sharma Abhinav
- Sharma Richa
- Shavadia Jay
- Shestakova Marina
- Shilkina Natalia
- Shinde Rakesh
- Shitut Aditi
- Shlesinger Yshay
- Siegel Anna
- Sigal Helena
- Sigmon Kristina
- Sigmon Kristina N
- Silhova Elena
- Sinay Isaac
- Singh Narendra
- Sivalingam Kanagaratnam
- Sjöberg Folke
- Skokowska Ewa
- Smirnov Ivan
- Smith Paul
- Smith Peter
- Soffer Joseph
- Sokolova Nadezhda
- Solanki Sheetal
- Somerville Matthew
- Somerville Matthew C
- Soto González Alfonso
- Sowell Margaret
- Sposetti Georgina
- Srimahachota Suphot
- St-Maurice Francois
- Stankiewicz Andrzej
- Stasinska Teresa
- Stead Janet
- Steindorf Joerg
- Stewart Murray
- Stockhausen Juergen
- Stone Allegra
- Stonesifer Larry
- Storey Daniel
- Stoyanova Zhasmina
- Stuebler Petra
- Suh David
- Sukumaran Usha
- Swart Hendrik P.
- Sándor Vangel
- Söderberg Stefan
- Taeschner Heidrun
- Taft Lin
- Tahir Mohammed
- Tan Anjanette
- Tan Choon Beng Kathryn
- Tan Marilyn
- Taylon Alain
- Tentolouris Nikolaos
- Tews Dietrich
- Thakkar Maitreya
- Thomas Betsy
- Thorpe Karl
- Thorpe Karl M
- Thuan Jean-Francois
- Tien Kai Jen
- Tinahones Madueno Francisco
- Tirador Louie
- Tonolo Giancarlo
- Torres-Colores Jose Juan
- Torstensson Ingemar
- Trescoli Serrano Carlos
- Trevisan Roberto
- Tricoci Pierluigi
- Tripathy Devjit
- Trznadel-Morawska Iwona
- Tsapas Apostolos
- Tschoepe Diethelm
- Tseng Shih-Ting
- Tu Shih-Te
- Tugwell Barna
- Tzatzagou Glykeria
- Ulied Armiñana Angels
- Ulla Maria
- Urbanek Robin
- Uwaifo Gabriel
- Van Gaal Luc
- Vandyne Beth
- Vaphare Ashok
- Vasilevskaya Olga
- Vass Viktor
- Vedere Amarnath
- Vemulapalli Sreekanth
- Venugopal Chandra
- Verbovaya Nelli
- Vercammen Chris
- Verra Fernando
- Vidrio-Velázquez Maricela
- Viergever Eric P.
- Villagordoa-Mesa Juan
- Vishneva Elena
- Vizel Saul
- Vlasenko Maryna
- Vo Anthony
- Voinot Christel
- Vorobyev Sergey
- Vorokhobina Natalya
- Vouillarmet Julien
- Vrkoc Jan
- Wang Chih-Yuan
- Wang Ji-Hung
- Watson Anthony
- Watson David
- Welch Michelle
- Welker James
- White Alexander
- Wilhelm Karl
- Willis John
- Wilson Matt
- Wilson Tim
- Witek Robert
- Wium Cecilie
- Womer Terese
- Woo Vincent
- Wraight Ella
- Wynne Alan
- Xing Weibing
- Yamwong Sukit
- Yazdani Shahram
- Ye June
- Yoo Soon Jib
- Yordanov Victor
- Yu Jaemyung
- Zabalua Silvina
- Zaidman Cesar
- Zang Eddie
- Zanozina Olga
- Zeller-Stefan Helga
- Zhdanova Elena
- Zlova Tetiana
- Zubiate Carlos
- Zykova Tatyana
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background:
Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke.
Methods:
We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged 40 years and older with type 2 diabetes and cardiovascular disease (at a 1:1 ratio) to groups that either received a subcutaneous injection of albiglutide (30–50 mg, based on glycaemic response and tolerability) or of a matched volume of placebo once a week, in addition to their standard care. Investigators used an interactive voice or web response system to obtain treatment assignment, and patients and all study investigators were masked to their treatment allocation. We hypothesised that albiglutide would be non-inferior to placebo for the primary outcome of the first occurrence of cardiovascular death, myocardial infarction, or stroke, which was assessed in the intention-to-treat population. If non-inferiority was confirmed by an upper limit of the 95% CI for a hazard ratio of less than 1·30, closed testing for superiority was prespecified. This study is registered with ClinicalTrials.gov, number NCT02465515.
Findings:
Patients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat population, were evaluated for a median duration of 1·6 years and were assessed for the primary outcome. The primary composite outcome occurred in 338 (7%) of 4731 patients at an incidence rate of 4·6 events per 100 person-years in the albiglutide group and in 428 (9%) of 4732 patients at an incidence rate of 5·9 events per 100 person-years in the placebo group (hazard ratio 0·78, 95% CI 0·68–0·90), which indicated that albiglutide was superior to placebo (p<0·0001 for non-inferiority; p=0·0006 for superiority). The incidence of acute pancreatitis (ten patients in the albiglutide group and seven patients in the placebo group), pancreatic cancer (six patients in the albiglutide group and five patients in the placebo group), medullary thyroid carcinoma (zero patients in both groups), and other serious adverse events did not differ between the two groups. There were three (<1%) deaths in the placebo group that were assessed by investigators, who were masked to study drug assignment, to be treatment-related and two (<1%) deaths in the albiglutide group.
Interpretation:
In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events. Evidence-based glucagon-like peptide 1 receptor agonists should therefore be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes.
Funding:
GlaxoSmithKline
Forward-central two-particle correlations in p-Pb collisions at root s(NN)=5.02 TeV
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aimo Ilaria
- Aiola Salvatore
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- Vinogradov Yury
- Virgili Tiziano
- Vislavicius Vytautas
- Viyogi Yogendra
- Vodopyanov Alexander
- Volkl Martin Andreas
- Voloshin Kirill
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- Von Haller Barthelemy
- Vorobyev Ivan
- Vranic Danilo
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- Vulpescu Bogdan
- Vyushin Alexey
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- Wang Mengliang
- Wang Yifei
- Watanabe Daisuke
- Watanabe Yosuke
- Weber Michael
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- Wessels Johannes Peter
- Westerhoff Uwe
- Wiechula Jens
- Wikne Jon
- Wilde Martin Rudolf
- Wilk Grzegorz Andrzej
- Wilkinson Jeremy John
- Williams Crispin
- Windelband Bernd Stefan
- Winn Michael Andreas
- Yaldo Chris G
- Yang Hongyan
- Yang Ping
- Yano Satoshi
- Yin Zhongbao
- Yokoyama Hiroki
- Yoo In-Kwon
- Yurchenko Volodymyr
- Yushmanov Igor
- Zaborowska Anna
- Zaccolo Valentina
- Zaman Ali
- Zampolli Chiara
- Zaporozhets Sergey
- Zardoshti Nima
- Zarochentsev Andrey
- Zavada Petr
- Zavyalov Nikolay
- Zbroszczyk Hanna Paulina
- Zgura Sorin Ion
- Zhalov Mikhail
- Zhang Chunhui
- Zhang Haitao
- Zhang Xiaoming
- Zhang Yonghong
- Zhao Chengxin
- Zhigareva Natalia
- Zhou Daicui
- Zhou You
- Zhou Zhuo
- Zhu Hongsheng
- Zhu Jianhui
- Zhu Xiangrong
- Zichichi Antonino
- Zimmermann Alice
- Zimmermann Markus Bernhard
- Zinovjev Gennady
- Zyzak Maksym
- Publication venue
- Publication date
- 26/06/2015
- Field of study
Two-particle angular correlations between trigger particles in the forward pseudorapidity range (2.5 2GeV/c. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B. V.Peer reviewe
Event-shape engineering for inclusive spectra and elliptic flow in Pb-Pb collisions at root(NN)-N-S=2.76 TeV
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aimo Ilaria
- Aiola Salvatore
- Ajaz Muhammad
- Akindinov Alexander
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alfaro Molina Jose Ruben
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski Jonas
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Armesto Perez Nestor
- Arnaldi Roberta
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Bach Matthias Jakob
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Baldisseri Alberto
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- Barnby Lee Stuart
- Bartalini Paolo
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- Bartsch Esther
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- Basile Maurizio
- Bastid Nicole
- Basu Sumit
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- Batista Camejo Arianna
- Batyunya Boris
- Batzing Paul Christoph
- Bearden Ian Gardner
- Beck Hans
- Bedda Cristina
- Behera Nirbhay Kumar
- Belikov Iouri
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- Bellwied Rene
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- Publication venue
- Publication date
- 22/07/2015
- Field of study
Peer reviewe
Long-range angular correlations on the near and away side in p–Pb collisions at
- Author
- Abdiel Ramirez Reyes
- Adam Ryszard Kisiel
- Adam Tomasz Matyja
- Adam Wlodzimierz Jacholkowski
- Adam Szczepankiewicz
- Adela Kravcakova
- Aditya Nath Mishra
- Adrian Sevcenco
- Adriana Telesca
- Airton Deppman
- Ajay Kumar Dash
- Alberica Toia
- Alberto Baldisseri
- Alberto Collu
- Alberto Gago
- Alberto Masoni
- Alejandro Szanto de Toledo
- Alessandra Maria Mazzoni
- Alessandra Fantoni
- Alessandro De Falco
- Alessandro Feliciello
- Alessandro Grelli
- Alessandro Pesci
- Alexander Philipp Kalweit
- Alexander Akindinov
- Alexander Borissov
- Alexander Hansen
- Alexander Kluge
- Alexander Mamonov
- Alexander Nedosekin
- Alexander Ochirov
- Alexander Vinogradov
- Alexander Vodopianov
- Alexander Wilk
- Alexandr Tumkin
- Alexandre Alarcon do Passo Suaide
- Alexandre Nyanin
- Alexandre Rachevski
- Alexandre Shabetai
- Alexandru Florin Dobrin
- Alexandru Bercuci
- Alexei Kaidalov
- Alexei Khanzadeev
- Alexei Pavlinov
- Alexey Bogdanov
- Alexey Kuryakin
- Alexey Vyushin
- Alexis Jean Michel Mas
- Alfonso Tarazona Martinez
- Alfredo Musso
- Alice Zimmermann
- Alina Gabriela Grigoras
- Alis Rodriguez Manso
- Alla Maevskaya
- Alphonse Rademakers
- Amalia Pop
- Amaya Ofelia Casanova Diaz
- Ana Maria Marin
- Anais Annick Erica Bergognon
- Anand Kumar Dubey
- Anatoly Kolojvari
- Anders Garritt Knospe
- Anders Nils Erik Oskarsson
- Andras Gabor Agocs
- Andre Augustinus
- Andre Mischke
- Andrea Agostinelli
- Andrea Alici
- Andrea Dainese
- Andrea Danu
- Andrea Dubla
- Andrea Festanti
- Andrea Francescon
- Andrea Rossi
- Andreas Arend
- Andreas Morsch
- Andrei Geae Gheata
- Andrei Ionut Herghelegiu
- Andres Sandoval
- Andrew Marshall Adare
- Andrey Ivanov
- Andrey Kazantsev
- Andrey Reshetin
- Andrey Vasiliev
- Andrey Zarochentsev
- Andry Malala Rakotozafindrabe
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- Andrzej Rybicki
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- Anik Gupta
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- Anselmo Margotti
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- Timothy Symons
- Timur Pocheptsov
- Tinku Sinha
- Tiziano Virgili
- Tobias Krawutschke
- Tomas Robert Aronsson
- Tomasz Jan Pawlak
- Tome Anticic
- Tomi Samuli Raiha
- Tomoya Tsuji
- Torsten Alt
- Toru Sugitate
- Trine Spedstad Tveter
- Tuomo Esa Aukusti Kalliokoski
- Tuva Richert
- Tyler Allen Browning
- Udo Wolfgang Kebschull
- Ulrich Michael Frankenfeld
- Ulrich Fuchs
- Uwe Westerhoff
- Valentina Zaccolo
- Valeria Muccifora
- Valerie Barret
- Valerio Altini
- Valery Kondratiev
- Valery Punin
- Vardanush Papikyan
- Vasco Miguel Chibante Barroso
- Vasile Catanescu
- Vasily Kushpil
- Vedran Nikolic
- Venelin Anguelov
- Vera Loggins
- Vercellin Ermanno
- Veronica Canoa Roman
- Victor Trubnikov
- Vikas Singhal
- Vincenzo Paticchio
- Vitaly Loginov
- Vito Lenti
- Vito Manzari
- Vladimir Ivanov
- Vladimir Kaplin
- Vladimir Kovalenko
- Vladimir Nikulin
- Vladimir Peskov
- Vladimir Pospisil
- Vladimir Samsonov
- Vladimir Vechernin
- Vladimir Wagner
- Vladislav Grigoriev
- Vladislav Manko
- Vojtech Petracek
- Volker Lindenstruth
- Weilin Yu
- Werner Riegler
- Wiktor Stanislaw Peryt
- Wisla Carena
- Wladyslaw Henryk Trzaska
- Woo Jin Park
- Xavier Bernard Lopez
- Xianbao Yuan
- Xiangrong Zhu
- Xianguo Lu
- Xiaoming Zhang
- Xitzel Sanchez Castro
- Yaldo Chris G.
- Yannick Denis Zoccarato
- Yaping Wang
- Yaroslav Berdnikov
- Yasuo Miake
- Yasuto Hori
- Yaxian Mao
- Yevgen Martynov
- Yifei Wang
- Yogendra Viyogi
- Yong Wook Baek
- Yorito Yamaguchi
- You Zhou
- Youngil Kwon
- Yury Kharlov
- Yury Kucheriaev
- Yury Pestov
- Yury Sibiriak
- Yury Vinogradov
- Yves Roland Schutz
- Yvonne Chiara Pachmayer
- Zabulon Vilakazi
- Zaida Conesa del Valle
- Zhongbao Yin
- Zubayer Ahammed
- Zuzana Harmanova
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2013
- Field of study
Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC
- Author
- Acharya Shreyasi
- Adamova Dagmar
- Adolfsson Jonatan
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aiola Salvatore
- Akindinov Alexander
- Al-turany Mohammad
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alfaro Molina Jose Ruben
- Ali Yasir
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altenkamper Lucas
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andreou Dimitra
- Andrews Harry Arthur
- Andronic Anton
- Anguelov Venelin
- Anson Christopher Daniel
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Arnaldi Roberta
- Arnold Oliver Werner
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Baldisseri Alberto
- Ball Markus
- Baral Rama Chandra
- Barbano Anastasia Maria
- Barbera Roberto
- Barile Francesco
- Barioglio Luca
- Barnafoldi Gergely Gabor
- Barnby Lee Stuart
- Bartalini Paolo
- Barth Klaus
- Bartsch Esther
- Bashir Butt Jamila
- Bastid Nicole
- Basu Sumit
- Batigne Guillaume
- Batyunya Boris
- Batzing Paul Christoph
- Bautista Guzman Irais
- Bazo Alba Jose Luis
- Bearden Ian Gardner
- Beck Hans
- Bedda Cristina
- Behera Nirbhay Kumar
- Belikov Iouri
- Bellini Francesca
- Bello Martinez Hector
- Bellwied Rene
- Belyaev Vladimir
- Bencedi Gyula
- Beole Stefania
- Bercuci Alexandru
- Berdnikov Yaroslav
- Berenyi Daniel
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- Zarochentsev Andrey
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- Zbroszczyk Hanna Paulina
- Zhalov Mikhail
- Zhang Haitao
- Zhang Xiaoming
- Zhang Yonghong
- Zhang Zuman
- Zhao Chengxin
- Zhigareva Natalia
- Zhou Daicui
- Zhou You
- Zhou Zhuo
- Zhu Hongsheng
- Zhu Jianhui
- Zhu Ya
- Zichichi Antonino
- Zimmermann Markus Bernhard
- Zinovjev Gennady
- Zmeskal Johann
- Zou Shuguang
- Publication venue
- Publication date
- 01/01/2017
- Field of study
Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe
Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world
- Author
- Abad Pedro
- Abbara Suhny
- Abbasi Taimur
- Abbott Brian
- Abdel Aziz Islam Shawky
- Abdulla Jawdat
- Abikhzer Gad
- Abohashem Shady
- Abougabal Mahasen
- Abramson Sandra
- Abrihan Paz
- Acuña Arturo Romero
- Affandi Erwin
- Afzal Muhammad Shehzad
- Agolti Mariela
- Agranovich Svetlana
- Aguadé-Bruix Santiago
- Aguero Roberto Nicolas
- Ahmed Hassan Mohamed Ismail
- Ahmed Taghreed
- Akhter Afroza
- Al Dhuhli Humoud
- Al Kindi Faiza
- Al-Abboud Tarek
- Al-Bulushi Naeema
- Al-Mallah Mouaz
- Alak Maria del Carmen
- Alam Edison
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- Preciado-Gutiérrez Óscar Ulises
- Premaratne Manuja
- Premprabha Teerapon
- Prentice Ryan
- Prior David
- Prior John O.
- Probst Stephan
- Proffit Franck
- Prpic Marina
- Pubul-Nuñez Virginia
- Pugliese Francesca
- Pujol Maria Paula
- Pulizzi Sabina
- Punda Ante
- Pursnani Amit
- Pynda Yaroslav
- Pynda Yaroslav
- Quartuccio Natale
- Quinon Alvin
- Quinta Mayra
- Rabbat Mark
- Radzinschi Alejandro
- Raggi Paolo
- Raggi Paolo
- Raimondi Gustavo
- Rajbanshi Bijoy
- Rajvong Sonexay
- Ramamurti Suresh
- Ramkumar Prasad Guntur
- Rampin Lucia
- Ramírez Nelsy Gonzalez
- Randazzo Michael
- Randazzo Michael J.
- Ranser Sara
- Rawashdeh Mohammad
- Rayo Madrid Juan Ignacio
- Redruello Marcela
- Regaieg Hamza
- Reichmuth Luise
- Repasos Evangelos
- Rey Cristina Rodríguez
- Riaz Musab
- Ricci Fabrizio
- Rich Florence
- Ridley Lloyd
- Robinson Austin
- Robles Kim
- Rocha Ricardo
- Rochela Luis
- Rodrigues Alfredo
- Rodrigues Carlos
- Rodriguez Daniel Calderon
- Rodríguez Cesar
- Rodríguez Marina
- Rodríguez Matías
- Roelants Veronique
- Rofe Christopher
- Roifman Idan
- Rojas Juan Carlos
- Romantini Leila
- Romero Romina Lorena
- Rominger Axel
- Roque Vanegas Hector Bladimir
- Rorie Mark
- Rosales Uvera Sandra Graciela
- Rossini Pierluigi
- Rostami Maryam Tajik
- Rovaletti Federico
- Rozikhodjaeva Gulnora
- Rubini Giuseppe
- Ruiz Diego
- Ruiz Joaquín
- Rumberger John
- Russell Raymond
- Russo Vincenzo
- Rutherford Natalie
- Ryzhkova Daria
- Ríos Raúl Araujo
- Rønnow Sand Niels Peter
- Saadullah Mohammad
- Sabharwal Nikant
- Sabra Philip
- Sacchetti Gian Mauro
- Sadler Diego
- Saifullina Guzaliya
- Saito Masaki
- Sakanyan Mari
- Sakata Sakata Yasushi
- Salehi Hamid
- Salobir Barbara Gužic
- Sambuceti Gianmario
- Samuel Anthony
- San Miguel Lucas
- Sanches Adelina
- Sandoval Sigelinda
- Santana Sara
- Sara da Silva Leonardo
- Sarai Masayoshi
- Saranovic Dragana Sobic
- Sarda-Mantel Laure
- Sasse Alexander
- Sato Daisuke
- Satyr Maryna
- Saunders Connor
- Saxena Sudhir
- Sayman Haluk
- Sazonova Svetlana
- Scarano Massimo
- Scarlett Luke
- Schemmer Mary
- Schmidt Erzsébet
- Schneider Roman P.
- Schoepf U. Joseph
- Schofield Rebecca
- Scholte Arthur
- Scholtens Asbjørn
- Scholtz Leonie
- Schvartzman Paulo
- Sciagrà Roberto
- Sebikali Mugisha Julius
- Sekar Ramkumar
- Sellem Ali
- Semple Thomas
- Seneviratne Sujith
- Sengupta Shantanu
- Senra Tiago
- Sereegotov Erdenechimeg
- Sergienko Vladimir
- Sergienko Vladimir
- Sevilla Ana
- Shaaban Mahmoud
- Shah Nishant
- Shah Nishant R.
- Shah Samir
- Shalev Aryeh
- Shanbhag Sujata
- Sharma Gaurav
- Sharma Naveen
- Shaw Leslee J.
- Shaw Leslee J.
- Shayani Steven
- Shetty Deepa
- Shiozaki Afonso
- Shiraishi Shinya
- Shirani Jamshid
- Shirka Ervina
- Shivaram Pushpa
- Shrestha Ganesh
- Shulman Jonathan
- Shurupova Irina
- Sierra-Galan Lilia M.
- Sierra-Galan Lilia M.
- Sigman Steven
- Silva Fábio Martins
- Simanek Milan
- Simon Mitch
- Simonsson Magnus
- Singh Bhanupriya
- Singh Santosh
- Sinitsyn Valentin
- Siqueira Cristiano
- Siu Silvia
- Slart Riemer
- Slim Ahmad
- Small Gary
- Smanio Paola
- Smith Alexandra
- Smith David
- So Young
- Soares Carlos Eduardo
- Soeriadi Erwin Affandi
- Solanki Vijay
- Solari Lucrecia
- Soldat-Stankovic Valentina
- Soli Idrissa Adamou
- Soman Prem
- Sood Aditya
- Sood Ashwani
- Sperandio Massimiliano
- Spiro Bernardo
- Srichai-Parsia Monvadi Barbara
- Stan Claudiu Adrian
- Stankovic Sinisa
- Stanton Tony
- Stavrou Petros
- Stefanelli Antonella
- Steffensen Rolf
- Strada Bruno
- Streeter James
- Strouhal Peter
- Stuart Murch
- Stubbs Michael
- Subedi Deepak
- Sueldo Claudio Pereyra
- Sun Kai
- Suwa Yoshinobu
- Swainson Ian
- Syawaluddin Hilman
- Syed Ghulam
- Szilveszter Balint
- T Albert
- Tacher Vania
- Tag Naima
- Takanami Kentaro
- Takehana Kazuya
- Taki Junichi
- Taleb Sara
- Tamaki Nagara
- Tandon Vikas
- Tang Gongshun
- Tang Jeanelle Margareth
- Taniguchi Yasuyo
- Taubman Kim
- Tawakol Ahmed
- Taylor Andrew
- Tecson Bettina
- Teragawa Hiroki
- Theng Youdaline
- Thientunyakit Tanyaluck
- Thimister Paul
- Thomas Dustin
- Thomas Paul
- Thomassen Anders
- Thompson Randall
- Thu Phyo Si
- To Andrew
- Tomas Miguel Santaularia
- Tomizawa Nobuo
- Topping William
- Torbet Tara
- Torreao Jorge
- Torres Rafael
- Traverso Sonia
- Traverzo Sonia Simona
- Trifonova Tatjana
- Trinidad Desiree
- Trivedi Adwait
- Tsujita Kenichi
- Tweed Katharine
- Udugama Chandraguptha
- Uellendahl Marly
- Ullery Shawn
- Umeji Kyoko
- Unger Steven
- Unzek Samuel
- Upton Anthony
- Uretsky Seth
- Uson Kristine Joy
- Ussov Wladimir Yurievich
- Uusitalo Valtteri
- Uy Mila
- Vajauskas Donatas
- Vakhromeeva Margarita
- Valiullina Nailya
- Vallejo Enrique
- Valles Mario
- Vallurupalli Srikanth
- Vallée Jean-Paul
- Valsamaki Pipitsa
- Vamadevan Shankar
- Van Asperen Erik-Jan
- Van De Heyning Caroline M.
- Van Gaal William
- Van Pelt Niels
- Vangu Mboyo
- Vargas Luis Salazar
- Vasquez Andres
- Vavlukis Marija
- Velez Mayra Sanchez
- Veltman Niels
- Ventroni Guido
- Vergel Damiana
- Verjans Johan
- Verma Atul
- Verma Vikas
- Verschure Derk
- Veríssimo Otávia
- Villines Todd C.
- Villines Todd C.
- Vitola Joao V.
- Vitola Joao V.
- Vondrak Andrej
- Voutnis Demetrius
- Vuuren Magritha Jv
- Várady Edit
- Vázquez Manuel Castillo
- Wagenaar Nils
- Wakabayashi Yasushi
- Waller Alfonso
- Waltrick Roberto
- Wang Ellen
- Wang Jian
- Wang Ximing
- Wang Yifan
- Wang Yining
- Wang Zhao-Qian
- Ward Parker
- Wayne Victor
- Weihmuller Juan Sebastian
- Weir-Mccall Jonathan
- Weiss Konrad
- Weissman Gaby
- Wesbey George
- White James
- White Kelly
- Williams Michelle C.
- Williams Michelle C.
- Wilson Peter
- Winchester David
- Winchester David
- Wolcan Juan
- Wolinsky David
- Won Kyoung Sook
- Wong David
- Wong Kirby
- Wu Jiang
- Wu Zhifang
- Xia Liming
- Xiao Jiangxi
- Xu Lei
- Xu Zhuoran
- Yamada Shinichiro
- Yamazaki Shinya
- Yang Youyou
- Yew Min Sen
- Yin Wu
- Yoneyama Tatsuya
- Yost Sandra
- Young Calum
- Younger John
- Younis Muhammad Numair
- Yu Jianqun
- Yuan Li
- Zaid Eed Abu
- Zakavi Seyed Rasoul
- Zapparoli Marcello
- Zavadovsky Konstantin
- Zeffiro Susana
- Zeidán Nahla
- Zerahn Bo
- Zgaljardic Michael
- Zhang Longjiang
- Zhang Tong
- Zhang Xiaoli
- Zhang Yong-Gao
- Zhu Li
- Zhuravlev Kirill
- Zoboli Stefania
- Zukotynski Katherine
- Zuluaga Alejandro
- Øvrehus Kristian Altern
- Štalc Monika
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic.
Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality.
Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States.
Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis.
Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
- Author
- Abantanga FA
- Abatli SJ
- Abbas W
- Abbo O
- Abd Elmenam M
- Abd Razak RB
- Abdelbaqi R
- Abdelhady DS
- Abdelhafez MOM
- Abdelhamid SS
- Abdelmaksoud S
- Abdelmoumen R
- Abdelmutalib F
- Abdul-Mumin A
- Abduljawad FM
- Abdullah F
- Abdulraheem N
- Abdulrahman A
- Abdulsalam MA
- Abdunomonovich DA
- Abib SDCV
- Aboelela A
- Abouheba M
- Abrahamsson K
- Abu Ajwa AE
- Abu Al-saleem HSH
- Abu Alamrain AA
- Abu Bakar AH
- Abu Farha MS
- Abu Jamie N
- Abu Jamie YMK
- Abu Jayyab M
- Abu Mayaleh A
- Abu Shiha E
- Abu Za'nouneh FJ
- Abu-Nejmah F
- Abuajaila A
- Abuattaya AA
- Abubakar AM
- Abueideh A
- Abuhayyeh HA
- Abuhlega MA
- Abukhalaf S
- Abumunshar AA
- Acuna G
- Adams S
- Adamu S
- Adanan MFSBM
- Adawi I
- Adawi S
- Adawy A
- Ade-Ajayi N
- Adegboyega R
- Ademuyiwa A
- Adesanya O
- Adhiwidjaja CF
- Adofo-Ansong N
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- Ajao EA
- Ajiboye OS
- Ajrami Y
- Akan ME
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- Al Massry NA
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- Dagilyte R
- Daher AP
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- do Nascimento SD
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- Dosselman LJ
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- Yaghi DH
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- Yang H-B
- Yanis AH
- Yao Y
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- Yeniay AO
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- Yong F
- Youn JK
- Yousuf H
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- Yuldashev RZ
- Yunus A
- Zaghlol LY
- Zain M
- Zaman ASK
- Zanellato JB
- Zea-Salazar LE
- Zeinelabdeen A
- Zelada JA
- Zhao X
- Zhu J
- Zhu L
- Zidan M
- Zivanovic D
- Zreeg DAS
- Zurikat RO
- Zvizdic N
- Zvizdic Z
- Publication venue
- ELSEVIER SCIENCE INC
- Publication date
- 24/07/2021
- Field of study
Background: Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. // Methods: We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung's disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. // Findings: We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung's disease) from 264 hospitals (89 in high-income countries, 166 in middle-income countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in low-income countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. // Interpretation: Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between low-income, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030
Elliptic flow of muons from heavy-flavour hadron decays at forward rapidity in Pb-Pb collisions at root s(NN)=2.76TeV
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aiola Salvatore
- Akindinov Alexander
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alfaro Molina Jose Ruben
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski Jonas
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Armesto Perez Nestor
- Arnaldi Roberta
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Bach Matthias Jakob
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Baldisseri Alberto
- Baltasar Dos Santos Pedrosa Fernando
- Baral Rama Chandra
- Barbano Anastasia Maria
- Barbera Roberto
- Barile Francesco
- Barnafoldi Gergely Gabor
- Barnby Lee Stuart
- Bartalini Paolo
- Barth Klaus
- Bartke Jerzy Gustaw
- Bartsch Esther
- Bashir Butt Jamila
- Basile Maurizio
- Bastid Nicole
- Basu Sumit
- Bathen Bastian
- Batigne Guillaume
- Batista Camejo Arianna
- Batyunya Boris
- Batzing Paul Christoph
- Bearden Ian Gardner
- Beck Hans
- Bedda Cristina
- Behera Nirbhay Kumar
- Belikov Iouri
- Bellini Francesca
- Bello Martinez Hector
- Bellwied Rene
- Belmont Iii Ronald John
- Belmont Moreno Ernesto
- Belyaev Vladimir
- Bencedi Gyula
- Beole Stefania
- Berceanu Ionela
- Bercuci Alexandru
- Berdnikov Yaroslav
- Berenyi Daniel
- Bertens Redmer Alexander
- Berzano Dario
- Betev Latchezar
- Bhasin Anju
- Bhat Inayat Rasool
- Bhati Ashok Kumar
- Bhattacharjee Buddhadeb
- Bhom Jihyun
- Bianchi Livio
- Bianchi Nicola
- Bianchin Chiara
- Bielcik Jaroslav
- Bielcikova Jana
- Bilandzic Ante
- Biswas Rathijit
- Biswas Saikat
- Bjelogrlic Sandro
- Blair Justin Thomas
- Blanco Fernando
- Blau Dmitry
- Blume Christoph
- Bock Friederike
- Boettger Stefan
- Bogdanov Alexey
- Boggild Hans
- Boldizsar Laszlo
- Bombara Marek
- Book Julian Heinz
- Borel Herve
- Borissov Alexander
- Borri Marcello
- Bossu Francesco
- Botta Elena
- Braun-Munzinger Peter
- Bregant Marco
- Breitner Timo Gunther
- Broker Theo Alexander
- Browning Tyler Allen
- Broz Michal
- Brucken Erik Jens
- Bruna Elena
- Bruno Giuseppe Eugenio
- Budnikov Dmitry
- Buesching Henner
- Bufalino Stefania
- Buncic Predrag
- Busch Oliver
- Buthelezi Edith Zinhle
- Buxton Jesse Thomas
- Cabanillas Noris Juan Carlos
- Caffarri Davide
- Cai Xu
- Caines Helen Louise
- Calero Diaz Liliet
- Caliva Alberto
- Calvo Villar Ernesto
- Camerini Paolo
- Carena Francesco
- Carena Wisla
- Carnesecchi Francesca
- Castillo Castellanos Javier Ernesto
- Castro Andrew John
- Casula Ester Anna Rita
- Cavicchioli Costanza
- Ceballos Sanchez Cesar
- Cepila Jan
- Cerello Piergiorgio
- Cerkala Jakub
- Chang Beomsu
- Chapeland Sylvain
- Chartier Marielle
- Charvet Jean-Luc Fernand
- Chattopadhyay Subhasis
- Chattopadhyay Sukalyan
- Chelnokov Volodymyr
- Cherney Michael Gerard
- Cheshkov Cvetan Valeriev
- Cheynis Brigitte
- Chibante Barroso Vasco Miguel
- Chochula Peter
- Choi Kyungeon
- Chojnacki Marek
- Choudhury Subikash
- Christakoglou Panagiotis
- Christensen Christian Holm
- Christiansen Peter
- Chujo Tatsuya
- Chung Suh-Urk
- Cicalo Corrado
- Cifarelli Luisa
- Cindolo Federico
- Cleymans Jean Willy Andre
- Colamaria Fabio Filippo
- Colella Domenico
- Collu Alberto
- Colocci Manuel
- Conesa Balbastre Gustavo
- Conesa Del Valle Zaida
- Connors Megan Elizabeth
- Contreras Nuno Jesus Guillermo
- Cormier Thomas Michael
- Corrales Morales Yasser
- Correia Zanoli Henrique Jose
- Cortes Maldonado Ismael
- Cortese Pietro
- Cosentino Mauro Rogerio
- Costa Filippo
- Crochet Philippe
- Cruz Albino Rigoberto
- Cuautle Flores Eleazar
- Cunqueiro Mendez Leticia
- D'Erasmo Ginevra
- Dahms Torsten
- Dainese Andrea
- Danu Andrea
- Das Debasish
- Das Indranil
- Das Supriya
- Dash Ajay Kumar
- Dash Sadhana
- De Caro Annalisa
- De Cataldo Giacinto
- De Cuveland Jan
- De Falco Alessandro
- De Gruttola Daniele
- De Marco Nora
- De Pasquale Salvatore
- De Sudipan
- Deisting Alexander
- Deloff Andrzej
- Denes Ervin Sandor
- Di Bari Domenico
- Di Mauro Antonio
- Di Nezza Pasquale
- Diaz Corchero Miguel Angel
- Dietel Thomas
- Dillenseger Pascal
- Diozcora Vargas Trevino Aurora
- Divia Roberto
- Djuvsland Oeystein
- Dobrigkeit Chinellato David
- Dobrin Alexandru Florin
- Dobrowolski Tadeusz Antoni
- Domenicis Gimenez Diogenes
- Donigus Benjamin
- Dordic Olja
- Drozhzhova Tatiana
- Dubey Anand Kumar
- Dubla Andrea
- Ducroux Laurent
- Dupieux Pascal
- Ehlers Iii Raymond James
- Elia Domenico
- Engel Heiko
- Epple Eliane
- Erazmus Barbara Ewa
- Erdemir Irem
- Erhardt Filip
- Espagnon Bruno
- Estienne Magali Danielle
- Esumi Shinichi
- Eum Jongsik
- Evans David
- Evdokimov Sergey
- Eyyubova Gyulnara
- Fabbietti Laura
- Fabris Daniela
- Faivre Julien
- Fantoni Alessandra
- Fasel Markus
- Feldkamp Linus
- Felea Daniel
- Feliciello Alessandro
- Feofilov Grigorii
- Ferencei Jozef
- Fernandez Tellez Arturo
- Ferreira Natal Da Luz Pedro Hugo
- Ferretti Alessandro
- Festanti Andrea
- Feuillard Victor Jose Gaston
- Figiel Jan
- Filchagin Sergey
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- Yaldo Chris G
- Yang Hongyan
- Yang Ping
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- Yin Zhongbao
- Yokoyama Hiroki
- Yoo In-Kwon
- Yurchenko Volodymyr
- Yushmanov Igor
- Zaborowska Anna
- Zaccolo Valentina
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- Zampolli Chiara
- Zaporozhets Sergey
- Zardoshti Nima
- Zarochentsev Andrey
- Zavada Petr
- Zavyalov Nikolay
- Zbroszczyk Hanna Paulina
- Zgura Sorin Ion
- Zhalov Mikhail
- Zhang Chunhui
- Zhang Haitao
- Zhang Xiaoming
- Zhang Yonghong
- Zhang Zuman
- Zhao Chengxin
- Zhigareva Natalia
- Zhou Daicui
- Zhou You
- Zhou Zhuo
- Zhu Hongsheng
- Zhu Jianhui
- Zichichi Antonino
- Zimmermann Alice
- Zimmermann Markus Bernhard
- Zinovjev Gennady
- Zyzak Maksym
- Publication venue
- Publication date
- 11/07/2015
- Field of study
The elliptic flow, v(2), of muons from heavy-flavour hadron decays at forward rapidity (2.5 <y <4) is measured in Pb-Pb collisions at root s(NN)= 2.76TeVwith the ALICE detector at the LHC. The scalar product, two- and four-particle Q cumulants and Lee-Yang zeros methods are used. The dependence of the v(2) of muons from heavy-flavour hadron decays on the collision centrality, in the range 0-40%, and on transverse momentum, p(T), is studied in the interval 3 <p(T)<10 GeV/c. A positive v(2) is observed with the scalar product and two-particle Q cumulants in semi-central collisions (10-20% and 20-40% centrality classes) for the p(T) interval from 3 to about 5GeV/c with a significance larger than 3 sigma, based on the combination of statistical and systematic uncertainties. The v(2) magnitude tends to decrease towards more central collisions and with increasing pT. It becomes compatible with zero in the interval 6 <p(T)<10 GeV/c. The results are compared to models describing the interaction of heavy quarks and open heavy-flavour hadrons with the high-density medium formed in high-energy heavy-ion collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V.Peer reviewe
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