226 research outputs found

    The Impact of Parameterized Convection on the Simulation of Crop Processes

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    Global climate and weather models are a key tool for the prediction of future crop productivity, but they all rely on parameterizations of atmospheric convection, which often produce significant biases in rainfall characteristics over the tropics. The authors evaluate the impact of these biases by driving the General Large Area Model for annual crops (GLAM) with regional-scale atmospheric simulations of one cropping season over West Africa at different resolutions, with and without a parameterization of convection, and compare these with a GLAM run driven by observations. The parameterization of convection produces too light and frequent rainfall throughout the domain, as compared with the short, localized, high-intensity events in the observations and in the convection-permitting runs. Persistent light rain increases surface evaporation, and much heavier rainfall is required to trigger planting. Planting is therefore delayed in the runs with parameterized convection and occurs at a seasonally cooler time, altering the environmental conditions experienced by the crops. Even at high resolutions, runs driven by parameterized convection underpredict the small-scale variability in yields produced by realistic rainfall patterns. Correcting the distribution of rainfall frequencies and intensities before use in crop models will improve the process-based representation of the crop life cycle, increasing confidence in the predictions of crop yield. The rainfall biases described here are a common feature of parameterizations of convection, and therefore the crop-model errors described are likely to occur when using any global weather or climate model, thus remaining hidden when using climate-model intercomparisons to evaluate uncertainty

    Constraints on the braneworld from compact stars

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    According to the braneworld idea, ordinary matter is confined on a three-dimensional space (brane) that is embedded in a higher-dimensional space-time where gravity propagates. In this work, after reviewing the limits coming from general relativity, finiteness of pressure and causality on the brane, we derive observational constraints on the braneworld parameters from the existence of stable compact stars. The analysis is carried out by solving numerically the brane-modified Tolman–Oppenheimer–Volkoff equations, using different representative equations of state to describe matter in the star interior. The cases of normal dense matter, pure quark matter and hybrid matter are considered.info:eu-repo/semantics/publishedVersio

    DNA cruciform arms nucleate through a correlated but non-synchronous cooperative mechanism

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    Inverted repeat (IR) sequences in DNA can form non-canonical cruciform structures to relieve torsional stress. We use Monte Carlo simulations of a recently developed coarse-grained model of DNA to demonstrate that the nucleation of a cruciform can proceed through a cooperative mechanism. Firstly, a twist-induced denaturation bubble must diffuse so that its midpoint is near the centre of symmetry of the IR sequence. Secondly, bubble fluctuations must be large enough to allow one of the arms to form a small number of hairpin bonds. Once the first arm is partially formed, the second arm can rapidly grow to a similar size. Because bubbles can twist back on themselves, they need considerably fewer bases to resolve torsional stress than the final cruciform state does. The initially stabilised cruciform therefore continues to grow, which typically proceeds synchronously, reminiscent of the S-type mechanism of cruciform formation. By using umbrella sampling techniques we calculate, for different temperatures and superhelical densities, the free energy as a function of the number of bonds in each cruciform along the correlated but non-synchronous nucleation pathways we observed in direct simulations.Comment: 12 pages main paper + 11 pages supplementary dat

    Cosmic Physics: The High Energy Frontier

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    Cosmic rays have been observed up to energies 10810^8 times larger than those of the best particle accelerators. Studies of astrophysical particles (hadrons, neutrinos and photons) at their highest observed energies have implications for fundamental physics as well as astrophysics. Thus, the cosmic high energy frontier is the nexus to new particle physics. This overview discusses recent advances being made in the physics and astrophysics of cosmic rays and cosmic gamma-rays at the highest observed energies as well as the related physics and astrophysics of very high energy cosmic neutrinos. These topics touch on questions of grand unification, violation of Lorentz invariance, as well as Planck scale physics and quantum gravity.Comment: Topical Review Paper to be published in the Journal of Physics G, 50 page

    Search for anomalous t t-bar production in the highly-boosted all-hadronic final state

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    A search is presented for a massive particle, generically referred to as a Z', decaying into a t t-bar pair. The search focuses on Z' resonances that are sufficiently massive to produce highly Lorentz-boosted top quarks, which yield collimated decay products that are partially or fully merged into single jets. The analysis uses new methods to analyze jet substructure, providing suppression of the non-top multijet backgrounds. The analysis is based on a data sample of proton-proton collisions at a center-of-mass energy of 7 TeV, corresponding to an integrated luminosity of 5 inverse femtobarns. Upper limits in the range of 1 pb are set on the product of the production cross section and branching fraction for a topcolor Z' modeled for several widths, as well as for a Randall--Sundrum Kaluza--Klein gluon. In addition, the results constrain any enhancement in t t-bar production beyond expectations of the standard model for t t-bar invariant masses larger than 1 TeV.Comment: Submitted to the Journal of High Energy Physics; this version includes a minor typo correction that will be submitted as an erratu

    New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

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    Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic traits, we performed meta-analyses of 21 genome-wide association studies informative for fasting glucose, fasting insulin and indices of beta-cell function (HOMA-B) and insulin resistance (HOMA-IR) in up to 46,186 nondiabetic participants. Follow-up of 25 loci in up to 76,558 additional subjects identified 16 loci associated with fasting glucose and HOMA-B and two loci associated with fasting insulin and HOMA-IR. These include nine loci newly associated with fasting glucose (in or near ADCY5, MADD, ADRA2A, CRY2, FADS1, GLIS3, SLC2A2, PROX1 and C2CD4B) and one influencing fasting insulin and HOMA-IR (near IGF1). We also demonstrated association of ADCY5, PROX1, GCK, GCKR and DGKB-TMEM195 with type 2 diabetes. Within these loci, likely biological candidate genes influence signal transduction, cell proliferation, development, glucose-sensing and circadian regulation. Our results demonstrate that genetic studies of glycemic traits can identify type 2 diabetes risk loci, as well as loci containing gene variants that are associated with a modest elevation in glucose levels but are not associated with overt diabetes
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