Alterações químicas e histológicas em mandiocas armazenadas das cultivares catarina amarela e catarina branca

A pesquisa teve por objetivo avaliar e comparar as alterações químicas e histológicas ocorridas após o armazenamento das raízes de mandioca das cultivares Catarina Amarela e Catarina Branca. As raízes cultivadas no Instituto Agronômico do Paraná foram colhidas aos 10 meses de idade, sendo a parte aérea da planta podada 30 dias antes da colheita, estas foram armazenadas por 5 dias e submetidas à avaliação da deterioração fisiológica, teor de umidade, atividades de polifenoloxidase e peroxidase, teor de compostos fenólicos totais, detecção de peróxido de hidrogênio, teor de carotenóides totais, celulose, lignina, além de avaliações histológicas. Após o armazenamento as cultivares apresentaram alterações no teor de umidade, atividade de peroxidase, compostos fenólicos totais e lignina. Ambas cultivares não apresentaram atividade de polifenoloxidase. Foram observadas alterações histológicas, sendo esta mais pronunciada na cultivar Catarina Amarela.  Deste modo, as cultivares Catarina Amarela e Catarina Branca sofrem alterações químicas e histológicas após o armazenamento, sendo a Catarina Branca a mais resistente às alterações pós-colheita.A pesquisa teve por objetivo avaliar e comparar as alterações químicas e histológicas ocorridas após o armazenamento das raízes de mandioca (Manihot esculenta Crantz) das cultivares Catarina Amarela e Catarina Branca. A parte aérea da planta foi podada 30 dias antes da colheita e as raízes, cultivadas no Instituto Agronômico do Paraná, foram colhidas aos 10 meses de idade, armazenadas por 5 dias e submetidas à avaliação da deterioração fisiológica, teor de umidade, atividades de polifenoloxidase e peroxidase, teor de compostos fenólicos totais, detecção de peróxido de hidrogênio, teor de carotenóides totais, celulose, lignina, além de avaliações histológicas. Após o armazenamento as cultivares sofreram deterioração fisiológica e apresentaram alterações no teor de umidade, atividade de peroxidase, compostos fenólicos totais e lignina. Ambas cultivares não apresentaram atividade de polifenoloxidase. Foram observadas alterações histológicas, sendo esta mais pronunciada na cultivar Catarina Amarela. Deste modo, as cultivares Catarina Amarela e Catarina Branca sofrem alterações químicas e histológicas após o armazenamento, sendo a Catarina Branca a mais resistente às alterações pós-colheita.The research aimed evaluate and compare chemical and histological changes occurring after harvest of cassava roots (Manihot esculenta Crantz) of cultivars Catarina Amarela and Catarina Branca. The cassava grown at Instituto Agronômico do Paraná - Londrina-BR, had the foliage of the plants cut 30 days before harvest, and roots were collected at 10 months of age. The roots were stored for 5 days at environment conditions and submitted to evaluation of the degree of physiological deterioration, moisture content, activities of the enzymes polyphenoloxidase and peroxidase, content of phenolic compounds, detection and localization of hydrogen peroxide, composition in carotenoids, cellulose, lignin, and microscopy of the parenchyma. After storage the cultivars presented physiological deterioration and changes in moisture content, activities of peroxidase, content of phenolic compounds and lignin. Both cultivars showed no polyphenoloxidase activity. Alterations histological were observed, which is more pronounced in Catarina Amarela. The cultivars Catarina Amarela and Catarina Branca presents chemical and histological changes after storage, and Catarina Branca the most resistant to post-harvest changes

Optical Properties And Antiangiogenic Activity Of A Chalcone Derivate

Chalcones and their derivatives exhibit numerous pharmacological activities such as antibacterial, antifungal, cytotoxic, antinociceptive and anti-inflammatory. Recently, they have been assessed aiming for novel application in nonlinear optics and in the treatment of immune diseases and cancers. In this study, we investigate the optical properties of synthetic chalcona 1E,4E-1-(4-chlorophenyl)-5-(2,6,6-trimethylcyclohexen-1-yl)penta-1,4-dien-3-one (CAB7β) and its antiangiogenic potential using the chorioallantoic membrane (CAM) with the S180 sarcoma cell line. Experimental and theoretical results show intense absorption in the UVA-UVC region, which is associated with a π → π* transition with intramolecular charge transfer from the trimethyl-cyclohexen-1-yl ring to the chlorophenyl ring. Quantum chemical calculations of the first hyperpolarizability, accounting for both solvent and frequency dispersion effects, are in very good concordance with hyper-Rayleigh scattering measurements. In addition, two-photon absorption allowed band centered at 650 nm was observed. Concerning antiangiogenic activity, CAB7β causes a significant reduction in the total number, junctions, length and caliber of blood vessels stimulated by S180 cells reducing the presence of blood vessels, inflammatory cells and others elements related to angiogenic process. It is found that CAB7β is a versatile compound and a promising candidate for linear and nonlinear optical applications, in therapy against sarcoma and phototherapy

Search for the standard model Higgs boson decaying into two photons in pp collisions at sqrt(s)=7 TeV

A search for a Higgs boson decaying into two photons is described. The analysis is performed using a dataset recorded by the CMS experiment at the LHC from pp collisions at a centre-of-mass energy of 7 TeV, which corresponds to an integrated luminosity of 4.8 inverse femtobarns. Limits are set on the cross section of the standard model Higgs boson decaying to two photons. The expected exclusion limit at 95% confidence level is between 1.4 and 2.4 times the standard model cross section in the mass range between 110 and 150 GeV. The analysis of the data excludes, at 95% confidence level, the standard model Higgs boson decaying into two photons in the mass range 128 to 132 GeV. The largest excess of events above the expected standard model background is observed for a Higgs boson mass hypothesis of 124 GeV with a local significance of 3.1 sigma. The global significance of observing an excess with a local significance greater than 3.1 sigma anywhere in the search range 110-150 GeV is estimated to be 1.8 sigma. More data are required to ascertain the origin of this excess.Comment: Submitted to Physics Letters

Search for anomalous t t-bar production in the highly-boosted all-hadronic final state

A search is presented for a massive particle, generically referred to as a Z', decaying into a t t-bar pair. The search focuses on Z' resonances that are sufficiently massive to produce highly Lorentz-boosted top quarks, which yield collimated decay products that are partially or fully merged into single jets. The analysis uses new methods to analyze jet substructure, providing suppression of the non-top multijet backgrounds. The analysis is based on a data sample of proton-proton collisions at a center-of-mass energy of 7 TeV, corresponding to an integrated luminosity of 5 inverse femtobarns. Upper limits in the range of 1 pb are set on the product of the production cross section and branching fraction for a topcolor Z' modeled for several widths, as well as for a Randall--Sundrum Kaluza--Klein gluon. In addition, the results constrain any enhancement in t t-bar production beyond expectations of the standard model for t t-bar invariant masses larger than 1 TeV.Comment: Submitted to the Journal of High Energy Physics; this version includes a minor typo correction that will be submitted as an erratu

Measurement of the Lambda(b) cross section and the anti-Lambda(b) to Lambda(b) ratio with Lambda(b) to J/Psi Lambda decays in pp collisions at sqrt(s) = 7 TeV

The Lambda(b) differential production cross section and the cross section ratio anti-Lambda(b)/Lambda(b) are measured as functions of transverse momentum pt(Lambda(b)) and rapidity abs(y(Lambda(b))) in pp collisions at sqrt(s) = 7 TeV using data collected by the CMS experiment at the LHC. The measurements are based on Lambda(b) decays reconstructed in the exclusive final state J/Psi Lambda, with the subsequent decays J/Psi to an opposite-sign muon pair and Lambda to proton pion, using a data sample corresponding to an integrated luminosity of 1.9 inverse femtobarns. The product of the cross section times the branching ratio for Lambda(b) to J/Psi Lambda versus pt(Lambda(b)) falls faster than that of b mesons. The measured value of the cross section times the branching ratio for pt(Lambda(b)) > 10 GeV and abs(y(Lambda(b))) < 2.0 is 1.06 +/- 0.06 +/- 0.12 nb, and the integrated cross section ratio for anti-Lambda(b)/Lambda(b) is 1.02 +/- 0.07 +/- 0.09, where the uncertainties are statistical and systematic, respectively.Comment: Submitted to Physics Letters

Search for new physics in events with opposite-sign leptons, jets, and missing transverse energy in pp collisions at sqrt(s) = 7 TeV

A search is presented for physics beyond the standard model (BSM) in final states with a pair of opposite-sign isolated leptons accompanied by jets and missing transverse energy. The search uses LHC data recorded at a center-of-mass energy sqrt(s) = 7 TeV with the CMS detector, corresponding to an integrated luminosity of approximately 5 inverse femtobarns. Two complementary search strategies are employed. The first probes models with a specific dilepton production mechanism that leads to a characteristic kinematic edge in the dilepton mass distribution. The second strategy probes models of dilepton production with heavy, colored objects that decay to final states including invisible particles, leading to very large hadronic activity and missing transverse energy. No evidence for an event yield in excess of the standard model expectations is found. Upper limits on the BSM contributions to the signal regions are deduced from the results, which are used to exclude a region of the parameter space of the constrained minimal supersymmetric extension of the standard model. Additional information related to detector efficiencies and response is provided to allow testing specific models of BSM physics not considered in this paper.Comment: Replaced with published version. Added journal reference and DO

Search for a Higgs boson in the decay channel H → ZZ(*) → qq̅ l−l+ in pp collisions at √s̅ = 7 TeV

Peer reviewe

Severe early onset preeclampsia: short and long term clinical, psychosocial and biochemical aspects

Preeclampsia is a pregnancy specific disorder commonly defined as de novo hypertension and proteinuria after 20 weeks gestational age. It occurs in approximately 3-5% of pregnancies and it is still a major cause of both foetal and maternal morbidity and mortality worldwide1. As extensive research has not yet elucidated the aetiology of preeclampsia, there are no rational preventive or therapeutic interventions available. The only rational treatment is delivery, which benefits the mother but is not in the interest of the foetus, if remote from term. Early onset preeclampsia (<32 weeks’ gestational age) occurs in less than 1% of pregnancies. It is, however often associated with maternal morbidity as the risk of progression to severe maternal disease is inversely related with gestational age at onset2. Resulting prematurity is therefore the main cause of neonatal mortality and morbidity in patients with severe preeclampsia3. Although the discussion is ongoing, perinatal survival is suggested to be increased in patients with preterm preeclampsia by expectant, non-interventional management. This temporising treatment option to lengthen pregnancy includes the use of antihypertensive medication to control hypertension, magnesium sulphate to prevent eclampsia and corticosteroids to enhance foetal lung maturity4. With optimal maternal haemodynamic status and reassuring foetal condition this results on average in an extension of 2 weeks. Prolongation of these pregnancies is a great challenge for clinicians to balance between potential maternal risks on one the eve hand and possible foetal benefits on the other. Clinical controversies regarding prolongation of preterm preeclamptic pregnancies still exist – also taking into account that preeclampsia is the leading cause of maternal mortality in the Netherlands5 - a debate which is even more pronounced in very preterm pregnancies with questionable foetal viability6-9. Do maternal risks of prolongation of these very early pregnancies outweigh the chances of neonatal survival? Counselling of women with very early onset preeclampsia not only comprises of knowledge of the outcome of those particular pregnancies, but also knowledge of outcomes of future pregnancies of these women is of major clinical importance. This thesis opens with a review of the literature on identifiable risk factors of preeclampsia