221 research outputs found

    Heat management strategies for MSW landfills

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    Heat is a primary byproduct of landfilling of municipal solid waste. Long-term elevated temperatures have been reported for MSW landfills under different operational conditions and climatic regions around the world. A conceptual framework is presented for management of the heat generated in MSW landfills. Three main strategies are outlined: extraction, regulation, and supplementation. Heat extraction allows for beneficial use of the excess landfill heat as an alternative energy source. Two approaches are provided for the extraction strategy: extracting all of the excess heat above baseline equilibrium conditions in a landfill and extracting only a part of the excess heat above equilibrium conditions to obtain target optimum waste temperatures for maximum gas generation. Heat regulation allows for controlling the waste temperatures to achieve uniform distribution at target levels at a landfill facility. Two approaches are provided for the regulation strategy: redistributing the excess heat across a landfill to obtain uniform target optimum waste temperatures for maximum gas generation and redistributing the excess heat across a landfill to obtain specific target temperatures. Heat supplementation allows for controlling heat generation using external thermal energy sources to achieve target waste temperatures. Two approaches are provided for the supplementation strategy: adding heat to the waste mass using an external energy source to increase waste temperatures and cooling the waste mass using an external energy source to decrease waste temperatures. For all strategies, available landfill heat energy is determined based on the difference between the waste temperatures and the target temperatures. Example analyses using data from landfill facilities with relatively low and high heat generation indicated thermal energy in the range of −48.4 to 72.4 MJ/m3 available for heat management. Further modeling and experimental analyses are needed to verify the effectiveness and feasibility of design, installation, and operation of heat management systems in MSW landfills

    Imprisonment and internment: Comparing penal facilities North and South

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    Recent references to the ‘warehouse prison’ in the United States and the prisión-depósito in Latin America seem to indicate that penal confinement in the western hemisphere has converged on a similar model. However, this article suggests otherwise. It contrasts penal facilities in North America and Latin America in terms of six interrelated aspects: regimentation; surveillance; isolation; supervision; accountability; and formalization. Quantitatively, control in North American penal facilities is assiduous (unceasing, persistent and intrusive), while in Latin America it is perfunctory (sporadic, indifferent and cursory). Qualitatively, North American penal facilities produce imprisonment (which enacts penal intervention through confinement), while in Latin America they produce internment (which enacts penal intervention through release). Closely entwined with this qualitative difference are distinct practices of judicial involvement in sentencing and penal supervision. Those practices, and the cultural and political factors that underpin them, represent an interesting starting point for the explanation of the contrasting nature of imprisonment and internment

    The adaptive capacity of maize-based conservation agriculture systems to climate stress in tropical and subtropical environments: A meta-regression of yields

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    Conservation agriculture is widely promoted across sub-Saharan Africa as a sustainable farming practice that enhances adaptive capacity to climate change. The interactions between climate stress, management, and soil are critical to understanding the adaptive capacity of conservation agriculture. Yet conservation agriculture syntheses to date have largely neglected climate, especially the effects of extreme heat. For the sub-tropics and tropics, we use meta-regression, in combination with global soil and climate datasets, to test four hypotheses: (1) that relative yield performance of conservation agriculture improves with increasing drought and temperature stress; (2) that the effects of moisture and temperature stress exposure interact; (3) that the effects of moisture and temperature stress are modified by soil texture; and (4) that crop diversification, fertilizer application rate, or the time since no-till implementation will enhance conservation agriculture performance under climate stress. Our results support the hypothesis that the relative maize yield performance of conservation agriculture improves with increasing drought severity or exposure to high temperatures. Further, there is an interaction of moisture and heat stress on conservation agriculture performance and their combined effect is both non-additive and modified by soil clay content, supporting our second and third hypotheses. Finally, we found only limited support for our fourth hypothesis as (1) increasing nitrogen application rates did not improve the relative performance of conservation agriculture under high heat stress; (2) crop diversification did not notably improve conservation agriculture performance, but did increase its stability with heat stress; and (3) a statistically robust effect of the time since no-till implementation was not evident. Our meta-regression supports the narrative that conservation agriculture enhances the adaptive capacity of maize production in sub-Saharan Africa under drought and/or heat stress. However, in very wet seasons and on clay-rich soils, conservation agriculture yields less compared to conventional practices

    Plasma Markers of Alzheimer's Disease Pathology, Neuronal Injury, and Astrocytic Activation and MRI Load of Vascular Pathology and Neurodegeneration: The SMART-MR Study

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    BACKGROUND: Two of the main causes for dementia are Alzheimer's disease (AD) and vascular pathology, with most patients showing mixed pathology. Plasma biomarkers for Alzheimer's disease-related pathology have recently emerged, including Aβ (amyloid-beta), p-tau (phosphorylated tau), NfL (neurofilament light), and GFAP (glial fibrillary acidic protein). There is a current gap in the literature regarding whether there is an association between these plasma biomarkers with vascular pathology and neurodegeneration. METHODS AND RESULTS: Cross-sectional data from 594 individuals (mean [SD] age: 64 [8] years; 17% female) were included from the SMART-MR (Second Manifestations of Arterial Disease-Magnetic Resonance) study, a prospective cohort study of individuals with a history of arterial disease. Plasma markers were assessed using single molecular array assays (Quanterix). Magnetic resonance imaging markers included white matter hyperintensity volume, presence of infarcts (yes/no), total brain volume, and hippocampal volume assessed on 1.5T magnetic resonance imaging. Linear regressions were performed for each standardized plasma marker with white matter hyperintensity volume, total brain volume, and hippocampal volume as separate outcomes, correcting for age, sex, education, and intracranial volume. Logistic regressions were performed for the presence of lacunar and cortical infarcts. Higher p-tau181 was associated with larger white matter hyperintensity volume ( b per SD increase=0.16 [95% CI, 0.06-0.26], P=0.015). Higher NfL ( b=-5.63, [95% CI, -8.95 to -2.31], P=0.015) was associated with lower total brain volume and the presence of infarcts (odds ratio [OR], 1.42 [95% CI, 1.13-1.78], P=0.039). Higher GFAP levels were associated with cortical infarcts (OR, 1.45 [95% CI, 1.09-1.92], P=0.010). CONCLUSIONS: Plasma biomarkers that have been associated with tau pathology, axonal injury, and astrocytic activation are related to magnetic resonance imagingmarkers of vascular pathology and neurodegeneration in patients with manifest arterial disease

    Acute and Chronic Effects of Particles on Hospital Admissions in New-England

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    Background: Many studies have reported significant associations between exposure to PM2.5PM_{2.5} and hospital admissions, but all have focused on the effects of short-term exposure. In addition all these studies have relied on a limited number of PM2.5PM_{2.5} monitors in their study regions, which introduces exposure error, and excludes rural and suburban populations from locations in which monitors are not available, reducing generalizability and potentially creating selection bias. Methods Using our novel prediction models for exposure combining land use regression with physical measurements (satellite aerosol optical depth) we investigated both the long and short term effects of PM2.5PM_{2.5} exposures on hospital admissions across New-England for all residents aged 65 and older. We performed separate Poisson regression analysis for each admission type: all respiratory, cardiovascular disease (CVD), stroke and diabetes. Daily admission counts in each zip code were regressed against long and short-term PM2.5PM_{2.5} exposure, temperature, socio-economic data and a spline of time to control for seasonal trends in baseline risk. Results: We observed associations between both short-term and long-term exposure to PM2.5PM_{2.5} and hospitalization for all of the outcomes examined. In example, for respiratory diseases, for every10-µg/m3^3 increase in short-term PM2.5PM_{2.5} exposure there is a 0.70 percent increase in admissions (CI = 0.35 to 0.52) while concurrently for every10-µg/m3^3 increase in long-term PM2.5PM_{2.5} exposure there is a 4.22 percent increase in admissions (CI = 1.06 to 4.75). Conclusions: As with mortality studies, chronic exposure to particles is associated with substantially larger increases in hospital admissions than acute exposure and both can be detected simultaneously using our exposure models

    Protein sequences bound to mineral surfaces persist into deep time.

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    Proteins persist longer in the fossil record than DNA, but the longevity, survival mechanisms and substrates remain contested. Here, we demonstrate the role of mineral binding in preserving the protein sequence in ostrich (Struthionidae) eggshell, including from the palaeontological sites of Laetoli (3.8 Ma) and Olduvai Gorge (1.3 Ma) in Tanzania. By tracking protein diagenesis back in time we find consistent patterns of preservation, demonstrating authenticity of the surviving sequences. Molecular dynamics simulations of struthiocalcin-1 and -2, the dominant proteins within the eggshell, reveal that distinct domains bind to the mineral surface. It is the domain with the strongest calculated binding energy to the calcite surface that is selectively preserved. Thermal age calculations demonstrate that the Laetoli and Olduvai peptides are 50 times older than any previously authenticated sequence (equivalent to ~16 Ma at a constant 10°C)

    Habilidades funcionais, nível de actividade, integração na comunidade e saúde em idosos institucionalizados em lar: resultados preliminares

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    São escassos os estudos portugueses que avaliam o nível de funcionalidade, o nível de actividade e a saúde em idosos institucionalizados em lar. Objectivos: Estimar os meses de institucionalização dos idosos e as causas que conduziram à institucionalização em lar, bem como o número de idosos que partilha o seu quarto com outros. Estimar as Habilidades Funcionais dos idosos, o tipo de actividades relatadas, dentro e fora da instituição (Nível de Actividade e Integração na Comunidade) e o grau de saúde (objectiva e subjectiva). Analisar a relação entre estas quatro dimensões e analisar a relação destas com algumas variáveis demográficas (idade, género). Métodos: 35 idosos institucionalizados em lar (idade média=80.20 anos; DP=6.263) completaram o Questionário de Informação Pessoal (QIP; Fernándes-Ballesteros, 1995; Maia et al., 2013). Para a análise dos dados recorremos ao SPSS 21. Resultados: A grande generalidade dos idosos está institucionalizada há mais de 16 meses, por motivos maioritariamente de saúde (65,7%), partilha o quarto com terceiros (71.4%) e é autónoma, não necessitando de ajuda (56.7%) em actividades como o cuidado pessoal, comer, vestir/despir, andar, levantar/deitar. Quando se trata das actividades mais complexas, como a administração de dinheiro, uso do telefone ou ida às compras, o grau de dependência aumenta (27.6% dos sujeitos necessitam de muita ajuda e 35.2% de alguma ajuda). Verifica-se que 72.9% da população está inactiva, visto limitar-se a ver televisão ou a ouvir rádio e apenas 14.3% dos idosos se dedicam a actividades fora da Instituição. Os actos religiosos têm uma larga adesão (88.6%). 79.4% dos idosos reporta problemas de mobilidade e 35.3% problemas de foro psicológico. Verifica-se que 45.7% percepcionam a saúde como má, com as mulheres a percepcionarem a sua saúde mais negativamente do que os homens. Nenhum dos idosos, de ambos os géneros, percepciona a sua saúde como boa ou excelente (0%). A dimensão Nível de Actividade apresenta uma correlação positiva com a dimensão Integração na Comunidade (r=.448*). O género apresenta uma correlação significativa com a dimensão Habilidades Funcionais (rho=.383*) e com a dimensão Saúde (r=.414*). O estado civil apresentou uma correlação positiva com as Habilidades Funcionais (rho=.419*) e o grau de escolaridade apresentou uma correlação negativa e com a dimensão Saúde (r=-.446*). Conclusões: Na nossa amostra a institucionalização é causada maioritariamente devido a problemas de saúde. A maioria dos idosos partilha o seu quarto o que pode afectar a sua intimidade e bem-estar. Apesar da maioria dos idosos ser funcionalmente autónoma, a grande generalidade apresenta uma vida pautada pela inactividade e por fracos laços com o exterior. As mulheres percepcionam a sua saúde mais negativamente do que os homens. Importa assim, desenvolver estratégias que conduzam a um envelhecimento activo destes idosos
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