Efficacy and safety of topical 2% dorzolamide and 0.5% timolol in cases of open angle glaucoma in a tertiary care hospital of East Singhbhum: an observational, prospective and comparative study

Background: Present study was undertaken to evaluate and compare the efficacy and side effects of 2% dorzolamide and 0.5% timolol in patients with open angle glaucoma.Methods: There were 60 randomly selected patients were equally divided into Group I (n=30) and Group II (n=30). Further both groups were divided into IA (n=10), IB (n=20), IIA (n=10) and IIB (n=20). 2% Dorzolamide hydrochloride in Group IA and IIA and 0.5% Timolol maleate in Group IB and IIB was administered for 24 weeks. Patients were evaluated for general and ocular examinations on day of enrolment and then at the end of 1st, 4th, 8th and 24th week. Adverse effects of the drug during study period were also noted. Mean±SD, t value, p value and comparison between groups were analysed by graph pad software.Results: At the end of 24 weeks difference in mean reduction of IOP was not significant with 6.2±1.85mm Hg (Right eye) and 5.55±1.68mm Hg (left eye) and 4.72±2.97mm Hg (Right eye) and 5.37±1.24mm Hg (left eye) in Group IA and Group IIA respectively. At the end of 24 weeks difference in mean reduction of IOP was not significant with 5.06±1.62mm Hg (Right eye) and 4.40±1.96mm Hg (left eye) and 4.30±1.41mm Hg (Right eye) and 4.12±2.08mm Hg (left eye) in Group IB and Group IIB respectively. Fall in both systolic and diastolic blood pressure in both the groups were significant. Both drug regimens were well-tolerated, and no serious drug-related adverse effects were reported.Conclusions: Dorzolamide was more efficacious for reduction of intra ocular pressure, well-tolerated, had low allergic response and had a favourable ocular, cardiovascular and respiratory safety profile than Timolol.

A METHOD AND SYSTEM FOR PROVIDING NON-VISUAL INTERACTION BASED AUTHENTICATION

The present disclosure relates to a method and system for providing non-visual interaction based authentication. Such non-visual interaction based authentication may be provided in any user equipment of a user. Moreover, such non-visual interaction based authentication may be especially provided for specially abled users which utilise accessibility features. The method includes combining non-visual interaction modalities for entering authentication pin discreetly, using buttons or other modalities available on the user equipment

CONTINUOUS AUTHENTICATION USING ACCESSIBILITY SETTINGS AND USAGE ANALYSIS

The present invention discloses a method and system for continuous authentication using accessibility settings and usage analysis which can be used during mobile application login. An Artificial Intelligence (AI) based system, continuously captures and analyses a specially abled user’s behaviour and accessibility settings. The AI would then come up with a risk based score. This risk score will then be used to decide whether or not to skip Multi Factor Authentication (MFA)

Visa Accessible Card (VAC) for specially abled users

The present disclosure relates to a VISA Accessible Cards (VAC) (202) which are designed for easy and secure transactions. The VAC (202) has limited alphabetic characters (102) as the card number, presented in Braille (104) and regular characters for both specially abled people and normal people. The card may not have other details like CVV or expiry date. The card information, such as PAN, expiry date, and CVV may be mapped to the VAC characters and stored securely in a cloud server. Users may choose different engravings on front of the card for easy identification. The card may accompanied by the VAC app, which requires biometric authentication for all transactions

A SYSTEM TO PROVIDE NEXT-GEN ACCESSIBLE PAYMENT CARDS AND METHOD THEREOF

The present disclosure relates to providing a system and method for next generation payment cards which may be conveniently accessed by all, especially the visually impaired customers. It discloses a technique of providing engraved patterns on front side of the payment card to differentiate between the front and back side of the card along with providing a sensory reaction to the user to differentiate between different types of payment cards as specific engraved patterns may be linked to a particular category of payment cards. Further, the back side of the payment card encompasses the 6 unique alphabetic characters which may be embedded in braille as well to facilitate the user to get hold of requisite information by touch interaction only. This technique thus facilitates the financial inclusion of the all the demographics, especially the users with serious visual impairments

A METHOD AND USER EQUIPMENT FOR PROVIDING VIBRATION BASED COMMUNICATION OF SENSITIVE INFORMATION FOR VISUALLY IMPAIRED USERS

The present disclosure relates to a method and user equipment (UE) (102) for providing vibration-based communication of sensitive information for visually impaired users (101). In the present disclosure, initially the UE (102) may receive a request from the visually impaired user (101) to access information present on a virtual card. The UE (102) detects whether the information requested corresponds to be sensitive information. Further, the UE (102) encodes the information into a vibration pattern on confirming it to be sensitive information. Finally, the UE (102) generates the encoded vibration patterns for the visually impaired users (101) to complete the transaction, wherein the visually impaired user (101) refers to an instruction manual to decode the vibration pattern

Study of self drug administration among second professional medical students

Background: Self-medication is very common in our day to day life which is an unhealthy and risky practice. Present study was done to determine the knowledge, attitude and practice among second professional medical students.Methods: A questionnaire related to self-medication with consent was prepared and distributed among the students of second professional. Data was collected and analysed the results expressed as counts and percentages.Results: Total 100 students participated in the study for taking self-medication and was no need to visit the doctor for minor illness. In maximum students, source of information of the drugs used for self-medication pharmacological based and learning process in the college. The source of drug was medical store. Most of the students took self-medication for loose motion and headache followed by cough, cold and fever. Out of total 100 students most of the students took paracetamol tablet as self-medication.Conclusions: This study showed that second professional medical students after studying pharmacological books they do not use any wrong medicine as self-medication. High level of awareness of second professional students has minimized self medication

Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC

Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe