30 research outputs found
Measurement of the cross-section of high transverse momentum vector bosons reconstructed as single jets and studies of jet substructure in pp collisions at √s = 7 TeV with the ATLAS detector
This paper presents a measurement of the cross-section for high transverse momentum W and Z bosons produced in pp collisions and decaying to all-hadronic final states. The data used in the analysis were recorded by the ATLAS detector at the CERN Large Hadron Collider at a centre-of-mass energy of √s = 7 TeV;{\rm Te}{\rm V}4.6\;{\rm f}{{{\rm b}}^{-1}}{{p}_{{\rm T}}}\gt 320\;{\rm Ge}{\rm V}|\eta |\lt 1.9{{\sigma }_{W+Z}}=8.5\pm 1.7$ pb and is compared to next-to-leading-order calculations. The selected events are further used to study jet grooming techniques
The Diversification of the LIM Superclass at the Base of the Metazoa Increased Subcellular Complexity and Promoted Multicellular Specialization
Background: Throughout evolution, the LIM domain has been deployed in many different domain configurations, which has led to the formation of a large and distinct group of proteins. LIM proteins are involved in relaying stimuli received at the cell surface to the nucleus in order to regulate cell structure, motility, and division. Despite their fundamental roles in cellular processes and human disease, little is known about the evolution of the LIM superclass. Results: We have identified and characterized all known LIM domain-containing proteins in six metazoans and three nonmetazoans. In addition, we performed a phylogenetic analysis on all LIM domains and, in the process, have identified a number of novel non-LIM domains and motifs in each of these proteins. Based on these results, we have formalized a classification system for LIM proteins, provided reasonable timing for class and family origin events; and identified lineagespecific loss events. Our analysis is the first detailed description of the full set of LIM proteins from the non-bilaterian species examined in this study. Conclusion: Six of the 14 LIM classes originated in the stem lineage of the Metazoa. The expansion of the LIM superclass at the base of the Metazoa undoubtedly contributed to the increase in subcellular complexity required for the transition from a unicellular to multicellular lifestyle and, as such, was a critically important event in the history of animal multicellularity
Flavor tagged time-dependent angular analysis of the B0s → J/ψϕ decay and extraction of ΔΓs and the weak phase ϕs in ATLAS
A measurement of the B0s→J/ψϕ decay parameters, updated to include flavor tagging is reported using 4.9 fb−¹ of integrated luminosity collected by the ATLAS detector from √s=7 TeV pp collisions recorded in 2011 at the LHC. The values measured for the physical parameters are
ϕs=0.12±0.25(stat)±0.05(syst) rad
ΔΓs=0.053±0.021(stat)±0.010(syst) ps−¹
Γs=0.677±0.007(stat)±0.004(syst) ps−¹
|A∥(0)|2=0.220±0.008(stat)±0.009(syst)
|A0(0)|2=0.529±0.006(stat)±0.012(syst)
δ⊥=3.89±0.47(stat)±0.11(syst) rad
where the parameter ΔΓs is constrained to be positive. The S-wave contribution was measured and found to be compatible with zero. Results for ϕs and ΔΓs are also presented as 68% and 95% likelihood contours, which show agreement with the Standard Model expectations
Monitoring and data quality assessment of the ATLAS liquid argon calorimeter
The liquid argon calorimeter is a key component of the ATLAS detector installed at the CERN Large Hadron Collider. The primary purpose of this calorimeter is the measurement of electron and photon kinematic properties. It also provides a crucial input for measuring jets and missing transverse momentum. An advanced data monitoring procedure was designed to quickly identify issues that would affect detector performance and ensure that only the best quality data are used for physics analysis. This article presents the validation procedure developed during the 2011 and 2012 LHC data-taking periods, in which more than 98% of the proton-proton luminosity recorded by ATLAS at a centre-of-mass energy of 7-8 TeV had calorimeter data quality suitable for physics analysis
Electron reconstruction and identification efficiency measurements with the ATLAS detector using the 2011 LHC proton–proton collision data
Many of the interesting physics processes to be measured at the LHC have a signature involving one or more isolated electrons. The electron reconstruction and identification efficiencies of the ATLAS detector at the LHC have been evaluated using proton–proton collision data collected in 2011 at s√=7 TeV and corresponding to an integrated luminosity of 4.7 fb −1. Tag-and-probe methods using events with leptonic decays of W and Z bosons and J/ψ mesons are employed to benchmark these performance parameters. The combination of all measurements results in identification efficiencies determined with an accuracy at the few per mil level for electron transverse energy greater than 30 GeV
Cervical Syrinx as a Cause of Shoulder Pain in 2 Athletes
The orthopaedic surgeon can be the first specialist to diagnose a neurologic, Many neurologic conditions are first seen with musculoskeletal symptoms. 6,29 The syringomyelic cavity, or syrinx, is formed by a disturbance in the normal cerebral spinal fluid (CSF) flow. The purpose of this communication is to describe the presentation of a syrinx in an athlete and review the presentation, diagnosis, and treatment of syringomyelia for the practicing orthopaedic clinician. A discussion of the pathophysiology behind syrinx development is complex and well debated and, therefore, beyond the scope of this article. The interested reader is referred to a recent review by Greitz. 11 CASE REPORTS Case 1 An 18-year-old, left-hand-dominant, male high school baseball pitcher was seen with arm fatigue and loss of pitch accuracy and velocity. Four months before presentation, he experienced an acute onset of a sharp pain in his left rib cage, which then radiated to his left shoulder and upper extremity while pitching. The patient tolerated the pain for 1 month until he developed changes in pain and temperature sensation in the left upper extremity, highlighted by the patient's description of noting a difference in water temperature from arm to arm while showering. He denied swelling in the extremity, tingling sensations, and nocturnal pain. His medical history included hyperthyroidism. On physical examination, his shoulders were well developed and symmetric, demonstrating full range of motion (ROM) bilaterally with no evidence of scapulothoracic dyskinesis, instability, or labral, acromioclavicular, or rotator cuff abnormalities. There was full ROM of his neck with no tenderness to palpation and a negative Spurling test finding. Manual muscle testing results were normal. Reflexes were brisk, yet symmetric bilaterally, and Hoffman sign results were negative. The examination was notable for only decreased sensation to light touch throughout the entire left upper extremity. Radiograph findings of the neck and shoulder were normal. A cervical spine magnetic resonance imaging (MRI) scan was recommended because of his vague complaints and minor neurologic findings. The MRI demonstrated a Chiari I malformation with a large cystic fluid collection within the spinal cord consistent with a syrin
Cervical Syrinx as a Cause of Shoulder Pain in 2 Athletes
The orthopaedic surgeon can be the first specialist to diagnose a neurologic, Many neurologic conditions are first seen with musculoskeletal symptoms. 6,29 The syringomyelic cavity, or syrinx, is formed by a disturbance in the normal cerebral spinal fluid (CSF) flow. The purpose of this communication is to describe the presentation of a syrinx in an athlete and review the presentation, diagnosis, and treatment of syringomyelia for the practicing orthopaedic clinician. A discussion of the pathophysiology behind syrinx development is complex and well debated and, therefore, beyond the scope of this article. The interested reader is referred to a recent review by Greitz. 11 CASE REPORTS Case 1 An 18-year-old, left-hand-dominant, male high school baseball pitcher was seen with arm fatigue and loss of pitch accuracy and velocity. Four months before presentation, he experienced an acute onset of a sharp pain in his left rib cage, which then radiated to his left shoulder and upper extremity while pitching. The patient tolerated the pain for 1 month until he developed changes in pain and temperature sensation in the left upper extremity, highlighted by the patient's description of noting a difference in water temperature from arm to arm while showering. He denied swelling in the extremity, tingling sensations, and nocturnal pain. His medical history included hyperthyroidism. On physical examination, his shoulders were well developed and symmetric, demonstrating full range of motion (ROM) bilaterally with no evidence of scapulothoracic dyskinesis, instability, or labral, acromioclavicular, or rotator cuff abnormalities. There was full ROM of his neck with no tenderness to palpation and a negative Spurling test finding. Manual muscle testing results were normal. Reflexes were brisk, yet symmetric bilaterally, and Hoffman sign results were negative. The examination was notable for only decreased sensation to light touch throughout the entire left upper extremity. Radiograph findings of the neck and shoulder were normal. A cervical spine magnetic resonance imaging (MRI) scan was recommended because of his vague complaints and minor neurologic findings. The MRI demonstrated a Chiari I malformation with a large cystic fluid collection within the spinal cord consistent with a syrin
Arthroscopically assisted anterior cruciate ligament reconstruction using patellar tendon autograft. Five- to nine-year follow-up evaluation. The American journal of sports medicine 26
ABSTRACT We retrospectively reviewed the results of 97 patients with anterior cruciate ligament reconstructions using an arthroscopically assisted two-incision technique without extraarticular augmentation at an intermediate followup of 5 to 9 years postoperatively. Evaluation included detailed history, physical examination, functional testing, KT-1000 arthrometer measurements, multiple scoring systems, and radiographs. The results were compared with those from a previous study that evaluated a smaller patient cohort using the identical surgical technique at a 2-to 4-year followup. The postoperative physical examination and KT-1000 arthrometer results were statistically improved when compared with preoperative findings. A negative pivot shift result was noted in 83% of patients, and a 1ϩ result in 17% of patients. Seventy percent of patients had Ͻ3 mm difference on manual maximum side-to-side testing. Functional testing averaged less than 2% asymmetry for vertical jump, single-legged hop, or timed 6-meter hop. The Tegner activity level was significantly improved from prereconstruction ratings and similar to preinjury ratings. The mean Lysholm score was 87. The modified Hospital for Special Surgery scores resulted in good or excellent results in 82% of the patients (mean, 87 points). The mean Noyes sports function score was 89, and the reoperation rate for a symptomatic knee flexion contracture was 12%. Ninety-seven percent of patients indicated that they would undergo the procedure again. When compared with this same population at 2 to 4 years, we saw no deterioration in scoring scale results. During the past decade arthroscopically assisted techniques have become accepted methods of reconstructing the ACL. 5-7, 13, 14, 19, 23, 24, 27, 31, 36, 45, 46 Despite many ACLrelated articles in the literature, there are few intermediate-or long-term studies evaluating the results of current, commonly performed techniques. The goals for this minimum 5-year follow-up study were to 1) evaluate clinical stability after this technique, 2) assess function, 3) evaluate patient satisfaction, and 4) compare our results at 5 to 9 years with those from an earlier study of 2 to 4 years' followup of this same surgical technique. 7 MATERIALS AND METHODS Patients who underwent two-incision arthroscopically assisted ACL reconstructions using patellar tendon autograft substitution without extraarticular augmentation between June 1987 and January 1991 were retrospectively reviewed. Patients were identified from a computerized data base maintained by the senior author (BRB), who performed all the surgical procedures. During this period, a variety of 189 knee ligament procedures were performed. Exclusionary criteria included concomitant ex
Dynamic function after anterior cruciate ligament ~ . reconstruction with autologous patellar tendon
ABSTRACT The purpose of this study was to dynamically assess the functional outcome of patients who had undergone successful anterior cruciate ligament reconstruction using an autologous patellar tendon technique and to determine whether their dynamic knee function was related to quadriceps and hamstring muscle strength. The knee kinematics and kinetics of 22 subjects who had undergone anterior cruciate ligament reconstruction (mean age, 27 Ϯ 11 years) and of 22 age-and sex-matched healthy control subjects were determined during various dynamic activities using a computerized motion analysis and force plate system. The differences in the sagittal plane angles and external moments between the two groups during light (walking), moderate (climbing and descending stairs), and higher-demand (jogging, jog and cut, jog and stop) activities were related to isokinetic strength measurements. Although patients who are asymptomatic and functioning well after anterior cruciate ligament reconstruction can perform normally in light activities, higher-demand activities reveal persistent functional adaptations that require further study. Injury to the ACL leads to knee instability and functional adaptations. Although many ACL-deficient patients display little or no visible impairment (primarily because of activity modification), previous studies have shown that patients with ACL deficiencies walk and perform more stressful activities differently than do uninjured subjects, with most of the differences occurring in the sagittal plane angles and moments. The purpose of our study was to determine whether functional adaptations during gait and other low-and high-demand activities were present in patients with an ACL bone-patellar tendon reconstruction and, if so, whether they were related to strength. More specifically, we examined how the sagittal plane joint angles and external moments during walking, stair-climbing, and jogging activities differed between healthy subjects and patients with a reconstructed ACL and whether those differences related to isokinetic quadriceps and hamstring muscle strength. MATERIALS AND METHODS Twenty-two subjects (mean age, 27 Ϯ 11 years) who underwent an autogenous patellar tendon reconstruction for ACL deficiency were tested and compared with a group of 22 uninjured control subjects. The ACL-reconstructed group consisted of 13 men and 9 women. Patients in the ACL-reconstructed group underwent surgery at an average of 8 months (range, 1 to 24) after injury and were examined at a mean follow-up of 22 Ϯ 12 months. Excluded from the study were those patients who had meniscal damage in which more than 25% of the meniscus was removed, posterior cruciate or collateral ligament injury, articular surface injury, symptomatic anterior knee pain, or objective instability at latest follow-up examination (positive pivot shift test results, positive Lachman † Address correspondence and reprint requests to Charles A. Bush-Joseph, MD, Rush-Presbyterian-St