35 research outputs found

    Podcast, Audacity, Youtube, Skypecast, Chat e Webquest: possibilidades didáctico-pedagógicas na Internet para o docente de língua Inglesa

    Get PDF
    "A pesquisa que se apresenta discute possibilidades formativas da utilização de ambientes virtuais de aprendizagem. Foi embasada num curso de formação continuada com oito professores de Língua Inglesa do ensino superior. Foram propostos, utilizados e avaliados recursos aplicáveis às práticas educativas: Podcast, Audacity, YouTube, Skypecast, Chat e Webquest. A avaliação foi feita com base nas respostas a perguntas e questionários, que foram submetidas à análise de conteúdo. Os resultados mostram que os ambientes virtuais possibilitam novas práticas educativas com ganhos para o ensino-aprendizagem. A análise configurou categorias relacionadas à formação continuada docente, que exprimem as possibilidades didático-pedagógicas do computador e da Internet: objeto, novo, interação, comunicação, mudança, curso, atualização, Internet, resistência à mudança, melhora, equipamento. Palavras-chave: Ambientes virtuais de aprendizagem, docência, formação continuada, Língua Inglesa. --MARSON, Isabel Cristina & SANTOS, Ademir Yaldir (2008). Podcast, Audacity, Youtube, Skypecast, Chat e Webquest: Possibilidades didáctico-pedagógicas na Internet para o docente de língua Inglesa. In <i>Educação, Formação & Tecnologias; </i>vol.1 (2); pp. 40-49, Novembro de 2008; disponível no URL: http://eft.educom.pt.--" &nbsp

    PRONÚNCIA EM LÍNGUA INGLESA: PERCEPÇÃO DOS ALUNOS DE GRADUAÇÃO EM LETRA

    Get PDF
    Este estudo busca verificar a percepção de alunos em formação inicial do curso de Letras sobre aspectos relacionados à pronúncia em língua inglesa. Para coleta dos dados, um questionário contendo dez questões de múltipla escolha foi aplicado a 51 alunos estudantes de diferentes períodos do curso. Os resultados mostraram que o ensino da pronúncia é percebido como importante para a formação do professor e que, embora os alunos consideram que há diferentes variáveis num contexto comunicativo, ainda existe um modelo padrão a ser seguido

    CONCEPÇÕES DE LÍNGUA(GEM) E LEITURA: PRÁTICAS DE PROFESSORES DE LÍNGUA INGLESA EM ATUAÇÃO

    Get PDF
    Partindo do pressuposto que a maneira como o professor entende e reflete sobre língua(gem) interfere diretamente na sua ação pedagógica em sala de aula, pretende-se neste artigo discutir a respeito das concepções de língua(gem) e de práticas de leituras que professores de língua inglesa possuem, e como essas perspectivas intervém nas suas ações pedagógicas. A pesquisa foi realizada com seis professores de língua inglesa pertencentes a três localidades do Paraná: Ponta Grossa, Curitiba e Tomazina. Os dados foram gerados a partir de questionários estruturados e semiestruturados e, posteriormente foram analisados qualitativamente. Os resultados levaram a conclusão de que, apesar dos professores se mostrarem abertos a concepções pós-estruturalistas, e também acreditarem na língua como ideológica, permeada por relações de poder, as suas práticas ainda refletem um ensino estruturalista, o qual pode ser verificado pelo apego ao livro didático, a norma-padrão e o controle da sala de aula

    Effect of exercise test on pulmonary function of obese adolescents

    Get PDF
    AbstractObjectiveto investigate the pulmonary response to exercise of non-morbidly obese adolescents, considering the gender.Methodsa prospective cross-sectional study was conducted with 92 adolescents (47 obese and 45 eutrophic), divided in four groups according to obesity and gender. Anthropometric parameters, pulmonary function (spirometry and oxygen saturation [SatO2]), heart rate (HR), blood pressure (BP), respiratory rate (RR), and respiratory muscle strength were measured. Pulmonary function parameters were measured before, during, and after the exercise test.ResultsBP and HR were higher in obese individuals during the exercise test (p = 0.0001). SatO2 values decreased during exercise in obese adolescents (p = 0.0001). Obese males had higher levels of maximum inspiratory and expiratory pressures (p = 0.0002) when compared to obese and eutrophic females. Obese males showed lower values of maximum voluntary ventilation, forced vital capacity, and forced expiratory volume in the first second when compared to eutrophic males, before and after exercise (p = 0.0005). Obese females had greater inspiratory capacity compared to eutrophic females (p = 0.0001). Expiratory reserve volume was lower in obese subjects when compared to controls (p ≤ 0.05).Conclusionobese adolescents presented changes in pulmonary function at rest and these changes remained present during exercise. The spirometric and cardiorespiratory values were different in the four study groups. The present data demonstrated that, in spite of differences in lung growth, the model of fat distribution alters pulmonary function differently in obese female and male adolescents

    Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions

    Get PDF
    Carbamazepine (CBZ) causes life-threating T-cell-mediated hypersensitivity reactions, including serious cutaneous adverse reactions (SCARs) and drug-induced liver injury (CBZ-DILI). In order to evaluate shared or phenotype-specific genetic predisposing factors for CBZ hypersensitivity reactions, we performed a meta-analysis of two genomewide association studies (GWAS) on a total of 43 well-phenotyped Northern and Southern European CBZ-SCAR cases and 10,701 population controls and a GWAS on 12 CBZ-DILI cases and 8,438 ethnically matched population controls. HLA-A*31:01 was identified as the strongest genetic predisposing factor for both CBZ-SCAR (odds ratio (OR) = 8.0; 95% CI 4.10-15.80; P = 1.2 x 10(-9)) and CBZ-DILI (OR = 7.3; 95% CI 2.47-23.67; P = 0.0004) in European populations. The association with HLA-A*31:01 in patients with SCAR was mainly driven by hypersensitivity syndrome (OR = 12.9; P = 2.1 x 10(-9)) rather than by Stevens-Johnson syndrome/toxic epidermal necrolysis cases, which showed an association with HLA-B*57:01. We also identified a novel risk locus mapping to ALK only for CBZ-SCAR cases, which needs replication in additional cohorts and functional evaluation.Peer reviewe

    IMPACT-Global Hip Fracture Audit: Nosocomial infection, risk prediction and prognostication, minimum reporting standards and global collaborative audit. Lessons from an international multicentre study of 7,090 patients conducted in 14 nations during the COVID-19 pandemic

    Get PDF

    Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Get PDF
    We identified rare coding variants associated with Alzheimer’s disease (AD) in a 3-stage case-control study of 85,133 subjects. In stage 1, 34,174 samples were genotyped using a whole-exome microarray. In stage 2, we tested associated variants (P<1×10-4) in 35,962 independent samples using de novo genotyping and imputed genotypes. In stage 3, an additional 14,997 samples were used to test the most significant stage 2 associations (P<5×10-8) using imputed genotypes. We observed 3 novel genome-wide significant (GWS) AD associated non-synonymous variants; a protective variant in PLCG2 (rs72824905/p.P522R, P=5.38×10-10, OR=0.68, MAFcases=0.0059, MAFcontrols=0.0093), a risk variant in ABI3 (rs616338/p.S209F, P=4.56×10-10, OR=1.43, MAFcases=0.011, MAFcontrols=0.008), and a novel GWS variant in TREM2 (rs143332484/p.R62H, P=1.55×10-14, OR=1.67, MAFcases=0.0143, MAFcontrols=0.0089), a known AD susceptibility gene. These protein-coding changes are in genes highly expressed in microglia and highlight an immune-related protein-protein interaction network enriched for previously identified AD risk genes. These genetic findings provide additional evidence that the microglia-mediated innate immune response contributes directly to AD development

    The genetic architecture of the human cerebral cortex

    Get PDF
    The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder
    corecore