146 research outputs found

    Células-tronco: uma breve revisão

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    Stem cells are non-differential cells or with low differential degree found in both embryonic and extra-embryonic tissues. They may remain in quiescence state until adulthood, through self-replication, or may be different in several tissues, depending on the expression of certain genes. Thus, they may perform specific functions. Many studies have been addressed for the use of those cells in the therapy of several diseases, and the recent results have been quite promising. Many authors believe that the stem cells represent the therapy of the future and that it may provide the cure for some diseases such as diabetes, cardiopathies, cancer and Alzheimer disease.As células-tronco são células indiferenciadas ou com baixo grau de diferenciação, encontradas em tecidos embrionário e extra-embrionário. Podem permanecer em estado quiescente até a fase adulta, através da auto-replicação, ou diferenciar-se em diversos tecidos, a partir da expressão de determinados genes, e exercer funções específicas. Muitos estudos vêm sendo direcionados para a utilização dessas células na terapia de várias doenças, e os resultados obtidos até então são bastante promissores, o que faz muitos autores acreditarem que as células-tronco representam a terapia do futuro, podendo significar a cura de determinadas doenças, tais como diabetes, cardiopatias, câncer e mal de Alzheimer

    Análise temporal e espacial da mortalidade materna por transtornos hipertensivos no ciclo gravídico puerperal no Brasil no período de 2001 a 2020: Temporal and spatial analysis of maternal mortality due to hypertensive disorders in pregnancy-puerperal cycle in Brazil from 2001 to 2020

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    A síndrome hipertensiva gestacional é uma das principais responsáveis pela mortalidade materna em países em desenvolvimento. O Brasil, por ser uma nação com dimensões continentais, possui uma importante disparidade econômica e social dentre as suas cinco regiões. Objetivos: Comparar temporal e espacialmente a mortalidade por transtornos hipertensivos na gravidez, parto e puerpério no Brasil e nas suas cinco regiões. Metodologia: Realizou-se coleta de dados do DATASUS em um período de janeiro de 2001 a dezembro de 2020, sobre mortalidade, edema, proteinúria, hipertensão pré existente, parto, gravidez e puerpério. Foram analisados 7389 casos compreendidos pelas seguintes categorias da Classificação Internacional de Doenças e Problemas Relacionados à Saúde (CID 10) 0-10 a 0-16. No período de 20 anos, registrou-se, no país, 7389 casos que possuem a Síndrome Hipertensiva Gestacional como causa mortis. A região com maior mortalidade foi a região Nordeste. Conclusão: é uma enfermidade prevalente no Brasil, principalmente, na região nordeste.&nbsp

    Search for supersymmetry in events with a photon, a lepton, and missing transverse momentum in pp collisions at root s=8 TeV

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    Search for single production of scalar leptoquarks in proton-proton collisions at root s=8 TeV

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    Correction DOI:10.1103/PhysRevD.95.039906Peer reviewe

    Limits on the Higgs boson lifetime and width from its decay to four charged leptons

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    Search for pair-produced vectorlike B quarks in proton-proton collisions at root s=8 TeV

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    Search for a massive resonance decaying into a Higgs boson and a W or Z boson in hadronic final states in proton-proton collisions at s√=8 TeV

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    A search for a massive resonance decaying into a standard-model-like Higgs boson (H) and a W or Z boson is reported. The analysis is performed on a data sample corresponding to an integrated luminosity of 19.7 fb1^{-1}, collected in proton-proton collisions at a centre-of-mass energy of 8TeV with the CMS detector at the LHC. Signal events, in which the decay products of Higgs, W, or Z bosons at high Lorentz boost are contained within single reconstructed jets, are identified using jet substructure techniques, including the tagging of b hadrons. This is the first search for heavy resonances decaying into HW or HZ resulting in an all-jet final state, as well as the first application of jet substructure techniques to identify H → WW* → 4q decays at high Lorentz boost. No significant signal is observed and limits are set at 95% confidence level on the production cross sections of W` and Z` in a model with mass-degenerate charged and neutral spin-1 resonances. Resonance masses are excluded for W0 in the interval [1.0, 1.6]TeV, for Z` in the intervals [1.0, 1.1] and [1.3, 1.5]TeV, and for mass-degenerate W` and Z` in the interval [1.0, 1.7]TeV

    Search for third-generation scalar leptoquarks in the tτ channel in proton-proton collisions at √s=8 TeV

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    A search for pair production of third-generation scalar leptoquarks decaying to top quark and τ lepton pairs is presented using proton-proton collision data at a center-of-mass energy of s = 8 s√=8 TeV collected with the CMS detector at the LHC and corresponding to an integrated luminosity of 19.7 fb −1 . The search is performed using events that contain an electron or a muon, a hadronically decaying τ lepton, and two or more jets. The observations are found to be consistent with the standard model predictions. Assuming that all leptoquarks decay to a top quark and a τ lepton, the existence of pair produced, charge −1 / 3, third-generation leptoquarks up to a mass of 685 GeV is excluded at 95% confidence level. This result constitutes the first direct limit for leptoquarks decaying into a top quark and a τ lepton, and may also be applied directly to the pair production of bottom squarks decaying predominantly via the R-parity violating coupling λ 333 ′

    Search for W ' -> tb in proton-proton collisions at root s=8 TeV

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