21 research outputs found
From theory to practice in pattern?oriented modelling: identifying and using empirical patterns in predictive models
- Author
- Publication venue
- Wiley
- Publication date
- 12/05/2021
- Field of study
To robustly predict the effects of disturbance and ecosystem changes on species, it is necessary to produce structurally realistic models with high predictive power and flexibility. To ensure that these models reflect the natural conditions necessary for reliable prediction, models must be informed and tested using relevant empirical observations. Pattern?oriented modelling (POM) offers a systematic framework for employing empirical patterns throughout the modelling process and has been coupled with complex systems modelling, such as in agent?based models (ABMs). However, while the production of ABMs has been rising rapidly, the explicit use of POM has not increased. Challenges with identifying patterns and an absence of specific guidelines on how to implement empirical observations may limit the accessibility of POM and lead to the production of models which lack a systematic consideration of reality. This review serves to provide guidance on how to identify and apply patterns following a POM approach in ABMs (POM?ABMs), specifically addressing: where in the ecological hierarchy can we find patterns; what kinds of patterns are useful; how should simulations and observations be compared; and when in the modelling cycle are patterns used? The guidance and examples provided herein are intended to encourage the application of POM and inspire efficient identification and implementation of patterns for both new and experienced modellers alike. Additionally, by generalising patterns found especially useful for POM?ABM development, these guidelines provide practical help for the identification of data gaps and guide the collection of observations useful for the development and verification of predictive models. Improving the accessibility and explicitness of POM could facilitate the production of robust and structurally realistic models in the ecological community, contributing to the advancement of predictive ecology at large
Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Athar
- Abbasy Jibran
- Abbo Olivier
- Abbott Tom
- Abbouch Meryem
- Abd El-Latif Nadia Khalid
- Abd Elkhalek Esraa
- Abd-Elmawla Manar
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A.
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulaziz Mustafa
- Abdulbagi Omar
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboul-Naga Mariam Saad
- Abouzaid Arwa
- Abu Qumbos Amjad
- Abu-toyour Maram
- Abubakr Marwan
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Ali
- Adam Nourhan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O.
- Ademuyiwa Adesoji O.
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adeyeye Ademola
- Adeyeye Ademola
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O.
- Adiyaman Can
- Adu-Aryee Niiarmah
- Afana Samah
- Agalianos Christos
- Agarwal Arnav
- Agarwal Arnav
- Agbedinu Kwabena
- Aglan Amro
- Aguado Suarez Nuria
- Aguilera Maria Lorena
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahlqvist Sandra
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahounou Ernest Yemalin Stephane
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi
- Ajiboye Anthony
- Akoto Elliot
- Akpenyi Onyinye
- Al Amin Shadid
- Al Attar Samaa Mahmoud
- Al Barraw Fayez Elian
- Al Bastawis Fatema
- Al Meligy Amgad
- Al Rafati Ahmad Abdel Razaq
- Al Raouf Eman Abd
- Al Saied Ghiath
- Al Subaie Norah
- Al-Bahrani Ahmed
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-faqawi Maha
- Al-farram Hadeel
- Al-khatib Ahmed
- Al-Marakby Dina
- Al-saqqa Sara
- Al-Saqqa Sara W.
- Al-Slaibi Ibrahim
- Al-taher Taher
- AlaaelDein Shahinaz
- Alada Muslimat
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Albiety Adel
- Alcca Ticona Willy
- Alejos Bermudez Ysabel Esthefany
- Alexander Philip
- Alexander Philip
- Alexandre Challine
- Alghamdi Ahmed
- Alghamdi Mohammed Saleh A.
- Alhady Khaled
- Alhammali Tariq
- Alhassan Basmah
- Alhazmi Wedyan
- Alherz Mohammad
- Ali Ahmed
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Safia
- Ali Syed Abdul Wahhab Eusoffee Wan
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- Ali Wadah
- Alihonou Thierry
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- Aliyu Halima
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- Aliyu Shamsudeen
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- Alkelani Muhammad
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- Alser Osaid H.
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- Altibi Ahmed
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- Zilinskas Justas
- Zilinskiene Reda
- Ziubryte Greta
- Zohair Ahmed
- Zuber Markus
- Zuk Grzegorz
- Zulkifli Athirah
- Zumbuhl Lucius
- Publication venue
- Elsevier
- Publication date
- 01/06/2003
- Field of study
BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London
Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Athar
- Abbasy Jibran
- Abbo Olivier
- Abbott Tom
- Abbouch Meryem
- Abd El-Latif Nadia Khalid
- Abd Elkhalek Esraa
- Abd-Elmawla Manar
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulaziz Mustafa
- Abdulbagi Omar
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R
- Aboul-Naga Mariam Saad
- Abouzaid Arwa
- Abu Qumbos Amjad
- Abu-toyour Maram
- Abubakr Marwan
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Ali
- Adam Nourhan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Ademuyiwa Adesoji O
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adeyeye Ademola
- Adeyeye Ademola
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O
- Adiyaman Can
- Adu-Aryee Niiarmah
- Afana Samah
- Agalianos Christos
- Agarwal Arnav
- Agarwal Arnav
- Agbedinu Kwabena
- Aglan Amro
- Aguado Suarez Nuria
- Aguilera Maria Lorena
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahlqvist Sandra
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahounou Ernest Yemalin Stephane
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi
- Ajiboye Anthony
- Akoto Elliot
- Akpenyi Onyinye
- Al Amin Shadid
- Al Attar Samaa Mahmoud
- Al Barraw Fayez Elian
- Al Bastawis Fatema
- Al Meligy Amgad
- Al Rafati Ahmad Abdel Razaq
- Al Raouf Eman Abd
- Al Saied Ghiath
- Al Subaie Norah
- Al-Bahrani Ahmed
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-faqawi Maha
- Al-farram Hadeel
- Al-khatib Ahmed
- Al-Marakby Dina
- Al-saqqa Sara
- Al-Saqqa Sara W
- Al-Slaibi Ibrahim
- Al-taher Taher
- AlaaelDein Shahinaz
- Alada Muslimat
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Albiety Adel
- Alcca Ticona Willy
- Alejos Bermudez Ysabel Esthefany
- Alexander Philip
- Alexander Philip
- Alexandre Challine
- Alghamdi Ahmed
- Alghamdi Mohammed Saleh A
- Alhady Khaled
- Alhammali Tariq
- Alhassan Basmah
- Alhazmi Wedyan
- Alherz Mohammad
- Ali Ahmed
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Safia
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Ali Wadah
- Alihonou Thierry
- Alis Halil
- Aliyu Halima
- Aliyu Mohammad
- Aliyu Shamsudeen
- Aljboor Khaled
- Aljiffry Murad
- Alkaaki Aroub
- Alkelani Muhammad
- Allam Meran
- Allam Yomna
- Alnaby Mohamed Hassab
- Alnusairat Aseel
- Alqahtani Saleh
- Alsaggaf Mohammed Ubaid
- Alser Osaid H
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
- Altamimi Afnan
- Altamini Afnan
- Altarayra Marwa
- Altibi Ahmed
- Altinel Yuksel
- Altinel Yuksel
- Altwijri Abdulaziz
- Alvi Abdul Rehman
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alzahrani Ahmed
- Aman Nowrin F
- Amandito Radhian
- Amandito Radhian
- Ambrona-Zafra David
- Amin Hager Abdul Aziz
- Amjad Mohammadasim
- Amoah Michael
- Amoako Joachim
- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
- Anderson Frank
- Andika Ferry Fitriya Ayu
- Andreotti Dario
- Andress Cedar
- Andriola Valeria
- Ang Yun Lin
- Angelieri Daniele
- Anis Echaieb
- Ansaloni Luca
- Ansaloni Luca
- Ansaloni Luca
- Antezana Diego
- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Nourhan
- Anyanwu Lofty-John
- Aonzo Paolo
- Appeadu-Mensah William
- Appiah Eric Kofi
- Aquilino Fabrizio
- Arafa Omar
- Arafa Sara
- Arango Maria Clara Mendoza
- Arcudi Claudio
- Armellini Andrea
- Arnaud Alexis
- Arnaud Alexis Pierre
- Arshad Mohammad Mohsin
- Arslan Ekin
- Arsyad Hasbi Maulana
- Arthur Tom
- Aruldas Neerav
- Asar Yomna Hosny
- Asare-Bediako Kwasi
- Ashour Ahmad
- Ashour Ahmad
- Ashour Khlood
- Ashtari Morvarid
- Asi Fatema
- Asilah Siti Mohd Desa
- Assal Abdelrahman
- Asturias Sabrina
- Asumah Hamza
- Ata Ahmed
- Ata Aya Yehia
- Atiyeh Anwar
- Atkins Ebenezer Takyi
- Attia Attia
- Augestad Knut Magne
- Aviles Susan
- Avoka Anthony
- Awad Israa
- Awad Sawsan Adel
- Awadallah Salwa
- Ayandipo Omobolaji
- Aydin Mehmet Can
- Aziz Dayang Nita Abdul
- Aziz Mohamed Rezal Abdul
- Aziz Nora Abdul
- Azizeldine Mohammed G
- Azzie Georges
- Azzis Olivier
- Baba Suleiman
- Bachri Houda
- Badawy Mahmoud
- Badenjki Mohamed Adel
- Badicel Maria
- Badr Mohamed Fawzy Mahrous
- Badwi Nermin Mohamed
- Bahar Suraya
- Baillie Katie
- Baki Bahadir Emre
- Bakr Ahmad
- Bakry Hesham Mohammed
- Bala Miklosh
- Balalis Dimitrios
- Balducci Genoveffa
- Ballouhey Quentin
- Balmaceda Ruben
- Balmaceda Ruben
- Balogun Fatai
- Baltrunas Robertas
- Baluch Fatima
- Bamford Rebecca
- Bamicha Athanasia
- Banaitis Vincas Jonas
- Bandi Ashwath
- Bandoh Dickson
- Bani-Sadar Ahmad
- Banipal Gurpreet Singh
- Baquero Suarez Alibeth Andres
- Baraka Heba
- Barendegere Venerand
- Barkolias Christos
- Barmayehvar Behrad
- Barnabas Gandau Naa
- Barrios Emmanuel
- Basilico Silvia
- Basir Elissa Rifhan Mohd
- Bassem Monica
- Bassit Khalil Abdul
- Basso Stefano MM
- Bayram Sefa
- Beamon Mieshia
- Bedada Alemayehu Ginbo
- BediakoBowan Antoinette
- Bekhet Amira Hassan
- Bekhet Nada Mohamed
- Beleno Alvaro Enrique Mendoza
- Belkouchi Abdelkader
- Belli Andrea
- Bello Bashir
- Benammi Sarah
- Benevento Angelo
- Bennai Redouane Mammar
- Bentounsi Zineb
- Benyaiche Chaymae
- Berti Stefano
- Bertuello Isaac
- Beuran Mircea
- Bhangu Aneel
- Bhangu Aneel
- Bhangu Anna
- Bhatnagar Ankur
- Bhopal Kamran Faisal
- Bianco Federica
- Bigaran Annamaria
- Billy Matthew
- Bin Adnan Ahmad
- Bin Hasnan Muhammad
- Bin Ismail Mohamad Jeffrey
- Birindelli Arianna
- Bisset Carly
- Bjorklund Ida
- Blacker Sarah
- Blackwell James
- Blanco Ruth
- Blanco-Colino Ruth
- Blencowe Natalie
- Bliksoen Marte
- Bluelle Rafael
- Bocchetti Tommaso
- Bode Chris
- Bodur Selim
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- Bonavia Karl
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- Bond-Smith Giles
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- Borg Elaine
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- Bowling Kirk
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- Bratu Matei
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- Breaud Jean
- Breistrand Michaela
- Breslin Ryan
- Brincat Svetlana Doris
- Broch Aline
- Brunoni Beatrice
- Bsisu Isam
- Bucci Luigi
- Buisson Philippe
- Bunting David
- Burger Sule
- Burmistrovas Andrius
- Bustangi Nasir
- Bustangi Nasir
- Butt Muhammad Talha
- Cakaloglu Haluk Cem
- Caliman Celeste
- Callan Rory
- Camilleri Georgette Marie
- Camilleri-Brennan Julian
- Campagnaro Tommaso
- Canta Calua Alexander
- Capito Carmen
- Carabott Kurt
- Carmela Lapitan Marie
- Carmona Juan Manuel
- Carpio Juan
- Carrasco Nahilia
- Cassar Kristina
- Catani Marco
- Cautiero Roberto
- Caydiid Hanaan
- Cecilia Tolg
- Celik Saban
- Cengiz Turgut Bora
- Cengiz Yucel
- Cengiz Yucel
- Cevik Muazzez
- Chabok Abbas
- Chai Chu-Ann
- Chai Feng Yih
- Chan Luke
- Chan Tsz-Yan Katie
- Chan Xue Wei
- Charles Angeline
- Cheah Alvin Ee Zhiun
- Chen Kar Yan
- Chen Tzu-Ling
- Cheong Yih Jeng
- Chetta Nicola
- Cheung Yuk Hong Eric
- Chibuye Chali
- Chiesa Deborah
- Chilton Gareth
- Chin Pui Xin
- Chin Ye Ru
- Chiu Seehui
- Choi Philip
- Chong Choon Seng
- Chong Hoong-Yin
- Choudhry Asad
- Chow Crystal Yern Nee
- Chowdhury Debkumar
- Chu Kathryn
- Chung Kuet Jun
- Chungui Bravo Jorge Armando
- Ciccioli Eleonora
- Ciubotaru Cezar
- Claire Raquillet
- Clarissa Audrey
- Clegg-Lampety Joe-Nat
- Clegg-Lamptey Joe-Nat
- Clerico Giuseppe
- Coccolini Federico
- Coccolini Federico
- Cocorullo Gianfranco
- Cohen Fraser
- Cole Simon
- Coletta Diego
- Coletti Massimo
- Collaborative GlobalSurg
- Cona Camilla
- Conci Simone
- Confalonieri Gianmaria
- Conlon Kevin C
- Connor Katie
- Contreras Elisa
- Coompson Christian Lari
- Corbellini Carlo
- Corbellino Mario
- Cornick Jen
- Coronel Jazmin
- Corral Moreno Sara
- Correa Juan Camilo
- Corro-Diaz Samantha
- Costa Cecilia
- Costa-Maia Jose
- Costas-Chavarri Ainhoa
- Courboin Etienne
- Cox Daniel
- Cox Michael
- Coyoy-Gaitan Otto
- Craus-Miguel Andrea
- Cullen Fraser
- Curletti Gianluca
- Currow Chelise
- D'Amours Scott
- D'Souza Michelle S
- Dabboor Majd
- Dabbour Kareem
- Dagoe Enoch
- Dahy Ahmed
- Dainius Edvinas
- Dakubo Jonathan
- Dalli Jeffrey
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- Dambrauskas Zilvinas
- Daniyan Muhammad
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- Darwish Abdelrhman KZ
- Dasari Mohini
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- Dassah Victor
- Datta Uttaran
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- Davor Anthony
- Dawood Khaled
- Dayie Makafui
- De Boni Davide
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- De Luca Emilia
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- Deal Rebecca
- Deane Chelsea
- Debrah Sam
- Dedekind Britta
- Dedey Florence
- Del Basso Celeste
- del Pilar Paucar Arazzelly
- Delforge Xavier
- Dell Angela
- Denakpo Max
- Denewar Adel
- Depalma Norma
- Der Yishan
- Deutschmann Peter
- Dhillon Dharminder
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- Di Saverio Salomone
- Diaconescu Bogdan
- Diaz Vico Tamara
- Diaz Zorrilla Carmina
- Diaz-Jover Paula
- Dick Lachlan
- Dijan Emilio
- Dimech Thea
- Din Farhat
- Dindyal Shiva
- Dione Parreno-Sacdalan Marie
- Dissanayake Tharindra
- Djivoh Fernande
- Domini Edgar
- Donnelly Philippa
- Dorani Radin Mohd Nurrahman Radin
- Dorisme Asnel
- Dossou Francis
- Dousset Bertrand
- Dragatas Deividas
- Drake Thomas M
- Drake Thomas M
- Drungilas Mantas
- du Plooy Flip
- Du Toit Frederick
- Duane Therese
- Duinhouwer Lucia
- Dulskas Audrius
- Ebidy Mai
- Ebidy Mai Mohamed
- Eid Mostafa Mahmoud
- El Dahab Ali Abo
- El Gendy Noran Halim
- El Halawany Mohamed
- El Jamassi Alaa
- El Kashash Ahmed
- El Sayed Islam Magdy
- El-Dien Khalid Salah
- El-Din Reham Alaa
- El-Din Shahinaz Alaa
- El-Gizawy Esraa
- El-Sagheer Nada
- El-Sawy Aya
- El-Sehily Ahmed
- El-Taher Esraa
- Elashry Rehab
- Elazab Alaa
- Elbanby Esraa Samir
- Elbe Peter
- Elbisomy Khaled Hesham
- Eldafrawy Mahmoud
- Eldeeb Ahmed Zaki
- Eldeen Esraa Alm
- Eldin Mostafa Ahmed Bahaa
- Elebute Olumide
- Elfarargy Arwa
- Elfeki Hossam
- Elfiky Mahmoud
- Elfouly Nesma
- Elfouly Yasmin
- Elgendy Alyaa Halim
- Elgheriany Mohammed
- Elhadad Alaa
- Elhadary Nourhan Medhat
- Elhadry Shady
- Elhalawany Esraa
- Elhamouly Sara
- Elhelbawy Mohamed Salah
- Elhendawy Abdelaziz
- Elhoseny Ghada
- Elhusseiny Ahmed Abd Elmoen
- Elkholy Shimaa Said
- Ellison Quinn
- Elmashala Amjad
- Elmasry Maha
- Elmihy Sohaila
- Elnagar Ahmedglal
- Elnajjar Mahmoud A
- Elrazek Aly Abd
- Elsabbagh Nourhan
- Elsameea Ahmed Abd
- Elsawy Amira
- Elsayed Nada Ahmed Reda
- Elsemelawy Rofida
- Elshaar Mohammed
- Elshaer Mohamed
- Elshami Mohamedraed
- Elsharkawy Aya Adel
- Elsherbiney Saged
- Elsherif Fawzia Abdellatif
- Elwy Eman
- Elzahed Nada
- Emadeldin Hossam
- Emara Eman
- Emile Sameh
- Eng Calvin
- English William
- Esam Abeer
- Escalante Salas Marilia Del Carmen
- Espin-Basany Eloy
- Espinoza Fernando
- Essam AA
- Essam Ahmed
- Essam Mahitab
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- Estee Mahnuma Mahfuz
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- Etienne Sara
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- Evans Elizabeth
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- Falaschi Federica
- Falco Nicolo
- Falzon Malcolm
- Farag Ahmed
- Farag Sameh
- Farahat Mahitab Morsy
- Fares Mohamed
- Farhan-Alanie Muhamed MH
- Farhangmehr Neda
- Farouk Sara Amr Mohamed
- Farrugia Alexia
- Farrugia Alexia
- Faruq Amreen
- Fathy Aya Mohamed
- Fatuga Adedeji
- Faturoti Olubukola
- Favero Alessandro
- Feidantsis Thomas
- Fergany Alaa
- Fergusson Stuart J
- Fergusson Stuart J
- Fermani Claudio Gabriel
- Fernandes Cristina
- Fernandez Carmen
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- Ferousis Christoforos
- Ferrero Esther
- Filatau Aliaksandr
- Firdouse Mohammed
- Firdouse Mohammed
- Firwana Aya
- Fitsum Agazi
- Fitzgerald J Edward
- Fitzgerald J Edward
- Florez Farfan Erick Samuel
- Foco Maurizio
- Fok Chi Ying Jacquelyn
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- Fuentes-Rivera Lorena
- Gaafar Shireen
- Gaarder Tina
- Gad Ahmed
- Gad Mariam O
- Gadelkarim Mohamed
- Gado Ammar
- Gaizauskas Vytautas
- Gala Tanzeela
- Gala Tanzeela
- Galiqi Gezim
- Galleano Raffaele
- Gallo Gaetano
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- Gribauskaite Jolanta
- Griffiths Ewen
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- Grizhja Besmir
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- Grosos Celine
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- Gudal Ahmad
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- Guevara Torres Shalon
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- Gul Enisburak
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- Gulcicek Osman Bilgin
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- Gyedu Adam
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- Haffreingue Aurore
- Hagan Richmond
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- Halhouli Oday
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- Hamasaki Hamaguchi Jose Luis
- Hamdan Ayah
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- Hamill Daniel
- Hammad Aya
- Hampton Mark Ian
- Hamsho Ward
- Hanoun Sakhaa
- Hantour Usama
- Hany Ethar
- Haque Muhtarima
- Har Prisca AL
- Haraux Elodie
- Harrison Ewen M
- Harrison Ewen M
- Harrison Ewen M
- Hartford Leila
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- Hasan Ahmad
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- Hasanain Doaa
- Hascoet Juliette
- Hashad Eman
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- Haslegrave Aidan
- Hassaan Amr
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- Hassan Ihab
- Hassan Osama Mokhtar Mohamed
- Hassanain Mazen
- Hassanein Adel B
- Heard Rachel
- Hegazy Eman Magdy
- Helene Francois-Coridon
- Helguero-Santin Luis M
- Hemmila Mark
- Heng Hian Ee
- Henric Nicolas
- Henry Fitjerald
- Henshall David Ewart
- Herebat Azher
- Herikstad Ragnar
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- Hmila Sophian
- Ho Adrienne
- Hodonou Fred
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- Homeida Anmar
- Hossameldin Amr
- Hrora Abdelmalek
- Hunter Kristina
- Husseiny Reem
- Iacono Calogero
- Iannone Immacolata
- Ibraheem Aya AbdelFatah
- Ibrahem Ahmad Aboelkassem
- Ibrahim Ahmed Mohamed
- Ibrahim Amal
- Ibrahim Arij
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- Ibrahim Eman
- Ibrahim Eman Mohamed
- Ibrahim Khaled
- Ibrahim Mohamed
- Idress Tasneem
- Idris Faisal
- Iftekhar Farhana
- Iftikhar Zainab
- Ignatavicius Povilas
- Ihediwa George
- Imoro Osman
- Ingabire JC Allen
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- Wong Chui Yee
- Wong Francisca
- Wong Hong Yee
- Wood Greta
- Worku Mengistu
- Worku Tewodros
- Wright Naomi
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yap Suhhuey
- Yau Jih Dar
- Ye Joselyn
- Yeang Li Jing
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yildirim Reyyan
- Yip Chingwan
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yolcu Sinem
- Yong Guo Liang
- Younis Abobaker
- Youssef Mohamed
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zeta Solis Ludwing Alexander
- Zielinski Martin
- Zilinskas Justas
- Zilinskas Justas
- Zilinskas Justas
- Zilinskiene Reda
- Ziubryte Greta
- Zohair Ahmed
- Zuber Markus
- Zuk Grzegorz
- Zulkifli Athirah
- Zumbuhl Lucius
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world.
Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231.
Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001).
Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication
“Finally, we get to play the doctor”: feminist female fans’ reactions to the first female Doctor Who
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- Ang Ien.
- Aronson Jodi.
- Bacon-Smith Camille.
- Booth Paul
- Bowman Cole.
- Boyatzis Richard E.
- Busse Kristina.
- Charles Alec.
- Cherry Brigid.
- Connell Raewyn W.
- De Beauvoir Simone.
- Gray Jonathan
- Hills Matt.
- Hollows Joanne.
- hooks bell.
- Jenkins Henry.
- Jenkins Henry.
- Jenkins Henry.
- Kligler-Vilenchik Neta.
- Larsen Katherine
- Lemish Dafna.
- Levy Ariel.
- Linden Henrik
- Lorde Audre.
- Maynard Mary.
- McMurtry Leslie.
- McRobbie Angela.
- Nicholls Emily.
- Pande Rukmini.
- Penny Laurie.
- Proctor William
- Radway Janice A.
- Reinhard CarrieLynn D.
- Sandvoss Cornell.
- Tagg John.
- Thomas Lynn M.
- Thornton Sarah.
- Tulloch John
- Tulloch John
- Wallace Richard.
- Williams Rebecca
- Winstead Antoinette F.
- Wolf Naomi.
- Wood Mara.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
The potential impact of antiretroviral therapy on fertility in sub-Saharan Africa
- Author
- A Desgrees-du-Lou
- A Desgrees-du-Lou
- A Pebley
- A Ross
- A Suy
- AJ Gage
- Angela Kaida
- B Zaba
- BH Benthem van
- BW Forsyth
- C Baylies
- C D‘Ubaldo
- C Hankins
- C Seyler
- C Thorne
- Centers for Disease Control and Prevention
- David R. Bangsberg
- ER Fapohunda
- FJ Palella Jr
- Francisco I. Bastos
- G Asiimwe-Okiror
- G Sedgh
- Glenda Gray
- GP Garnett
- I Vincenzi De
- Irene Andia
- J Bongaarts
- J Mukiza-Gapere
- J Stover
- JC Okeibunor
- Jerry Spiegel
- JG Cleland
- JJ Lewis
- JM Blair
- JN Krieger
- Joint United Nations Programme on HIV/AIDS
- JP Moatti
- JPM Ntozi
- JR Glynn
- JT Boerma
- K Wools-Kaloustian
- KD Chirgwin
- L Panozzo
- L Porter
- LM Lee
- LS Massad
- M Carael
- M Fabiani
- M Garenne
- M Temmerman
- MA Loko
- Marissa Maier
- MJ Wawer
- N Rutenberg
- N Terceira
- OP Arya
- P Brocklehurst
- P Gaillard
- P Mayaud
- PM Martin
- R Widy-Wirski
- RE Tuomala
- RE Tuomala
- RH Gray
- Robert Hogg
- RS Hogg
- S Allen
- S Becker
- S Gregson
- S Gregson
- Steffanie A. Strathdee
- SV Thackway
- T Lutalo
- U Larsen
- U Larsen
- V Leroy
- World Health Organization
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Surgical site infection after gastrointestinal surgery in children : an international, multicentre, prospective cohort study
- Author
- A A Essam
- A B Jayathilake
- Abbas Chabok
- Abd Elkhalek Sallam
- Abdalla Gamal Saad
- Abdelaziz Abdelaal
- Abdelaziz Elhendawy
- Abdelkader Belkouchi
- Abdelmalek Hrora
- Abdelrahman Adelshone
- Abdelrahman Assal
- Abdelrahman Geuoshy
- Abdelrahman Soliman
- Abdelrhman Kz Darwish
- Abdul Rehman Alvi
- Abdulaziz Altwijri
- Abdullah Altamimi
- Abdullah Hashim
- Abdulmalik Altaf
- Abdulrahman Abdel-Aty
- Abdulrasheed Nasir
- Abdulrazzaq Lawal
- Abdulshafi Khaled AbdRabou
- Abdurrahaman Sheshe
- Abdussemiu Abdurrazzaaq
- Abeer Esam
- Abhishek Sharma
- Abiboye Yifieyeh
- Abobaker Younis
- Abrar Nawawi
- Adam Boggon
- Adam Gyedu
- Ade Waterman
- Adedapo Osinowo
- Adedeji Fatuga
- Adel Albiety
- Adel B Hassanein
- Adel Denewer
- Ademola Adebanjo
- Ademola Adeyeye
- Ademola Popoola
- Adesina Adedeji
- Adesoji O Ademuyiwa
- Adewale Adeniyi
- Adewale O Adisa
- Adham Tarek
- Adomas Ladukas
- Adrian Palma
- Adrienne Ho
- Afifatun Hasanah
- Afizah Salleh
- Afnan Abdelfatah
- Afnan Altamimi
- Afnan Altamini
- Agazi Fitsum
- Agboola Taiwo
- Ahed Ghaben
- Ahmad Abdel Razaq Al Rafati
- Ahmad Aboelkassem Ibrahem
- Ahmad Ashour
- Ahmad Ashour
- Ahmad Bakr
- Ahmad Bani-Sadar
- Ahmad Bin Adnan
- Ahmad Gudal
- Ahmad Hasan
- Ahmad Khaled Sabe
- Ahmad Khoja
- Ahmad Qaissieh
- Ahmad Sabe
- Ahmad Saber Sleem
- Ahmad Sakr
- Ahmad Shalabi
- Ahmad Uzair Qureshi
- Ahmed Aamer
- Ahmed Abd El-Sameea
- Ahmed Abd Elmoen Elhusseiny
- Ahmed Adamu
- Ahmed Al-Bahrani
- Ahmed Alghamdi
- Ahmed Ali
- Ahmed Alkhatib
- Ahmed Altibi
- Ahmed Alzahrani
- Ahmed Ata
- Ahmed Dahy
- Ahmed El Kashash
- Ahmed El-Sehily
- Ahmed Essam
- Ahmed Farag
- Ahmed Gad
- Ahmed Ghanem
- Ahmed Hossam Eldin Fouad Rida
- Ahmed Ismail
- Ahmed M Rashed
- Ahmed Magdy
- Ahmed Mahmoud Abdelraouf
- Ahmed Mohamed Ibrahim
- Ahmed Moustafa
- Ahmed Rabeih Mohammed
- Ahmed Rabie Mohamed
- Ahmed Raza
- Ahmed Said Badr
- Ahmed Shahine
- Ahmed Sheta
- Ahmed Soliman
- Ahmed Tarek Abdelbaset Hassan
- Ahmed W Shamsedine
- Ahmed Zaki
- Ahmed Zaki Eldeeb
- Ahmed Zohair
- Ahmedali M Kandil
- Ahmedglal Elnagar
- Ahmet Murat Pektaş
- Aia Mehdi
- Aida Suarez
- Aidan Haslegrave
- Ainhoa Costas-Chavarri
- Aized Raza Shahbaz
- Akin Olaolorun
- Akinlabi Ajao
- Al Faifi Jubran
- Ala Shamasneh
- Alaa Al-Buhaisi
- Alaa Bowabsak
- Alaa El Jamassi
- Alaa Elazab
- Alaa Elhadad
- Alaa Fergany
- Alaa Shaheen
- Alaba Adesina
- Alberto Miyar de León
- Alberto Realis Luc
- Alejandro Matheu
- Alemayehu Ginbo Bedada
- Alessandro Favero
- Alex Makupe
- Alex Reece-Smith
- Alexander Canta Calua
- Alexander Smedley
- Alexandra Gerosa
- Alexia Farrugia
- Alexis Arnaud
- Alexis Pierre Arnaud
- Alfio Alessandro Russo
- Alfredo Gulielmi
- Ali Ababneh
- Ali Abo El Dahab
- Ali Adam
- Ali Guner
- Ali Khan Niazi
- Ali Mussad
- Aliaksandr Filatau
- Aliang Latif
- Alibeth Andres Baquero Suarez
- Alice Murray
- Alina Robledo-Rabanal
- Aline Broch
- Alissa Gübeli
- Alistair Rocke
- Aliyu Ndajiwo
- Alphonse Zeta Mutabazi
- Alvaro Enrique Mendoza Beleño
- Alvin Ee Zhiun Cheah
- Aly Abd-Elrazek
- Aly Sanad
- Alyaa Halim Elgendy
- Amal Ibrahim
- Amany Eldosouky Mohammed
- Amar Kourdouli
- Amgad Al Meligy
- Amina Abdelhamid
- Aminah Hanum Haji Abdul Majid
- Aminu Mohammad
- Amir Ait Kaci
- Amira Elsawy
- Amira Hassan Bekhet
- Amira Reda
- Amjad Abu Qumbos
- Amjad Elmashala
- Ammar Gado
- Amna Mamdouh Mohamed
- Amna Mohamed
- Amr Ahmed Saleh
- Amr Hassaan
- Amr Hossameldin
- Amreen Faruq
- Amro Aglan
- Ana Lucia Contreras-Vergara
- Ana Maria Sandoval Barrantes
- Anahita Mansuri
- Anan Rady Abdelazeam
- Anass Majbar
- Anastasios Stefanopoulos
- Anders Thorell
- Andre L Mihaljevic
- Andre Navarro
- Andrea Armellini
- Andrea Belli
- Andrea Bondurri
- Andrea Craus-Miguel
- Andrea Natili
- Andrea Ruzzenente
- Andrea Simioni
- Andreass Haloho
- Andrejus Subocius
- Andrew Kirby
- Andrey Litvin
- Andrius Burmistrovas
- Angel David Pérez Rojas
- Angela Dell
- Angela Mazzella
- Angelica Genoveva Vergara Mejia
- Angeline Charles
- Angelo Antoniozzi
- Angelo Benevento
- Angelos Tselos
- Anil Kaul
- Anil Semiz
- Ankur Bhatnagar
- Anmar Homeida
- Anna Jeffery
- Anna Lasek
- Anna Maffioli
- Anna Rinaldi
- Anna Verbeek
- Annalisa Lo Conte
- Annamaria Bigaran
- Annisa Dewi Fitriana Mukin
- Antanas Gulbinas
- Antanas Zadoroznas
- Anthonius Santoso Rulie
- Anthony Ajiboye
- Anthony Avoka
- Anthony Chuk-Him Lai
- Anthony Davor
- Anthony Sander
- Antoinette Bediako-Bowan
- Antonella La Brocca
- Antonio Nocito
- Antonio Picardo
- Antonio Ramos-De la Medina
- Antonio Taddei
- Anwar Atiyeh
- Anyomih Theophilus Teddy Kojo
- April Camilla Roslani
- Aram Abdelhaq
- Arazzelly Del Pilar Paucar
- Arcangelo Picciariello
- Arestis Sokratous
- Arezo Kanani
- Ari Leppäniemi
- Ariadne L'Heveder
- Arianna Birindelli
- Arij Ibrahim
- Arjun Paramasivan
- Arlindawati Suyadi
- Armando José Román Velásquez
- Arnav Agarwal
- Aroub Alkaaki
- Arturas Vaicius
- Arvin Khamajeet
- Arvo Reinsoo
- Arwa Abouzaid
- Arwa Elfarargy
- Arwa Ibrahim
- Arwa Mohamed
- Asad Choudhry
- Asaf Kedar
- Asdaq Ahmed
- Aseel Alnusairat
- Aseel Hamarshi
- Aseel Musleh
- Ashish Gupta
- Ashish Minocha
- Ashraf Maghrabi
- Ashrafun Nessa
- Ashrarur Rahman Mitul
- Ashwath Bandi
- Asmaa Rezq
- Asmaa Salah
- Asnel Dorismé
- Aspasia Papailia
- Astrid Leusink
- Ataa Ahmed
- Athanasia Bamicha
- Athar Abbas
- Athirah Zulkifli
- Athula Tennakoon
- Attia Attia
- Audrey Clarissa
- Audrius Dulskas
- Audrius Parseliunas
- Augusto Zani
- Aurel Mironescu
- Aurel Sandu Mironescu
- Aurelien Scalabre
- Aurora Mariani
- Aurore Haffreingue
- Aurore Thollot
- Awais Raza
- Aya Abdelfatah Ibraheem
- Aya Adel Elsharkawy
- Aya El-Sawy
- Aya Firwana
- Aya Hammad
- Aya Mohamed Fathy
- Aya Reda
- Aya Yehia Ata
- Ayah Hamdan
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- Ayman And Taher
- Ayman Salman
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- Azher Herebat
- Babajide Adenekan
- Babatunde Odeyemi
- Badr Eldin Adel
- Badreldin Adel Tawfik
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- Bahar Busra Ozkan
- Bakeer Mohamed
- Basant Kumar
- Bashir Bello
- Basma Mahmoud
- Basmah Alhassan
- Bassant Mowafy
- Beatrice Brunoni
- Behrad Barmayehvar
- Belen Sanchez
- Benogreît Parmentier
- Berk Baris Ozmen
- Berna Buse Kobal
- Bernard Limoges
- Bernhard Wolf
- Bertrand Dousset
- Besmir Grizhja
- Bettina Lieske
- Betty Maillot
- Bogdan Diaconescu
- Britta Dedekind
- Bruno Noukpozounkou
- Busra Murutoglu
- Bárbara Málaga
- Calogero Iacono
- Calvin Eng
- Cameron Fairfield
- Camila Sanchez Samaniego
- Camilla Cona
- Can Adiyaman
- Carla Soldevila-Verdeguer
- Carlo Corbellini
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- Carly Bisset
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- Caroluce K Musyoka
- Catherine A Shaw
- Catrin Jones
- Catrin Morgan
- Cecile Muller
- Cecilia Costa
- Cedar Andress
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- Celeste Del Basso
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- Cesar Razuri
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- Cheewei Gan
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- Chi Chung Foo
- Chi Ying Jacquelyn Fok
- Chia Kong
- Chimwemwe Kwatiwani
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- Christopher Owen
- Christopher Smith
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- Chu-Ann Chai
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- Cicilia Viany Evajelista
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- Claire Sharpin
- Clare Skerritt
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- Claudio Arcudi
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- Clement Onuoha
- Colombani Jean-Francois
- Cornelius Mukuzunga
- Corrado Bottini
- Cristina Fernandes
- Cristina Pineño-Flores
- Crystal Yern Nee Chow
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- D C Grobler
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- Daniel Hamill
- Daniela Magri
- Daniele Angelieri
- Daniele Gui
- Danilo Herrera Cruz
- Danjuma Sale
- Dansou Gaspard Gbessi
- Dario Andreotti
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- David Bunting
- David Evans
- David Ewart Henshall
- David Merlini
- David Monterroso Cohen
- Davide De Boni
- Davide Rossi
- Dayang Nita Abdul Aziz
- Dayson Kumwenda
- Debkumar Chowdhury
- Deborah Chiesa
- Deborah Saraste
- Deimante Mikuckyte
- Deividas Dragatas
- Demi Gray
- Deniz Mutlu
- Dennis Oswald
- Dharminder Dhillon
- Diaaaldin Zahran
- Diana Sanchez
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- Diego Coletta
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- Diego Sasia
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- Dima Nassif
- Dimitri Aristotle Raptis
- Dimitrios Balalis
- Dimitrios K Manatakis
- Dimitrios Korkolis
- Dimitrios Kyziridis
- Dimitrios Lytras
- Dimitrios Papageorgiou
- Dimitrios Sfougaris
- Dina Al-Marakby
- Dina Faizatur Rahmah
- Dina Fouad
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- Dina Tarek
- Dion Morton
- Djifid Morel Seto
- Dmitri Nepogodiev
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- Doaa Hasan
- Doaa Hasanain
- Doaa Maher Abdelrouf
- Domenica Pata
- Dominic Townsend
- Donal B O'Connor
- Donatas Danys
- Donatas Venskutonis
- Dorota Radkowiak
- Dorothy Kufeji
- Dovilè Majauskyté
- Durvesh Lacthman Jethwani
- Dush Iyer
- Dushyant Iyer
- Dzianis Khokha
- Dzmitry Paulouski
- Ebenezer Takyi Atkins
- Echaieb Anis
- Edgar Domini
- Edvard Grisin
- Edvinas Dainius
- Eimear Monaghan
- Eirik Kjus Aahlin
- Ekin Arslan
- Ekow Mensah
- Elaine Borg
- Elena Goldin
- Elena Muzio
- Elena Vendramin
- Elena Zdanyte Sruogiene
- Eleonora Ciccioli
- Eliana Kalakouti
- Elio Jovine
- Elisa Contreras
- Elisa Francone
- Elisabeth Hall
- Elisabeth Jensen
- Elissa Rifhan Mohd Basir
- Elizabeth Evans
- Elke Reunis
- Ella Teasdale
- Elliot Akoto
- Elodie Haraux
- Eloy Espin-Basany
- Elsa Robert
- Elsayed Ali
- Emad Abdallah
- Emad Al-Dakka
- Eman Abd Al Raouf
- Eman Abdelmageed
- Eman Abuqwaider
- Eman Elwy
- Eman Emara
- Eman Hashad
- Eman Ibrahim
- Eman Magdy
- Eman Magdy Hegazy
- Eman Mahmoud Abdulhakeem
- Eman Mohamed Ibrahim
- Eman Mohamed Morshedy
- Eman Rashad
- Eman Yahya Mansor
- Emeka Nwabuoku
- Emilia de Luca
- Emilio Dijan
- Emin Kose
- Emmanuel Acquah
- Emmanuel Akatibo
- Emmanuel Barrios
- Enas Alaloul
- Enisburak Gül
- Enkhbat Dashnyam
- Enoch Dagoe
- Enoch Tackie
- Enrique Esteban
- Eric Ackom
- Eric Etchill
- Eric Kofi Appiah
- Erick Samuel Florez Farfan
- Erik Hervieux
- Erik Schadde
- Erika Vicario
- Erikas Laugzemys
- Ernest Yemalin Stephane Ahounou
- Eslam Ezzat
- Esraa Abd Elkhalek
- Esraa Abdalmageed Kasem
- Esraa Alm Eldeen
- Esraa El Halawany
- Esraa El-Gizawy
- Esraa El-Taher
- Esraa Gamal
- Esraa Samir Elbanby
- Esraay Zakaria
- Esther Ferrero
- Esther Hg Park
- Ethar Hany
- Etienne Courboin
- Eu Xian Lee
- Eugenio Morandi
- Eunice Zuling Ter
- Evangelos Voulgaris
- Evelina Slapelyte
- Ewen Griffiths
- Ewen M Harrison
- Eyad Khalifah
- Fabrizio Aquilino
- Fahd Abdel Sabour
- Faisal Idris
- Faith Qi Hui Leong
- Fanjandrainy Rasoaherinomenjanahary
- Farah Mahmoud Ali
- Farhana Iftekhar
- Farhat Din
- Farrag Sayed
- Fatai Balogun
- Fatema Al Bastawis
- Fatema Asi
- Fathy Sroor
- Fatima Baluch
- Fatima Sena-Ruiz
- Faustin Ntirenganya
- Fawzia Abdellatif Elsherif
- Fawzy Mohamed
- Fayez Elian Al Barrawi
- Fazlin Noor
- Federica Bianco
- Federica Falaschi
- Federico Coccolini
- Felipe Zapata
- Felix Alakaloko
- Felix Lee
- Feng Yih Chai
- Ferdy Iskandar
- Fernande Djivoh
- Fernando Espinoza
- Ferry Fitriya Ayu Andika
- Fidelis Jacklyn Adella
- Finaritra Casimir Fleur Prudence Rahantasoa
- Fitjerald Henry
- Flip du Plooy
- Florence Dedey
- Francesca Steccanella
- Francesco Pata
- Francesco Riente
- Francesco Ruben Giardino
- Francesco Selvaggi
- Francis Abantanga
- Francis Dossou
- Francisca Wong
- Francois-Coridon Helene
- Frank Anderson
- Frank Enoch Gyamfi
- Frank Owusu
- Françoise Schmitt
- Fraser Cohen
- Fraser Cullen
- Fred Hodonou
- Frederick Du Toit
- Frederick Stourton
- Fredrik Wogensen
- Fridiz Saravia
- Gabriel Pardo
- Gabriela Elisa Nita
- Gabriela Werder
- Gaetano Gallo
- Gaetano Luglio
- Galaleldin Abdelazim
- Gandau Naa Barnabas
- Garba Samson
- Gareth Chilton
- Gareth Irwin
- Gehad Tawfik
- Genoveffa Balducci
- George Christian Manrique Sila
- George Ihediwa
- Georges Azzie
- Georgette Marie Camilleri
- Georgios Gemenetzis
- Georgios Gkiokas
- Georgios Karabelias
- Georgios Kyrou
- Georgios Peros
- Georgios Tzikos
- Gerardo Perrotta
- Germain Ahlonsou
- Gezim Galiqi
- Ghada Elhoseny
- Ghada Saied Nagy
- Ghiath Al Saied
- Giacomo Pata
- Gianfranco Cocorullo
- Gianluca Curletti
- Gianluca Pagano
- Gianluca Pellino
- Gianmaria Confalonieri
- Gianpiero Gravante
- Giedrius Lauzikas
- Giles Bond-Smith
- Gintaras Simutis
- Giorgio Vasquez
- Giovanni Landolfo
- Giovanni Lazzari
- Giovanni Pascale
- Giovanni Pesenti
- Giuliano Borda-Luque
- Giuseppe Clerico
- Giuseppe Rotunno
- Giuseppe Salamone
- Giuseppe Sammarco
- GlobalSurg Collaborative: Aneel Bhangu
- Greg Padmore
- Gregorio Tugnoli
- Greta Wood
- Greta Žiubrytė
- Grzegorz Zuk
- Guillaume Podevin
- Guillermo Sanchez Rosenberg
- Guled M Jama
- Guo Liang Yong
- Gurpreet Singh Banipal
- Gustavo Miguel Machain Vega
- Gustavo Recinos
- Gustavo Rodolfo Pertersen Servin
- Haaris A Shiwani
- Hadeel Al-Farram
- Hager Abdul Aziz Amin
- Hager Abdulaziz
- Haidar Hajeh
- Hakeem Ayomi Sanni
- Hala Saad
- Halil Alis
- Halima Aliyu
- Haluk Cem Çakaloğlu
- Hamza Asumah
- Hanaan Caydiid
- Hanan Adel Saad
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- Thomas Pinkney
- Thomas Prudhomme
- Thomas Tetens Moe
- Tien Seng Bryan Lee
- Tina Gaarder
- Tobias Schuetz
- Todisoa Emmanuella Christina Tolotra
- Tolg Cecilia
- Tom Abbott
- Tom Arthur
- Tomas Abaliksta
- Tomas Jankus
- Tomas Poskus
- Tomas Poškus
- Tomas Urbonas
- Tommaso Bocchetti
- Tommaso Campagnaro
- Tommaso Fontana
- Toqa Khafagy
- Torhild Veen
- Tsz-Yan Katie Chan
- Tuan Nur'Azmah Tuan Mat
- Tunde Sholadoye
- Turgut Bora Cengiz
- Twc Mak
- Tyler Rouse
- Tzu-Ling Chen
- Uday Muddebihal
- Umar Muktar
- Umberto Tedeschi
- Umme Salma
- Usama Hantour
- Uttaran Datta
- Vahit Mutlu
- Valdemaras Jotautas
- Valeria Andriola
- Vanessa Msosa
- Vania Guglielmo
- Vania Silvestri
- Vasileios Kalles
- Vasiliki Soulou
- Vassilis Kalles
- Vedatcan Işler
- Veeranna Shatkar
- Venerand Barendegere
- Veronica Lazzari
- Vicky Jennings
- Victor Dassah
- Victor Etwire
- Victor Kong
- Victor Nwinee
- Vijaid Upadhyaya
- Viktorija Nevieraite
- Ville Sallinen
- Vincas Jonas Banaitis
- Virginia Jiménez Carneros
- Virginia Ramos Pérez
- Viviana Sollazzo
- Vladimir Khokha
- Volkan Ozben
- Vu Thanh Hien Le
- Vytautas Gaižauskas
- Vytautas Lipnickas
- Wadah Ali
- Wai Cheong Soon
- Wai Him Lam
- Wairimu Ndegwa
- Waleed Thabet
- Walter Ruiz Panez
- Wan Nurul 'Ain Wan Mohd Nasir
- Ward Hamsho
- Wasim Dar
- Wedyan Alhazmi
- Weihei Dao
- Wennweoi Goh
- Wifanto Saditya Jeo
- Wiktor Rutkowski
- William Appeadu-Mensah
- William Bonney
- William English
- Willy Alcca Ticona
- Xavier Delforge
- Xianelle Rodriguez
- Xinwei Low
- Xue Wei Chan
- Ya Theng Neo
- Yacoubou Imorou Souaibou
- Yahaya Ukwenya
- Yahya Salama
- Yasmin Elfouly
- Yasmin Soliman
- Ye Ru Chin
- Yee Wen Tan
- Yehia Zakaria
- Yi Koon Tan
- Yi Ting Mok
- Yih Jeng Cheong
- Yiing Yee Gan
- Yishan Der
- Yomna Allam
- Yomna Hosny Asar
- Yong Yong Tew
- Yoshan Moodley
- Yousef Abuowda
- Ysabel Esthefany Alejos Bermúdez
- Yucel Cengiz
- Yuk Hong Eric Cheung
- Yuksel Altinel
- Yun Lin Ang
- Yung Kok Ng
- Yuri Macchitella
- Zahra Jaffry
- Zain Ali Khan
- Zainab Iftikhar
- Zakaria Rob
- Zhan Herr Ng
- Zi Hao Sam
- Zigmantas Urniežius
- Zilvinas Dambrauskas
- Zineb Bentounsi
- Zygimantas Tverskis
- Ömer Faruk Toto
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Introduction Surgical site infection (SSI) is one of the most common healthcare-associated infections (HAIs). However, there is a lack of data available about SSI in children worldwide, especially from low-income and middle-income countries. This study aimed to estimate the incidence of SSI in children and associations between SSI and morbidity across human development settings. Methods A multicentre, international, prospective, validated cohort study of children aged under 16 years undergoing clean-contaminated, contaminated or dirty gastrointestinal surgery. Any hospital in the world providing paediatric surgery was eligible to contribute data between January and July 2016. The primary outcome was the incidence of SSI by 30 days. Relationships between explanatory variables and SSI were examined using multilevel logistic regression. Countries were stratified into high development, middle development and low development groups using the United Nations Human Development Index (HDI). Results Of 1159 children across 181 hospitals in 51 countries, 523 (45 center dot 1%) children were from high HDI, 397 (34 center dot 2%) from middle HDI and 239 (20 center dot 6%) from low HDI countries. The 30-day SSI rate was 6.3% (33/523) in high HDI, 12 center dot 8% (51/397) in middle HDI and 24 center dot 7% (59/239) in low HDI countries. SSI was associated with higher incidence of 30-day mortality, intervention, organ-space infection and other HAIs, with the highest rates seen in low HDI countries. Median length of stay in patients who had an SSI was longer (7.0 days), compared with 3.0 days in patients who did not have an SSI. Use of laparoscopy was associated with significantly lower SSI rates, even after accounting for HDI. Conclusion The odds of SSI in children is nearly four times greater in low HDI compared with high HDI countries. Policies to reduce SSI should be prioritised as part of the wider global agenda.Peer reviewe
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- Accardi Evan
- ACTIV-3/Therapeutics for Inpatients with COVID-19 (TICO) Study Group
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- Aston Valerie T
- Audette Matthew
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- Badhwar Vinay
- Badrock Jonathan
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- Bagiella Emilia
- Baio Kim T
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- Baker Rebecca
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- Baracco Gio
- Baracz Michelle
- Barkauskas Christina E
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- Bayoumi Emad
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- Becker Nancy
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- Bedoya Gabriela
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- Bettacchi Christopher
- Beutler Rebecca
- Bielica Mona
- Bienstock Karen
- Billouin-Frazier Shere
- Bissel Brittany
- Biswas Kousick
- Bjork Lauren
- Bledsoe Joseph
- Bojesen Ane
- Bokhart Gordon
- Bouffler Andrew
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- Cao Huyen
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- Carlsen Amy
- Carter Anita
- Casey Jonathan D
- Cash Jennifer
- Cassity Evan P
- Caudill Antonina
- Chang Christina C
- Chang Steven Y
- Chauhan Lakshmi
- Chen Peter
- Chi Andrew
- Chia Po Ying
- Chiu Charlene
- Chiu Joseph
- Choe June
- Choudhary Jay
- Clapham Gregg J
- Clariday Laura
- Clausen Clara Lundetoft
- Co Ivan N
- Coleman Tanquinisha
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- Crew Page
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- Currier Judy
- Davey Victoria J
- Davis Allyson
- Davis Bionca
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- Delp Alex
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- Dinh Huan
- Diong Shiau Hui
- Dishner Emma
- Dixon Mary
- Dolney Suzanne
- Douglas Ivor
- Douin David J
- Dreyer Grace R
- DuChateau Nadine
- DuChene Alain
- Duggal Abhijit
- Duhaime Erin
- Duque Krizia
- Eichinger Mareile L
- Eichman Sharon M
- Enfield Kyle B
- Engen Nicole
- Escobar Jose
- Esmann Frederik V.L
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- Evans Raquel
- Exposito Maria
- Eyler Carolyn
- Fabricius Thilde
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- Flores Lori S
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- Gammie James S
- Garcia Rebekah L
- Garcia-Myers Kelly
- Gardner Edward M
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- Gelijns Annetine C
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- Gerry Norman P
- Gerstoft Jan
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- Giangiacomo Dana M
- Gibbs Keven W
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- Hubel Kinsley A
- Huber Lynda
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- Hughes Eric
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- Jensen Tomas O
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- Jia Shijing
- Jibrell Hodan
- Joensen Zillah Maria
- Johansen Isik S
- Johnsen Stine
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- Jones Alan E
- Jones Felecia
- Jundgren Jens D
- Jurek Natalia
- Justino Chris
- Kadl Alexandra
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- Sánchez Adriana
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- Taddei-Peters Wendy C
- Talmor Daniel
- Terndrup Thomas E
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- Thisted Rikke Krog
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- Thompson Greg
- Thorlacius-Ussing Louise
- Thornton Kara
- Thornton-Thompson Sherell
- Tidswell Mark A
- Tien Phyllis
- Tierney John
- Tinggaard Michaela
- Tipple Craig
- Tipton Gregory
- Torbati Sam S
- Touloumi Giota
- Towfighi Amytis
- Tran Sonny
- Trautner Barbara W
- Treagus Amy
- Turner Emma
- Turner Melissa
- Tyler Derrick
- Tzehaie Hiwet
- Van John
- Vargas Julia
- Vasudeva Shikha
- Vekstein Andrew
- Villa Samantha
- Vincent Shelika
- Virachit Sophie
- Vjecha Michael
- Vock David M
- Voge Susan E
- Vojnik Rosemary
- von Huth Sebastian Leicht
- Vonderhaar Derek
- Wald-Dickler Noah
- Wallick Julie A
- Walski Jamie
- Wang Bonnie R
- Want Samantha
- Want Yiqun
- Watson Helen
- Watts Matthew
- Webb Brandon
- Weintrob Amy C
- Weissman Kevin
- Wenner Christine
- Wentworth Deborah
- West Emily
- Whitacre Heather
- Wiedemann Herbert P
- Wiese Lothar
- Williams Roger
- Willis Angela
- Wilson David M
- Wilson Jennifer G
- Witte Marie
- Woldbye Frederik
- Wyles David
- Wynter Timothy
- Yan Li
- Yee Kimberly J
- Yeo Tsin Wen
- Young Barnaby E
- Zheng Yiling
- Zhong Amy
- Zhu Qing
- Zhuo Hanjing
- Zink Veronika
- Zuckerman Judith
- Zuckerman Richard A
- Østergaard Lars
- Publication venue
- Elsevier Ltd
- Publication date
- 01/05/2022
- Field of study
We aimed to assess the efficacy and safety of two neutralising monoclonal antibody therapies (sotrovimab [Vir Biotechnology and GlaxoSmithKline] and BRII-196 plus BRII-198 [Brii Biosciences]) for adults admitted to hospital for COVID-19 (hereafter referred to as hospitalised) with COVID-19.
In this multinational, double-blind, randomised, placebo-controlled, clinical trial (Therapeutics for Inpatients with COVID-19 [TICO]), adults (aged ≥18 years) hospitalised with COVID-19 at 43 hospitals in the USA, Denmark, Switzerland, and Poland were recruited. Patients were eligible if they had laboratory-confirmed SARS-CoV-2 infection and COVID-19 symptoms for up to 12 days. Using a web-based application, participants were randomly assigned (2:1:2:1), stratified by trial site pharmacy, to sotrovimab 500 mg, matching placebo for sotrovimab, BRII-196 1000 mg plus BRII-198 1000 mg, or matching placebo for BRII-196 plus BRII-198, in addition to standard of care. Each study product was administered as a single dose given intravenously over 60 min. The concurrent placebo groups were pooled for analyses. The primary outcome was time to sustained clinical recovery, defined as discharge from the hospital to home and remaining at home for 14 consecutive days, up to day 90 after randomisation. Interim futility analyses were based on two seven-category ordinal outcome scales on day 5 that measured pulmonary status and extrapulmonary complications of COVID-19. The safety outcome was a composite of death, serious adverse events, incident organ failure, and serious coinfection up to day 90 after randomisation. Efficacy and safety outcomes were assessed in the modified intention-to-treat population, defined as all patients randomly assigned to treatment who started the study infusion. This study is registered with ClinicalTrials.gov, NCT04501978.
Between Dec 16, 2020, and March 1, 2021, 546 patients were enrolled and randomly assigned to sotrovimab (n=184), BRII-196 plus BRII-198 (n=183), or placebo (n=179), of whom 536 received part or all of their assigned study drug (sotrovimab n=182, BRII-196 plus BRII-198 n=176, or placebo n=178; median age of 60 years [IQR 50–72], 228 [43%] patients were female and 308 [57%] were male). At this point, enrolment was halted on the basis of the interim futility analysis. At day 5, neither the sotrovimab group nor the BRII-196 plus BRII-198 group had significantly higher odds of more favourable outcomes than the placebo group on either the pulmonary scale (adjusted odds ratio sotrovimab 1·07 [95% CI 0·74–1·56]; BRII-196 plus BRII-198 0·98 [95% CI 0·67–1·43]) or the pulmonary-plus complications scale (sotrovimab 1·08 [0·74–1·58]; BRII-196 plus BRII-198 1·00 [0·68–1·46]). By day 90, sustained clinical recovery was seen in 151 (85%) patients in the placebo group compared with 160 (88%) in the sotrovimab group (adjusted rate ratio 1·12 [95% CI 0·91–1·37]) and 155 (88%) in the BRII-196 plus BRII-198 group (1·08 [0·88–1·32]). The composite safety outcome up to day 90 was met by 48 (27%) patients in the placebo group, 42 (23%) in the sotrovimab group, and 45 (26%) in the BRII-196 plus BRII-198 group. 13 (7%) patients in the placebo group, 14 (8%) in the sotrovimab group, and 15 (9%) in the BRII-196 plus BRII-198 group died up to day 90.
Neither sotrovimab nor BRII-196 plus BRII-198 showed efficacy for improving clinical outcomes among adults hospitalised with COVID-19.
US National Institutes of Health and Operation Warp Spee
Prospective observational cohort study on grading the severity of postoperative complications in global surgery research
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- Abayasinghe Chamika
- Abbas Muntadhar
- Abbott T. E. F.
- Abbott Tom
- Abdullah Noor Hairiza
- Abdur-Rahman Lukman
- Abeloos Jacques
- Abernethy Caroline
- Abidin Ucu Nurhadiat
- Abrunhosa Alexandra
- Absar Mohammed
- Adam Suwayba
- Adams George
- Adamson Michael
- Adekola Oyebola
- Adelaja Yemi
- Ademola Adeyinka
- Adenekan Anthony
- Adenike Odewabi
- Adeolu Augustine A
- Adetoye Adedapo
- Adewale Badru
- Adigun Tinuola
- Adolfsson Anne
- Aflori Laura
- Africander Cucu
- Afshari Arash
- Agarwal Vandana
- Agodirin Olayide
- Aguzzoli Crisitiano
- Ahmad Abdurrahman
- Ahmad Norfaizan
- Ahmad T.
- Ahmad Tahania
- Ahmad Yousra
- Ahmed Ahmed
- Ahmed Jamil
- Ahmed Tahania
- Ai Yanqiu
- Aignatoaie Mariana
- Aimoniotou-Georgiou Eleni
- Akanmu Olanrewaju
- Akerman Nik
- Akinwale Mukaila
- Al Amri Khalid
- Al Hussaini Sabah
- Al-Soudaine Yassr
- Aladin Hafiz
- Alagbe-Briggs Olubusola
- Albaj Safauldeensalem
- Alcock David
- Alcock Liam
- Aldecoa Cesar
- Aldecoa Cesar
- Aleixo Fábia Berganton
- Alexander Hazel
- Alexander Maini
- Alexander-Sefre Farhad
- Alherz Fadhel
- Ali Hani
- Ali Marlynn
- Ali Sarah
- Alias Abdul Hafiz
- Alias Anita
- Alias Raja Liza Raja
- Allen Samantha
- Allen Sara Jane
- Allison Joanna
- Alloj Chiara
- Allorto Nikki Leigh
- Allsop Joanne
- Almeida William
- Alonso Eduardo
- Alonso José Ignacio
- Alphonsus Christella
- Alvares Danielle
- Alves Maria Joao
- Amador Juan Carlos Bravo
- Ameer Yusuf
- Amendola Cristina Prata
- Ami Noam
- Amstrup-Hansen Louise
- Anagnou Athina
- Andersen Cheme
- Anderson Charlotte
- Anderson Colette
- Anderson Frank
- Anderson Philip
- Andreadaki Evangelia
- Andreou Alexandros
- Andreou Prematie
- Andrew Alyson
- Andrews Emma
- Angel Miguel Paludi
- Angermair Stefan
- Angus Kirsty
- Anillo Victor
- Anizi Mashel Al
- Antal Oana
- Antill Philip
- Antoniadou Eleni
- Apagaki Eymorfia
- Apostolou Konstantinos
- Applewhaite Christopher
- Applewhaite Christopher
- Aquino Laura Patricia González
- Ar Praburaj
- Araujo Daniela Marques
- Arawwawala Dilshan
- Ardern Diane
- Argue Ruth
- Aribawa Mahaalit Alit
- Arkalaki Eleni
- Armaganidis Apostolos
- Armstrong John
- Armstrong Richard
- Arnaoutoglou Christina
- Arnaoutoglou Elena
- Arnold Glenn
- Arrandale Lindsay
- Arrich James
- Arrigo Mario
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- Deepak Shantal
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- Del Valle Santiago Garcia
- Delgado García David R
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- Denham Samuel
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- Dermitzaki Despina
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- Du Fang
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- Dudgeon Lucy
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- Foord Denise
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- Futier Emmanuel
- Futier Emmanuel
- Gaitanakis Stylianos
- Gall Lewis
- Gallacher Pete
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- Gallego Laura
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- Gambhir Rajiv
- Ganter Donna Louise
- Ganter Michael T
- Gao Hong
- Garcia Carolina Soledad Romero
- Garcia Juliana
- Garcia-Saiz Irene
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- Gardikou Varvara Vanessa
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- Garg Atul
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- Glasbey James
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- Glister Georgina
- Glover Lyn
- Goad Ehab Helmy Abdel
- Goebel Ulrich
- Goga Ismail E
- Goga Riaz
- Goldberg Olivia
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- Gondo Prisca
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- Granum Simon Nørgaard
- Graterol Juan
- Gratrix Karen
- Graves Lynne
- Gray Carol
- Gray Catherine
- Gray Sophie
- Greaves K. E.
- Greaves Rosanna
- Green Garyth M
- Green-Thompson Randolph
- Greene Michael
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- Grey Ben
- Griffiths Ewen
- Grigoras Ioana
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- Grintescu Ioana
- Grishkowez Elena
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- Guy Kramer
- Gätke Mona Ring
- Habicher Marit
- Hack Yvonne
- Haddow J.
- Haddow James
- Hadebe Bernard
- Hadfield Daniel
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- Hamilton Caroline
- Hamzah Zulkarnain
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- Hare Gregory
- Hariharan Vimal
- Harrichandparsad R
- Harries Rhiannon
- Harris Benjamin
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- Hennings Charles
- Hering Jens Peter
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- Hernandez Miguel
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- Hewson Russ
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- Hidayatullah Rahmat
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- Hinther Ashley
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- Hitchcock Rachael
- Hoare Siobhan
- Hobrok Maria
- Hodgkiss Tracey
- Hodgson Richard E
- Hodzovic Emil
- Hoedt Marielle
- Hoeft Andreas
- Hoeft Andreas
- Hofer Christoph
- Hofer Christoph
- Hoffer Franz
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- Incertis Raul
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- Janssen Bruno
- Januszewska Marta
- Januszewska Marta
- Jaquet Yves
- Jardim Jaquelline
- Jawad Monir
- Jee Chiun Chen
- Jeeraz Mohammud A
- Jeffery Holly
- Jeffs Carol
- Jehosua Brillyan
- Jelschen Florian
- Jemmett Kim
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- Jeyanthan Somasundaram
- Ji Binbin
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- Jones Timothy
- Joory Kavita
- Jordaan J
- Joseph James
- Jowitt Tom
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- Julian Howes
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- Kabagenyi Fiona
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- Kakembo Nasser
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- Kaunang Jonathan
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- Kaushik Shuchi
- Keen Abigail
- Keenan Samantha
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- Khalaf Abdel Razzaq
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- Kirk-Bayley Justin
- Kirov Mikhail
- Kirov Mikhail
- Kirya Fred
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- Klarin Bengt
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- Kobborg Tina
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- Koompirochana Vilavan
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- Kotsalas Nikolaos
- Kottam Lucksy
- Kougentakis Georgios
- Koulenti Despoina
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- Koutelidakis Ioannis
- Koutsikou Anastasia
- Kowalski Stephen
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- Krepil Adriana
- Kretov Vladimir
- Krishnachetty Bobby
- Kruse Carl-Heinz
- Krystopchuk Andriy
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- Kubitzek Christiane
- Kuhn Warren Paul
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- Kulkarni Aditi
- Kulkarni Atul
- Kulkarni Atul
- Kulkarni Raghavendra
- Kumar Pawan
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- Zhao Ting
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- Zhao Weilu
- Zhao Xiaoying
- Zhen Jungang
- Zheng Kang
- Zheng Lina
- Zheng Tianzhao
- Zhong Yi
- Zhou Ce
- Zhou Dachun
- Zhou Haidong
- Zhou Haiyan
- Zhou Jiali
- Zhou Jialong
- Zhou Jing
- Zhou Xian-jin
- Zhu Xiaomao
- Zhu Yi
- Zhu Zhipeng
- Zhuang Xiuxiu
- Zilis Georgios
- Zin Nor Hafizah Mohd
- Zingerle Nicolette
- Zingg Urs
- Zoerner Frank
- Zonneveldt Harry
- Zou Xiaohua
- Zoulamoglou Menelaos
- Zsisku Lajos
- Zundert Tom
- Zyl Rebekka
- åkring Irene
- Ögren Katrin
- Publication venue
- 'Wiley'
- Publication date
- 22/10/2018
- Field of study
Background
The Clavien–Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien–Dindo system can be used internationally in studies across differing healthcare systems in high- (HICs) and low- and middle-income countries (LMICs).
Methods
This was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospective observational cohort study of elective surgery in adults. Data collection occurred over a 7-day period. Severity of complications was graded using Clavien–Dindo and the simpler ISOS grading (mild, moderate or severe, based on guided investigator judgement). Severity grading was compared using the intraclass correlation coefficient (ICC). Data are presented as frequencies and ICC values (with 95 per cent c.i.). The analysis was stratified by income status of the country, comparing HICs with LMICs.
Results
A total of 44 814 patients were recruited from 474 hospitals in 27 countries (19 HICs and 8 LMICs). Some 7508 patients (16·8 per cent) experienced at least one postoperative complication, equivalent to 11 664 complications in total. Using the ISOS classification, 5504 of 11 664 complications (47·2 per cent) were graded as mild, 4244 (36·4 per cent) as moderate and 1916 (16·4 per cent) as severe. Using Clavien–Dindo, 6781 of 11 664 complications (58·1 per cent) were graded as I or II, 1740 (14·9 per cent) as III, 2408 (20·6 per cent) as IV and 735 (6·3 per cent) as V. Agreement between classification systems was poor overall (ICC 0·41, 95 per cent c.i. 0·20 to 0·55), and in LMICs (ICC 0·23, 0·05 to 0·38) and HICs (ICC 0·46, 0·25 to 0·59).
Conclusion
Caution is recommended when using a treatment approach to grade complications in global surgery studies, as this may introduce bias unintentionally
Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries
- Author
- A T Landers
- Aaron Lawson McLean
- Abbey Paton
- Abdel Razzaq Khalaf
- Abdul Hafiz Alias
- Abdurrahman Ahmad
- Abegail Salvana
- Abigail Keen
- Abigail Patrick
- Abraham Hulst
- Acela G Lopez
- Adam Evans
- Adam Rehak
- Adamu Muhammad Sarki
- Ade Nurkacan Dursin
- Ade Susanti
- Adela Ruiz
- Adeline Rankin
- Ademola Talabi
- Adenekan Adetoye
- Adeoluwa Tayo
- Adeyinka Ademola
- Aditi Kulkarni
- Aditi Naik
- Aditi Shrivastava
- Adriana Krepil
- Adrianna Woolsey
- Adrianna Woolsey
- Adrienne Carr
- Afolabi Owojuyigbe
- Aggeliki Bairaktari
- Agoritsa Tsioka
- Agostino Roasio
- Ahamed Khader
- Ahmad Sufian Ab Rahman
- Ahmed Ahmed
- Ahmed El-Sayed
- Ahmed Saloojee
- Ahmed Sayeed
- Aida Tantri
- Aida Tantri
- Aikaterini Chatzimichali
- Aikaterini Kyparissi
- Aikaterini Makatounaki
- Aisling Clarkson
- Ajay Gupta
- Akanmu Durodola
- Akbar Vohra
- Akbar Vohra
- Akbar Vohra
- Akbar Vohra
- Akram Fuad
- Alae Conradie
- Alasdair Scott
- Alastair Rose
- Alba Perez Gonzalez
- Albert Tsui
- Alberto Lisi
- Alberto Premoli
- Alberto Ramirez
- Alberto Zangrillo
- Alda Martins
- Aleaxandra Moustaka
- Alejandra Romero Rodrigo
- Alejandro Duca
- Alejandro Suarez-de-la-Rica
- Aleksandr Iurin
- Aleksandr Molkov
- Aleksandr Samoilenko
- Aleksandr Tchekulaev
- Alessandra Bettinelli
- Alessandro Gatta
- Alessandro Marchesi
- Alex Looseley
- Alex Ragan
- Alexander Bates
- Alexander Chan
- Alexander Durst
- Alexander Fowler
- Alexander Freethy
- Alexander Ishimaru
- Alexander Kulikov
- Alexander Tolmasov
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- Alexandra Charlalampidoy
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- Mohammed Absar
- Mohammed Asif Arshad
- Mohammed Shazad Khalid
- Mohammud A Jeeraz
- Mohan Babu Muthuswamy
- Mohanakrishnan Shanmugam
- Mohd Azuan Ab Majid
- Mohd Tarmimi Bin Mustapha
- Mona Momeni
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- Monica Hutton
- Monir Jawad
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- Moritz Meyer Zu Schwabedissen
- Morten Daugaard
- Motshedisi Sebitloane
- Mueen Saley
- Muhamad Faiz Norddin
- Mukaila Akinwale
- Muntadhar Abbas
- Murray J Smith
- Myles Boone
- N Sibusiso Gama
- Na Hu
- Na Tang
- Nabilah Hussain
- Nadine Wickboldt
- Nadir Ratanshi
- Naeder Helmy
- Nahla Farid
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- Neil Smith
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- Nigel Dunk
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- Nik Akerman
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- Nimu Varsani
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- Oluyemi Fasina
- Omer Omer
- Omowunmi Olaleye
- Orestis Ioannidis
- Orsolya Minik
- Osama Montasser
- Osne Kirzner
- Otto Mohr
- Ourania Ververidou
- Oyebola Adekola
- Paloma Poza
- Panagiota Gkioni
- Panagiota Niforopoulou
- Panagiota Ntouma
- Panagiotis Chaloulis
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- Panagoula Daikou
- Pandora Chua
- Panna Patel
- Paola Valls
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- Pastor Luna
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- Patrick Wouters
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- Priya Somascanthan
- Punitha Vandenbempt
- Pushan Chen
- Qi Bao
- Qi Shan
- Qiang Chen
- Qiang Liu
- Qianjun Li
- Qin Zhang
- Qing-Tao Meng
- Qingqing Dai
- Qinxue Dai
- Qiong Wu
- Qiong Xu
- Qisheng Liang
- Qiuhong Yang
- Qiuting Zeng
- Quan Ren
- R Harrichandparsad
- Rachael Bennett
- Rachael Craven
- Rachael Dolan
- Rachael Hitchcock
- Rachel Bell
- Rachel Bell
- Rachel Christian
- Rachel Horn
- Rachel Lyons
- Rachel Pearson
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- Rachel Walker
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- Raja Liza Raja Alias
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- Rajesh Ramjee
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- Rajkumar Rajendram
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- Ravikiran Shenoy
- Ravinder Vohra
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- Reinhold Klug
- Reitze Nils Rodseth
- Renee Ewe
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- Riaan Liebenberg
- Riaz Goga
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- Richard Halliwell
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- Roel Matos-Puig
- Roger Hall
- Roger Schmid
- Rohan Prakash
- Romilla Franks
- Ronald Carrera
- Ronald George
- Ronald George
- Ronald George
- Rondall Lane
- Ronelle Mouton
- Rong Chen
- Rong Hu
- Roopa McCrossan
- Rory Riddell
- Rosanna Greaves
- Rosanna Varden
- Rose Damant
- Rose English
- Roshan Rao
- Rosie Dudson
- Ross Cruickshank
- Ross Kennedy
- Ross Kerridge
- Rotimi Peter Olonisakin
- Rubendraj R Chetty
- Rubeshan Naidoo
- Rudy Harris
- Rui Freitas Mendonça Correia da Silva
- Rui Moreno
- Rui Moreno
- Rui Xue
- Ruilin Zhang
- Rune Sarauw Lundsgaard
- Rupert Broomby
- Rupert M Pearse
- Rupert M. Pearse
- Rusnah Ab Rahman
- Russ Hewson
- Russell Hewson
- Ruth Argue
- Ruvashni Naidoo
- Ryan Humphries
- Ryan Salter
- Sabah Al Hussaini
- Sabine Ethgen
- Safauldeensalem Albaj
- Sahayam Santa
- Sahely Flores Risco
- Saiful Aizar Kesut
- Sailaja Pothuneedi
- Sailaja Pothuneedi
- Salim Tayeh
- Sally Anne Pearson
- Sally Humphreys
- Sally Wright
- Salome Cruz
- Salvador Fernández
- Sam Montasser
- Sam Papadopoullos
- Samantha Allen
- Samantha Keenan
- Sameer Garg
- Sameer Somanath
- Samir Patel
- Samson Tou
- Samuel Denham
- Sanda Maria Copotoiu
- Sandeep Varma
- Sandra Dias
- Sandra Holmström
- Sandra Jumbe
- Sanghamitra Mishra
- Sanjay Shah
- Sanjeev Garg
- Santiago Garcia Del Valle
- Saoirse Lyons
- Sara Jane Allen
- Sara Lyckner
- Sara Pick
- Sara Pick
- Sara Rêgo
- Sara Scott
- Sarah Ali
- Sarah Bates
- Sarah Bowrey
- Sarah Buckley
- Sarah Cavanagh
- Sarah Cooper
- Sarah Craw
- Sarah Harris
- Sarah James
- Sarah Mills
- Sarah Moreton
- Sarah Rasip
- Sarah Scourfield
- Sarah Welsh
- Sarah Williams
- Satwant Gill
- Satwant Kaur
- Saul Sundayi
- Saul Velaz Dominguez
- Savino Spadaro
- Scott Beattie
- Scott Beattie
- Scott Beattie
- Scott Nicol
- Sean Mcmullan
- Sebastian Tranca
- Seigne Richard
- Seleen Cheah
- Selina Sewpersad
- Semarawima Wima
- Serge Molliex
- Sergey Puzanov
- Sergi Tormo
- Shafa Ullah
- Shailendra Sham
- Shalil Solanki
- Shan Luo
- Shane McQuoid
- Shanglong Yao
- Shantal Deepak
- Shara McDonald
- Shardha Chandrasekharan
- Sharif Darwish
- Sharon Cacala
- Sharon Cotterell
- Shasha Chen
- Shashikant Yegnaram
- Shaun Naidoo
- Sheba Predeep
- Shelley Baillie
- Sheng Wang
- Shenhui Jin
- Shenhui Wang
- Sheraz Markar
- Sherezade Tovar Doncel
- Sheshagiri Bengeri
- Sheshendrasurian Visvalingam
- Shihai Zhang
- Shilpaja Karpate
- Shirley Pyke
- Shiv Chande
- Shiva Tripathi
- Shiva Tripathi
- Shixia Xu
- Shiyu Chen
- Shobhit Arya
- Shu Kai Ma
- Shuangfei Hu
- Shuangjia Yang
- Shuchi Kaushik
- Shuchun Yu
- Shuijing Wu
- Shun Wang
- Shuna Zhao
- Shuying Fu
- Si Yuan Dai
- Sian Gallard
- Sian Thomas
- Sibongile J Mothae
- Siegfried Veit
- Siew Ching Tan
- Sigismond Lasocki
- Sijia Chen
- Silvano Cardellino
- Silvia Martín
- Silvia Sanchez-Morcillo
- Simao Esteves
- Simeon Olateju
- Simon Bisgaard Heintzelmann
- Simon Chau
- Simon Davis
- Simon Hill
- Simon Large
- Simon Lawson
- Simon Lewthwaite
- Simon Nørgaard Granum
- Simon Pickard
- Simon Varley
- Simona Margarit
- Simone Haselberger
- Sindiswa Ntloko
- Sinead Kelly
- Siobhan Hoare
- Sofia Kokkini
- Sofia Marques
- Sofia Serra
- Solange R Nahum
- Somasundaram Jeyanthan
- Song Huang
- Sonia Sampson
- Sonja Meier
- Sonya Daniel
- Sophia Tsiligiannis
- Sophie Gray
- Sophie Mathoulin
- Sotannde Sola
- Sotirios Bristogiannis
- Sotirios Georgios Popeskou
- Speranza Bocchino
- Spyros Zakynthinos
- Srikanth Chukkambotla
- Stanislav Pugachev
- Stavros Tsampalas
- Stefaan Bouchez
- Stefan Angermair
- Stefan Breitenstein
- Stefan de Hert
- Stefan De Hert
- Stefan Wildi
- Stephan Holliger
- Stephan Thilen
- Stephanie Bell
- Stephanie Jones
- Stephen Barrett
- Stephen Choi
- Stephen John Roberts
- Stephen Kowalski
- Stephen P Blakemore
- Stephen Phillips
- Stephen Webb
- Stephens Robert
- Steve Rose
- Steve White
- Steven Kim
- Steven Kleopoulos
- Steven Takemoto
- Steyn van Wyk
- Stuart White
- Stylianos Gaitanakis
- Stylianos Karatzas
- Stéphane de Rudnicki
- Su Meng
- Subash Chirkut
- Sudha Bechan
- Sudheer Karlakki
- Sue Hesketh
- Sue Olliff
- Suhas Kumar
- Sujith Basanth
- Sukhada Savarkar
- Sukumar Nagaiah
- Suman Mewa Kinoo
- Sumara Niman
- Sumayer Sanghera
- Sumitra Lahiri
- Suneetha Venugopal
- Sunny Karadia
- Suparna Das
- Suren R Ramphal
- Susan Melbourne
- Susan Smolen
- Susanna Chu
- Susanne Sonnemann
- Susanne Sonnemann
- Susilo Chandra
- Susilo Chandra
- Suwayba Adam
- Suzana Lobo
- Suzana M Lobo
- Suzanne Coulter
- Suzanne Odeberg-Wernerman
- Svenja Pabel
- Swarna Arumugam
- Swarna Baskar Sharma
- Swati Karmarkar
- Swati Pande
- Sze Meng Wong
- Sérgio Baldisserotto
- Søren Hübertz Smith
- Taeyang Kim
- Tahania Ahmad
- Tahania Ahmed
- Talvinder Gill
- Tamara Brunete
- Tamas Szakmany
- Tamas Szakmany
- Tanaka Muzenda
- Tania Socorro Artiles
- Tara Campbell
- Tara Walker
- Tarek Bejia
- Tariq Deen
- Tatiana Lefaki
- Tatiana Slepova
- Tauqeer Husain
- Tejal Dave
- Temlett Emma
- Tengku Alini Tengku Lih
- Teresa Branco
- Teresa Rotunno
- Terry Martin
- Tesuven K Naidu
- Thais Creary
- Thalissa Hermínia Baio
- Thandinkosi E Madiba
- Thelma Commey
- Theodora Christodoulopoulou
- Theodora Melissopoulou
- Theodosios Theodosopoulos
- Theoniki Paraforou
- Theonymfi Papavasilopoulou
- Theophilos Rozenberg
- Thiago Motta Netto
- Thinagrin Dhasarthun Naidoo
- Thomas Bührer
- Thomas Daubeny
- Thomas Egan
- Thomas Hillermann
- Thomas Hopkins
- Thomas Hughes
- Thomas Jared McCormick
- Thomas Jared McCormick
- Thomas Mayrhofer
- Thomas McCormick
- Thomas Mencke
- Thomas Owen
- Thomas Parsons
- Thomas Smith
- Thuli Biyase
- Tiago do Nascimento Cabral
- Tian Yu
- Tianlong Wang
- Tianqin Yang
- Tianzhao Zheng
- Tim Cook
- Tim Short
- Timothy Jones
- Timothy McCulloch
- Timothy Salmond
- Tina Kobborg
- Ting Zhao
- Tingju Hu
- Tinuolac Adigun
- Tjokorda Gde Agung Senapathi
- Tokunbo Olajumoke
- Tom Abbott
- Tom Burrows
- Tom Jacobs
- Tom Jowitt
- Tom Lawson
- Tom Lawton
- Tom van Zundert
- Tonia Onyeka
- Tony Smith
- Tony Wong
- Tracey Hodgkiss
- Tracey Lowery
- Tracey Nolan
- Tracey Nolan
- Tracey Roberts
- Tracy Lam
- Tracy Norton
- Tracy-Lee Jansen
- Tressy Pitt-Kerby
- Troy Wildes
- Tse Siang Tan
- Tunde Osinaike
- Ucu Nurhadiat Abidin
- Ulf Kessler
- Ulrich Goebel
- Ulrika Winstone
- Uma Shastri
- Umar Musa Sule
- Ummi Azmira Ahmad Azam
- Urs Zingg
- Utara Hartawan Utara
- Vaia Aliki Rompou
- Valentin Tutunaru
- Valentina Paola Plumari
- Valentina Testa
- Valentina Tulupova
- Valerie Banner-Goodspeed
- Valerie Serra Maudet
- Valerie Smit-Fun
- Valeriy Levin
- Vandana Agarwal
- Vanessa Beavis
- Vanessa Beavis
- Vanessa Beavis
- Vanessa Nesbitt
- Varvara Vanessa Gardikou
- Vasileia Nyktari
- Vasileios Despotidis
- Vasileios Kalles
- Vasileios Ourailoglou
- Vasilios Bouris
- Vasilios Koulouras
- Veerle Van Mossevelde
- Vera Guttenthaler
- Veronica Cherrett
- Veronika Cakova
- Vicari Sottosanti
- Vicente Chisbert Cuenca
- Vicky Hills
- Victor Anillo
- Victor Aspelund Liljequist
- Victor Ionita
- Victor Raji
- Victoria Bennett
- Victoria Boggiano
- Victoria Freeman
- Victoria Frost
- Victoria Lambourne
- Victoria Martinson
- Victoria Phelps
- Vieri Parrini
- Vikas Kaura
- Vilavan Koompirochana
- Vimal Hariharan
- Vincent Chan
- Vineshykaa Ramesh Kumar
- Vinícius Nascimento
- Vishal Narwani
- Vishendran Govindasamy
- Vivek Sinha
- Vivesh Rughubar
- Vlad Kushakovsky
- Vladimir Kretov
- Vladislav Belskiy
- Vukani T Manzini
- Vítor Miguel Pinho-Oliveira
- Wai Cheong Soon
- Wai Kit Jacky Chan
- Wangpin Xiao
- Warren Paul Kuhn
- Wei Ren
- Wei Xiao
- Weihong Zhao
- Weilin Sung
- Weilu Zhao
- Weiwei Zhang
- Weixing Wang
- Wendy Bertram
- Wendy Joan Barrett
- Weng Ken Chan
- Wenhui Huang
- Werner Schmid
- Werner Schmid
- Weslley Mendes
- Widnyana Made Wid
- William Almeida
- William Foers
- William Peat
- Wilson Binh Quan Huynh
- Wilson Fabio Serna Martínez
- Wilton van Klei
- Wing LamWong
- Wing Sze Li
- Wing Yan Lam
- Wiryana Made Wir
- Wolfgang Buhre
- Wolfgang Buhre
- Wujun Geng
- Xenia Souvatzis
- Xian-Jin Zhou
- Xianfu Lu
- Xiangming Fang
- Xianwen Hu
- Xiao Hong Wen
- Xiaocui Lv
- Xiaodong Ge
- Xiaodong Qiu
- Xiaoguang Zhang
- Xiaohua Zou
- Xiaolan Hu
- Xiaolin Zhang
- Xiaomao Zhu
- Xiaoqin Li
- Xiaoyan Zhang
- Xiaoying Li
- Xiaoying Zhao
- Xiaoyu Li
- Xiaoyun Shi
- Xiapei Xiong
- Xin He
- Xindan Du
- Xinjian Lu
- Xinmei Jiang
- Xinyu Qi
- Xiu-Li Wang
- Xiumei Song
- Xiuxiu Zhuang
- Xuewu Lin
- Xuming Hu
- Yan Jing
- Yan Leng
- Yan Pan
- Yan Zhang
- Yana Ilyina
- Yanbing Bi
- Yanfei Xia
- Yang Liu
- Yang Yang
- Yangwen Ou
- Yangyang Han
- Yanling Li
- Yanming Huang
- Yanqiu Ai
- Yapping Zhang
- Yaqi Li
- Yaqiu Chen
- Yassr Al-Soudaine
- Yavor Metodiev
- Yazhou Wen
- Yazhuo Yuan
- Ye Zhang
- Yelong Ren
- Yemi Adelaja
- Yetong Li
- Yew Ching Lee
- Yi Liu
- Yi Zhong
- Yi Zhu
- Yijiao Chen
- Yijun Chen
- Yik Lam Chan
- Ying Cao
- Yingfen Xiong
- Yingping Liang
- Yixiu Yan
- Yiyi Shi
- Yonghao Yu
- Yongjie Chen
- Yongqing Guo
- Yongtao Sun
- Yongzhong Tang
- Yoni van Duivenvoorde
- Youliang Tong
- Yousif Saeed
- Yousra Ahmad
- Yu Fan
- Yu Sun
- Yuan Hsuan Chang
- Yuan Liang Woon
- Yuan Zhang
- Yuanming Pan
- Yuanyuan Pan
- Yue Fei
- Yuehong Qi
- Yuejiang Liu
- Yuelan Wang
- Yugang Shi
- Yuhong Li
- Yuksel Gercek
- Yun Bai
- Yun Ren
- Yunbin Fu
- Yunchang Mo
- Yunfei Cai
- Yunlin Feng
- Yunzhi Ling
- Yurui Yao
- Yushio Cheing
- Yusuf Ameer
- Yuting Wang
- Yves Jaquet
- Yvonne Hack
- Yvonne Selibea
- Zaheer Moolla
- Zaid Makzal
- Zane Farina
- Zhang Chen
- Zhen Dan Peng
- Zhen Wang
- Zhen Wang
- Zheng Guo
- Zhengyuan Liu
- Zhenrong Ji
- Zhi Wang
- Zhipeng Wang
- Zhipeng Zhu
- Zhisong Li
- Zhiting Wen
- Zhong-Yuan Xia
- Zhongming Cao
- Zi-Ying Shen
- Zin Nico
- Ziqiang Miao
- Zoe Davies
- Zoe Drinkwater
- Zoe Whitman
- Zulkarnain Hamzah
- Álvaro Réa-Neto
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
This was an investigator initiated study funded by Nestle Health Sciences through an unrestricted research grant, and by a National Institute for Health Research (UK) Professorship held by RP. The study was sponsored by Queen Mary University of London