280 research outputs found

    ADTH: Bounded Nodal Delay for Better Performance in Wireless Ad-hoc Networks

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    © 2018 Delay is an unavoidable factor that occurs within networks and may be exacerbated by the nature of wireless ad-hoc networks. Maintaining a manageable level of delay may be required to provide satisfactory performance for each of the nodes that form the network. The variability of IoT devices, topologies and network conditions demand that a standalone and scalable scheme be used. ADTH is first shown to accomplish this through simulations with the NS-2 network simulator. The scheme was then used with testbed implementation with Gumstix devices and real-time traffic provided by an STC Traffic Generator. These demonstrated its effectiveness in managing flows of delay sensitive traffic, in addition to delivering superior bandwidth utilisation than standard policies

    A Systematic Analysis of the Lepton Polarization Asymmetries in the Rare B Decay, B -> X_s\tau^+\tau^-

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    The most general model-independent analysis of the lepton polarization asymmetries in the rare B decay, \Bstt, is presented. We present the longitudinal, normal and transverse polarization asymmetries for the τ+\tau^+ and τ−\tau^-, and combinations of them, as functions of the Wilson coefficients of twelve independent four-Fermi interactions, ten of them local and two nonlocal. These procedures will tell us which type of operators contributes to the process. And it will be very useful to pin down new physics systematically, once we have the experimental data with high statistics and a deviation from the Standard Model is found.Comment: 24 pages, 8 figures, LaTe

    Solar Neutrinos: What We Have Learned

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    The four operating solar neutrino experiments confirm the hypothesis that the energy source for solar luminosity is hydrogen fusion. However, the measured rate for each of the four solar neutrino experiments differs significantly (by factors of 2.0 to 3.5) from the corresponding theoretical prediction that is based upon the standard solar model and the simplest version of the standard electroweak theory. If standard electroweak theory is correct, the energy spectrum for \b8 neutrinos created in the solar interior must be the same (to one part in 10510^5) as the known laboratory \b8 neutrino energy spectrum. Direct comparison of the chlorine and the Kamiokande experiments, both sensitive to \b8 neutrinos, suggests that the discrepancy between theory and observations depends upon neutrino energy, in conflict with standard expectations. Monte Carlo studies with 1000 implementations of the standard solar model confirm that the chlorine and the Kamiokande experiments cannot be reconciled unless new weak interaction physics changes the shape of the \b8 neutrino energy spectrum. The results of the two gallium solar neutrino experiments strengthen the conclusion that new physics is required and help determine a relatively small allowed region for the MSW neutrino parameters.Comment: LaTeX file, 19 pages. For hardcopy with figures contact [email protected]. Institute for Advanced Study number AST 93/6

    A search for periodic modulations of the solar neutrino flux in Super-Kamiokande-I

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    A search for periodic modulations of the solar neutrino flux was performed using the Super-Kamiokande-I data taken from May 31st, 1996 to July 15th, 2001. The detector's capability of measuring the exact time of events, combined with a relatively high yield of solar neutrino events, allows a search for short-time variations in the observed flux. We employed the Lomb test to look for periodic modulations of the observed solar neutrino flux. The obtained periodogram is consistent with statistical fluctuation and no significant periodicity was found

    Fine-Scale Mapping of the 5q11.2 Breast Cancer Locus Reveals at Least Three Independent Risk Variants Regulating MAP3K1

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    International Lower Limb Collaborative (INTELLECT) study : a multicentre, international retrospective audit of lower extremity open fractures

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    The genetic architecture of the human cerebral cortex

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    INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities. Variations in human cortical surface area and thickness are associated with neurological, psychological, and behavioral traits and can be measured in vivo by magnetic resonance imaging (MRI). Studies in model organisms have identified genes that influence cortical structure, but little is known about common genetic variants that affect human cortical structure. RATIONALE To identify genetic variants associated with human cortical structure at both global and regional levels, we conducted a genome-wide association meta-analysis of brain MRI data from 51,665 individuals across 60 cohorts. We analyzed the surface area and average thickness of the whole cortex and 34 cortical regions with known functional specializations. RESULTS We identified 306 nominally genome-wide significant loci (P < 5 × 10−8) associated with cortical structure in a discovery sample of 33,992 participants of European ancestry. Of the 299 loci for which replication data were available, 241 loci influencing surface area and 14 influencing thickness remained significant after replication, with 199 loci passing multiple testing correction (P < 8.3 × 10−10; 187 influencing surface area and 12 influencing thickness). Common genetic variants explained 34% (SE = 3%) of the variation in total surface area and 26% (SE = 2%) in average thickness; surface area and thickness showed a negative genetic correlation (rG = −0.32, SE = 0.05, P = 6.5 × 10−12), which suggests that genetic influences have opposing effects on surface area and thickness. Bioinformatic analyses showed that total surface area is influenced by genetic variants that alter gene regulatory activity in neural progenitor cells during fetal development. By contrast, average thickness is influenced by active regulatory elements in adult brain samples, which may reflect processes that occur after mid-fetal development, such as myelination, branching, or pruning. When considered together, these results support the radial unit hypothesis that different developmental mechanisms promote surface area expansion and increases in thickness. To identify specific genetic influences on individual cortical regions, we controlled for global measures (total surface area or average thickness) in the regional analyses. After multiple testing correction, we identified 175 loci that influence regional surface area and 10 that influence regional thickness. Loci that affect regional surface area cluster near genes involved in the Wnt signaling pathway, which is known to influence areal identity. We observed significant positive genetic correlations and evidence of bidirectional causation of total surface area with both general cognitive functioning and educational attainment. We found additional positive genetic correlations between total surface area and Parkinson’s disease but did not find evidence of causation. Negative genetic correlations were evident between total surface area and insomnia, attention deficit hyperactivity disorder, depressive symptoms, major depressive disorder, and neuroticism. CONCLUSION This large-scale collaborative work enhances our understanding of the genetic architecture of the human cerebral cortex and its regional patterning. The highly polygenic architecture of the cortex suggests that distinct genes are involved in the development of specific cortical areas. Moreover, we find evidence that brain structure is a key phenotype along the causal pathway that leads from genetic variation to differences in general cognitive function

    Multiplicity dependence of inclusive J/psi production at midrapidity in pp collisions at root s=13 TeV

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    Measurements of the inclusive J/psi yield as a function of charged-particle pseudorapidity density dN(ch)/d eta in pp collisions at root s = 13 TeV with ALICE at the LHC are reported. The J/psi meson yield is measured at midrapidity (vertical bar y vertical bar <0.9) in the dielectron channel, for events selected based on the charged-particle multiplicity at midrapidity (vertical bar eta vertical bar <1) and at forward rapidity (-3.7 <eta <-1.7 and 2.8 <eta <5.1); both observables are normalized to their corresponding averages in minimum bias events. The increase of the normalized J/psi yield with normalized dN(ch)/d eta is significantly stronger than linear and dependent on the transverse momentum. The data are compared to theoretical predictions, which describe the observed trends well, albeit not always quantitatively. (C) 2020 European Organization for Nuclear Research. Published by Elsevier B.V.Peer reviewe
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