Predictors of dropout in the German disease management program for type 2 diabetes

Background: To improve and assess the effectiveness of disease management programs (DMPs), it is critical to understand how many people drop out of disease management programs and why. Methods: We used routine data provided by a statutory health insurance fund from the regions North Rhine, North Wurttemberg and Hesse. As part of the German DMP for type 2 diabetes, the insurance fund received regular documentation of all members participating in the program. We followed 10,989 patients who enrolled in the DMP between July 2004 and December 2005 until the end of 2007 to study how many patients dropped out of the program. Dropout was defined based on the discontinuation of program documentation on a particular patient, excluding situations in which the patient died or left the insurance fund. Predictors of dropout, assessed at the time of program enrolment, were explored using logistic regression analysis. Results: 5.5% of the patients dropped out of the disease management program within the observation period. Predictors of dropout at the time of enrolment were: region; retirement status; the number of secondary diseases; presence of a disabling secondary disease; doctors recommendations to stop smoking or to seek nutritional counselling; and the completion and outcome of the routine foot and eye exams. Different trends of dropout were observed among retired and employed patients: retired patients of old age, who possibly drop out of the program due to other health care priorities and employed people of younger age who have not yet developed many secondary diseases, but were recommended to change their lifestyle. Conclusions: Overall, dropout rates for the German disease management programs for type 2 diabetes were low compared to other studies. Factors assessed at the time of program enrolment were predictive of later dropout and should be further studied to provide information for future program improvements

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Influence of Feeding Compound Feed Rich in Fibre during Parturition and Lactation on Health and Performance of Sows

The aim of this study was to investigate the influence of ad libitum access to compound feeds rich in fibre (ante partum (a.p.) and peri partum) on the DM intake, body mass development and performance of sows as well as excretion of Clostridium (C.) perfringens via sows’ faeces. From day 109 (d-7) of gestation, 25 of 48 sows (23 considered as control) received access to one of two different high-fibre pellets from d-7 until the second day post partum (p.p.) (d2) (fibre groups (FG) 1 and 2) in additional to a lactation diet. The additional DM intake of the high-fibre pellets a.p. was 2.13 ± 1.15 kg in FG 1 and 3.14 ± 0.68 kg in FG 2. This led to higher DM intake in the first lactation week and significantly lower losses of weight and back fat thickness during lactation. The bacterial counts of C. perfringens in sows’ faeces directly p.p. were 10 times lower in FG 1 and 100 times lower in FG 2 compared to the controls. High amounts of fibre led to higher DM intake throughout lactation, which had beneficial effects on sows’ body conditions. It seems that high fibre intake influenced the excretion of C. perfringens at parturition, which could improve the health of newborns

Mikrostruktur und Textur nach Scherverformungsversuchen an Hämatiterzen

Die Beziehungen zwischen der Mikrostruktur und der kristallografischen Vorzugsorientierung (Textur) von Hämatiterzen der gebänderten Eisenerzformation (BIF) in Brasilien wurden in vielen Veröffentlichungen behandelt, z.B. Quade et. al. 2000, Rosière et al. 2001, Bascou et al. 2002. Polfiguren dieser Hämatiterze zeigen kreisförmige bis elliptische c-Achsen-Maxima, die um den Pol der Foliation liegen. Die Pole der Prismenflächen liegen auf Großkreisen in der Foliationsebene und die Maxima auf diesen fallen mit der Lineation zusammen. Die Entstehung dieser Regelung wird auf Scherverformungprozesse zurückgeführt. Bei experimentellen Stauchversuchen an polykristallinem Hämatit gab es Anzeichen der Bildung eines c-Achsenmaximums senkrecht zur Kompressionsrichtung (Siemes et al. 2003). Da zu vermuten war, dass Gleiten parallel zur Basis des Hämatits Ursache der Regelung ist, wurden die Gleitmechanismen an experimentell verformten Hämatiteinkristallen bestimmt (Siemes et al. 2006). In diesem Beitrag werden neue Scherexperimente an polykristallinen Hämatitaggregaten vorgestellt...conferenc