A Gamma Ray Burst with a 220 Microsecond Rise Time and a Sharp Spectral Cutoff

The Gamma Ray Burst GRB920229 has four extreme and unprecedented properties; a rise in brightness with an e-folding time scale of $220 \pm 30 \mu s$, a fall in brightness with an e-folding time scale of $400 \pm 100 \mu s$, a large change in spectral shape over a time of $768 \mu s$, and a sharp spectral cutoff to high energies with $\Delta E/E = 18$. The rapid changes occur during a spike in the light curve which was seen 0.164 s after the start of the burst. The spectrum has a peak $\nu F_{\nu}$ at 200 keV with no significant flux above 239 keV, although the cutoff energy shifts to less than 100 keV during the decay of the spike. These numbers can be used to place severe limits on fireball models of bursts. The thickness of the energy production region must be smaller than $\sim 66 km$, ejected shells must have a dispersion of the Lorentz factor of less than roughly 1% along a particular radius, and the angular size of the radiation emission region is of order 1 arc-minute as viewed from the burst center. The physical mechanism that caused the sharp spectral cutoff has not been determined.Comment: 20 pages, 3 figures, Submitted to ApJ

Quotient groups of the fundamental groups of certain strata of the moduli space of quadratic differentials

In this paper, we study fundamental groups of strata of the moduli space of quadratic differentials. We use certain properties of the Abel-Jacobi map, combined with local surgeries on quadratic differentials, to construct quotient groups of the fundamental groups for a particular family of strata.Comment: 43 pages, 7 figures. Version 2: Minor typos fixed, Section 3 removed and may now be found in arXiv:0804.043

Gamma-ray bursts have millisecond variability

We have performed searches for isolated flares and for steady flickering in the initial ∼ 1 s of gamma-ray burst light curves on the microsecond to millisecond timescales. Two bursts among our sample of 20 revealed four isolated flares with timescales from 256 to 2048 μs. A wavelet analysis for our sample showed low-level flickering for all bursts on timescales from 256 μs to 33 ms, with the majority of bursts containing rise times faster than 4 ms and 30% having rise times faster than 1 ms. These results show that millisecond variability is common in classical bursts and not some exceptional activity by a possibly separate class of bursts. These fast rise times can be used to place the following severe limits on burst models. (1) The characteristic thickness of the energy generation region must be less than 1200 km along the line of sight. (2) The angular size of the gamma-ray emission region as subtended from the central source must be less than 42″. (3) The expanding ejecta must have a range of Lorentz factors along a radius line with a dispersion of less than roughly 2%. (4) Within the external shock scenario, the characteristic dimension of the impacted cloud must be smaller than 16 AU on average. (5) Within the collimated jet scenario, the collimation angle must be smaller than 42″

Orphans of the AIDS epidemic? The extent, nature and circumstances of child-headed households in South Africa

There is widespread concern that the number of children living in “child-headed households” is rapidly increasing as a result of AIDS-related adult mortality in much of sub-Saharan Africa. Based on analyses of data from several representative national surveys over the period 2000–2007, this paper examines the extent to which this is the case in South Africa. It explores trends in the number of children living in child-only households and characterises these children relative to children living in households with adults (mixed-generation households). The findings indicate that the proportion of child-only households is relatively small (0.47% in 2006) and does not appear to be increasing. In addition, the vast majority (92.1%) of children resident in child-only households have a living parent. The findings raise critical questions about the circumstances leading to the formation of child-only households and highlight that they cannot for the main part be ascribed to HIV orphaning. Nonetheless, the number of children living in this household form is not insignificant, and their circumstances, when compared with children in mixed-generation households, indicate a range of challenges, including greater economic vulnerability and inadequate service access. We argue that a solitary focus on the HIV epidemic and its related orphaning as the cause of child-only households masks other important issues for consideration in addressing their needs, and risks the development of inappropriate policies, programmes and interventions

CMZoom III: Spectral Line Data Release

We present an overview and data release of the spectral line component of the SMA Large Program, \textit{CMZoom}. \textit{CMZoom} observed $^{12}$CO(2-1), $^{13}$CO(2-1) and C$^{18}$O(2-1), three transitions of H$_{2}$CO, several transitions of CH$_{3}$OH, two transitions of OCS and single transitions of SiO and SO, within gas above a column density of N(H$_2$)$\ge 10^{23}$\,cm$^{-2}$ in the Central Molecular Zone (CMZ; inner few hundred pc of the Galaxy). We extract spectra from all compact 1.3\,mm \emph{CMZoom} continuum sources and fit line profiles to the spectra. We use the fit results from the H$_{2}$CO 3(0,3)-2(0,2) transition to determine the source kinematic properties. We find $\sim 90$\% of the total mass of \emph{CMZoom} sources have reliable kinematics. Only four compact continuum sources are formally self-gravitating. The remainder are consistent with being in hydrostatic equilibrium assuming that they are confined by the high external pressure in the CMZ. Based on the mass and density of virially bound sources, and assuming star formation occurs within one free-fall time with a star formation efficiency of $10\% - 75\%$, we place a lower limit on the future embedded star-formation rate of $0.008 - 0.06$\,M$_{\odot}$\,yr$^{-1}$. We find only two convincing proto-stellar outflows, ruling out a previously undetected population of very massive, actively accreting YSOs with strong outflows. Finally, despite having sufficient sensitivity and resolution to detect high-velocity compact clouds (HVCCs), which have been claimed as evidence for intermediate mass black holes interacting with molecular gas clouds, we find no such objects across the large survey area.Comment: 44 pages, 41 figure

Experimental warming differentially affects vegetative and reproductive phenology of tundra plants

Rapid climate warming is altering Arctic and alpine tundra ecosystem structure and function, including shifts in plant phenology. While the advancement of green up and flowering are well-documented, it remains unclear whether all phenophases, particularly those later in the season, will shift in unison or respond divergently to warming. Here, we present the largest synthesis to our knowledge of experimental warming effects on tundra plant phenology from the International Tundra Experiment. We examine the effect of warming on a suite of season-wide plant phenophases. Results challenge the expectation that all phenophases will advance in unison to warming. Instead, we find that experimental warming caused: (1) larger phenological shifts in reproductive versus vegetative phenophases and (2) advanced reproductive phenophases and green up but delayed leaf senescence which translated to a lengthening of the growing season by approximately 3%. Patterns were consistent across sites, plant species and over time. The advancement of reproductive seasons and lengthening of growing seasons may have significant consequences for trophic interactions and ecosystem function across the tundra.publishedVersio

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Connectivity-based parcellation of the human frontal polar cortex

The frontal pole corresponds to Brodmann area (BA) 10, the largest single architectonic area in the human frontal lobe. Generally, BA10 is thought to contain two or three subregions that subserve broad functions such as multitasking, social cognition, attention, and episodic memory. However, there is a substantial debate about the functional and structural heterogeneity of this large frontal region. Previous connectivity-based parcellation studies have identified two or three subregions in the human frontal pole. Here, we used diffusion tensor imaging to assess structural connectivity of BA10 in 35 healthy subjects and delineated subregions based on this connectivity. This allowed us to determine the correspondence of structurally based subregions with the scheme previously defined functionally. Three subregions could be defined in each subject. However, these three subregions were not spatially consistent between subjects. Therefore, we accepted a solution with two subregions that encompassed the lateral and medial frontal pole. We then examined resting-state functional connectivity of the two subregions and found significant differences between their connectivities. The medial cluster was connected to nodes of the default-mode network, which is implicated in internally focused, self-related thought, and social cognition. The lateral cluster was connected to nodes of the executive control network, associated with directed attention and working memory. These findings support the concept that there are two major anatomical subregions of the frontal pole related to differences in functional connectivity