77 research outputs found

    Toward Energy Efficient Multiuser IRS-Assisted URLLC Systems: A Novel Rank Relaxation Method

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    This paper proposes an energy efficient resource allocation design algorithm for an intelligent reflecting surface (IRS)-assisted downlink ultra-reliable low-latency communication (URLLC) network. This setup features a multi-antenna base station (BS) transmitting data traffic to a group of URLLC users with short packet lengths. We maximize the total network's energy efficiency (EE) through the optimization of active beamformers at the BS and passive beamformers (a.k.a. phase shifts) at the IRS. The main non-convex problem is divided into two sub-problems. An alternating optimization (AO) approach is then used to solve the problem. Through the use of the successive convex approximation (SCA) with a novel iterative rank relaxation method, we construct a concave-convex objective function for each sub-problem. The first sub-problem is a fractional program that is solved using the Dinkelbach method and a penalty-based approach. The second sub-problem is then solved based on semi-definite programming (SDP) and the penalty-based approach. The iterative solution gradually approaches the rank-one for both the active beamforming and unit modulus IRS phase-shift sub-problems. Our results demonstrate the efficacy of the proposed solution compared to existing benchmarks

    Toxicity, and biological and biochemical effects of hexaflumuron on the elm leaf beetle, Xanthogaleruca luteola (Col.: Chrysomelidae)

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    The elm leaf beetle, Xanthogaleruca luteola Müll., is the most important pest of elm trees in Iranian cities. Insect growth regulators (IGRs) such as hexaflumuron are recommended to use in urban areas for their low toxicity to human and environment. In this study, the impact of the chitin synthesis inhibitor, hexaflumuron, was evaluated on some biochemical and biological characteristics of the elm leaf beetle under laboratory conditions. The toxicity of this insecticide investigated on the last instar larvae of X. luteola using leaf dip method (25 ± 2 ºC, 75 ± 10% relative humidity, 16 h (light): 8 h (dark)). LC30 and LC50 values were calculated at 53.45 and 122.02 ppm, 72 h post treatment, respectively. Biological and biochemical characteristics were evaluated for 3rd instar larvae, following 72 h feeding on the elm leaves treated with LC50 and LC30 concentrations of hexaflumuron. The LC30 and LC50 concentrations of hexaflumuron increased the duration of larval stage, 10.04 ± 0.24 and 9.27 ± 0.43 days, respectively, compared with the control, 7.07 ± 0.413 days. There were no significant differences in the duration of pupal stage for LC30 and LC50 concentrations and control group. Hexaflumuron significantly decreased adult longevity compared with the control. Several morphological abnormalities were also observed in treated larvae and pupae. The results showed significant reductions of carbohydrate, protein, glycogen and lipid contents at the LC30 and LC50 concentrations of hexaflumuron. The activities of the detoxifying enzyme glutathione S-transferase, general esterases (α-esterases and β-esterases) and the immunological enzyme phenoloxidase were significantly affected by hexaflumuron. Although the results are clearly indicative of the adverse effects of sublethal concentrations of hexaflumuron on the beetle pest, further investigations are required to improve the efficiency of the chemical for being viably used in integrated pest management programs against the elm leaf beetle

    SITE SELECTION TO HAZARDOUS WASTE LANDFILL OF GILANEGHARB TOWNSHIP IN KERMANSHAH PROVINCE, WESTERN IRAN BY USING REMOTE SENSING AND GIS

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    Each of them has different effects on site selection of hazardous waste landfill. Some factors cause limits to site selection such as; climatic, topographic, land use, edaphic, quakeable, regions under conservation of environment organization and so on. these factors may be cause unsustainable and move hazardous waste to surface and under ground water and also air pollution according to wind aspect, consequently different contaminations. This study was conducted in Gilanegharb town in Kermanshah province west of Iran in 2012 to find best area of landfill of hazardous wastes. Each of the factors valued and weighted based on experts opinions and then evaluated each of the preperated layers in RS and GIS softwares. In the first evaluation of 19 sites, 6 sites were investigated. The results show that asphalt factory site is the best region and then Shahrdary, Tan Kooshk sites are better to landfill of hazardous waste respectively. The reasons for selecting of this regions were far form surface and ground water resources and as a result avoiding to be defiled of ground water. On the other hand, there is no air pollution and malodorous of Ghilangharb town because of wind blow aspect in the region

    The Effects of Blade Configurations on Performance of a Tidal Vertical Axis Turbine

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    Hydrokinetic energy contains the major uncontrolled source of renewable marine energy. The highest level of converter technology readiness offered in the last three decades is TRL8–9, which is related to the first-generation horizontal axis converters. In low-depth calm waters, one of the best options to harvest tidal energy is vertical axis turbines. About 16% of the conceptual designs presented in the last 30 years apply this type of converter, which does not have a high level of technological readiness. In this study, a laboratory-designed vertical axis turbine has been introduced in which the effects of the number of blades, the blade profile, and attack angle on the performance of the turbine were analyzed. A 3D incompressible viscous turbulent computational finite volume approach is applied, with the spatial second-order and temporal first-order accuracies. The turbulent model k-ω SST was used to obtain the flow inside the turbine. Rotors include two, three, and six blades with three different profiles, including NACA2421, NACA16021, and NACA0020. Computational results reveal that the turbine with three blades and an angle of attack of +8 using the NACA2421 profile has a maximum generation capacity of about 4 kW, with a strength factor of 0.4 and a power factor of about 20%. The capacity, however, was lower for a higher number of blades

    Effect of Sweet Wormwood Artemisia annua Crude Leaf Extracts on Some Biological and Physiological Characteristics of the Lesser Mulberry Pyralid, Glyphodes pyloalis

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    The lesser mulberry pyralid, Glyphodes pyloalis Walker (Lepidoptera: Pyralidae) is a monophagous and dangerous pest of mulberry that has been recently observed in Guilan province, northern Iran. In this study, the crude methanol extract of sweet wormwood Artemisia annua L. (Asterales: Asteracaea) was investigated on toxicity, biological and physiological characteristics of this pest under controlled conditions (24 ± 1 °C, 75 ± 5% RH, and 16:8 L:D photoperiod). The effect of acute toxicity and sublethal doses on physiological characteristics was performed by topical application. The LC50 and LC20 values on fourth instar larvae were calculated as 0.33 and 0.22 gram leaf equivalent/ mL, respectively. The larval duration of fifth instar larvae in LC50 treatment was prolonged (5.8 ± 0.52 days) compared with the control group (4.26 ± 0.29 days). However larval duration was reduced in the LC20 treatment. The female adult longevity in the LC50 dose was the least (4.53 ± 0.3 days), while longevity among controls was the highest (9.2 ± 0.29 days). The mean fecundity of adults after larval treatment with LC50 was recorded as 105.6 ± 16.84 eggs/female, while the control was 392.74 ± 22.52 eggs/female. The percent hatchability was reduced in all treatments compared with the control. The effect of extract in 0.107, 0.053, 0.026 and 0.013 gle/mL on biochemical characteristics of this pest was also studied. The activity of α-amylase and protease 48 hours post—treatment was significantly reduced compared with the control. Similarly lipase, esterase, and glutathione S-transferase activity were significantly affected by A. annua extract

    Mapping 123 million neonatal, infant and child deaths between 2000 and 2017

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    Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2—to end preventable child deaths by 2030—we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000–2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained rates of 25 or fewer child deaths per 1,000 live births by 2017, and that 58% of child deaths between 2000 and 2017 in these countries could have been averted in the absence of geographical inequality. This study enables the identification of high-mortality clusters, patterns of progress and geographical inequalities to inform appropriate investments and implementations that will help to improve the health of all populations

    Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17

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    Background: Universal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease and improving human wellbeing. Comprehensive, high-resolution estimates are important to inform progress towards achieving this goal. We aimed to produce high-resolution geospatial estimates of access to drinking water and sanitation facilities. Methods: We used a Bayesian geostatistical model and data from 600 sources across more than 88 low-income and middle-income countries (LMICs) to estimate access to drinking water and sanitation facilities on continuous continent-wide surfaces from 2000 to 2017, and aggregated results to policy-relevant administrative units. We estimated mutually exclusive and collectively exhaustive subcategories of facilities for drinking water (piped water on or off premises, other improved facilities, unimproved, and surface water) and sanitation facilities (septic or sewer sanitation, other improved, unimproved, and open defecation) with use of ordinal regression. We also estimated the number of diarrhoeal deaths in children younger than 5 years attributed to unsafe facilities and estimated deaths that were averted by increased access to safe facilities in 2017, and analysed geographical inequality in access within LMICs. Findings: Across LMICs, access to both piped water and improved water overall increased between 2000 and 2017, with progress varying spatially. For piped water, the safest water facility type, access increased from 40·0% (95% uncertainty interval [UI] 39·4–40·7) to 50·3% (50·0–50·5), but was lowest in sub-Saharan Africa, where access to piped water was mostly concentrated in urban centres. Access to both sewer or septic sanitation and improved sanitation overall also increased across all LMICs during the study period. For sewer or septic sanitation, access was 46·3% (95% UI 46·1–46·5) in 2017, compared with 28·7% (28·5–29·0) in 2000. Although some units improved access to the safest drinking water or sanitation facilities since 2000, a large absolute number of people continued to not have access in several units with high access to such facilities (>80%) in 2017. More than 253 000 people did not have access to sewer or septic sanitation facilities in the city of Harare, Zimbabwe, despite 88·6% (95% UI 87·2–89·7) access overall. Many units were able to transition from the least safe facilities in 2000 to safe facilities by 2017; for units in which populations primarily practised open defecation in 2000, 686 (95% UI 664–711) of the 1830 (1797–1863) units transitioned to the use of improved sanitation. Geographical disparities in access to improved water across units decreased in 76·1% (95% UI 71·6–80·7) of countries from 2000 to 2017, and in 53·9% (50·6–59·6) of countries for access to improved sanitation, but remained evident subnationally in most countries in 2017. Interpretation: Our estimates, combined with geospatial trends in diarrhoeal burden, identify where efforts to increase access to safe drinking water and sanitation facilities are most needed. By highlighting areas with successful approaches or in need of targeted interventions, our estimates can enable precision public health to effectively progress towards universal access to safe water and sanitation

    Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019

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    Background: Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10–24 years during the past three decades. Methods: Using the Global Burden of Disease, Injuries, and Risk Factors 2019 Study, we analysed mortality and disability-adjusted life-years (DALYs) attributed to transport and unintentional injuries for adolescents in 204 countries. Burden is reported in absolute numbers and age-standardised rates per 100 000 population by sex, age group (10–14, 15–19, and 20–24 years), and sociodemographic index (SDI) with 95% uncertainty intervals (UIs). We report percentage changes in deaths and DALYs between 1990 and 2019. Findings: In 2019, 369 061 deaths (of which 214 337 [58%] were transport related) and 31·1 million DALYs (of which 16·2 million [52%] were transport related) among adolescents aged 10–24 years were caused by transport and unintentional injuries combined. If compared with other causes, transport and unintentional injuries combined accounted for 25% of deaths and 14% of DALYs in 2019, and showed little improvement from 1990 when such injuries accounted for 26% of adolescent deaths and 17% of adolescent DALYs. Throughout adolescence, transport and unintentional injury fatality rates increased by age group. The unintentional injury burden was higher among males than females for all injury types, except for injuries related to fire, heat, and hot substances, or to adverse effects of medical treatment. From 1990 to 2019, global mortality rates declined by 34·4% (from 17·5 to 11·5 per 100 000) for transport injuries, and by 47·7% (from 15·9 to 8·3 per 100 000) for unintentional injuries. However, in low-SDI nations the absolute number of deaths increased (by 80·5% to 42 774 for transport injuries and by 39·4% to 31 961 for unintentional injuries). In the high-SDI quintile in 2010–19, the rate per 100 000 of transport injury DALYs was reduced by 16·7%, from 838 in 2010 to 699 in 2019. This was a substantially slower pace of reduction compared with the 48·5% reduction between 1990 and 2010, from 1626 per 100 000 in 1990 to 838 per 100 000 in 2010. Between 2010 and 2019, the rate of unintentional injury DALYs per 100 000 also remained largely unchanged in high-SDI countries (555 in 2010 vs 554 in 2019; 0·2% reduction). The number and rate of adolescent deaths and DALYs owing to environmental heat and cold exposure increased for the high-SDI quintile during 2010–19. Interpretation: As other causes of mortality are addressed, inadequate progress in reducing transport and unintentional injury mortality as a proportion of adolescent deaths becomes apparent. The relative shift in the burden of injury from high-SDI countries to low and low–middle-SDI countries necessitates focused action, including global donor, government, and industry investment in injury prevention. The persisting burden of DALYs related to transport and unintentional injuries indicates a need to prioritise innovative measures for the primary prevention of adolescent injury. Funding: Bill & Melinda Gates Foundation

    Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

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    Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens
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