Narrativas de jovens adultos sobre os seus comportamentos autolesivos

Dissertação de Mestrado apresentada no ISPA – Instituto Universitário para a obtenção de grau de Mestre na especialidade de Psicologia Clínica.Jovens adultos encontram-se, frequentemente, em situações que prejudicam a sua saúde mental e, se estes problemas não forem tratados adequadamente, podem desenvolver-se problemas mais sérios, como comportamentos autolesivos. Os comportamentos autolesivos são comportamentos utilizados para causar dano ao próprio, constituindo manifestações de um mal-estar interno, contemplando comportamentos como os cortes ou as queimaduras. Sendo assim, torna-se importante permitir aos jovens que partilhem as suas experiências com estes comportamentos para serem compreendidos e receberem tratamento adequado. Neste sentido, esta investigação explora os conteúdos das narrativas dos jovens sobre os comportamentos autolesivos, abordando aspetos como o método utilizado, as motivações, as funções destes e as suas consequências. Este estudo contempla uma amostra de 32 jovens adultos, entre os 18 e os 21, que preencheram o Inventário de Comportamentos Autolesivos, incluindo questões que os permitiram partilhar narrativas. Os resultados da investigação mostram que os métodos mais referidos diferem entre o ICAL e as narrativas, mas com maior incidência sobre o bater-se e o cortar-se. São referidos diversos fatores que conduziram à autolesão, principalmente de caráter interno, como desejo de fugir da dor e emoções negativas, e as funções atribuídas a estes comportamentos, nomeadamente a função de fugir, de escape, e a de regulação emocional, contemplando consequências como a hospitalização. Finalmente, são sugeridas recomendações para investigações futuras, estando reconhecida a importância da intervenção psicológica para mitigar as consequências negativas destes comportamentos.Young adults are, frequently, faced with situations that harm their mental health and, if these problems aren’t adequately treated, more serious problems might develop, such as self-harming behaviors. Self-harming behaviors are behaviors used to cause harm to oneself, working as manifestations of internal distress, including behaviors such as cutting or burning one’s body. Therefore, it’s important to allow these young adults to share their experiences with these behaviors so that they can be understood and receive proper care and treatment. Thus, this investigation explores the contents of their stories about their self-harming behaviors, focusing on aspects like the methods they use, their motivations, the functions of these behaviors, and their consequences. This study followed a sample of 32 young adults, with ages between 18 and 21, who filled out the Inventory of Self-Harming Behaviors, including questions that allowed them to share their stories. The results showed that the most referred to methods differ between the questionnaire and the narratives, but the most prevalent ones across both parts of the instrument are hitting oneself and cutting. There are multiple factors that led to the self-harm, especially those of internal nature, like the desire to escape and as an attempt of regulating one’s emotions, facing consequences like hospitalization. Finally, some recommendations for future investigations are suggested, acknowledging just how important a psychological intervention is to lower and prevent the negative consequences of these behaviors

Propiedades psicométricas del Pain and Sensitivity Reactivity Scales (PSRS) en población neurotípica infantojuvenil

La percepción del dolor y la reactividad sensorial se presenta como una tarea difícil para la ciencia al ser considera una respuesta subjetiva que depende de diferencias individuales. Esta dificultad se incrementa aún más si la población de estudio incluye a niños y a adolescentes. Para la medición de esta respuesta se pueden utilizar medidas neurofisiológicas o escalas estandarizadas que cuantifiquen la información. Esta evaluación es de suma importancia, ya que puede detectar si existe una dificultad para recibir e interpretar los estímulos sensoriales tanto exteroceptivos como interoceptivos. Sin embargo, aún no existe una escala dimensional para población infanto-juvenil que aborde este campo. El objetivo de este estudio es presentar las propiedades psicométricas del Pain and Sensitivity Reactivity Scale (PSRS) en población infanto-juvenil neurotípica. La muestra está formada por más de 1000 niños y adolescentes de 12 a 17 años. La versión infanto-juvenil de la PSRS está formada tres escalas que hacen referencia al dolor, la hiposensibilidad e hipersensibilidad. Los resultados muestran una consistencia interna adecuada tanto para las diferentes escalas y como para el instrumento. Por último, en el análisis factorial exploratorio aparecen las tres dimensiones principales. En conclusión, poder evaluar la percepción del dolor y la reactividad sensorial en población infanto-juvenil puede ayudar a contextualizar problemas conductuales, emocionales e incluso académicos que pueden estar encubiertos por el desconocimiento que tanto el propio individuo muestra sobre su percepción como por el desconocimiento que familiares y profesionales de la educación presentan sobre las diferencias en la reactividad sensorial y la percepción del dolor.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

Prevalence and dietetic management of mild gastrointestinal disorders in milk-fed infants

AIM: To assess the prevalence of mild gastrointestinal disorders in milk-fed infants in paediatric practice, and to evaluate the effectiveness and satisfaction with dietetic treatment