97 research outputs found
Epigenetic and post-transcriptional regulation of somatostatin receptor subtype 5 (SST5 ) in pituitary and pancreatic neuroendocrine tumors.
- Author
- Publication venue
- 'Wiley'
- Publication date
- 03/10/2021
- Field of study
Somatostatin receptor subtype 5 (SST5 ) is an emerging biomarker and actionable target in pituitary (PitNETs) and pancreatic (PanNETs) neuroendocrine tumors. Transcriptional and epigenetic regulation of SSTR5 gene expression and mRNA biogenesis is poorly understood. Recently, an overlapping natural antisense transcript, SSTR5-AS1, potentially regulating SSTR5 expression, was identified. We aimed to elucidate whether epigenetic processes contribute to the regulation of SSTR5 expression in PitNETs (somatotropinomas) and PanNETs. We analyzed the SSTR5/SSTR5-AS1 human locus in silico to identify CpG islands. SSTR5 and SSTR5-AS1 expression was assessed by quantitative real-time PCR (qPCR) in 27 somatotropinomas, 11 normal pituitaries (NPs), and 15 PanNETs/paired adjacent (control) samples. We evaluated methylation grade in four CpG islands in the SSTR5/SSTR5-AS1 genes. Results revealed that SSTR5 and SSTR5-AS1 were directly correlated in NP, somatotropinoma and PanNET samples. Interestingly, selected CpG islands were differentially methylated in somatotropinomas compared with NPs. In PanNETs cell lines, SSTR5-AS1 silencing downregulated SSTR5 expression, altered aggressiveness features, and influenced pasireotide response. These results provide evidence that SSTR5 expression in PitNETs and PanNETs can be epigenetically regulated by the SSTR5-AS1 antisense transcript and, indirectly, by DNA methylation, which may thereby impact tumor behavior and treatment response
Expansion of Signal Transduction Pathways in Fungi by Extensive Genome Duplication
- Author
- Avalos Javier
- Baker Scott E.
- Bauer Diane
- Benoit Isabelle
- Braun Edward L.
- Burger Gertraud
- Camino Lola P.
- CerdĂĄ-Olmedo Enrique
- Cheng Jan-Fang
- Corrochano Luis M.
- CĂĄnovas David
- de Vries Ronald P.
- DomĂnguez Angel
- EliĂĄĆĄ Marek
- GabaldĂłn Toni
- Garre Victoriano
- Glaser Fabian
- Grigoriev Igor V.
- Grimwood Jane
- Gutiérrez Gabriel
- Heitman Joseph
- Henrissat Bernard
- Herrera-Estrella Alfredo
- Horwitz Benjamin A.
- Idnurm Alexander
- Iturriaga Urbistondo Enrique Alejandro
- Kuo Alan
- Lang B. Franz
- LavĂn JosĂ©Â L.
- Lee Soo Chan
- Li Wenjun
- Lindquist Erika
- Luque Eva M.
- LĂłpez-GarcĂa Sergio
- Marcet-Houben Marina
- Marcos Ana T.
- Martin Joel
- McCluskey Kevin
- Medina Humberto R.
- Miralles-DurĂĄn Alejandro
- Miyazaki Atsushi
- Muñoz-Torres Elisa
- Oguiza José A.
- Ohm Robin A.
- Olmedo MarĂa
- Orejas Margarita
- Ortiz-Castellanos Lucila
- Pisabarro Antonio G.
- Polaino Silvia
- PĂ©rez Benito Ernesto
- PĂ©rez Eslava Arturo
- RodrĂguez-Romero Julio
- Ruiz-Herrera José
- Ruiz-VĂĄzquez Rosa
- Salamov Asaf
- Sanz Catalina
- Schackwitz Wendy
- Schmutz Jeremy
- Shahriari Mahdi
- Shelest Ekaterina
- Silva-Franco FĂĄtima
- Soanes Darren
- Syed Khajamohiddin
- Tagua VĂctor G.
- Talbot Nicholas J.
- Thon Michael R.
- Tice Hope
- Torres-MartĂnez Santiago
- Villalobos-Escobedo José M.
- Wiebenga Ad
- Yadav Jagjit S.
- Ălvarez M. Isabel
- Publication venue
- Elsevier
- Publication date
- 20/06/2016
- Field of study
[EN] Plants and fungi use light and other signals to regulate development, growth, and metabolism. The fruiting bodies of the fungus Phycomyces blakesleeanus are single cells that react to environmental cues, including light, but the mechanisms are largely unknown [1]. The related fungus Mucor circinelloides is an opportunistic human pathogen that changes its mode of growth upon receipt of signals from the environment to facilitate pathogenesis [2]. Understanding how these organisms respond to environmental cues should provide insights into the mechanisms of sensory perception and signal transduction by a single eukaryotic cell, and their role in pathogenesis. We sequenced the genomes of P. blakesleeanus and M. circinelloides and show that they have been shaped by an extensive genome duplication or, most likely, a whole-genome duplication (WGD), which is rarely observed in fungi [3-6]. We show that the genome duplication has expanded gene families, including those involved in signal transduction, and that duplicated genes have specialized, as evidenced by differences in their regulation by light. The transcriptional response to light varies with the developmental stage and is still observed in a photoreceptor mutant of P. blakesleeanus. A phototropic mutant of P. blakesleeanus with a heterozygous mutation in the photoreceptor gene madA demonstrates that photosensor dosage is important for the magnitude of signal transduction. We conclude that the genome duplication provided the means to improve signal transduction for enhanced perception of environmental signals. Our results will help to understand the role of genome dynamics in the evolution of sensory perception in eukaryotes.European funds (European Regional Development Fund, ERDF); Spanish Ministerio de EconomıŽa y Competitividad; Junta de AndalucĂ
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
- Author
- Abbott TE
- Abdallah RI
- Abdel-Aal IR
- Abdelmonem SA
- Abdo WF
- Abellan AN
- AbellĂĄn AN
- AbellĂĄn AN
- AbellĂĄn AN
- Abrams ST
- Ackerley C
- Acuña M
- Adda M
- Adhikari NK
- Adriano G
- Adrie C
- Affatato R
- Affatato R
- Afonso-Rivero D
- Agarossi A
- Agarwal LK
- Ageeva T
- Agrawal R
- Aguayo-DeHoyos E
- Aguilar AL
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguirregabyria M
- Ahmadnia E
- Ahn C
- Ahn JY
- Ahn JY
- Ahn MY
- Ahn MY
- Aitken LM
- Akalaev R
- Akbarzadeh A
- Akcan-Arikan A
- Akhlagh SH
- Akhtar N
- AKI Research Group
- Akiduki N
- Akin S
- Akizuki N
- Akkoc T
- Ala-Kokko T
- Alanio A
- Albaiceta GM
- Albaladejo P
- Alberto F
- Albuisson E
- Alcala MA
- AlcĂĄzar L
- Aldabo-Pallas T
- Aldana NN
- Aldecoa C
- AlegrĂa L
- Alejandro R
- Alejo GC
- Alejos RM
- Alexandrova E
- Algarte R
- Algarte R
- Algieri I
- Algora-Weber A
- Alhamdi Y
- Aliaga FA
- Aliberti S
- Alkan A
- Almudena PM
- Almudevar PM
- Almudevar PM
- Almudévar PM
- Altıntas ND
- Alvarez J
- Alves SC
- Alzola LM
- Amargianitakis V
- Amaro R
- Amato MB
- Ambler M
- Amerongen MP
- Amininejad T
- Amor LL
- Amorim V
- Anand RK
- Andersen LW
- Andersson S
- Andoh K
- Andrade AH
- Andrade AH
- Andrade AH
- Andrade G
- Andreis DT
- Andreis DT
- Annane D
- Antonelli M
- Antoniadou A
- Antonio C
- Antonucci E
- AntĂłn DG
- Anzueto A
- Appiani F
- Aquevedo A
- Aragon C
- Araujo NJ
- Araujo VF
- ARIAM registry of adult cardiac surgery
- ARIAM-ANDALUCIA
- Arias CC
- Arias N
- Arias-Verdu MD
- Arias-Verdu MD
- Arias-Verdu MD
- Armaganidis A
- Arora MK
- Arora N
- Arrigo M
- Arslantas MK
- Artiguenave M
- Aslanian P
- Aspide R
- Asyralyyeva G
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- Athapattu P
- Atkins G
- Aublanc M
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- Avramidis V
- Ayala LY
- Aydin M
- Azevedo JC
- Azevedo JR
- Aznar GP
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- Bachli EB
- Bader A
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- Barcenilla F
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- Chemam S
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- Cheng CC
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- Chernyshuk S
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- Chhor V
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- Chiang CH
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- Chiappa C
- Chiou KR
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- Chiu LC
- Chiumello D
- Chiurazzi C
- Chiurazzi C
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- Choi JY
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- Cholley B
- Chondropoulos S
- Chou W
- Chouris I
- Chouvarda I
- Christopher KB
- Chrétien JM
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- Chumaev A
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- Cinnella G
- Citerio G
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- Clermont G
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- De Brito-Ashurst I
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- Dilly MP
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- Dimitroulakis K
- Dimitrov BD
- Dimitrov BD
- Dimopoulou IK
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- Divatia JV
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- ENVIN-HELICS Study Group
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- Fernandez-Zamora MD
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- Filho CA
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- Filipe E
- FINNRESUSCI Study Group
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- FROG ICU Investigators
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- Hempel D
- Henderson MA
- Hendra H
- Henschel B
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- HernĂĄndez A
- HernĂĄndez AA
- HernĂĄndez AA
- HernĂĄndez AA
- HernĂĄndez AA
- HernĂĄndez AA
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- HernĂĄndez G
- HernĂĄndez-Tejedor A
- Herpain A
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- Herrera AN
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- Hillier SD
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- Hodgson LE
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- Hraiech S
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- Hua Y
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- Hualde JB
- Hualde JB
- Hualde JB
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- Huang CH
- Huang WC
- Huang WC
- Huang WC
- Huang WC
- Hubbard A
- Huber W
- Huddart S
- Hull AM
- Hung CY
- Hung WT
- Hung WT
- Hung WT
- Hung WT
- Huot B
- Husheer SL
- Hutchings S
- Hutchison R
- Hwang GS
- Hwang GS
- Ibañes PG
- Ibsen M
- Idei M
- Idei M
- Idone FA
- Iesu E
- Iesu E
- Iglesias-Santiago A
- Ignacio ML
- Iida A
- Iijima H
- Ilan R
- Ilyina V
- Imanaka H
- Inaloo S
- Ince C
- Iotti GA
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- IPREA Study Group
- Irazabal JM
- Irazabal JM
- Ishimatsu S
- Itenov TS
- Iwamoto M
- Izawa M
- Izdes S
- Jaber S
- Jacky A
- Jacobs FM
- Jacques T
- Jaffal K
- Jamali S
- Jang BH
- Janotka M
- Janotka M
- Janotka M
- Jansen D
- Jansen N
- Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group
- Jardim JJ
- Jardim M
- Jareño A
- Javadpour S
- Jayasinghe S
- Jean-Baptiste S
- Jean-Baptiste S
- Jensen AE
- Jensen JU
- Jeon YD
- Jeon YD
- Jeong IY
- Jeong IY
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- Jian Z
- Jiao LR
- Jibaja M
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- Jiménez GJ
- Jo YH
- Joachim J
- Jochmans S
- John G
- Jonas M
- Jonas M
- Jonas M
- Jones C
- Joshi R
- Joshi V
- Jovaisa T
- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
- Juan WC
- Juanas CA
- Judickas S
- Juez A
- Juliarena A
- Jun IG
- Jun IG
- Jung K
- Jung KW
- Junior JM
- Kaczirek K
- Kaese S
- Kalani N
- Kalenka A
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- Kamali E
- Kaminsky GE
- Kaneko M
- Kang M
- Kang M
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- Kang PL
- Kang PL
- Kang PL
- Kang Y
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- Kappler F
- Kara A
- Karachi F
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- Karbing DS
- Karsten E
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- Kashiya S
- Kashyap R
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- Katabami K
- Katabami K
- Katabami K
- Katira BH
- Kavanagh BP
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- Kim DJ
- Kim HJ
- Kim JM
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- Kim JW
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- Kim KS
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- Kim KS
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- Kim MH
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- Kleinpell R
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- Knight LD
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- Ko SB
- Kobayashi A
- Koco E
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- Kodate A
- Kodate A
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- Kolnikova I
- Komuro T
- Kondili E
- Kongpolprom N
- Kooner G
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- Kosuk ME
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- Kou PS
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- Kox M
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- Krenn CG
- Krishna B
- Kristof J
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- Kumari BK
- Kumbamu A
- Kunze-Szikszay N
- Kurmukov IA
- Kurth T
- Kurtz P
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- Kwon HM
- Kwon WY
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- Labra C
- Lacerda P
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- Lafuente E
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- Lagos R
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- Latini R
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- PICS- HCPA: Programa Intrahospitalar de Combate Ă Sepse do Hospital de ClĂnicas de Porto Alegre
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- St Georgeâs University of London
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- Student Research Committee - Shiraz University of Medical Sciences
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- Tokyo Womens Medical University
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- WIND study group
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- WIND study group
- Winder-Rhodes S
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- Yılmaz G
- Yilmazer F
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- Yonis H
- Yonis H
- Yoon SZ
- Yoruk F
- Yoshida K
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- Yoshida T
- Yoshida T
- Yoshida T
- Yoshihiro S
- Yoshitake E
- You KM
- Youn AM
- Young A
- Yu KM
- Yumoto T
- Yuzawa J
- Yuzawa J
- Zabaletta WJ
- Zabini D
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- Zaien I
- Zakynthinos S
- Zanello M
- Zani D
- Zarantonello F
- Zayas B
- Zepeda EM
- Zeroual N
- Zerva L
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- Zhou JC
- Zhou JC
- Zhou JX
- Zhovnir V
- Zibandah N
- Zijlstra F
- Zimmerman J
- Zogheib E
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- Zogheib E
- Zullino V
- Zwaag J
- ZĂœkovĂĄ I
- Ălvarez JT
- Ălvarez-Lerma F
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
Search for dark matter produced in association with a Higgs boson decaying to a pair of bottom quarks in proton-proton collisions at root s=13TeV
- Author
- Aarrestad TK
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullah WATW
- Abdullin S
- Abercrombie D
- Acharya H
- Acosta D
- Acosta JG
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- Adloff C
- Adzic P
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- Afanasiev S
- Agapitos A
- Agarwal G
- Aggleton R
- Agram J-L
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- Ahmad A
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- Ahmad WH
- Ahmed A
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- Alonso AG
- Alvarez JDR
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- Amaral SMSD
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- Anampa KH
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- Andreev V
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- Asavapibhop B
- Asawatangtrakuldee C
- Asenov P
- Asghar MI
- Asilar E
- Askew A
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- Atakisi IO
- Atanasov I
- Ather MW
- Attikis A
- Auffray E
- Aushev T
- Auzinger G
- Avati V
- Avery P
- Avila C
- Awan MIM
- Ayala E
- Ayala G
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzurri P
- Baarmand MM
- Babaev A
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- Bacchetta N
- Bachiller I
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- Bagliesi G
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- Baillon P
- Bainbridge R
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- Banerjee S
- Banerjee S
- Banos LIE
- Bansal S
- Barbagli G
- Barberis E
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- Baringer P
- Barnes VE
- Barney D
- Baron O
- Barrera CB
- Barrera CO
- Bartek R
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- Battilana C
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- Bianchini L
- Bianco M
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- Biasini M
- Bihan A-CL
- Biino C
- Bilei GM
- Bilin B
- Bindhu VKMN
- Bisello D
- Black K
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- Butler JN
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- Bylinkin A
- Bylsma B
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- Caballero IG
- Cabrera A
- Cabrillo IJ
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- Cakir A
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- Cavallo FR
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- Cavanaugh R
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- Ceballos GG
- Ceccarelli R
- Cepaitis V
- Cepeda M
- Cerati GB
- Cerci DS
- Cerci S
- Cerminara G
- Cerrada M
- Cerri O
- Cetorelli F
- Chabert EC
- Chagas EBBD
- Chahal GS
- Chang P
- Chang P
- Chanon N
- Chao Y
- Chapon E
- Charaf O
- Charlot C
- Chatterjee RM
- Chatterjee S
- Chauhan S
- Chauhan S
- Chawla R
- Checchia P
- Chekhovsky V
- Chen C
- Chen GM
- Chen HS
- Chen KF
- Chen M
- Chen PH
- Chen X
- Chen Y
- Chen Y
- Chen Z
- Chenarani S
- Cheng T
- Cheng Y
- Cherepanov V
- Chernyavskaya N
- Chertok M
- Cheung HWK
- Chhibra SS
- Chiarito B
- Chinellato J
- Chistov R
- Chlebana F
- Cho S
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- Choi Y
- Chou JP
- Choudhary BC
- Choudhury S
- Chowdhury SR
- Chu J
- Chudasama R
- Chwalek T
- Ciangottini D
- Cifuentes JAB
- Ciocci MA
- Cipriani M
- Ciriolo V
- Cirkovic P
- Citron M
- Cittolin S
- Ciulli V
- Civinini C
- Claes DR
- Clare R
- Clement E
- Clerbaux B
- CMS Collaboration
- Cockerill DJA
- Coelho E
- Colaleo A
- Cole JE
- Colino N
- Collard C
- Colling D
- Cometti S
- Connor P
- Contardo D
- Conway J
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- Cooper SI
- Cooperstein S
- Corcodilos L
- Cornelis T
- Cortezon EP
- Cosby C
- Cossutti F
- Costa M
- Costa S
- Coubez X
- Couderc F
- Cousins R
- Covarelli R
- Cox B
- Cox PT
- Cranshaw DJ
- Creanza D
- Cremonesi M
- Cristella L
- Croce DD
- Cruz SS
- Csanad M
- Csorgo T
- Cuevas J
- Cuffiani M
- Cumalat JP
- Cummings G
- Cussans D
- Cutts D
- Czellar S
- D'Alessandro R
- D'Alfonso M
- D'Enterria D
- D'Hondt J
- Da Costa EM
- Da Rold A
- Da Silva De Araujo FT
- Da Silveira GG
- Dabrowski A
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- Dalchenko M
- Dallavalle GM
- Damarseckin S
- Damgov J
- Damiani DD
- Danilov M
- Danilov V
- Daponte V
- Darwish MR
- Das P
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- Dasgupta A
- Dash D
- Daskalakis G
- Dasu S
- Datta A
- Dauncey P
- David A
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- Davies G
- Davignon O
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- De Bruyn I
- De Cassagnac RG
- De Castro Manzano P
- De Clercq J
- De Cosa A
- De Fatis TT
- De Filippis N
- De Guio F
- De Iorio A
- De Jesus Damiao D
- De Klundert MV
- De La Barca Sanchez MC
- De La Cruz B
- De La Cruz-Burelo E
- De Lentdecker G
- De Leo K
- De Monchenault GH
- De Oliveira ACA
- De Palma M
- De Roeck A
- De Souza SF
- De TrocĂłniz JF
- De Wit A
- De Wolf EA
- Deelen N
- Defranchis MM
- Deile M
- Dejardin M
- Delaere C
- Delannoy AG
- Delcourt M
- Delgado A
- Delgado MAS
- Dell'Orso R
- Demaria N
- Demina R
- Demiragli Z
- Demiroglu ZS
- Denegri D
- Depasse P
- Dermenev A
- Dev N
- Dewanjee RK
- Dezoort G
- Dharmaratna WGD
- Dhingra N
- Diab B
- Diamantopoulou M
- Diaz D
- Didukh L
- Diemoz M
- Dierlamm A
- Dildick S
- Dilsiz K
- Dimitrov A
- Dimova T
- Dinardo ME
- Dini P
- Diotalevi T
- Dissertori G
- Dittmann J
- Dittmar M
- Dittmer S
- Dobson M
- Dobur D
- Dogra S
- Dolek F
- Dolen J
- Domenico MRD
- Dominguez A
- Donato S
- Donckt MV
- DonegĂ M
- Donertas IS
- Doninck WV
- Dordevic M
- Dorfer C
- Dorigo T
- Dorney B
- Doroba K
- Dorsett A
- Dozen C
- Dragicevic M
- Dremin I
- Dreyer T
- Droll A
- Duarte J
- Dube S
- Dubinin M
- Dudko L
- Dugad S
- Duh YT
- Dulemba JL
- Dumanoglu I
- Dupont N
- Durgut S
- Duric S
- Durkin LS
- Dutta D
- Dutta I
- Dutta S
- Dutta V
- Dziwok C
- DĂŒnser M
- Ebrahimi A
- Eckerlin G
- Ecklund KM
- Eckstein D
- Eerola P
- Ehataht K
- Eich M
- Eichhorn T
- Elgammal S
- Eliseev D
- Elkafrawy T
- Elliott-Peisert A
- Ellis KV
- Elmer P
- Elmetenawee W
- Elvira VD
- Eminizer M
- Emriskova N
- Eno SC
- Epshteyn V
- Erbacher R
- Erdmann M
- Erdmann W
- Erice C
- Erodotou E
- Errico F
- Ershov A
- Erö J
- Eskut E
- Espinosa TAG
- Estrada CU
- Etesami SM
- Eusebi R
- Evangelou I
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- Eysermans J
- Fabbri F
- Fabozzi F
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- Fallavollita F
- Fallon C
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- Faltermann N
- Fanfani A
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- Fasanella D
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- Ăzçelik Ă
- Publication venue
- Publication date
- 01/01/2018
- Field of study
A search for dark matter produced in association with a Higgs boson decaying to a pair of bottom quarks is performed in proton-proton collisions at a center-of-mass energy of 13 TeV collected with the CMS detector at the LHC. The analyzed data sample corresponds to an integrated luminosity of 35.9 fb(-1). The signal is characterized by a large missing transverse momentum recoiling against a bottom quark-antiquark system that has a large Lorentz boost. The number of events observed in the data is consistent with the standard model background prediction. Results are interpreted in terms of limits both on parameters of the type-2 two-Higgs doublet model extended by an additional light pseudoscalar boson a (2HDM+a) and on parameters of a baryonic Z simplified model. The 2HDM+a model is tested experimentally for the first time. For the baryonic Z model, the presented results constitute the most stringent constraints to date.Peer reviewe
A Deep Neural Network for Simultaneous Estimation of b Jet Energy and Resolution
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- Ăzçelik Ă
- Publication venue
- Publication date
- 01/01/2020
- Field of study
We describe a method to obtain point and dispersion estimates for the energies of jets arising from b quarks produced in proton-proton collisions at an energy of s = 13 TeV at the CERN LHC. The algorithm is trained on a large sample of simulated b jets and validated on data recorded by the CMS detector in 2017 corresponding to an integrated luminosity of 41 fb - 1 . A multivariate regression algorithm based on a deep feed-forward neural network employs jet composition and shape information, and the properties of reconstructed secondary vertices associated with the jet. The results of the algorithm are used to improve the sensitivity of analyses that make use of b jets in the final state, such as the observation of Higgs boson decay to b b ÂŻ
Search for Higgs Boson Pair Production in the Four b Quark Final State in Proton-Proton Collisions at root s=13 TeV
- Author
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- Zuo X
- Zuolo D
- Zygala L
- Ălvarez CR
- Ăzçelik Ă
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Search for invisible decays of the Higgs boson produced via vector boson fusion in proton-proton collisions at root s=13 TeV
- Author
- Aarrestad T
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdelalim A
- Abdullin S
- Abercrombie D
- Abreu A
- Acharya H
- Acosta D
- Acosta HE
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- Yao Y
- Yarar H
- Yates B
- Yazgan E
- Ye Z
- Yetkin E
- Yi K
- Yigitbasi E
- Yohay R
- Yoo H
- Yoo J
- Yoon I
- You Z
- Yu D
- Yu G
- Yu I
- Yu Pr
- Yu S
- Yuan L
- Yuan S
- Yuldashev B
- Yumiceva F
- Yzquierdo AP
- Zabi A
- Zacharopoulou A
- Zahid S
- Zaleski S
- Zalewski P
- Zanetti M
- Zarubin A
- Zarucki M
- Zecchinelli A
- Zeinali M
- Zeuner W
- Zghiche A
- Zhang F
- Zhang H
- Zhang J
- Zhang L
- Zhang W
- Zhang Y
- Zhang Z
- Zhao J
- Zhizhin I
- Zhokin A
- Zhu R
- Ziemons T
- Zipper N
- Zoi I
- Zolkapli Z
- Zorbakir I
- Zorbilmez C
- Zotto P
- Zotz A
- Zou D
- Zou R
- Zucchetta A
- Zumerle G
- Zuo X
- Zuolo D
- Zygala L
- Ălvarez CR
- Ăzçelik Ă
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Metaplastic breast cancer: a comparison between the most common histologies with poor immunohistochemistry factors
- Author
- A Luini
- AD Al Sayed
- B Weigelta
- C Villarreal-Garza
- Carlos PĂ©rez-Plasencia
- CM Pezzi
- D Rayson
- David CantĂș de LeĂłn
- Delia PĂ©rez-Montiel
- E Montagna
- EA Rakha
- Ernesto Soto-Reyes
- ES Wargotz
- ES Wargotz
- ES Wargotz
- ES Wargotz
- ES Wargotz
- FA Tavassoli
- G Dave
- G Paul Wright
- GM Tse
- GR Gibson
- H Lee
- HS Park
- HW Lai
- IC Chen
- JA Gilbert
- JA Harvey
- Jaime Coronel-MartĂnez
- JD Beatty
- JF Catroppo
- JM Park
- Luis Alonso Herrera-Montalvo
- R Yamaguchi
- Rafael VĂĄzquez-Romo
- RL Theriault
- Salim Abraham Barquet-Muñoz
- Silvia Patricia Villarreal-Colin
- SY Bae
- SY Jung
- TA Vela-ChĂĄvez
- TC Chao
- WA Mourad
- WH Tseng
- Y Song
- Y-S Lu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Multi-wavelength characterization of the blazar S5~0716+714 during an unprecedented outburst phase
- Author
- Acosta MV
- Agudo I
- Ahnen ML
- Almeida UBD
- Angelakis E
- Angelis AD
- Ansoldi S
- Antonelli LA
- Arcaro C
- Baack D
- BabiÄ A
- Banerjee B
- Bangale P
- Barrio JA
- Bastieri D
- Bednarek W
- Bernardini E
- Berse RC
- Berti A
- Bhattacharyya W
- Biland A
- Blanch O
- Bonnoli G
- Borman GA
- Carosi A
- Carosi R
- Casadio C
- Ceribella G
- Chatterjee A
- Colak SM
- Colin P
- Collaboration FTF-L
- Collaboration MAGIC
- Collaborators MWL
- Colombo E
- Contreras JL
- Cortina J
- Covino S
- Cumani P
- Dazzi F
- Delfino M
- Delgado J
- DomĂnguez A
- Dorner D
- Doro M
- Einecke S
- Elsaesser D
- FernĂĄndez-Barral A
- Fidalgo D
- Fonseca MV
- Font L
- Fruck C
- Galindo D
- Gallozzi S
- Garcia JR
- Garczarczyk M
- Gasparrini D
- Gaug M
- Giammaria P
- GodinoviÄ N
- GonzĂĄlez JB
- Gora D
- Grishina TS
- Guberman D
- Gurwell M
- Hadasch D
- Hahn A
- Hassan T
- Hayashida M
- Herrera J
- Hose J
- Hovatta T
- Hrupec D
- Ishio K
- Itoh R
- Jermak H
- Jorstad S
- JÀrvelÀ E
- Konno Y
- Kopatskaya EN
- Kraus A
- Krichbaum TP
- Kubo H
- Kuin NPM
- Kushida J
- KuveĆŸdiÄ D
- Larionov VM
- Larionova LV
- Lelas D
- Lien AY
- Lindfors E
- Lombardi S
- Longo F
- Lott B
- Lotto BD
- LÀhteenmÀki A
- LĂłpez M
- LĂłpez RJG
- Madejski G
- Maggio C
- Majumdar P
- Makariev M
- Maneva G
- Manganaro M
- Mannheim K
- Maraschi L
- Mariotti M
- Marscher A
- MartĂnez M
- Masuda S
- Max-Moerbeck W
- Mazin D
- Mielke K
- Minev M
- Miranda JM
- Mirzoyan R
- Molina SN
- Moralejo A
- Moreno V
- Moretti E
- Moroni PGP
- Morozova DA
- Myserlis I
- Nagayoshi T
- Nalewajko K
- Neustroev V
- Niedzwiecki A
- Nigro C
- Nilsson K
- Ninci D
- Nishijima K
- Noda K
- Nogués L
- Paiano S
- Palacio J
- Paneque D
- Paoletti R
- Paredes JM
- Pearson TJ
- Pedaletti G
- Peresano M
- Persic M
- Pierro FD
- Prandini E
- Prester DD
- Puljak I
- Ramakrishnan V
- Ramazani VF
- Rani B
- Readhead ACS
- Reeves RA
- Reichardt I
- Rhode W
- RibĂł M
- Rico J
- Righi C
- Rosillo MN
- Rugliancich A
- Saito T
- Satalecka K
- Savchenko SS
- Schweizer T
- Sitarek J
- Sobczynska D
- Stamerra A
- Steele IA
- Strzys M
- SuriÄ T
- Takahashi M
- Takalo L
- Tavecchio F
- Temnikov P
- TerziÄ T
- Teshima M
- Thompson DJ
- Tornikoski M
- Torres-AlbĂ N
- Treves A
- Troitskaya YV
- Troitsky I
- Tsujimoto S
- Vanzo G
- Vasilyev AA
- Vela PD
- Vovk I
- Ward JE
- Will M
- ZariÄ D
- Zensus JA
- Ć nidariÄ I
- Publication venue
- 'EDP Sciences'
- Publication date
- 01/01/2018
- Field of study
The BL Lac object S5~0716+714, a highly variable blazar, underwent an impressive outburst in January 2015 (Phase A), followed by minor activity in February (Phase B). The MAGIC observations were triggered by the optical flux observed in Phase A, corresponding to the brightest ever reported state of the source in the R-band. The comprehensive dataset collected is investigated in order to shed light on the mechanism of the broadband emission. Multi-wavelength light curves have been studied together with the broadband Spectral Energy Distributions (SEDs). The data set collected spans from radio, optical photometry and polarimetry, X-ray, high-energy (HE, 0.1 GeV 100 GeV) with MAGIC. The flaring state of Phase A was detected in all the energy bands, providing for the first time a multi-wavelength sample of simultaneous data from the radio band to the VHE. In the constructed SED the \textit{Swift}-XRT+\textit{NuSTAR} data constrain the transition between the synchrotron and inverse Compton components very accurately, while the second peak is constrained from 0.1~GeV to 600~GeV by \textit{Fermi}+MAGIC data. The broadband SED cannot be described with a one-zone synchrotron self-Compton model as it severely underestimates the optical flux in order to reproduce the X-ray to Îł-ray data. Instead we use a two-zone model. The EVPA shows an unprecedented fast rotation. An estimation of the redshift of the source by combined HE and VHE data provides a value of z=0.31±0.02statsâ±0.05sysâ, confirming the literature value. The data show the VHE emission originating in the entrance and exit of a superluminal knot in and out a recollimation shock in the inner jet. A shock-shock interaction in the jet seems responsible for the observed flares and EVPA swing. This scenario is also consistent with the SED modelling
Observation of triple J/Ï meson production in proton-proton collisions
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- Aarrestad TK
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdelalim AA
- Abdullah WATW
- Abdullin S
- Abercrombie D
- Abreu A
- Acharya H
- Acosta D
- Adam W
- Adamidis K
- Adams E
- Adams MR
- Adams T
- Addesa FM
- Adloff C
- Adzic P
- AdĂĄn DP
- Afanasiev S
- Agapitos A
- Agarwal G
- Aggleton R
- Agram J-L
- Aguilar-Benitez M
- Ahmad A
- Ahmad M
- Ahmad WH
- Ahmed A
- Ahuja S
- AimĂš C
- Akchurin N
- Akgun B
- Akpinar A
- Albergo S
- Albert A
- Albrecht S
- Albrow M
- Aleksandrov A
- Alexander J
- Alhusseini M
- Alimena J
- Alison J
- Almond J
- Alonso AG
- Alpana K
- Alvarez JDR
- Alverson G
- Alves GA
- Aly R
- Alyari M
- Amapane N
- Amarilo KM
- Ambrozas M
- Amendola C
- Amin N
- Amram O
- Amsler C
- An S
- An Y
- Anagnostou G
- Anampa KH
- Andrea J
- Andreassi G
- Andreev V
- Andreev Y
- Andrejkovic JW
- Andrews MB
- Androsov K
- Anguiano J
- Antchev G
- Antequera JB
- Anthony D
- Antunovic Z
- Anuar AAB
- Apollinari G
- Apparu D
- Appelt E
- Apresyan A
- Apyan A
- Araujo M
- Arbol PMRD
- Arcaro D
- Arcidiacono R
- Arenton MW
- Argiro S
- Arneodo M
- Aruta C
- Asavapibhop B
- Asawatangtrakuldee C
- Asenov P
- Asghar MI
- Asilar E
- Askew A
- Asmuss P
- Atakisi IO
- Attikis A
- Auffray E
- Aushev T
- Auzinger G
- Avati V
- Avery P
- Avila C
- Awais A
- Awan MIM
- Ayala E
- Ayala G
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzurri P
- Baarmand MM
- Babaev A
- Bacchetta N
- Bachiller I
- Bachtis M
- Backhaus M
- Baden A
- Baechler J
- Bagliesi G
- Bahinipati S
- Baillon P
- Bainbridge R
- Bakas G
- Bakhshiansohi H
- Bakshi AS
- Ban Y
- Band R
- Bandyopadhyay H
- Banerjee S
- Banerjee S
- Banos LIE
- Bansal S
- Barbagli G
- Barberis E
- Bargassa P
- Baringer P
- Barnes VE
- Barney D
- Baron O
- Barrera CB
- Barrera CO
- Barria P
- Bartek R
- Bartosik N
- BartĂłk M
- Bastos D
- Battilana C
- Baty A
- Bauer G
- Bauerdick LAT
- Baxter S
- Bayatmakou M
- Bayshev I
- Bean A
- Beauceron S
- Beaudette F
- Becerra DAS
- Bechtel J
- Bedoya CF
- Beghin D
- Behera PK
- Behera SC
- Behnke O
- Bein S
- Belforte S
- Bell KW
- Bellan R
- Belloni A
- Bellora A
- Belyaev A
- Belyaev A
- Bemden MV
- Benaglia A
- Benato L
- Bencze G
- Bendavid J
- Benecke A
- Benelli G
- Benitez JF
- Benussi L
- Bergauer T
- Berger P
- Beri SB
- Bernardes CA
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- Berryhill J
- Bertacchi V
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- Bestintzanos I
- Bethani A
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- Bhattacharya R
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- Bhowmik D
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- Bhyun JH
- Bi R
- Bialkowska H
- Bianchini L
- Bianco M
- Bianco S
- Bihan A-CL
- Biino C
- Bilei GM
- Bilin B
- Bindhu VKMN
- Bisello D
- Black K
- Blekman F
- Blinov V
- Bloch D
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- Bloom K
- Bluj M
- Blumenfeld B
- Boccali T
- Bocci A
- Bodek A
- Boimska B
- Boldrini G
- Boletti A
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- Chen HS
- Chen KF
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- Chernyavskaya N
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- Cheung HWK
- Chhibra SS
- Chiarito B
- Chinellato J
- Chistov R
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- Chou JP
- Choudhary BC
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- Christoforou K
- Chudasama R
- Chwalek T
- Ciangottini D
- Cifuentes JAB
- Ciocci MA
- Cipriani M
- Citron M
- Cittolin S
- Ciulli V
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- Clare R
- Clement E
- Clerbaux B
- Cockerill DJA
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- Colaleo A
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- Ălvarez CR
- Ăzçelik Ă
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 19/01/2023
- Field of study
Data availability:
Tabulated results are provided in the HEPData record for this analysis71. Release and preservation of data used by the CMS Collaboration as the basis for publications is guided by the CMS policy as stated in CMS data preservation, re-use and open access policy.Code availability:
The CMS core software is publically available at https://github.com/cms-sw/cmssw.Copyright . Protons consist of three valence quarks, two up-quarks and one down-quark, held together by gluons and a sea of quark-antiquark pairs. Collectively, quarks and gluons are referred to as partons. In a proton-proton collision, typically only one parton of each proton undergoes a hard scattering â referred to as single-parton scattering â leaving the remainder of each proton only slightly disturbed. Here, we report the study of double- and triple-parton scatterings through the simultaneous production of three J/Ï mesons, which consist of a charm quark-antiquark pair, in proton-proton collisions recorded with the CMS experiment at the Large Hadron Collider. We observed this process â reconstructed through the decays of J/Ï mesons into pairs of oppositely charged muons â with a statistical significance above five standard deviations. We measured the inclusive fiducial cross-section to be 272+141â104(stat)±17(syst)fb, and compared it to theoretical expectations for triple-J/Ï meson production in single-, double- and triple-parton scattering scenarios. Assuming factorization of multiple hard-scattering probabilities in terms of single-parton scattering cross-sections, double- and triple-parton scattering are the dominant contributions for the measured process.SCOAP3.Change history:
27 February 2023A Correction to this paper has been published: https://doi.org/10.1038/s41567-023-01992-
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