58 research outputs found

    Wicked Good Sports Medicine Symposium 2012 Program

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    2012 sports medicine symposium at the University of New England in Biddeford, Maine. Presenters and topics included: Daniel E. Lieberman: Why Exercise Really is Medicine (An Evolutionary Explanation); Samuel Headley: Exercise and Chronic Kidney Disease; Stella L. Volpe: Prevention of Weight Gain in a Large Portion Society; J. Timothy Lightfoot: Can You Be Born a Couch Potato? The Genetics that Control Your Physical Activity; Samuel N. Cheuvront: Answers to 10 Common Questions about Hydration; David Epstein: Missing the Phenotypes for the Genotypes.https://dune.une.edu/wgsms/1000/thumbnail.jp

    Should we scale-up? A mixed methods process evaluation of an intervention targeting sedentary office workers using the RE-AIM QuEST framework

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    Background: Interventions targeting a reduction in sedentary behaviour in office workers need to be scaled-up to have impact. In this study, the RE-AIM QuEST framework was used to evaluate the potential for further implementation and scale-up of a consultation based workplace intervention which targeted both the reduction, and breaking up of sitting time.  Methods: To evaluate the Springfield College sedentary behaviour intervention across multiple RE-AIM QuEST indicators; intervention participant, non-participant (employees who did not participate) and key informant (consultation delivery team; members of the research team and stakeholders in workplace health promotion) data were collected using interviews, focus groups and questionnaires. Questionnaires were summarized using descriptive statistics and interviews and focus groups were transcribed verbatim, and thematically analysed.  Results: Barriers to scale-up were: participant burden of activity monitoring; lack of management support; influence of policy; flexibility (scheduling/locations); time and cost. Facilitators to scale up were: visible leadership; social and cultural changes in the workplace; high acceptability; existing health and wellbeing programmes; culture and philosophy of the participating college.  Conclusion: There is potential for scale-up, however adaptations will need to be made to address the barriers to scale-up. Future interventions in office workers should evaluate for scalability during the pilot phases of research

    Supervised Exercise Intervention and Overall Activity in CKD.

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    Introduction: Patients are often instructed to engage in multiple weekly sessions of exercise to increase physical activity. We aimed to determine whether assignment to a supervised exercise regimen increases overall weekly activity in individuals with chronic kidney disease (CKD). Methods: We performed a secondary analysis of a pilot randomized 2 × 2 factorial design trial examining the effects of diet and exercise (10%-15% reduction in caloric intake, 3 supervised exercise sessions/wk, combined diet restriction/exercise, and control). Activity was measured as counts detected by accelerometer. Counts data were collected on all days for which an accelerometer was worn at baseline, month 2, and month 4 follow-up. The primary outcome was a relative change from baseline in log-transformed counts/min. Generalized estimating equations were used to compare the primary outcome in individuals in the exercise group and the nonexercise group. Results: We examined 111 individuals randomized to aerobic exercise or usual activity (n = 48 in the exercise group and n = 44 controls). The mean age was 57 years, 42% were female, and 28% were black. Median overall adherence over all time was 73%. Median (25th, 75th percentile) counts/min over nonsupervised exercise days at months 2 and 4 were 237.5 (6.5, 444.4) for controls and 250.9 (7.7, 529.8) for the exercise group ( Conclusion: Engaging in a supervised exercise program does not increase overall weekly physical activity in individuals with stage 3 to 4 CKD

    Influence of Aerobic Exercise on Appetite-Regulating Hormones, Ghrelin-o-Acyltransferase and Perceived Hunger in Normal Weight and Obese Adults

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    Background: Obesity is a major public health issue in the United States (U.S.), affecting an estimated 78 million US adults. Aerobic exercise (AE) is recommended by the American College of Sports Medicine to prevent and treat obesity, yet the effects of AE on circulating hunger hormones including acylated ghrelin and its biological catalyst, ghrelin o-acyltransferase (GOAT) are less known. Objectives: We investigated the effects of AE on circulating concentrations of appetite regulating hormones and GOAT in a pilot sample of adults classified with normal weight (NW) and obese (OB) body weight status. Methods: Using a quasi-experimental design, nine adults with NW (n=4, body mass index [BMI] = 21.3±1.2 kg/m2 ) and OB (n=5, BMI = 38.9±6.2 kg/m2 ) body weight status completed a preliminary health/fitness assessment. Participants returned to the laboratory on three separate occasions, separated by ≄ 48 hours to perform cycle exercise at 30% and 60% oxygen uptake reserve (VO2 R) or a seated control session with no exercise for 40 min. Fifteen mL of blood was taken pre-and-post exercise and control and were assayed in duplicate. Nonparametric procedures determined whether mean rank differences existed between NW and OB for acylated ghrelin, leptin, insulin, and GOAT in response to exercise and control. Alpha levels were set a priori to p \u3c0.05. Results: Significant mean rank reductions were found in GOAT after compared to before AE and control for NW and OB (p\u3c.05). Significant mean rank differences were found in acylated ghrelin after compared to before performing AE at 60% VO2 R in NW and OB (p\u3c.05); however, differences were not observed between NW and OB (p\u3e.05). Conclusions: Our findings reveal the first available data regarding the effects of AE on GOAT, with NW and OB experiencing equivocal changes pre-to-post AE at 60% VO2 R, and in response to a seated control session

    Effect of treatment of clinical seizures vs electrographic seizures in full-term and near-term neonates : a randomized clinical trial

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    Importance: Seizures in the neonatal period are associated with increased mortality and morbidity. Bedside amplitude-integrated electroencephalography (aEEG) has facilitated the detection of electrographic seizures; however, whether these seizures should be treated remains uncertain. Objective: To determine if the active management of electrographic and clinical seizures in encephalopathic term or near-term neonates improves survival free of severe disability at 2 years of age compared with only treating clinically detected seizures. Design, Setting, and Participants: This randomized clinical trial was conducted in tertiary newborn intensive care units recruited from 2012 to 2016 and followed up until 2 years of age. Participants included neonates with encephalopathy at 35 weeks’ gestation or more and younger than 48 hours old. Data analysis was completed in April 2021. Interventions: Randomization was to an electrographic seizure group (ESG) in which seizures detected on aEEG were treated in addition to clinical seizures or a clinical seizure group (CSG) in which only seizures detected clinically were treated. Main Outcomes and Measures: Primary outcome was death or severe disability at 2 years, defined as scores in any developmental domain more than 2 SD below the Australian mean assessed with Bayley Scales of Neonate and Toddler Development, 3rd ed (BSID-III), or the presence of cerebral palsy, blindness, or deafness. Secondary outcomes included magnetic resonance imaging brain injury score at 5 to 14 days, time to full suck feeds, and individual domain scores on BSID-III at 2 years. Results: Of 212 randomized neonates, the mean (SD) gestational age was 39.2 (1.7) weeks and 122 (58%) were male; 152 (72%) had moderate to severe hypoxic-ischemic encephalopathy (HIE) and 147 (84%) had electrographic seizures. A total of 86 neonates were included in the ESG group and 86 were included in the CSG group. Ten of 86 (9%) neonates in the ESG and 4 of 86 (4%) in the CSG died before the 2-year assessment. The odds of the primary outcome were not significantly different in the ESG group compared with the CSG group (ESG, 38 of 86 [44%] vs CSG, 27 of 86 [31%]; odds ratio [OR], 1.83; 95% CI, 0.96 to 3.49; P = .14). There was also no significant difference in those with HIE (OR, 1.77; 95% CI, 0.84 to 3.73; P = .26). There was evidence that cognitive outcomes were worse in the ESG (mean [SD] scores, ESG: 97.4 [17.7] vs CSG: 103.8 [17.3]; mean difference, −6.5 [95% CI, −1.2 to −11.8]; P = .01). There was little evidence of a difference in secondary outcomes, including time to suck feeds, seizure burden, or brain injury score. Conclusions and Relevance: Treating electrographic and clinical seizures with currently used anticonvulsants did not significantly reduce the rate of death or disability at 2 years in a heterogeneous group of neonates with seizures

    The lure of postwar London:networks of people, print and organisations

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    'Vernacular Voices: Black British Poetry'

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    ABSTRACT Black British poetry is the province of experimenting with voice and recording rhythms beyond the iambic pentameter. Not only in performance poetry and through the spoken word, but also on the page, black British poetry constitutes and preserves a sound archive of distinct linguistic varieties. In Slave Song (1984) and Coolie Odyssey (1988), David Dabydeen employs a form of Guyanese Creole in order to linguistically render and thus commemorate the experience of slaves and indentured labourers, respectively, with the earlier collection providing annotated translations into Standard English. James Berry, Louise Bennett, and Valerie Bloom adapt Jamaican Patois to celebrate Jamaican folk culture and at times to represent and record experiences and linguistic interactions in the postcolonial metropolis. Grace Nichols and John Agard use modified forms of Guyanese Creole, with Nichols frequently constructing gendered voices whilst Agard often celebrates linguistic playfulness. The borders between linguistic varieties are by no means absolute or static, as the emergence and marked growth of ‘London Jamaican’ (Mark Sebba) indicates. Asian British writer Daljit Nagra takes liberties with English for different reasons. Rather than having recourse to established Creole languages, and blending them with Standard English, his heteroglot poems frequently emulate ‘Punglish’, the English of migrants whose first language is Punjabi. Whilst it is the language prestige of London Jamaican that has been significantly enhanced since the 1990s, a fact not only confirmed by linguistic research but also by its transethnic uses both in the streets and on the page, Nagra’s substantial success and the mainstream attention he receives also indicate the clout of vernacular voices in poetry. They have the potential to connect with oral traditions and cultural memories, to record linguistic varieties, and to endow ‘street cred’ to authors and texts. In this chapter, these double-voiced poetic languages are also read as signs of resistance against residual monologic ideologies of Englishness. © Book proposal (02/2016): The Cambridge History of Black and Asian British Writing p. 27 of 4

    Humanics Lecture - "Assessment of Sedentary Behavior at Springfield College - Year-one of a Multi-year Study" - Samuel Headley 2017

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    This is a video of a lecture titled "Assessment of Sedentary Behavior at Springfield College - Year-one of a Multi-year Study" which was presented on April 18, 2017 by the 2016-2017 Distinguished Professor of Humanics, Dr. Samuel Headley. Provost Martha Potvin begins the video with an introduction and recognition of former Distinguished Professors of Humanics that are in attendance. Dr. Headley's presentation focuses on the results of a campuswide study of sedentary behavior. Following Dr. Headley's presentation, Martha Potvin announces the recipients of the Friends of Humanics Scholarships. Springfield College President Mary-Beth Cooper presents scholarship recipients with their certificates. Martha Potvin then introduces the 2017-2018 Distinguished Professor of Humanics, Sue Geyer, who addresses the audience. Further remarks from Martha Potvin conclude the video.Humanics is a word that has a special meaning in the history and philosophy of Springfield College, as well as in the college’s motto of “Spirit, Mind, and Body.” The Oxford English Dictionary defines Humanics as, “the subject or study of human affairs or relations, especially of the human element of a problem or situation as opposed to the mechanical.” In 1962, Dr. Glenn Olds, President of Springfield College at the time, began to wonder why this name was given to the intended philosophy of the college by Dr. Laurence Locke Doggett, Springfield College’s first full-time president. Olds acknowledged that the practices of the faculty were in large part consistent with the Humanics philosophy, but he believed that a more self-conscious application would improve chances of its continuity and survival. To ensure this, a Distinguished Professor of Humanics position was created at the college, first filled by Dr. Seth Arsenian from 1966-1969. The purpose of this position was to catalyze a renewal of consciousness in the philosophy. This was done by annually mandating the Distinguished Professor of Humanics to give a Humanics lecture on the definition of Humanics and what the concept means to them. Arsenian started this tradition in 1967 with his speech titled, “The Meaning of Humanics,” in which he described the concept as a set of ideas, values, and goals that make our college distinct from other colleges and make commitment and unity toward commonly sought goals possible
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