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On velocity and reactive scalar spectra in turbulent premixed flames
AbstractKinetic energy and reactive scalar spectra in turbulent premixed flames are studied from compressible three-dimensional direct numerical simulations (DNS) of a temporally evolving rectangular slot-jet premixed flame, a statistically one-dimensional configuration. The flames correspond to a lean premixed hydrogen–air mixture at an equivalence ratio of 0.7, preheated to 700 K and at 1 atm, and three DNS are considered with a fixed jet Reynolds number of 10 000 and a jet Damköhler number varying between 0.13 and 0.54. For the study of spectra, motivated by the need to account for density change, which can be locally strong in premixed flames, a new density-weighted definition for two-point velocity/scalar correlations is proposed. The density-weighted two-point correlation tensor retains the essential properties of its constant-density (incompressible) counterpart and recovers the density-weighted Reynolds stress tensor in the limit of zero separation. The density weighting also allows the derivation of balance equations for velocity and scalar spectrum functions in the wavenumber space that illuminate physics unique to combusting flows. Pressure–dilatation correlation is a source of kinetic energy at high wavenumbers and, analogously, reaction rate–scalar fluctuation correlation is a high-wavenumber source of scalar energy. These results are verified by the spectra constructed from the DNS data. The kinetic energy spectra show a distinct inertial range with a scaling followed by a ‘diffusive–reactive’ range at higher wavenumbers. The exponential drop-off in this range shows a distinct inflection in the vicinity of the wavenumber corresponding to a laminar flame thickness, , and this is attributed to the contribution from the pressure–dilatation term in the energy balance in wavenumber space. Likewise, a clear spike in spectra of major reactant species (hydrogen) arising from the reaction-rate term is observed at wavenumbers close to . It appears that in the inertial range classical scaling laws for the spectra involving the Kolmogorov scale are applicable, but in the high-wavenumber range where chemical reactions have a strong signature the laminar flame thickness produces a better collapse. It is suggested that a full scaling should perhaps involve the Kolmogorov scale, laminar flame thickness, Damköhler number and Karlovitz number.This is the accepted manuscript. The final version is available from CUP at http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=9317552&fileId=S0022112014003929
Comparison of hydrogen port injection and direct injection (DI) in a single-cylinder dual-fuel diesel engine
Hydrogen direct injection (DI) in a dual-fuel diesel engine is a new technology that can resolve two major issues of its port injection counterpart - knocking and NOx emissions. Compared to widely studied hydrogen port injection in a diesel engine, the hydrogen DI concept executes a near top-dead centre (TDC) injection to cause hydrogen mixing-controlled combustion. The slower burning rate is expected to hinder a rapid pressure rise and subsequent pressure ringing (i.e. knocking) and to reduce NOx emissions, which are problematic in premixed combustion dominant, hydrogen port injection dual-fuel diesel engines. This study directly compares the in-cylinder pressure, efficiency and engine-out emissions of port injected and direct injected hydrogen-diesel dual-fuel combustion in the same engine. The tests were performed in a single-cylinder engine equipped with three injection systems including a hydrogen port injector, a hydrogen direct injector and a common-rail diesel direct injector. The engine was operated at intermediate load using a fixed total energy input of 820 J with hydrogen energy fraction of 50%. The results show that mixing-controlled combustion of the hydrogen in direct injection mode leads to lower in-cylinder pressure and thus lower engine efficiency. However, the severe pressure ringing observed for the hydrogen port injection is avoided and engine-out NOx emission is reduced, indicating the hydrogen DI operation is more stable, its combustion is cleaner and a higher hydrogen utilisation can be achieved
Combustion measurements of waste cooking oil biodiesel
An experimental investigation was performed to assess the combustion characteristics of a waste cooking oil (WCO) biodiesel fuel under simulated compression-ignition engine conditions. A conventional diesel was used as a base fuel for comparison purpose. The fuels were injected into the quiescent steady environment inside a constant-volume combustion chamber (CVCC) of 19.4 kg/m ambient density, 6 MPa ambient pressure, and 1100 K bulk temperature. A range of optical diagnostics were performed, to compare the fuels over ambient O concentrations of 10-21 vol.%, and injection pressures of 70-130 MPa. The results reveal that for the investigated test conditions (i) the lift-off lengths and the first soot distances of the biodiesel are consistently longer than that of diesel; (ii) the peak soot level of the flame increases with the relative distance between the first soot formation and flame liftoff; and (iii) the WCO biodiesel has a lower soot formation propensity than diesel. The fuel liquid lengths were also measured to be shorter than their lift-off distances, indicating no interaction between their spray and combustion processes. 3
Evaluating the landscape of fear between apex predatory sharks and mobile sea turtles across a large dynamic seascape
The ‘‘landscape of fear’’ model has been proposed as a unifying concept in ecology, describing, in part, how animals behave and move about in their environment. The basic model predicts that as an animal’s landscape changes from low to high risk of predation,
prey species will alter their behavior to risk avoidance. However, studies investigating and evaluating the landscape of fear model across large spatial scales (tens to hundreds of thousands of square kilometers) in dynamic, open, aquatic systems involving apex predators and highly mobile prey are lacking. To address this knowledge gap, we investigated predator–prey relationships between tiger sharks (Galeocerdo cuvier) and loggerhead turtles (Caretta caretta) in the North Atlantic Ocean. This included the use of satellite tracking to examine shark and turtle distributions as well as their surfacing behaviors under varying levels of home range overlap. Our findings revealed patterns that deviated from our a priori predictions based on the landscape of fear model. Specifically, turtles did not alter their surfacing behaviors to risk avoidance when overlap in shark–turtle core home range was high. However, in areas of high overlap with turtles, sharks exhibited modified surfacing behaviors that may enhance predation opportunity. We suggest that turtles may be an important factor in determining shark distribution, whereas for turtles, other life history trade-offs may play a larger role in
defining their habitat use. We propose that these findings are a result of both biotic and physically driven factors that independently or synergistically affect predator–prey interactions in this system. These results have implications for evolutionary biology, community ecology, and wildlife conservation. Further, given the difficulty in studying highly migratory marine species, our approach and conclusions may be applied to the study of other predator–prey systems.Bald Head Island ConservancyBritish Chelonia GroupNatural Environmental Research CouncilWAVE Foundation/Newport Aquarium CincinnatiPADI project AWARESEATURTLE.ORGWhitener Foundation (NC); an Endangered Species Act Section 6 Cooperative Agreement with
NOAA Fisheries and the Grays Reef National Marine Sanctuary (South Carolina and Georgia)Batchelor FoundationDinsey Conservation Fun
Water from abandoned mines as a heat source: practical experiences of open- and closed-loop strategies, United Kingdom
Pilot heat pump systems have been installed at two former collieries in Yorkshire/Derbyshire, England, to extract heat from mine water. The installations represent three fundamental configurations of heat exchanger. At Caphouse Colliery, mine water is pumped through a heat exchanger coupled to a heat pump and then discharged to waste (an open-loop heat exchange system). The system performs with high thermal efficiency, but the drawbacks are: (1) it can only be operated when mine water is being actively pumped from the colliery shaft for the purposes of regional water-level management, and (2) the fact that the water is partially oxygenated means that iron oxyhydroxide precipitation occurs, necessitating regular removal of filters for cleaning. At Markham Colliery, near Bolsover, a small amount of mine water is pumped from depth in a flooded shaft, circulated through a heat exchanger coupled to a heat pump and then returned to the same mine shaft at a slightly different depth (a standing column arrangement). This system’s fundamental thermal efficiency is negatively impacted by the electrical power required to run the shaft submersible pump, but clogging issues are not significant. In the third system, at Caphouse, a heat exchanger is submerged in a mine water treatment pond (a closed-loop system). This can be run at any time, irrespective of mine pumping regime, and being a closed-loop system, is not susceptible to clogging issues
Sodium/myo-Inositol Transporters: Substrate Transport Requirements and Regional Brain Expression in the TgCRND8 Mouse Model of Amyloid Pathology
Inositol stereoisomers, myo- and scyllo-inositol, are known to enter the brain and are significantly elevated following oral administration. Elevations in brain inositol levels occur across a concentration gradient as a result of active transport from the periphery. There are two sodium/myo-inositol transporters (SMIT1, SMIT2) that may be responsible for regulating brain inositol levels. The goals of this study were to determine the effects of aging and Alzheimer's disease (AD)-like amyloid pathology on transporter expression, to compare regional expression and to analyze substrate requirements of the inositol transporters. QPCR was used to examine expression of the two transporters in the cortex, hippocampus and cerebellum of TgCRND8 mice, a mouse model of amyloid pathology, in comparison to non-transgenic littermates. In addition, we examined the structural features of inositol required for active transport, utilizing a cell-based competitive uptake assay. Disease pathology did not alter transporter expression in the cortex or hippocampus (p>0.005), with only minimal effects of aging observed in the cerebellum (SMIT1: F2,26 = 12.62; p = 0.0002; SMIT2: F2,26 = 8.71; p = 0.0015). Overall, brain SMIT1 levels were higher than SMIT2, however, regional differences were observed. For SMIT1, at 4 and 6 months cerebellar SMIT1 levels were significantly higher than cortical and hippocampal levels (p<0.05). For SMIT2, at all three ages both cortical and cerebellar SMIT2 levels were significantly higher than hippocampal levels (p<0.05) and at 4 and 6 months of age, cerebellar SMIT2 levels were also significantly higher than cortical levels (p<0.05). Inositol transporter levels are stably expressed as a function of age, and expression is unaltered with disease pathology in the TgCRND8 mouse. Given the fact that scyllo-inositol is currently in clinical trials for the treatment of AD, the stable expression of inositol transporters regardless of disease pathology is an important finding
Characterizing the gamma-ray long-term variability of PKS 2155-304 with H.E.S.S. and Fermi-LAT
Studying the temporal variability of BL Lac objects at the highest energies
provides unique insights into the extreme physical processes occurring in
relativistic jets and in the vicinity of super-massive black holes. To this
end, the long-term variability of the BL Lac object PKS 2155-304 is analyzed in
the high (HE, 100 MeV 200 GeV)
gamma-ray domain. Over the course of ~9 yr of H.E.S.S observations the VHE
light curve in the quiescent state is consistent with a log-normal behavior.
The VHE variability in this state is well described by flicker noise
(power-spectral-density index {\ss}_VHE = 1.10 +0.10 -0.13) on time scales
larger than one day. An analysis of 5.5 yr of HE Fermi LAT data gives
consistent results ({\ss}_HE = 1.20 +0.21 -0.23, on time scales larger than 10
days) compatible with the VHE findings. The HE and VHE power spectral densities
show a scale invariance across the probed time ranges. A direct linear
correlation between the VHE and HE fluxes could neither be excluded nor firmly
established. These long-term-variability properties are discussed and compared
to the red noise behavior ({\ss} ~ 2) seen on shorter time scales during
VHE-flaring states. The difference in power spectral noise behavior at VHE
energies during quiescent and flaring states provides evidence that these
states are influenced by different physical processes, while the compatibility
of the HE and VHE long-term results is suggestive of a common physical link as
it might be introduced by an underlying jet-disk connection.Comment: 11 pages, 16 figure
Penetrance of pathogenic genetic variants associated with premature ovarian insufficiency
This is the author accepted manuscript. The final version is available from Nature Research via the DOI in this recordData availability:
We used publicly available individual-level genotype and phenotype data from the UK Biobank (https://biobank.ndph.ox.ac.uk/showcase/). Access to these data needs to be requested from the UK Biobank (https://www.ukbiobank.ac.uk/enable-your-research/apply-for-access). This research was conducted using the UK Biobank Resource under application 9905 (University of Cambridge) and 9072 and 871 (University of Exeter). POI genes were identified from the GEL Panel App (https://panelapp.genomicsengland.co.uk/panels/155/). Genes were annotated with pathogenicity constraint metrics from gnomAD v.2.1.1.Premature ovarian insufficiency (POI) affects 1% of women and is a leading cause of infertility. It is often considered to be a monogenic disorder, with pathogenic variants in ~100 genes described in the literature. We sought to systematically evaluate the penetrance of variants in these genes using exome sequence data in 104,733 women from the UK Biobank, 2,231 (1.14%) of whom reported at natural menopause under the age of 40 years. We found limited evidence to support any previously reported autosomal dominant effect. For nearly all heterozygous effects on previously reported POI genes, we ruled out even modest penetrance, with 99.9% (13,699 out of 13,708) of all protein-truncating variants found in reproductively healthy women. We found evidence of haploinsufficiency effects in several genes, including TWNK (1.54 years earlier menopause, P = 1.59 × 10-6) and SOHLH2 (3.48 years earlier menopause, P = 1.03 × 10-4). Collectively, our results suggest that, for the vast majority of women, POI is not caused by autosomal dominant variants either in genes previously reported or currently evaluated in clinical diagnostic panels. Our findings, plus previous studies, suggest that most POI cases are likely oligogenic or polygenic in nature, which has important implications for future clinical genetic studies, and genetic counseling for families affected by POI.Medical Research Council (MRC)National Institute for Health and Care Research (NIHR)QUEX InstituteUniversity of CambridgeCancer Research UKInnovative Medicines Initiative 2 Joint UndertakingNational Health and Medical Research CouncilEuropean Research Council (ERC)Novo Nordisk FoundationIndependent Research Foundation DenmarkDanish National Research Foundation Centr
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
Search for the neutral Higgs bosons of the minimal supersymmetric standard model in pp collisions at root s=7 TeV with the ATLAS detector
A search for neutral Higgs bosons of the Minimal Supersymmetric Standard Model (MSSM) is reported. The analysis is based on a sample of proton-proton collisions at a centre-of-mass energy of 7TeV recorded with the ATLAS detector at the Large Hadron Collider. The data were recorded in 2011 and correspond to an integrated luminosity of 4.7 fb-1 to 4.8 fb-1. Higgs boson decays into oppositely-charged muon or τ lepton pairs are considered for final states requiring either the presence or absence of b-jets. No statistically significant excess over the expected background is observed and exclusion limits at the 95% confidence level are derived. The exclusion limits are for the production cross-section of a generic neutral Higgs boson, φ, as a function of the Higgs boson mass and for h/A/H production in the MSSM as a function of the parameters mA and tan β in the mhmax scenario for mA in the range of 90GeV to 500 GeV. Copyright CERN
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