26 research outputs found

    Prevalence of Low Birth Weight and Associated Factors Among Women Delivered in Debre Markos Referral Hospital, East Gojam, Ethiopia, 2017

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    Introduction:  low birth weight is defined as birth weight less than 2,500gram irrespective of gestational age. More than 20 million infant are born each year weighing less than 2,500gram, accounting 17% of all birth in developing world. Similarly, according to Ethiopia demographic and health survey (EDHS, 2011), 11% weighed less than 2,500gm. Birth weight is an important role in infant mortality and morbidity, development and future health of the child. Objective: The main objective of the study was to assess the prevalence of low birth weight and factor among women delivered in Debre Markos Referral Hospital, East Gojam, Ethiopia, 2017. Methodology: The study was institutional based cross sectional study design conducting by reviewing cards of mother who delivered in Debre Markos Referral Hospital from June 1, 2017 to August 5, 2017. Simple random sampling technique was used. Our sample size was 243 and the data were collected by using structured questioner.   The data was entered by SPSS software version 20.0. Result and discussion: In this study 243 mother cards were included yielding 100% response rate. Out of 243 mothers, 36.3% participant was between age group 25-29 years. The prevalence of low birth weight in this study was 26.3%.ANC visit were significant associated with low birth weight (AOR, 0.285, 95% CI=0.111, 0.728, P-value=0.009). The sex of neonate was significantly associated with LBW (AOR=0.548, 95% CI= 0.303, 0.994, p-value =0.048. Additionally, and anemia [hemoglobin level] was significant associated with neonatal birth weight (AOR=0.129[87.1%], 95% CI=0.016, 1.011, p-value =0.054. Conclusion and Recommendation: The finding of this study concludes that the prevalence of low birth weight was 26.3%. The determinant factor for LBW were ANC visit, sex of neonate and anemia during pregnancy. Keywords: low birth weight, magnitude, associated factor

    Utilization of Long Acting and Permanent Contraceptive Methods and Associated Factors among Women of Modern Contraceptive Users in Debre Markos town, North West Ethiopia, 2016

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    Introduction: Globally utilization of long acting and permanent contraceptive methods is high in which more than fifty percent of contraceptive users were practicing female sterilization and intrauterine contraceptive device, but in sub-Saharan countries the proportion of women using long acting and permanent contraceptive methods is significantly lower than the proportion using short-acting methods. Particularly in Ethiopia, despite the fact that utilization of long acting and permanent methods are believed to be low, there are limited evidences on the real magnitude of utilization of the methods and associated factors.Objective: This study was aimed to assess utilization of long acting and permanent contraceptive methods and associated factors among women of modern contraceptive users in Debre Markos town, North West Ethiopia, 2016 Methods: Community based cross sectional study was conducted from January 13-29, 2016. Systematic random sampling technique was used to select 455 study participants. Pre tested structured Amharic version questionnaire was used to collect the data through interview. Both bivariate and multiple logistic regressions were used to identify associated factors. Results: Out of the total modern contraceptive users 213(46.8%) were using long acting and permanent contraceptive methods and from them 165(77.5%) were using implants.  modern contraceptive user mothers who had information about other contraceptive methods that could be used from FP service providers  were 14 times more likely to utilize long acting and permanent contraceptive methods as compared to participants who hadn’t information about other contraceptive methods from family planning service providers(AOR=13.77; 95% CI: 6.30, 30.10). Desired number of children, future reproductive plan, and having common choice of contraceptive method by discussion were also significantly associated with utilization of long acting and permanent contraceptive methods.Conclusion and Recommendations: Long-acting and permanent contraceptive methods utilization in this study was relatively high. To further increase and meet the national plan involving husbands during counseling service, ensuring sustainable availability and accessibility of long acting and permanent contraceptive methods is needed. Keywords: contraceptive users, Long acting and permanent contraceptive methods, Modern contraceptive methods,  Utilizatio

    Knowledge and Health Care Seeking Behaviour About Neonatal Danger Signs Among Mothers Visiting Immunization Unit in Public Health Facilities of Debre Markos Town Northwest Ethiopia, June 2016

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    Background: Worldwide the average neonatal mortality was estimated to be 33 per 1000 live births. It is estimated that each year four million neonatal deaths occur, and almost exclusively in low income countries. Danger signs in the neonatal period are nonspecific and can be a manifestation of almost any newborn disease. One of the component in reducing the newborn morbidity and mortality is early recognition of sick newborn and the danger signs of illness and initiation of prompt treatment. Objective: To assess knowledge and health care seeking behaviour about neonatal danger signs among mothers visiting immunization unit in Public Health Facilities of Debre Markos Town 2016. Method: A facility based cross sectional study will be employed to assess knowledge and health care seeking behaviour of mothers about neonatal danger signs among mothers visiting immunization unit in public health facilities of Debre Markos, North Waste Ethiopia. Quantitative method of data collection will be deployed by using pre-tested structured interviewer administered questionnaire from a sample of 285 respondents. Systematic random sampling techniques were employed to select mothers with less than 1 year old infant. Result: From the total respondents, about 197(69.1 %) mothers knew at least one neonatal danger signs. The most common mentioned neonatal danger signs were persistent vomiting, 133(70.7%), difficulty of breathing 132(69.8%), diarrhea 127(67.6%), and fever 124(66.0%).Only 35(18.6%), 26(9.7%), 8(2.9%) and 7(2.60%) identified pus discharge from umbilicus, hypothermia (decrease temperature), lethargy/unconsciousness and convulsions as neonatal danger signs respectively. Conclusion and Recommendation: Most of the mothers were knowledgeable about neonatal danger signs. but, the rest who had no awareness and health care seeking practice should be addressed through maternal and child health services by designing an appropriate strategies including provision of targeted information, education and communication. Keywords: Knowledge, Health care seeking behavior, Neonatal danger signs DOI: 10.7176/JMPB/52-0

    Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019

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    Background: Updated data on chronic respiratory diseases (CRDs) are vital in their prevention, control, and treatment in the path to achieving the third UN Sustainable Development Goals (SDGs), a one-third reduction in premature mortality from non-communicable diseases by 2030. We provided global, regional, and national estimates of the burden of CRDs and their attributable risks from 1990 to 2019. Methods: Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we estimated mortality, years lived with disability, years of life lost, disability-adjusted life years (DALYs), prevalence, and incidence of CRDs, i.e. chronic obstructive pulmonary disease (COPD), asthma, pneumoconiosis, interstitial lung disease and pulmonary sarcoidosis, and other CRDs, from 1990 to 2019 by sex, age, region, and Socio-demographic Index (SDI) in 204 countries and territories. Deaths and DALYs from CRDs attributable to each risk factor were estimated according to relative risks, risk exposure, and the theoretical minimum risk exposure level input. Findings: In 2019, CRDs were the third leading cause of death responsible for 4.0 million deaths (95% uncertainty interval 3.6–4.3) with a prevalence of 454.6 million cases (417.4–499.1) globally. While the total deaths and prevalence of CRDs have increased by 28.5% and 39.8%, the age-standardised rates have dropped by 41.7% and 16.9% from 1990 to 2019, respectively. COPD, with 212.3 million (200.4–225.1) prevalent cases, was the primary cause of deaths from CRDs, accounting for 3.3 million (2.9–3.6) deaths. With 262.4 million (224.1–309.5) prevalent cases, asthma had the highest prevalence among CRDs. The age-standardised rates of all burden measures of COPD, asthma, and pneumoconiosis have reduced globally from 1990 to 2019. Nevertheless, the age-standardised rates of incidence and prevalence of interstitial lung disease and pulmonary sarcoidosis have increased throughout this period. Low- and low-middle SDI countries had the highest age-standardised death and DALYs rates while the high SDI quintile had the highest prevalence rate of CRDs. The highest deaths and DALYs from CRDs were attributed to smoking globally, followed by air pollution and occupational risks. Non-optimal temperature and high body-mass index were additional risk factors for COPD and asthma, respectively. Interpretation: Albeit the age-standardised prevalence, death, and DALYs rates of CRDs have decreased, they still cause a substantial burden and deaths worldwide. The high death and DALYs rates in low and low-middle SDI countries highlights the urgent need for improved preventive, diagnostic, and therapeutic measures. Global strategies for tobacco control, enhancing air quality, reducing occupational hazards, and fostering clean cooking fuels are crucial steps in reducing the burden of CRDs, especially in low- and lower-middle income countries

    Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-Adjusted life-years for 29 cancer groups, 1990 to 2017 : A systematic analysis for the global burden of disease study

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    Importance: Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the 2011 Political Declaration on the Prevention and Control of Noncommunicable Diseases and the third Sustainable Development Goal. Lack of situational analyses, priority setting, and budgeting have been identified as major obstacles in achieving these goals. All of these have in common that they require information on the local cancer epidemiology. The Global Burden of Disease (GBD) study is uniquely poised to provide these crucial data. Objective: To describe cancer burden for 29 cancer groups in 195 countries from 1990 through 2017 to provide data needed for cancer control planning. Evidence Review: We used the GBD study estimation methods to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-Adjusted life-years (DALYs). Results are presented at the national level as well as by Socio-demographic Index (SDI), a composite indicator of income, educational attainment, and total fertility rate. We also analyzed the influence of the epidemiological vs the demographic transition on cancer incidence. Findings: In 2017, there were 24.5 million incident cancer cases worldwide (16.8 million without nonmelanoma skin cancer [NMSC]) and 9.6 million cancer deaths. The majority of cancer DALYs came from years of life lost (97%), and only 3% came from years lived with disability. The odds of developing cancer were the lowest in the low SDI quintile (1 in 7) and the highest in the high SDI quintile (1 in 2) for both sexes. In 2017, the most common incident cancers in men were NMSC (4.3 million incident cases); tracheal, bronchus, and lung (TBL) cancer (1.5 million incident cases); and prostate cancer (1.3 million incident cases). The most common causes of cancer deaths and DALYs for men were TBL cancer (1.3 million deaths and 28.4 million DALYs), liver cancer (572000 deaths and 15.2 million DALYs), and stomach cancer (542000 deaths and 12.2 million DALYs). For women in 2017, the most common incident cancers were NMSC (3.3 million incident cases), breast cancer (1.9 million incident cases), and colorectal cancer (819000 incident cases). The leading causes of cancer deaths and DALYs for women were breast cancer (601000 deaths and 17.4 million DALYs), TBL cancer (596000 deaths and 12.6 million DALYs), and colorectal cancer (414000 deaths and 8.3 million DALYs). Conclusions and Relevance: The national epidemiological profiles of cancer burden in the GBD study show large heterogeneities, which are a reflection of different exposures to risk factors, economic settings, lifestyles, and access to care and screening. The GBD study can be used by policy makers and other stakeholders to develop and improve national and local cancer control in order to achieve the global targets and improve equity in cancer care. © 2019 American Medical Association. All rights reserved.Peer reviewe

    Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021

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    This online publication has been corrected. The corrected version first appeared at thelancet.com on September 28, 2023BACKGROUND : Diabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), we produced location-specific, age-specific, and sex-specific estimates of diabetes prevalence and burden from 1990 to 2021, the proportion of type 1 and type 2 diabetes in 2021, the proportion of the type 2 diabetes burden attributable to selected risk factors, and projections of diabetes prevalence through 2050. METHODS : Estimates of diabetes prevalence and burden were computed in 204 countries and territories, across 25 age groups, for males and females separately and combined; these estimates comprised lost years of healthy life, measured in disability-adjusted life-years (DALYs; defined as the sum of years of life lost [YLLs] and years lived with disability [YLDs]). We used the Cause of Death Ensemble model (CODEm) approach to estimate deaths due to diabetes, incorporating 25 666 location-years of data from vital registration and verbal autopsy reports in separate total (including both type 1 and type 2 diabetes) and type-specific models. Other forms of diabetes, including gestational and monogenic diabetes, were not explicitly modelled. Total and type 1 diabetes prevalence was estimated by use of a Bayesian meta-regression modelling tool, DisMod-MR 2.1, to analyse 1527 location-years of data from the scientific literature, survey microdata, and insurance claims; type 2 diabetes estimates were computed by subtracting type 1 diabetes from total estimates. Mortality and prevalence estimates, along with standard life expectancy and disability weights, were used to calculate YLLs, YLDs, and DALYs. When appropriate, we extrapolated estimates to a hypothetical population with a standardised age structure to allow comparison in populations with different age structures. We used the comparative risk assessment framework to estimate the risk-attributable type 2 diabetes burden for 16 risk factors falling under risk categories including environmental and occupational factors, tobacco use, high alcohol use, high body-mass index (BMI), dietary factors, and low physical activity. Using a regression framework, we forecast type 1 and type 2 diabetes prevalence through 2050 with Socio-demographic Index (SDI) and high BMI as predictors, respectively. FINDINGS : In 2021, there were 529 million (95% uncertainty interval [UI] 500–564) people living with diabetes worldwide, and the global age-standardised total diabetes prevalence was 6·1% (5·8–6·5). At the super-region level, the highest age-standardised rates were observed in north Africa and the Middle East (9·3% [8·7–9·9]) and, at the regional level, in Oceania (12·3% [11·5–13·0]). Nationally, Qatar had the world’s highest age-specific prevalence of diabetes, at 76·1% (73·1–79·5) in individuals aged 75–79 years. Total diabetes prevalence—especially among older adults—primarily reflects type 2 diabetes, which in 2021 accounted for 96·0% (95·1–96·8) of diabetes cases and 95·4% (94·9–95·9) of diabetes DALYs worldwide. In 2021, 52·2% (25·5–71·8) of global type 2 diabetes DALYs were attributable to high BMI. The contribution of high BMI to type 2 diabetes DALYs rose by 24·3% (18·5–30·4) worldwide between 1990 and 2021. By 2050, more than 1·31 billion (1·22–1·39) people are projected to have diabetes, with expected age-standardised total diabetes prevalence rates greater than 10% in two super-regions: 16·8% (16·1–17·6) in north Africa and the Middle East and 11·3% (10·8–11·9) in Latin America and Caribbean. By 2050, 89 (43·6%) of 204 countries and territories will have an age-standardised rate greater than 10%. INTERPRETATION : Diabetes remains a substantial public health issue. Type 2 diabetes, which makes up the bulk of diabetes cases, is largely preventable and, in some cases, potentially reversible if identified and managed early in the disease course. However, all evidence indicates that diabetes prevalence is increasing worldwide, primarily due to a rise in obesity caused by multiple factors. Preventing and controlling type 2 diabetes remains an ongoing challenge. It is essential to better understand disparities in risk factor profiles and diabetes burden across populations, to inform strategies to successfully control diabetes risk factors within the context of multiple and complex drivers.Bill & Melinda Gates Foundation.http://www.thelancet.comam2024School of Health Systems and Public Health (SHSPH)SDG-03:Good heatlh and well-bein

    Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

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    BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021.MethodsWe estimated mortality, prevalence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs), with corresponding 95% uncertainty intervals (UIs), by age and sex in 204 countries and territories, from 1990 to 2021. We included morbidity and deaths due to neurological conditions, for which health loss is directly due to damage to the CNS or peripheral nervous system. We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, preterm birth, and sepsis), infectious diseases (ie, COVID-19, cystic echinococcosis, malaria, syphilis, and Zika virus disease), and diabetic neuropathy. By conducting a sequela-level analysis of the health outcomes for these conditions, only cases where nervous system damage occurred were included, and YLDs were recalculated to isolate the non-fatal burden directly attributable to nervous system health loss. A comorbidity correction was used to calculate total prevalence of all conditions that affect the nervous system combined.FindingsGlobally, the 37 conditions affecting the nervous system were collectively ranked as the leading group cause of DALYs in 2021 (443 million, 95% UI 378–521), affecting 3·40 billion (3·20–3·62) individuals (43·1%, 40·5–45·9 of the global population); global DALY counts attributed to these conditions increased by 18·2% (8·7–26·7) between 1990 and 2021. Age-standardised rates of deaths per 100 000 people attributed to these conditions decreased from 1990 to 2021 by 33·6% (27·6–38·8), and age-standardised rates of DALYs attributed to these conditions decreased by 27·0% (21·5–32·4). Age-standardised prevalence was almost stable, with a change of 1·5% (0·7–2·4). The ten conditions with the highest age-standardised DALYs in 2021 were stroke, neonatal encephalopathy, migraine, Alzheimer's disease and other dementias, diabetic neuropathy, meningitis, epilepsy, neurological complications due to preterm birth, autism spectrum disorder, and nervous system cancer.InterpretationAs the leading cause of overall disease burden in the world, with increasing global DALY counts, effective prevention, treatment, and rehabilitation strategies for disorders affecting the nervous system are needed

    Agro ecological base differences of village based local chicken performance and household product consumption in Amhara Region, Ethiopia

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    AbstractThe study was conducted to describe village-based local chicken performance, major husbandry practices, and product consumption habits of households in an agro ecological base. Multi-stage sampling techniques were applied for this study. Semi-structured questionnaire, field observation, and key informant interview methods of data collection were used. The majority of households (71.00%) were providing supplementary feed for their chickens. Feed supplementation practices in the lowland areas were significantly lower (p < 0.05) and accounted for 46.24% of respondents. In the study area, 57.33% of respondents were faced disease problems which were significantly higher (p < 0.05) in lowland areas. Most of respondents (81.67%) used ethno veterinary to treat their ill chickens. Annual egg production/hen, number of eggs/hen/clutch, number of clutches/hen/year, age of cockerels at first mating, pullets at first egg laying, number of egg set/brooding were 61.91 ± 5.70, 14.34 ± 1.69, 3.44 ± 0.44, 5.76 ± 0.68 months, 6.26 ± 0.26 months, and 11.95 ± 1.55, respectively. The survey also indicated that survived chick to market age (66.45 ± 6.83%), male age at slaughter (9.16 ± 1.02 months), number of eggs hatched per incubation (9.60 ± 1.36), and hatchability percentage were 79.90 ± 4.48%. The number of eggs consumed/per capita/year, and average numbers of slaughtered chickens/year for home consumption were 46.54 ± 29.44, and 1.46 ± 1.50, respectively, which were significantly lower (P < 0.05) in lowland areas. Generally, most of the performances of local chickens and chicken product consumption habits were poor in the areas. Therefore, agro ecological base improvement intervention about breed, feeds and feeding strategies, health care management, and awareness of households on product utilization are vital in the study area

    Performance evaluation and sustainability challenges of tropically adopted exotic chicken breeds in Northwest Ethiopia

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    AbstractThe study aimed to describe performance and challenges of village-based exotic chicken production in Northwest Ethiopia. Three zones, 13 districts, and 300 households were selected. The data were collected via semi-structured questionnaires, field observations, and key informant interviews. In the study area, the average exotic chicken holding per household was 4.27 ± 0.13 birds. The most dominant flocks were hens followed by pullets with high significant difference (P < 0.01) in the midland agro ecology. The annual number of egg production of Sasso, Bovans brown, and Koekoek was 110.99 ± 1.45, 123.29 ± 1.16, and 102.92 ± 1.22, respectively. The average age of pullets at first egg laying was 5.25 ± 0.03 (Sasso), 5.53 ± 0.02 (Bovans brown), and 5.71 ± 0.03 (Koekoek) months. The age of cockerels (mean ± SE) at first mating was 4.18 ± 0.06 (Sasso), 4.89 ± 0.06 (Bovans brown), and 5.15 ± 0.06 (Koekoek) months. Male age (mean ± SE) at slaughter of Sasso, Bovans brown, and Koekoek were 4.24 ± 0.06, 6.28 ± 0.05, and 5.68 ± 0.06 months, respectively. The lack of improved breed supply was the first production challenge followed by feed shortages and disease outbreaks. Therefore, designing exotic chicken market supply, practicing ration formulation with locally available feed resources, controlling disease, and predator with biosecurity measures and other proper management strategies in respective of agro ecologies could be mandatory
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