A Listing of Current Books

With the rapid increase in the research of promising technologies such as vehicle platooning, which are trying to find more fuel-efficient ways of operating our transportation systems, complex questions requiring creative solutions arise. Regarded as an up-and-coming technology that is expected to be highly relevant and widely applied in the near future, vehicle platooning allows the smart manipulation of the traffic by grouping two or more vehicles into a single convoy and coordinating its behavior, all the while guaranteeing a safe and fuel-efficient freight operation. This thesis tackles the specific problem in which two platoons of heavyduty vehicles (HDVs), coming from different highways, would like to be merged into a single one and remain driving as a larger platoon using the least amount of fuel possible. This can be beneficial if the HDVs need to travel a long distance after the merging point and fuel savings of up to 8% can be achieved by platooning along this trajectory. The focus lies on the calculation of the optimal input policies that minimize the fuel consumption of both platoons while completing the merging maneuver. Some theoretical background on optimal control and the minimum principle is introduced and it is consequently applied on a nonlinear model of the HDVs dynamics. The culmination of this approach is the solution of the inputconstrained, free end-time optimization problem. Due to the non-linearity of the model and the conditions set by the minimum principle numerical integration techniques, such as the shooting method, are also presented. In a final stage, this optimization tool is used together with shrinking horizon model predictive control to create a controller that is capable of accounting for disturbances, speed constraints and model uncertainties. The final result of this thesis is a control algorithm that can merge two platoons of any length, even in the presence of undesirable disturbances by correcting the optimal policies accordingly, in the most fuel-efficient manner

Large scale geometry and evolution of a universe with radiation pressure and cosmological constant

In view of new experimental results that strongly suggest a non-zero cosmological constant, it becomes interesting to revisit the Friedman-Lemaitre model of evolution of a universe with cosmological constant and radiation pressure. In this paper, we discuss the explicit solutions for that model and perform numerical explorations for reasonable values of cosmological parameters. We also analyse the behaviour of redshifts in such models and the description of ``very large scale geometrical features'' when analysed by distant observers.Comment: 31 pages, Latex, 9 eps figures. Revised version: Introduction was extended and we have added an application to cosmology of the duplication formula for the elliptic Weierstrass P functio

Wavelets on Discrete Fields

International audienceAn arithmetic version of continuous wavelet analysis is described. Starting from a square-integrable representation of the affine group of Z Z p (or Z Z) it is shown how wavelet decom-positions of ℓ 2 (Z Z p) can be obtained. Moreover, a redefinition of the dilation operator on ℓ 2 (Z Z p) directly yields an algorithmic structure similar to that appearing with multiresolution analyses

Decoding the nucleoid organisation of Bacillus subtilis and Escherichia coli through gene expression data

BACKGROUND: Although the organisation of the bacterial chromosome is an area of active research, little is known yet on that subject. The difficulty lies in the fact that the system is dynamic and difficult to observe directly. The advent of massive hybridisation techniques opens the way to further studies of the chromosomal structure because the genes that are co-expressed, as identified by microarray experiments, probably share some spatial relationship. The use of several independent sets of gene expression data should make it possible to obtain an exhaustive view of the genes co-expression and thus a more accurate image of the structure of the chromosome. RESULTS: For both Bacillus subtilis and Escherichia coli the co-expression of genes varies as a function of the distance between the genes along the chromosome. The long-range correlations are surprising: the changes in the level of expression of any gene are correlated (positively or negatively) to the changes in the expression level of other genes located at well-defined long-range distances. This property is true for all the genes, regardless of their localisation on the chromosome. We also found short-range correlations, which suggest that the location of these co-expressed genes corresponds to DNA turns on the nucleoid surface (14–16 genes). CONCLUSION: The long-range correlations do not correspond to the domains so far identified in the nucleoid. We explain our results by a model of the nucleoid solenoid structure based on two types of spirals (short and long). The long spirals are uncoiled expressed DNA while the short ones correspond to coiled unexpressed DNA

Nextet

Program listing performers and works performed

Medulloblastoma Exome Sequencing Uncovers Subtype-Specific Somatic Mutations

Medulloblastomas are the most common malignant brain tumors in children1. Identifying and understanding the genetic events that drive these tumors is critical for the development of more effective diagnostic, prognostic and therapeutic strategies. Recently, our group and others described distinct molecular subtypes of medulloblastoma based on transcriptional and copy number profiles2–5. Here, we utilized whole exome hybrid capture and deep sequencing to identify somatic mutations across the coding regions of 92 primary medulloblastoma/normal pairs. Overall, medulloblastomas exhibit low mutation rates consistent with other pediatric tumors, with a median of 0.35 non-silent mutations per megabase. We identified twelve genes mutated at statistically significant frequencies, including previously known mutated genes in medulloblastoma such as CTNNB1, PTCH1, MLL2, SMARCA4 and TP53. Recurrent somatic mutations were identified in an RNA helicase gene, DDX3X, often concurrent with CTNNB1 mutations, and in the nuclear co-repressor (N-CoR) complex genes GPS2, BCOR, and LDB1, novel findings in medulloblastoma. We show that mutant DDX3X potentiates transactivation of a TCF promoter and enhances cell viability in combination with mutant but not wild type beta-catenin. Together, our study reveals the alteration of Wnt, Hedgehog, histone methyltransferase and now N-CoR pathways across medulloblastomas and within specific subtypes of this disease, and nominates the RNA helicase DDX3X as a component of pathogenic beta-catenin signaling in medulloblastoma

Pseudorapidity and transverse momentum dependence of flow harmonics in pPb and PbPb collisions

info:eu-repo/semantics/publishe

Search for supersymmetry in proton-proton collisions at 13 TeV using identified top quarks

A search for supersymmetry is presented based on proton-proton collision events containing identified hadronically decaying top quarks, no leptons, and an imbalance p(T)(miss) in transverse momentum. The data were collected with the CMS detector at the CERN LHC at a center-of-mass energy of 13 TeV, and correspond to an integrated luminosity of 35.9 fb(-1). Search regions are defined in terms of the multiplicity of bottom quark jet and top quark candidates, the p(T)(miss) , the scalar sum of jet transverse momenta, and themT2 mass variable. No statistically significant excess of events is observed relative to the expectation from the standard model. Lower limits on the masses of supersymmetric particles are determined at 95% confidence level in the context of simplified models with top quark production. For a model with direct top squark pair production followed by the decay of each top squark to a top quark and a neutralino, top squark masses up to 1020 GeVand neutralino masses up to 430 GeVare excluded. For amodel with pair production of gluinos followed by the decay of each gluino to a top quark-antiquark pair and a neutralino, gluino masses up to 2040 GeVand neutralino masses up to 1150 GeVare excluded. These limits extend previous results.Peer reviewe

Search for Evidence of the Type-III Seesaw Mechanism in Multilepton Final States in Proton-Proton Collisions at root s=13 TeV

Peer reviewe

Search for Higgsino pair production in pp collisions at root s=13 TeV in final states with large missing transverse momentum and two Higgs bosons decaying via H -> b(b)over bar

Results are reported from a search for new physics in 13 TeV proton-proton collisions in the final state with large missing transverse momentum and two Higgs bosons decaying via H -> b(b)over bar. The search uses a data sample accumulated by the CMS experiment at the LHC in 2016, corresponding to an integrated luminosity of 35.9 fb(-1). The search is motivated by models based on gauge-mediated supersymmetry breaking, which predict the electroweak production of a pair of Higgsinos, each of which can decay via a cascade process to a Higgs boson and an undetected lightest supersymmetric particle. The observed event yields in the signal regions are consistent with the standard model background expectation obtained from control regions in data. Higgsinos in the mass range 230-770 GeV are excluded at 95% confidence level in the context of a simplified model for the production and decay of approximately degenerate Higgsinos.Peer reviewe