On the Apparent Orbital Inclination Change of the Extrasolar Transiting Planet TrES-2b

On June 15, 2009 UT the transit of TrES-2b was detected using the University of Arizona's 1.55 meter Kuiper Telescope with 2.0-2.5 millimag RMS accuracy in the I-band. We find a central transit time of $T_c = 2454997.76286 \pm0.00035$ HJD, an orbital period of $P = 2.4706127 \pm 0.0000009$ days, and an inclination angle of $i = 83^{\circ}.92 \pm 0.05$, which is consistent with our re-fit of the original I-band light curve of O'Donovan et al. (2006) where we find $i = 83^{\circ}.84 \pm0.05$. We calculate an insignificant inclination change of $\Delta i = -0^{\circ}.08 \pm 0.07$ over the last 3 years, and as such, our observations rule out, at the $\sim 11 \sigma$ level, the apparent change of orbital inclination to $i_{predicted} = 83^{\circ}.35 \pm0.1$ as predicted by Mislis and Schmitt (2009) and Mislis et al. (2010) for our epoch. Moreover, our analysis of a recently published Kepler Space Telescope light curve (Gilliland et al. 2010) for TrES-2b finds an inclination of $i = 83^{\circ}.91 \pm0.03$ for a similar epoch. These Kepler results definitively rule out change in $i$ as a function of time. Indeed, we detect no significant changes in any of the orbital parameters of TrES-2b.Comment: 19 pages, 1 table, 7 figures. Re-submitted to ApJ, January 14, 201

Understanding the association between negative symptoms and performance on effort-based decision-making tasks: The importance of defeatist performance beliefs

Effort-based decision-making paradigms are increasingly utilized to gain insight into the nature of motivation deficits. Research has shown associations between effort-based decision making and experiential negative symptoms; however, the associations are not consistent. The current study had two primary goals. First, we aimed to replicate previous findings of a deficit in effort-based decision making among individuals with schizophrenia on a test of cognitive effort. Second, in a large sample combined from the current and a previous study, we sought to examine the association between negative symptoms and effort by including the related construct of defeatist beliefs. The results replicated previous findings of impaired cognitive effort-based decision making in schizophrenia. Defeatist beliefs significantly moderated the association between negative symptoms and effort-based decision making such that there was a strong association between high negative symptoms and deficits in effort-based decision making, but only among participants with high levels of defeatist beliefs. Thus, our findings suggest the relationship between negative symptoms and effort performance may be understood by taking into account the role of defeatist beliefs, and finding that might explain discrepancies in previous studies

Follow-up Observations of the Neptune Mass Transiting Extrasolar Planet HAT-P-11b

We have confirmed the existence of the transiting super Neptune extrasolar planet HAT-P-11b. On May 1, 2009 UT the transit of HAT-P-11b was detected at the University of Arizona's 1.55m Kuiper Telescope with 1.7 millimag rms accuracy. We find a central transit time of T_c = 2454952.92534+/-0.00060 BJD; this transit occurred 80+/-73 seconds sooner than previous measurements (71 orbits in the past) would have predicted. Hence, our transit timing rules out the presence of any large (>200 s) deviations from the ephemeris of Bakos et al. (2009). We obtain a slightly more accurate period of P=4.8878045+/-0.0000043 days. We measure a slightly larger planetary radius of R_p=0.452+/-0.020 R_J (5.07+/-0.22 R_earth) compared to Bakos and co-workers' value of 0.422+/-0.014 R_J (4.73+/-0.16 R_earth). Our values confirm that HAT-P-11b is very similar to GJ 436b (the only other known transiting super Neptune) in radius and other bulk properties.Comment: accepted to ApJ Letters, 11 pages, 2 figures (see Dittmann et al. 2009 ApJ 699 L48-L51

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

SummaryMitochondrial fusion and division play important roles in the regulation of apoptosis. Mitochondrial fusion proteins attenuate apoptosis by inhibiting release of cytochrome c from mitochondria, in part by controlling cristae structures. Mitochondrial division promotes apoptosis by an unknown mechanism. We addressed how division proteins regulate apoptosis using inhibitors of mitochondrial division identified in a chemical screen. The most efficacious inhibitor, mdivi-1 (for mitochondrial division inhibitor) attenuates mitochondrial division in yeast and mammalian cells by selectively inhibiting the mitochondrial division dynamin. In cells, mdivi-1 retards apoptosis by inhibiting mitochondrial outer membrane permeabilization. In vitro, mdivi-1 potently blocks Bid-activated Bax/Bak-dependent cytochrome c release from mitochondria. These data indicate the mitochondrial division dynamin directly regulates mitochondrial outer membrane permeabilization independent of Drp1-mediated division. Our findings raise the interesting possibility that mdivi-1 represents a class of therapeutics for stroke, myocardial infarction, and neurodegenerative diseases

Unraveling L_{n,k}: Grassmannian Kinematics

It was recently proposed that the leading singularities of the S-Matrix of N = 4 super Yang-Mills theory arise as the residues of a contour integral over a Grassmannian manifold, with space-time locality encoded through residue theorems generalizing Cauchy's theorem to more than one variable. We provide a method to identify the residue corresponding to any leading singularity, and we carry this out very explicitly for all leading singularities at tree level and one-loop. We also give several examples at higher loops, including all generic two-loop leading singularities and an interesting four-loop object. As a special case we consider a 12-pt N^4MHV leading singularity at two loops that has a new kinematic structure involving double square roots. Our analysis results in a simple picture for how the topological structure of loop graphs is reflected in various substructures within the Grassmannian.Comment: 26+11 page

The COSMOS AGN Spectroscopic Survey I: XMM Counterparts

We present optical spectroscopy for an X-ray and optical flux-limited sample of 677 XMM-Newton selected targets covering the 2 deg^2 COSMOS field, with a yield of 485 high-confidence redshifts. The majority of the spectra were obtained over three seasons (2005-2007) with the IMACS instrument on the Magellan (Baade) telescope. We also include in the sample previously published Sloan Digital Sky Survey spectra and supplemental observations with MMT/Hectospec. We detail the observations and classification analyses. The survey is 90% complete to flux limits of f_{0.5-10 keV}>8 x 10^-16 erg cm^-2 s^-1 and i_AB+<22, where over 90% of targets have high-confidence redshifts. Making simple corrections for incompleteness due to redshift and spectral type allows for a description of the complete population to $i_AB+<23. The corrected sample includes 57% broad emission line (Type 1, unobscured) AGN at 0.13<z<4.26, 25% narrow emission line (Type 2, obscured) AGN at 0.07<z<1.29, and 18% absorption line (host-dominated, obscured) AGN at 0<z<1.22 (excluding the stars that made up 4% of the X-ray targets). We show that the survey's limits in X-ray and optical flux include nearly all X-ray AGN (defined by L_{0.5-10 keV}>3 x 10^42 erg s^-1) to z<1, of both optically obscured and unobscured types. We find statistically significant evidence that the obscured to unobscured AGN ratio at z<1 increases with redshift and decreases with luminosity.Comment: Accepted for publication in the ApJ. 31 pages, 17 figures. Table 2 is available on reques

Attentional Processing in C57BL/6J Mice Exposed to Developmental Vitamin D Deficiency

Epidemiological evidence suggests that Developmental Vitamin D (DVD) deficiency is associated with an increased risk of schizophrenia. DVD deficiency in mice is associated with altered behaviour, however there has been no detailed investigation of cognitive behaviours in DVD-deficient mice. The aim of this study was to determine the effect of DVD deficiency on a range of cognitive tasks assessing attentional processing in C57BL/6J mice. DVD deficiency was established by feeding female C57BL/6J mice a vitamin D-deficient diet from four weeks of age. After six weeks on the diet, vitamin D-deficient and control females were mated with vitamin D-normal males and upon birth of the pups, all dams were returned to a diet containing vitamin D. The adult offspring were tested on a range of cognitive behavioural tests, including the five-choice serial reaction task (5C-SRT) and five-choice continuous performance test (5C-CPT), as well as latent inhibition using a fear conditioning paradigm. DVD deficiency was not associated with altered attentional performance on the 5C-SRT. In the 5C-CPT DVD-deficient male mice exhibited an impairment in inhibiting repetitive responses by making more perseverative responses, with no changes in premature or false alarm responding. DVD deficiency did not affect the acquisition or retention of cued fear conditioning, nor did it affect the expression of latent inhibition using a fear conditioning paradigm. DVD-deficient mice exhibited no major impairments in any of the cognitive domains tested. However, impairments in perseverative responding in DVD-deficient mice may indicate that these animals have specific alterations in systems governing compulsive or reward-seeking behaviour

Standalone vertex finding in the ATLAS muon spectrometer

A dedicated reconstruction algorithm to find decay vertices in the ATLAS muon spectrometer is presented. The algorithm searches the region just upstream of or inside the muon spectrometer volume for multi-particle vertices that originate from the decay of particles with long decay paths. The performance of the algorithm is evaluated using both a sample of simulated Higgs boson events, in which the Higgs boson decays to long-lived neutral particles that in turn decay to bbar b final states, and pp collision data at √s = 7 TeV collected with the ATLAS detector at the LHC during 2011

Measurements of Higgs boson production and couplings in diboson final states with the ATLAS detector at the LHC

Measurements are presented of production properties and couplings of the recently discovered Higgs boson using the decays into boson pairs, H →γ γ, H → Z Z∗ →4l and H →W W∗ →lνlν. The results are based on the complete pp collision data sample recorded by the ATLAS experiment at the CERN Large Hadron Collider at centre-of-mass energies of √s = 7 TeV and √s = 8 TeV, corresponding to an integrated luminosity of about 25 fb−1. Evidence for Higgs boson production through vector-boson fusion is reported. Results of combined fits probing Higgs boson couplings to fermions and bosons, as well as anomalous contributions to loop-induced production and decay modes, are presented. All measurements are consistent with expectations for the Standard Model Higgs boson

Expected Performance of the ATLAS Experiment - Detector, Trigger and Physics

A detailed study is presented of the expected performance of the ATLAS detector. The reconstruction of tracks, leptons, photons, missing energy and jets is investigated, together with the performance of b-tagging and the trigger. The physics potential for a variety of interesting physics processes, within the Standard Model and beyond, is examined. The study comprises a series of notes based on simulations of the detector and physics processes, with particular emphasis given to the data expected from the first years of operation of the LHC at CERN