Qualidade de carcaça de novilhos terminados com dietas contendo levedura, monensina e associação de ambos aditivos

To evaluate the effects of the supplementation of feed additives on carcass quality in beef cattle, 72 Nellore steers (339.5kg, 20-month old) were feedlot finished and fed for 91 days one of the following diets: 1) control with no additives; or added of 2) live yeast culture; 3) monensin; or 4) the association of both additives. After slaughter, renal, pelvic, and inguinal fat and hot carcass weights were recorded and carcass was split into muscle, bone, and trimmable fat. Carcass Longissimus muscle area and subcutaneous fat thickness at the 12th rib were measured and steaks of Longisimus muscle were taken to determine meat color, shear force, drip, and cooking losses. Yeast increased carcass dressing percentage but there were no effects on hot carcass weight, Longissimus area, subcutaneous fat thickness, percentage and weight of retail cut yield and trimmings. Feed additives had no effect on carcass pH, meat color, fat content, shear force, and drip losses. Supplementation of yeast, monensin or the association of both additives had no important effects on carcass traits and on meat quality of feedlot finished steers.Avaliaram-se os efeitos da suplementação de aditivos alimentares sobre a qualidade de carcaça em bovinos de corte. Usaram-se 72 novilhos Nelore com média de peso de 339,5kg e 20 meses de idade, terminados em confinamento e alimentados por 91 dias com uma das quatro dietas: 1) dieta controle sem aditivos, ou com a adição de 2) leveduras vivas, 3) monensina ou 4) associação entre ambos aditivos. Após o abate, os pesos da gordura renal, pélvica e inguinal e da carcaça foram medidos e a carcaça dividida em músculos, ossos e aparas. Foram mensurados a área de olho de lombo e a espessura de gordura subcutânea sobre o músculo Longissimus na região da 12ª costela e foram obtidos bifes para a determinação da cor, força de cisalhamento e perdas por cocção e cozimento da carne. A levedura aumentou o rendimento de carcaça, mas não houve efeito dos tratamentos sobre o peso de carcaça, porção comestível e aparas. Os aditivos não influenciaram o pH da carcaça, a cor, a gordura intramuscular, a força de cisalhamento e as perdas por exsudação da carne. A suplementação, com levedura e com monensina em associação ou separadamente, não teve efeito importante sobre a qualidade da carcaça em novilhos terminados em confinamento.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP

On spin-1 massive particles coupled to a Chern-Simons field

We study spin one particles interacting through a Chern-Simons field. In the Born approximation, we calculate the two body scattering amplitude considering three possible ways to introduce the interaction: (a) a Proca like model minimally coupled to a Chern-Simons field, (b) the model obtained from (a) by replacing the Proca's mass by a Chern-Simons term and (c) a complex Maxwell-Chern-Simons model minimally coupled to a Chern-Simons field. In the low energy regime the results show similarities with the Aharonov-Bohm scattering for spin 1/2 particles. We discuss the one loop renormalization program for the Proca's model. In spite of the bad ultraviolet behavior of the matter field propagator, we show that, up to one loop the model is power counting renormalizable thanks to the Ward identities satisfied by the interaction vertices.Comment: 14 pages, 5 figures, revte

An activating mutation in the CRHR1 gene is rarely associated with pituitary-dependent hyperadrenocorticism in poodles

OBJECTIVES: Pituitary-dependent hyperadrenocorticism is the most common cause of naturally occurring hypercortisolism in dogs. CRHR1 expression in human and dog corticotrophinomas suggested that this gene affects pituitary tumorigenesis. The present study aimed to investigate mutations in the CRHR1 coding region in poodles with pituitary-dependent hyperadrenocorticism. METHODS: Fifty poodles with pituitary-dependent hyperadrenocorticism and 50 healthy poodles were studied. Genomic DNA was amplified by PCR and analyzed by Sanger sequencing. RESULTS: The novel CRHR1 p.V97M mutation was identified in one dog. This valine residue, located in the amino-terminal extracellular domain, exhibits high affinity for its corticotropin-releasing hormone (CRH) ligand. Bioinformatic analysis revealed structural rearrangements in the mutant protein, with a 17% increase in the surface binding affinity between CRHR1 and CRH. In vitro functional studies showed that mutant CRHR1 induced higher ACTH secretion than the wild type after stimulation with human CRH. CONCLUSION: These results suggest that germline activating mutations in CRHR1 may be a rare cause of pituitary hyperadrenocorticism in poodles

Functional Integral Construction of the Thirring model: axioms verification and massless limit

We construct a QFT for the Thirring model for any value of the mass in a functional integral approach, by proving that a set of Grassmann integrals converges, as the cutoffs are removed and for a proper choice of the bare parameters, to a set of Schwinger functions verifying the Osterwalder-Schrader axioms. The corresponding Ward Identities have anomalies which are not linear in the coupling and which violate the anomaly non-renormalization property. Additional anomalies are present in the closed equation for the interacting propagator, obtained by combining a Schwinger-Dyson equation with Ward Identities.Comment: 55 pages, 9 figure

Controlled release strategies for bone, cartilage, and osteochondral engineering: part I: recapitulation of native tissue healing and variables for the design of delivery systems

The potential of growth factors to stimulate tissue healing through the enhancement of cell proliferation, migration, and differentiation is undeniable. However, critical parameters on the design of adequate carriers, such as uncontrolled spatiotemporal presence of bioactive factors, inadequate release profiles, and supraphysiological dosages of growth factors, have impaired the translation of these systems onto clinical practice. This review describes the healing cascades for bone, cartilage, and osteochondral interface, highlighting the role of specific growth factors for triggering the reactions leading to tissue regeneration. Critical criteria on the design of carriersfor controlled release of bioactive factors are also reported, focusing on the need to provide a spatiotemporal control over the delivery and presentation of these molecules.The authors thank Fundacao para a Ciencia e Tecnologia for V.E.Santo's PhD grant (SFRH/BD/39486/2007). This work was carried out under the scope of the European FP7 Project Find and Bind (NMP4-SL-2009-229292) and Project MIT/ECE/0047/2009

Correlations of visual scores, carcass traits, feed efficiency and retail product yield in Nellore cattle

The growing use of visual scores (VS) and ultrasound (US) for carcass evaluation in breeding programs, calls for a knowledge of the relationships between these traits and other relevant characteristics, such as feed efficiency and production of commercial cuts. The objective of this study was to evaluate correlations between body visual scores and carcass traits identified by ultrasound (US) and feed efficiency (FE), carcass weight (HCW), dressing percentage (DP) and retail product yield (RPY) in beef cattle. Nellore cattle (male), 42 non-castrated [NCAST] and 44 castrated [CAST]) were evaluated by both VS and US, at the postweaning (15-month old) and finishing phases (21-month old). Visual scores of conformation (C), precocity (P) and muscling (M) were assessed and the backfat thickness (UBFT), rump fat thickness (URFT) and ribeye area (UREA) were measured by ultrasound. Gain-to-feed (G:F) ratio and residual feed intake (RFI) were measured in feedlot. Hot carcass weight, DP and RPY were determined at harvest. Non-castrated cattle had greater HCW and RPY but lower UBFT and URFT than CAST. Postweaning VS and US were poorly correlated with FE in both sexual conditions. Finishing VS were negatively correlated with G:F in CAST and finishing URFT was negatively correlated with RPY in NCAST. The relationship of VS and US with feed efficiency and meat yield is affected by age at the date of evaluation and by castration. Feed efficiency is not related to the yield of meat cuts in Nellore cattl

The Science of Sungrazers, Sunskirters, and Other Near-Sun Comets

This review addresses our current understanding of comets that venture close to the Sun, and are hence exposed to much more extreme conditions than comets that are typically studied from Earth. The extreme solar heating and plasma environments that these objects encounter change many aspects of their behaviour, thus yielding valuable information on both the comets themselves that complements other data we have on primitive solar system bodies, as well as on the near-solar environment which they traverse. We propose clear definitions for these comets: We use the term near-Sun comets to encompass all objects that pass sunward of the perihelion distance of planet Mercury (0.307 AU). Sunskirters are defined as objects that pass within 33 solar radii of the Sun’s centre, equal to half of Mercury’s perihelion distance, and the commonly-used phrase sungrazers to be objects that reach perihelion within 3.45 solar radii, i.e. the fluid Roche limit. Finally, comets with orbits that intersect the solar photosphere are termed sundivers. We summarize past studies of these objects, as well as the instruments and facilities used to study them, including space-based platforms that have led to a recent revolution in the quantity and quality of relevant observations. Relevant comet populations are described, including the Kreutz, Marsden, Kracht, and Meyer groups, near-Sun asteroids, and a brief discussion of their origins. The importance of light curves and the clues they provide on cometary composition are emphasized, together with what information has been gleaned about nucleus parameters, including the sizes and masses of objects and their families, and their tensile strengths. The physical processes occurring at these objects are considered in some detail, including the disruption of nuclei, sublimation, and ionisation, and we consider the mass, momentum, and energy loss of comets in the corona and those that venture to lower altitudes. The different components of comae and tails are described, including dust, neutral and ionised gases, their chemical reactions, and their contributions to the near-Sun environment. Comet-solar wind interactions are discussed, including the use of comets as probes of solar wind and coronal conditions in their vicinities. We address the relevance of work on comets near the Sun to similar objects orbiting other stars, and conclude with a discussion of future directions for the field and the planned ground- and space-based facilities that will allow us to address those science topics

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results