34 research outputs found
The nitrogen problem of epiphytic lichens â a synthesis
Der starke Anstieg von nitrophytischen Flechten wĂ€hrend der letzten 15 Jahren in landwirtschaftlich genutzten und stĂ€dtischen Bereichen hat die Frage aufgeworfen, welche Stickstoffverbindung dafĂŒr verantwortlich sind, welche physiologischen Probleme diese machen, wo diese herkommen, welche Auswirkungen sie auf die Flechten haben, was mit dem Stickstoff in den Flechten passiert, wie sich Feinstaub und trockene Deposition auswirken und wieso Nitrophyten auch in unbelasteten Gebieten dominieren. Nach den Ergebnissen zahlreicher Einzelstudien, die hier mit neuen Daten ergĂ€nzt werden, ist Ammoniak die relevante Stickstoffquelle. Dieser wird als Ammoniumnitrat speziell in Form von trockener Deposition von den Flechten aufgenommen. Da Ammoniumnitrat ein Salz ist, haben Nitrophyten höhere osmotische Werte, weswegen sie in belasteten Gebieten konkurrenzkrĂ€ftiger sind. Dies erlaubt Nitrophyten gleichzeitig die Existenz in Trockengebieten auch ohne Stickstoffemissionen, weswegen sie nicht unbedingt Stickstoffzeiger sondern auch Trockenzeiger sind. Der anfallende Stickstoff wird in Form von AminosĂ€uren in der Flechte passiv gespeichert, weswegen Nitrophyten nicht nitrophil sondern nitrotolerant, halotolerant und xerophytisch sind. Die momentane Temperaturerhöhung und die damit verbundene erhöhte Verdunstung sowie die Zunahme trockener Deposition (Feinstaubbelastung) fĂŒhren zur Zeit trotz sinkender Gesamtstickstoffbelastung zu einem weiteren Anstieg der nitrophytischen Flechten.The strong increase of nitrophytic lichens in Central Europe during the past fifteen years in urban regions and regions with intensive agriculture poses the question, which nitrogen compounds are responsible, where they come from, which effects they have on lichens, what happens with the nitrogen in lichens, how particulate matter and dry deposition influence lichens und why nitrophytic lichens dominate also in regions with no or low nitrogen emissions. According to several studies, which are complete by new data, ammonia is the relevant source of nitrogen. It is taken up by lichens as ammoniumnitrate as dry deposition. Ammoniumnitrate, however, is a salt. Accordingly nitrophytic lichens have higher osmotic values. This enables nitrophytic lichens to survive in drier regions as compared with other epiphytic lichens, where they are more competitive, even without nitrogen emissions. Therefore nitrophytic lichens are not nitrophilous but halotolerant and xerophytic. The present increase of temperatures, which raises the evaporation, and the increase of dry deposition (particulate matter) cause an increase of nitrophytic lichens in spite of decrease total nitrogen emissions
InclusiĂłn social en el proceso REDD en el PerĂș: una perspectiva de gobernanza en mĂșltiples niveles
REDD is one of the latest additions to a series of incentive-based mechanisms for reducing carbon emissions. Although international negotiations have not eliminated uncertainties regarding its social, economic and political implications, many developing and emerging countries have begun to engage in REDD. Peru, the country with the worldâs fourth largest tropical forest area has good reason to participate in REDD: deforestation currently causes about half of Peruâs annual greenhouse gas (GHG) emissions.In the last eight years, public and private actors across scales have undertaken various initiatives â resulting in a multi-level governance patchwork with top-down and bottom-up processes and institutions that operate in parallel. Our study addresses this hotchpotch and its challenges to key aspects of good governance.First, we mapped Peruâs complex REDD governance architecture and the role of major stakeholders. At the national level, we scrutinized Peruâs readiness preparation proposal (RâPP) and its plan for the Forest Investment Programme (FIP), the REDD stakeholders roundtable, decentralization of forest-related competencies, and the dif cult birth of new national laws on forests and full, prior and informed consent (FPIC). At the regional level, the study focuses on the two key regions of San MartĂn and Madre de Dios, mapping their most important forest policies and forms of stakeholder self-organization. Finally, we investigated four pilot projects with very different legal status that re ect the broad scope of REDD projects in Peru.Second, we conducted a stakeholder-based assessment of different dimensions of social inclusion in Peruvian REDD governance. Despite the exibility offered by the numerous processes, we found areas that need improvement. In some cases these are merely teething problems; others are deeply rooted in socio-economic imbalances and political culture. The challenges include: the insuf cient nancial, technical and human capacities of ministries and regional governments; a legitimacy gap due to the dominance of certain NGOs and companies; information and participation asymmetries of forest users in REDD projects, which can cause social tension; insuf cient consideration of informal settlers; and insecurity regarding the distribution of REDD revenues among investors, NGOs and forest users
Characterization of volatile metabolites formed by molds on barley by mass and ion mobility spectrometry
The contamination of barley by molds on the field or in storage leads to the spoilage of grain and the production of mycotoxins, which causes major economic losses in malting facilities and breweries. Therefore, onâsite detection of hidden fungus contaminations in grain storages based on the detection of volatile marker compounds is of high interest. In this work, the volatile metabolites of 10 different fungus species are identified by gas chromatography (GC) combined with two complementary mass spectrometric methods, namely, electron impact (EI) and chemical ionization at atmospheric pressure (APCI)âmass spectrometry (MS). The APCI source utilizes soft Xâradiation, which enables the selective protonation of the volatile metabolites largely without side reactions. Nearly 80 volatile or semivolatile compounds from different substance classes, namely, alcohols, aldehydes, ketones, carboxylic acids, esters, substituted aromatic compounds, alkenes, terpenes, oxidized terpenes, sesquiterpenes, and oxidized sesquiterpenes, could be identified. The profiles of volatile and semivolatile metabolites of the different fungus species are characteristic of them and allow their safe differentiation. The application of the same GC parameters and APCI source allows a simple method transfer from MS to ion mobility spectrometry (IMS), which permits onâsite analyses of grain stores. Characterization of IMS yields limits of detection very similar to those of APCIâMS. Accordingly, more than 90% of the volatile metabolites found by APCIâMS were also detected in IMS. In addition to different fungus genera, different species of one fungus genus could also be differentiated by GCâIMS.BMEL, 2814801811, Verbundprojekt: Rohstoffscreening mit spektral-optischen Verfahren bei der Getreidelagerung (OptiScreen) - Teilprojekt
The genomes of two key bumblebee species with primitive eusocial organization
Background: The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies. Bumblebees are also invaluable natural and agricultural pollinators, and there is widespread concern over recent population declines in some species. High-quality genomic data will inform key aspects of bumblebee biology, including susceptibility to implicated population viability threats. Results: We report the high quality draft genome sequences of Bombus terrestris and Bombus impatiens, two ecologically dominant bumblebees and widely utilized study species. Comparing these new genomes to those of the highly eusocial honeybee Apis mellifera and other Hymenoptera, we identify deeply conserved similarities, as well as novelties key to the biology of these organisms. Some honeybee genome features thought to underpin advanced eusociality are also present in bumblebees, indicating an earlier evolution in the bee lineage. Xenobiotic detoxification and immune genes are similarly depauperate in bumblebees and honeybees, and multiple categories of genes linked to social organization, including development and behavior, show high conservation. Key differences identified include a bias in bumblebee chemoreception towards gustation from olfaction, and striking differences in microRNAs, potentially responsible for gene regulation underlying social and other traits. Conclusions: These two bumblebee genomes provide a foundation for post-genomic research on these key pollinators and insect societies. Overall, gene repertoires suggest that the route to advanced eusociality in bees was mediated by many small changes in many genes and processes, and not by notable expansion or depauperation
Which chronic diseases and disease combinations are specific to multimorbidity in the elderly? Results of a claims data based cross-sectional study in Germany
<p>Abstract</p> <p>Background</p> <p>Growing interest in multimorbidity is observable in industrialized countries. For Germany, the increasing attention still goes still hand in hand with a small number of studies on multimorbidity. The authors report the first results of a cross-sectional study on a large sample of policy holders (n = 123,224) of a statutory health insurance company operating nationwide. This is the first comprehensive study addressing multimorbidity on the basis of German claims data. The main research question was to find out which chronic diseases and disease combinations are specific to multimorbidity in the elderly.</p> <p>Methods</p> <p>The study is based on the claims data of all insured policy holders aged 65 and older (n = 123,224). Adjustment for age and gender was performed for the German population in 2004. A person was defined as multimorbid if she/he had at least 3 diagnoses out of a list of 46 chronic conditions in three or more quarters within the one-year observation period. Prevalences and risk-ratios were calculated for the multimorbid and non-multimorbid samples in order to identify diagnoses more specific to multimorbidity and to detect excess prevalences of multimorbidity patterns.</p> <p>Results</p> <p>62% of the sample was multimorbid. Women in general and patients receiving statutory nursing care due to disability are overrepresented in the multimorbid sample. Out of the possible 15,180 combinations of three chronic conditions, 15,024 (99%) were found in the database. Regardless of this wide variety of combinations, the most prevalent individual chronic conditions do also dominate the combinations: Triads of the six most prevalent individual chronic conditions (hypertension, lipid metabolism disorders, chronic low back pain, diabetes mellitus, osteoarthritis and chronic ischemic heart disease) span the disease spectrum of 42% of the multimorbid sample. Gender differences were minor. Observed-to-expected ratios were highest when purine/pyrimidine metabolism disorders/gout and osteoarthritis were part of the multimorbidity patterns.</p> <p>Conclusions</p> <p>The above list of dominating chronic conditions and their combinations could present a pragmatic start for the development of needed guidelines related to multimorbidity.</p
Progressive skin fibrosis is associated with a decline in lung function and worse survival in patients with diffuse cutaneous systemic sclerosis in the European Scleroderma Trials and Research (EUSTAR) cohort.
Objectives To determine whether progressive skin fibrosis is associated with visceral organ progression and mortality during follow-up in patients with diffuse cutaneous systemic sclerosis (dcSSc). Methods We evaluated patients from the European Scleroderma Trials and Research database with dcSSc, baseline modified Rodnan skin score (mRSS) â„7, valid mRSS at 12±3 months after baseline and â„1 annual follow-up visit. Progressive skin fibrosis was defined as an increase in mRSS >5 and â„25% from baseline to 12±3 months. Outcomes were pulmonary, cardiovascular and renal progression, and all-cause death. Associations between skin progression and outcomes were evaluated by Kaplan-Meier survival analysis and multivariable Cox regression. Results Of 1021 included patients, 78 (7.6%) had progressive skin fibrosis (skin progressors). Median follow-up was 3.4 years. Survival analyses indicated that skin progressors had a significantly higher probability of FVC decline â„10% (53.6% vs 34.4%; p<0.001) and all-cause death (15.4% vs 7.3%; p=0.003) than non-progressors. These significant associations were also found in subgroup analyses of patients with either low baseline mRSS (â€22/51) or short disease duration (â€15 months). In multivariable analyses, skin progression within 1 year was independently associated with FVC decline â„10% (HR 1.79, 95% CI 1.20 to 2.65) and all-cause death (HR 2.58, 95% CI 1.31 to 5.09). Conclusions Progressive skin fibrosis within 1 year is associated with decline in lung function and worse survival in dcSSc during follow-up. These results confirm mRSS as a surrogate marker in dcSSc, which will be helpful for cohort enrichment in future trials and risk stratification in clinical practice
Finishing the euchromatic sequence of the human genome
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers âŒ99% of the euchromatic genome and is accurate to an error rate of âŒ1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Microwave spectro-polarimetry of matter and radiation across space and time
From Springer Nature via Jisc Publications RouterHistory: received 2020-07-29, accepted 2021-03-02, registration 2021-03-03, pub-print 2021-06, pub-electronic 2021-07-03, online 2021-07-03Publication status: PublishedAbstract: This paper discusses the science case for a sensitive spectro-polarimetric survey of the microwave sky. Such a survey would provide a tomographic and dynamic census of the three-dimensional distribution of hot gas, velocity flows, early metals, dust, and mass distribution in the entire Hubble volume, exploit CMB temperature and polarisation anisotropies down to fundamental limits, and track energy injection and absorption into the radiation background across cosmic times by measuring spectral distortions of the CMB blackbody emission. In addition to its exceptional capability for cosmology and fundamental physics, such a survey would provide an unprecedented view of microwave emissions at sub-arcminute to few-arcminute angular resolution in hundreds of frequency channels, a data set that would be of immense legacy value for many branches of astrophysics. We propose that this survey be carried out with a large space mission featuring a broad-band polarised imager and a moderate resolution spectro-imager at the focus of a 3.5 m aperture telescope actively cooled to about 8K, complemented with absolutely-calibrated Fourier Transform Spectrometer modules observing at degree-scale angular resolution in the 10â2000 GHz frequency range. We propose two observing modes: a survey mode to map the entire sky as well as a few selected wide fields, and an observatory mode for deeper observations of regions of specific interest
Reducing Emissions from Deforestation and Degradation in Peru: a challenge to social inclusion and multi-level governance
REDD is one of the latest additions to a series of incentive-based mechanisms for reducing carbon emissions. Although international negotiations have not eliminated uncertainties regarding its social, economic and political implications, many developing and emerging countries have begun to engage in REDD. Peru, the country with the worldâs fourth largest tropical forest area has good reason to participate in REDD: deforestation currently causes about half of Peruâs annual greenhouse gas (GHG) emissions.In the last eight years, public and private actors across scales have undertaken various initiatives â resulting in a multi-level governance patchwork with top-down and bottom-up processes and institutions that operate in parallel. Our study addresses this hotchpotch and its challenges to key aspects of good governance.First, we mapped Peruâs complex REDD governance architecture and the role of major stakeholders. At the national level, we scrutinized Peruâs readiness preparation proposal (RâPP) and its plan for the Forest Investment Programme (FIP), the REDD stakeholders roundtable, decentralization of forest-related competencies, and the dif cult birth of new national laws on forests and full, prior and informed consent (FPIC). At the regional level, the study focuses on the two key regions of San MartĂn and Madre de Dios, mapping their most important forest policies and forms of stakeholder self- organization. Finally, we investigated four pilot projects with very different legal status that re ect the broad scope of REDD projects in Peru.Second, we conducted a stakeholder-based assessment of different dimensions of social inclusion in Peruvian REDD governance. Despite the exibility offered by the numerous processes, we found areas that need improvement. In some cases these are merely teething problems; others are deeply rooted in socio-economic imbalances and political culture. The challenges include: the insuf cient nancial, technical and human capacities of ministries and regional governments; a legitimacy gap due to the dominance of certain NGOs and companies; information and participation asymmetries of forest users in REDD projects, which can cause social tension; insuf cient consideration of informal settlers; and insecurity regarding the distribution of REDD revenues among investors, NGOs and forest users.Third, we introduce and discuss options for addressing some of these challenges, including:âą Streamlining REDD processes with policies from other sectors such as agriculture and mining, and improving spatial planning;âą Formalizing channels of communication and consultation to ensure fair and equal opportunities for exchanges between civil society and the ministries;âą Establishing an independent entity as part of a multi-stakeholder safeguard information system (SIS) that will frequently provide forest users with in-depth information about REDD processes and help users to develop their own ideas about REDD;âą Integrating forest users â not just as bene ciaries but rather as co-implementers of REDD projects;âą Encompassing push and pull factors, for example, through a levy that channels a portion of REDD revenues towards eradicating poverty in the Andean highlands in an effort to stem migration into forested areas.REDD can only be as socially inclusive as the political, legal and social systems in which it is implemented. In Peru, this implies enhancing the overarching policies of social inclusion in the country, disentangling land titles and their governance, and improving mechanisms for veri cation and enforcement