139 research outputs found
Crossing the Educational Rubicon without the TAH: Collaboration among University and Secondary-Level History Educators
In April 2011, Congress slashed funding for a majority of programs tied to education. Several programs related to professional development for teachers did not survive. While cut severely—from 46 million (a loss of $73 million or 61% of its funding)—Teaching American History (TAH) grants lived, albeit by their fingertips, another day. Yet, given the economic challenges the United States faces and what appear to be prevailing attitudes in regard to social services and teacher development, it has become clear that history educators cannot rely on federal funding to support efforts to improve the teaching of history.
Nevertheless, meaningful collaboration among K-12 teachers and academic and public historians continues to be vital. This essay describes in detail a current collaborative relationship between a history department and high school in western Michigan. Focusing specifically on four levels of interlocking benefits of collaboration—benefits for high school teachers, for teaching candidates, for high school students, and for historians—the essay documents the strengths of this collaborative effort and notes areas where purposeful concentration and improvement might benefit all parties. Significantly, the relationship examined here, between the history department at Western Michigan University (WMU) and Portage Central High School (PCHS), developed without a promise or expectation of financial incentives. It demonstrates that collaboration, while challenging, can survive in the twenty-first century without funding from a TAH grant
Low False-Positive Rate of Kepler Candidates Estimated From A Combination Of Spitzer And Follow-Up Observations
(Abridged) NASA's Kepler mission has provided several thousand transiting
planet candidates, yet only a small subset have been confirmed as true planets.
Therefore, the most fundamental question about these candidates is the fraction
of bona fide planets. Estimating the rate of false positives of the overall
Kepler sample is necessary to derive the planet occurrence rate. We present the
results from two large observational campaigns that were conducted with the
Spitzer telescope during the the Kepler mission. These observations are
dedicated to estimating the false positive rate (FPR) amongst the Kepler
candidates. We select a sub-sample of 51 candidates, spanning wide ranges in
stellar, orbital and planetary parameter space, and we observe their transits
with Spitzer at 4.5 microns. We use these observations to measures the
candidate's transit depths and infrared magnitudes. A bandpass-dependent depth
alerts us to the potential presence of a blending star that could be the source
of the observed eclipse: a false-positive scenario. For most of the candidates
(85%), the transit depths measured with Kepler are consistent with the depths
measured with Spitzer as expected for planetary objects, while we find that the
most discrepant measurements are due to the presence of unresolved stars that
dilute the photometry. The Spitzer constraints on their own yield FPRs between
5-40%, depending on the KOIs. By considering the population of the Kepler field
stars, and by combining follow-up observations (imaging) when available, we
find that the overall FPR of our sample is low. The measured upper limit on the
FPR of our sample is 8.8% at a confidence level of 3 sigma. This observational
result, which uses the achromatic property of planetary transit signals that is
not investigated by the Kepler observations, provides an independent indication
that Kepler's false positive rate is low.Comment: 33 pages, 16 figures, 3 tables; accepted for publication in ApJ on
February 7, 201
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The High-Energy Radiation Environment Around a 10 Gyr M Dwarf: Habitable at Last?
High levels of X-ray and UV activity on young M dwarfs may drive rapid
atmospheric escape on temperate, terrestrial planets orbiting within the liquid
water habitable zone. However, secondary atmospheres on planets orbiting older,
less active M dwarfs may be stable and present more promising candidates for
biomarker searches. We present new HST and Chandra observations of Barnard's
Star (GJ 699), a 10 Gyr old M3.5 dwarf, acquired as part of the Mega-MUSCLES
program. Despite the old age and long rotation period of Barnard's star, we
observe two FUV ( 5000s;
10 erg each) and one X-ray ( 10 erg) flares,
and estimate a high-energy flare duty cycle (defined here as the fraction of
the time the star is in a flare state) of 25\%. A 5 A - 10 m SED of
GJ 699 is created and used to evaluate the atmospheric stability of a
hypothetical, unmagnetized terrestrial planet in the habitable zone (
0.1 AU). Both thermal and non-thermal escape modeling indicate (1) the
stellar XUV flux does not lead to strong atmospheric escape:
atmospheric heating rates are comparable to periods of high solar activity on
modern Earth, and (2) the environment could drive the atmosphere into a
hydrodynamic loss regime at the observed flare duty cycle: sustained exposure
to the flare environment of GJ 699 results in the loss of 87 Earth
atmospheres Gyr through thermal processes and 3 Earth
atmospheres Gyr through ion loss processes, respectively. These results
suggest that if rocky planet atmospheres can survive the initial 5 Gyr
of high stellar activity, or if a second generation atmosphere can be formed or
acquired, the flare duty cycle may be the controlling stellar parameter for the
stability of Earth-like atmospheres around old M stars.Comment: Accepted to A
The macroecology of infectious diseases: a new perspective on global-scale drivers of pathogen distributions and impacts
© 2016 John Wiley & Sons Ltd/CNRS. Identifying drivers of infectious disease patterns and impacts at the broadest scales of organisation is one of the most crucial challenges for modern science, yet answers to many fundamental questions remain elusive. These include what factors commonly facilitate transmission of pathogens to novel host species, what drives variation in immune investment among host species, and more generally what drives global patterns of parasite diversity and distribution? Here we consider how the perspectives and tools of macroecology, a field that investigates patterns and processes at broad spatial, temporal and taxonomic scales, are expanding scientific understanding of global infectious disease ecology. In particular, emerging approaches are providing new insights about scaling properties across all living taxa, and new strategies for mapping pathogen biodiversity and infection risk. Ultimately, macroecology is establishing a framework to more accurately predict global patterns of infectious disease distribution and emergence
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Low False-Positive Rate of Kepler Candidates Estimated From a Combination of Spitzer and Follow-Up Observations
NASA’s Kepler mission has provided several thousand transiting planet candidates during the four years of its nominal mission, yet only a small subset of these candidates have been confirmed as true planets. Therefore, the most fundamental question about these candidates is the fraction of bona fide planets. Estimating the rate of false positives of the overall Kepler sample is necessary to derive the planet occurrence rate. We present the results from two large observational campaigns that were conducted with the Spitzer Space Telescope during the the Kepler mission. These observations are dedicated to estimating the false positive rate (FPR) amongst the Kepler candidates. We select a sub-sample of 51 candidates, spanning wide ranges in stellar, orbital and planetary parameter space, and we observe their transits with Spitzer at 4.5 µm. We use these observations to measures the candidate’s transit depths and infrared magnitudes. An authentic planet produces an achromatic transit depth (neglecting the modest effect of limb darkening). Conversely a bandpass-dependent depth alerts us to the potential presence of a blending star that could be the source of the observed eclipse: a false-positive scenario. For most of the candidates (85%), the transit depths measured with Kepler are consistent with the transit depths measured with Spitzer as expected for planetary objects, while we find that the most discrepant measurements are due to the presence of unresolved stars that dilute the photometry. The Spitzer constraints on their own yield FPRs between 5-40%, depending on the KOIs. By considering the population of the Kepler field stars, and by combining follow-up observations (imaging) when available, we find that the overall FPR of our sample is low. The measured upper limit on the FPR of our sample is 8.8% at a confidence level of 3σ. This observational result, which uses the achromatic property of planetary transit signals that is not investigated by the Kepler observations, provides an independent indication that Kepler ’s false positive rate is low.Astronom
The Long-Baseline Neutrino Experiment: Exploring Fundamental Symmetries of the Universe
The preponderance of matter over antimatter in the early Universe, the
dynamics of the supernova bursts that produced the heavy elements necessary for
life and whether protons eventually decay --- these mysteries at the forefront
of particle physics and astrophysics are key to understanding the early
evolution of our Universe, its current state and its eventual fate. The
Long-Baseline Neutrino Experiment (LBNE) represents an extensively developed
plan for a world-class experiment dedicated to addressing these questions. LBNE
is conceived around three central components: (1) a new, high-intensity
neutrino source generated from a megawatt-class proton accelerator at Fermi
National Accelerator Laboratory, (2) a near neutrino detector just downstream
of the source, and (3) a massive liquid argon time-projection chamber deployed
as a far detector deep underground at the Sanford Underground Research
Facility. This facility, located at the site of the former Homestake Mine in
Lead, South Dakota, is approximately 1,300 km from the neutrino source at
Fermilab -- a distance (baseline) that delivers optimal sensitivity to neutrino
charge-parity symmetry violation and mass ordering effects. This ambitious yet
cost-effective design incorporates scalability and flexibility and can
accommodate a variety of upgrades and contributions. With its exceptional
combination of experimental configuration, technical capabilities, and
potential for transformative discoveries, LBNE promises to be a vital facility
for the field of particle physics worldwide, providing physicists from around
the globe with opportunities to collaborate in a twenty to thirty year program
of exciting science. In this document we provide a comprehensive overview of
LBNE's scientific objectives, its place in the landscape of neutrino physics
worldwide, the technologies it will incorporate and the capabilities it will
possess.Comment: Major update of previous version. This is the reference document for
LBNE science program and current status. Chapters 1, 3, and 9 provide a
comprehensive overview of LBNE's scientific objectives, its place in the
landscape of neutrino physics worldwide, the technologies it will incorporate
and the capabilities it will possess. 288 pages, 116 figure
THE HOT-JUPITER KEPLER-17b: DISCOVERY, OBLIQUITY FROM STROBOSCOPIC STARSPOTS, AND ATMOSPHERIC CHARACTERIZATION
This paper reports the discovery and characterization of the transiting hot giant exoplanet Kepler-17b. The planet has an orbital period of 1.486 days, and radial velocity measurements from the Hobby–Eberly Telescope show a Doppler signal of 419.5+13.3−15.6 m s−1. From a transit-based estimate of the host star's mean density, combined with an estimate of the stellar effective temperature Teff = 5630 ± 100 from high-resolution spectra, we infer a stellar host mass of 1.06 ± 0.07 M☉ and a stellar radius of 1.02 ± 0.03 R☉. We estimate the planet mass and radius to be MP = 2.45 ± 0.11 MJ and RP = 1.31 ± 0.02 RJ. The host star is active, with dark spots that are frequently occulted by the planet. The continuous monitoring of the star reveals a stellar rotation period of 11.89 days, eight times the planet's orbital period; this period ratio produces stroboscopic effects on the occulted starspots. The temporal pattern of these spot-crossing events shows that the planet's orbit is prograde and the star's obliquity is smaller than 15°. We detected planetary occultations of Kepler-17b with both the Kepler and Spitzer Space Telescopes. We use these observations to constrain the eccentricity, e, and find that it is consistent with a circular orbit (e < 0.011). The brightness temperatures of the planet's infrared bandpasses are T3.6 μm = 1880 ± 100 K and T4.5 μm = 1770 ± 150 K. We measure the optical geometric albedo Ag in the Kepler bandpass and find Ag = 0.10 ± 0.02. The observations are best described by atmospheric models for which most of the incident energy is re-radiated away from the day side
Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis
BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London
Vitamin D and Its Role During Pregnancy in Attaining Optimal Health of Mother and Fetus
Despite its discovery a hundred years ago, vitamin D has emerged as one of the most controversial nutrients and prohormones of the 21st century. Its role in calcium metabolism and bone health is undisputed but its role in immune function and long-term health is debated. There are clear indicators from in vitro and animal in vivo studies that point to vitamin D’s indisputable role in both innate and adaptive immunity; however, the translation of these findings to clinical practice, including the care of the pregnant woman, has not occurred. Until recently, there has been a paucity of data from randomized controlled trials to establish clear cut beneficial effects of vitamin D supplementation during pregnancy. An overview of vitamin metabolism, states of deficiency, and the results of recent clinical trials conducted in the U.S. are presented with an emphasis on what is known and what questions remain to be answered
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