191 research outputs found
Ï production in pâPb collisions at âsNN=8.16 TeV
Ï production in pâPb interactions is studied at the centre-of-mass energy per nucleonânucleon collision âsNN = 8.16 TeV with the ALICE detector at the CERN LHC. The measurement is performed reconstructing bottomonium resonances via their dimuon decay channel, in the centre-of-mass rapidity intervals 2.03 < ycms < 3.53 and â4.46 < ycms < â2.96, down to zero transverse momentum. In this work, results on the Ï(1S) production cross section as a function of rapidity and transverse momentum are presented. The corresponding nuclear modification factor shows a suppression of the Ï(1S) yields with respect to pp collisions, both at forward and backward rapidity. This suppression is stronger in the low transverse momentum region and shows no significant dependence on the centrality of the interactions. Furthermore, the Ï(2S) nuclear modification factor is evaluated, suggesting a suppression similar to that of the Ï(1S). A first measurement of the Ï(3S) has also been performed. Finally, results are compared with previous ALICE measurements in pâPb collisions at âsNN = 5.02 TeV and with theoretical calculations.publishedVersio
(Anti-)deuteron production in pp collisions at 1as=13TeV
The study of (anti-)deuteron production in pp collisions has proven to be a powerful tool to investigate the formation mechanism of loosely bound states in high-energy hadronic collisions. In this paper the production of (anti-)deuterons is studied as a function of the charged particle multiplicity in inelastic pp collisions at s=13 TeV using the ALICE experiment. Thanks to the large number of accumulated minimum bias events, it has been possible to measure (anti-)deuteron production in pp collisions up to the same charged particle multiplicity (d Nch/ d \u3b7 3c 26) as measured in p\u2013Pb collisions at similar centre-of-mass energies. Within the uncertainties, the deuteron yield in pp collisions resembles the one in p\u2013Pb interactions, suggesting a common formation mechanism behind the production of light nuclei in hadronic interactions. In this context the measurements are compared with the expectations of coalescence and statistical hadronisation models (SHM)
Multiplicity dependence of inclusive J/psi production at midrapidity in pp collisions at root s=13 TeV
Measurements of the inclusive J/psi yield as a function of charged-particle pseudorapidity density dN(ch)/d eta in pp collisions at root s = 13 TeV with ALICE at the LHC are reported. The J/psi meson yield is measured at midrapidity (vertical bar y vertical bar <0.9) in the dielectron channel, for events selected based on the charged-particle multiplicity at midrapidity (vertical bar eta vertical bar <1) and at forward rapidity (-3.7 <eta <-1.7 and 2.8 <eta <5.1); both observables are normalized to their corresponding averages in minimum bias events. The increase of the normalized J/psi yield with normalized dN(ch)/d eta is significantly stronger than linear and dependent on the transverse momentum. The data are compared to theoretical predictions, which describe the observed trends well, albeit not always quantitatively. (C) 2020 European Organization for Nuclear Research. Published by Elsevier B.V.Peer reviewe
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes.
GWAS have identified >200 risk loci for Inflammatory Bowel Disease (IBD). The majority of disease associations are known to be driven by regulatory variants. To identify the putative causative genes that are perturbed by these variants, we generate a large transcriptome data set (nine disease-relevant cell types) and identify 23,650 cis-eQTL. We show that these are determined by âŒ9720 regulatory modules, of which âŒ3000 operate in multiple tissues and âŒ970 on multiple genes. We identify regulatory modules that drive the disease association for 63 of the 200 risk loci, and show that these are enriched in multigenic modules. Based on these analyses, we resequence 45 of the corresponding 100 candidate genes in 6600 Crohn disease (CD) cases and 5500 controls, and show with burden tests that they include likely causative genes. Our analyses indicate that â„10-fold larger sample sizes will be required to demonstrate the causality of individual genes using this approach
Elliptic flow of charged particles at midrapidity relative to the spectator plane in PbâPb and XeâXe collisions
Measurements of the elliptic flow coefficient relative to the collision plane defined by the spectator neutrons v2{ SP} in collisions of Pb ions at center-of-mass energy per nucleonânucleon pair â 2.76 TeV and Xe ions at â sNN = sNN =5.44 TeV are reported. The results are presented for charged particles produced at midrapidity as a function of centrality and transverse momentum for the 5â70% and 0.2â6 GeV/c ranges, respectively. The ratio between v2{ SP} and the elliptic flow coefficient relative to the participant plane v2{4}, estimated using four-particle correlations, deviates by up to 20% from unity depending on centrality. This observation differs strongly from the magnitude of the corresponding eccentricity ratios predicted by the TRENTo and the elliptic power models of initial state fluctuations that are tuned to describe the participant plane anisotropies. The differences can be interpreted as a decorrelation of the neutron spectator plane and the reaction plane because of fragmentation of the remnants from the colliding nuclei, which points to an incompleteness of current models describing the initial state fluctuations. A significant transverse momentum dependence of the ratio v2{ SP}/v2{4} is observed in all but the most central collisions, which may help to understand whether momentum anisotropies at low and intermediate transverse momentum have a common origin in initial state f luctuations. The ratios of v2{ SP} and v2{4} to the corresponding initial state eccentricities for XeâXe and PbâPb collisions at similar initial entropy density show a difference of (7.0 ±0.9)%with an additional variation of +1.8% when including RHIC data in the TRENTo parameter extraction. These observations provide new experimental constraints for viscous effects in the hydrodynamic modeling of the expanding quarkâgluon plasma produced in heavy-ion collisions at the LHC
First measurement of Ωc0 production in pp collisions at s=13 TeV
The inclusive production of the charmâstrange baryon 0 c is measured for the first time via its hadronic â decay into âÏ+ at midrapidity (|y| <0.5) in protonâproton (pp) collisions at the centre-of-mass energy s =13 TeV with the ALICE detector at the LHC. The transverse momentum (pT) differential cross section multiplied by the branching ratio is presented in the interval 2 < pT < 12 GeV/c. The pT dependence of the 0 c-baryon production relative to the prompt D0-meson and to the prompt 0 c-baryon production is compared to various models that take different hadronisation mechanisms into consideration. In the measured pT interval, the ratio of the pT-integrated cross sections of 0 c and prompt + c baryons multiplied by the âÏ+ branching ratio is found to be larger by a factor of about 20 with a significance of about 4Ï when compared to e+eâ collisions
On the mechanism of single-stranded RNA synthesis by encephalomyocarditis virus replication complexes
Development and concentration efficiency study of enterprises innovation activity in real sector of economy
The relevance of the issue under investigation is reasoned by the fact that in growing global competition and expansion context, on the one hand, and economic constraints related to geopolitical tensions, on the other hand, a key factor in the enterprises competitiveness and priority positions achievement in the world market will be their transition to innovative production technologies and business. Topical and promising one in this case is to achieve competitive excellence, increase business efficiency through the innovations' projecting and commercialization. The paper purpose is to investigate the efficiency and specificity level of the ongoing innovation processes in the real sector of the economy as innovative transformations key segment and the basis for increasing the territory competitiveness. The leading method to the problem study is the method of systemic economic analysis, which allows revealing the essence, regularities, trends of the processes occurring at all levels of innovative transformations. To assess the innovative activity concentration and enterprises' innovative development nature, it is proposed to use analysis methods based on the cost efficiency evaluation, depending on the effect magnitude achieved as a result of innovations practical use, enabling to diagnose competitive and non-competitive producing groups, to determine the resource and innovation potential with strategy development further construction. The research materials can be used in innovative transformations management in organizations of the real sector of the economy, economic regional systems formation, the territories competitiveness management and innovative development's strategies construction. © 2017, Authors
Development and concentration efficiency study of enterprises innovation activity in real sector of economy
The relevance of the issue under investigation is reasoned by the fact that in growing global competition and expansion context, on the one hand, and economic constraints related to geopolitical tensions, on the other hand, a key factor in the enterprises competitiveness and priority positions achievement in the world market will be their transition to innovative production technologies and business. Topical and promising one in this case is to achieve competitive excellence, increase business efficiency through the innovations' projecting and commercialization. The paper purpose is to investigate the efficiency and specificity level of the ongoing innovation processes in the real sector of the economy as innovative transformations key segment and the basis for increasing the territory competitiveness. The leading method to the problem study is the method of systemic economic analysis, which allows revealing the essence, regularities, trends of the processes occurring at all levels of innovative transformations. To assess the innovative activity concentration and enterprises' innovative development nature, it is proposed to use analysis methods based on the cost efficiency evaluation, depending on the effect magnitude achieved as a result of innovations practical use, enabling to diagnose competitive and non-competitive producing groups, to determine the resource and innovation potential with strategy development further construction. The research materials can be used in innovative transformations management in organizations of the real sector of the economy, economic regional systems formation, the territories competitiveness management and innovative development's strategies construction. © 2017, Authors
Laboratory Diagnostics of Ovarian Cancer among the Elderly Based on the Parameters of Immunoglobulins and Phagocytic Activity of Blood
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