Potential of Energy Savings in the Public Housing Stock of Comunitat Valenciana Region by Applying the MedZEB Cost-Optimal Methodology

Improving energy efficiency in buildings has a key role to play in achieving the ambitious goal of EU-wide climate neutrality by 2050, set out in the European Green Deal. This paper describes a cost-optimal analysis of residential buildings of Valencian Community, Spain. Thus, an assessment of the contribution of total primary energy savings per year (MW/h) of the social dwellings managed by EVha, Entitat Valenciana d’Habitatge i Sòl (eng. Valencian entity for dwelling and ground) towards the national contribution is presented in this paper. To assess it, the MedZEB cost-optimal methodology has been applied to optimise the performance of the building’s envelope. This means that Optimal Renovation Strategies through Life-Cycle Analysis have been applied to obtain the Packages of Optimal Solutions of the different reference buildings in a reference climate. First, the renovation scenario with 100% of the building stock being renovated has been calculated. Then, the renovation scenario of 1%, being the current European rate of renovation and, finally the renovation scenario of 2%, given that the objective of the Renovation Wave is to at least double the annual energy renovation rate of residential and non-residential buildings by 2030 and to foster deep energy renovations.Unión Europea. Horizonte 2020 78507

Evaluación de recursos hídricos y balance hidrogeológico en acuíferos kársticos de montaña. Caso de la Sierra de Grazalema (Cádiz, España)

En este trabajo se presenta el procedimiento para evaluar los recursos hídricos y realizar el balance hidrogeológico de los acuíferos kársticos de la Sierra de Grazalema (provincia de Cádiz, España), durante el periodo 2012/13-2014/15. Por una parte se han cuantificado las salidas de los acuíferos a partir de la integración del hidrograma de los manantiales y por otra se han estimado las entradas, mediante diversas ecuaciones de balance hídrico del suelo: Thornthwaite, Blaney-Criddle y Hargreaves. Los valores medios anuales de recursos determinados con la ecuación de Hargreaves son los que más se asemejan a las salidas medidas en la mayoría de los acuíferos. Sin embargo, en uno de ellos se ha detectado un exceso medio anual de 31 hm3/año de las entradas con respecto a las salidas, que podría estar ligado a transferencias subterráneas a otros sistemas kársticos circundantesUniversidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

Neurosurgical Spasticity Treatment: From Lesion to Neuromodulation Procedures

Spasticity is one of the most important and residual signs after pyramidal and para-pyramidal catastrophic lesions after diverse neurological insults, including stroke, brain and spine trauma and post-radiation; infection and immunological diseases affecting nervous system, between others. Spasticity is normally a compensatory motor mechanism that could ameliorate the patients´ disability. Nevertheless, disastrous spasticity is described when the extremities force is diminished in the affected limbs, or when is impossible to wake o to take objects, maximum when hand or foot deformity is exposed. The objective of this chapter is centered in the neurosurgical treatment of spasticity, including brain lesions with specific targets and the spine with its different modalities. This review shows not only the basic aspects in these techniques, but also the option of infusion pumps and deep brain stimulation. To close, a proposal is stablished to determinate the possible path to treat the spasticity in the future

Limitations and Challenges in the Stability of Cysteamine Eye Drop Compounded Formulations

Accumulation of cystine crystals in the cornea of patients suffering from cystinosis is considered pathognomonic and can lead to severe ocular complications. Cysteamine eye drop compounded formulations, commonly prepared by hospital pharmacy services, are meant to diminish the build-up of corneal cystine crystals. The objective of this work was to analyze whether the shelf life proposed for six formulations prepared following different protocols used in hospital pharmacies is adequate to guarantee the quality and efficacy of cysteamine eye drops. The long-term and in-use stabilities of these preparations were studied using different parameters: content of cysteamine and its main degradation product cystamine; appearance, color and odor; pH and viscosity; and microbiological analysis. The results obtained show that degradation of cysteamine was between 20% and 50% after one month of storage in the long-term stability study and between 35% and 60% in the in-use study. These data confirm that cysteamine is a very unstable molecule in aqueous solution, the presence of oxygen being the main degradation factor. Saturation with nitrogen gas of the solutions offers a means of reducing cysteamine degradation. Overall, all the formulae studied presented high instability at the end of their shelf life, suggesting that their clinical efficacy might be dramatically compromised

Motor Recovery in Different Types of Brachial Plexus Injury Surgeries

Brachial plexus injuries (BPI) affect mostly the young population. The management of these injuries is complex and there are many surgical options for treatment. To evaluate the patient motor component, the British Medical Research Council motor grading scale (BMRC), range-of-motion (ROM), disability of the arm, shoulder, and hand questionnaire (DASH), and push and pull dynamometer are the main clinical assessment tools that provide information about the clinical status regarding motor function. The purpose of this chapter is to show the motor recovery on interventions that are available as surgical alternatives for the management of BPI, through a systematic review of the literature

Innovación en las enseñanzas universitarias: experiencias presentadas en las III Jornadas de Innovación Educativa de la ULL

En este libro se recoge un conjunto de experiencias de innovación educativa desarrolladas en la ULL en el curso 2011-12. Se abordan distintos ámbitos y ramas del conocimiento, y ocupan temáticas variadas que han sido desarrolladas con rigor, y con un claro potencial para su extrapolación a efectos de la mejora educativa en el ámbito universitario. Esta publicación constituye una primera edición de una serie que irá recogiendo las experiencias de innovación educativa de la ULL. Este es un paso relevante para su impulso en nuestra institución, como lo es el de su vinculación con la investigación educativa, para potenciar su publicación en las revistas científicas en este ámbito cada vez más pujante y relevante para las universidades. Sobre todo representan el deseo y el compromiso del profesorado de la ULL para la mejora del proceso educativo mediante la investigación, la evaluación y la reflexión compartida de nuestras prácticas y planteamientos docentes

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements