699 research outputs found
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Food and cash: understanding the role of the retail sector in rural food security in South Africa
A cross validation of Consumer-Based Brand Equity (CBBE) with Private Labels in Spain
Molinillo,S., Ekinci, Y., Japutra, A. (2014)'A cross validation of Consumer-Based Brand Equity (CBBE) with Private Labels in Spain'. in MartĂnez-LĂłpez, GĂĄzquez-Abad, J.C. and Sethuraman, R. J.A. (eds.) Advances in National Brand and Private Label Marketing. Second International Conference, 2015. Springer Proceedings in Business and Economics, pp. 113-125In recent years a number of Consumer-Based Brand Equity (CBBE) models and measurement scales have been introduced in the branding literature. However, examinations of brand equity in Private Labels (PL) are rather limited. This study aims to compare the validity of the two prominent CBBE models those introduced by Yoo and Donthu (2001) and Nam et al. (2011). In order to test the models and make this comparison, the study collected data from 236 respondents who rated private labels in Spain. A list of 30 different fashion and sportswear PL was introduced to respondents. These brands do not make any reference to the retail store in which they are sold. Research findings suggest that the extended CBBE model introduced by Nam et al. (2011) and Ciftci et al. (2014) is more reliable and valid than Yoo and Donthuâs model for assessing PL. Theoretical contributions and managerial implications are discussed.Universidad de MĂĄlaga. Campus de Excelencia Internacional AndalucĂa Tech
Impact of 90Y PET gradient-based tumor segmentation on voxel-level dosimetry in liver radioembolization
Abstract
Background
The purpose was to validate 90Y PET gradient-based tumor segmentation in phantoms and to evaluate the impact of the segmentation method on reported tumor absorbed dose (AD) and biological effective dose (BED) in 90Y microsphere radioembolization (RE) patients. A semi-automated gradient-based method was applied to phantoms and patient tumors on the 90Y PET with the initial bounding volume for gradient detection determined from a registered diagnostic CT or MR; this PET-based segmentation (PS) was compared with radiologist-defined morphologic segmentation (MS) on CT or MRI. AD and BED volume histogram metrics (D90, D70, mean) were calculated using both segmentations and concordance/correlations were investigated. Spatial concordance was assessed using Dice similarity coefficient (DSC) and mean distance to agreement (MDA). PS was repeated to assess intra-observer variability.
Results
In phantoms, PS demonstrated high accuracy in lesion volumes (within 15%), AD metrics (within 11%), high spatial concordance relative to morphologic segmentation (DSCâ>â0.86 and MDAââ0.99, MDAâ<â0.2 mm, AD/BED metrics within 2%). For patients (58 lesions), spatial concordance between PS and MS was degraded compared to in-phantom (average DSC = 0.54, average MDA = 4.8 mm); the average mean tumor AD was 226âÂąâ153 and 197âÂąâ138 Gy, respectively for PS and MS. For patient AD metrics, the best Pearson correlation (r) and concordance correlation coefficient (ccc) between segmentation methods was found for mean AD (râ=â0.94, cccâ=â0.92), but worsened as the metric approached the minimum dose (for D90, râ=â0.77, cccâ=â0.69); BED metrics exhibited a similar trend. Patient PS showed low intra-observer variability (average DSC = 0.81, average MDA = 2.2 mm, average AD/BED metrics within 3.0%).
Conclusions
90Y PET gradient-based segmentation led to accurate/robust results in phantoms, and showed high concordance with MS for reporting mean tumor AD/BED in patients. However, tumor coverage metrics such as D90 exhibited worse concordance between segmentation methods, highlighting the need to standardize segmentation methods when reporting AD/BED metrics from post-therapy 90Y PET. Estimated differences in reported AD/BED metrics due to segmentation method will be useful for interpreting RE dosimetry results in the literature including tumor response data.https://deepblue.lib.umich.edu/bitstream/2027.42/146544/1/40658_2018_Article_230.pd
Magnetic Tower Outflows from a Radial Wire Array Z-pinch
We present the first results of high energy density laboratory astrophysics
experiments which explore the evolution of collimated outflows and jets driven
by a toroidal magnetic field. The experiments are scalable to astrophysical
flows in that critical dimensionless numbers such as the Mach number, the
plasma beta and the magnetic Reynolds number are all in the astrophysically
appropriate ranges. Our experiments use the MAGPIE pulsed power machine and
allow us to explore the role of magnetic pressure in creating and collimating
the outflow as well as showing the creation of a central jet within the broader
outflow cavity. We show that currents flow along this jet and we observe its
collimation to be enhanced by the additional hoop stresses associated with the
generated toroidal field. Although at later times the jet column is observed to
go unstable, the jet retains its collimation. We also present simulations of
the magnetic jet evolution using our two-dimensional resistive
magneto-hydrodynamic (MHD) laboratory code. We conclude with a discussion of
the astrophysical relevance of the experiments and of the stability properties
of the jet.Comment: Accepted by MNRAS. 17 pages without figures. Full version with
figures can be found at
http://www.pas.rochester.edu/~afrank/labastro/MF230rv.pd
Prognostic impact of genetic characterization in the GIMEMA LAM99P multicenter study for newly diagnosed acute myeloid leukemia
Recent advances in genetic characterization of acute myeloid leukemia indicate that combined cytogenetic and molecular analyses provide better definition of prognostic groups. The aim of this study was to verify this prospectively in a large group of patients
NEMO: A Project for a km Underwater Detector for Astrophysical Neutrinos in the Mediterranean Sea
The status of the project is described: the activity on long term
characterization of water optical and oceanographic parameters at the Capo
Passero site candidate for the Mediterranean km neutrino telescope; the
feasibility study; the physics performances and underwater technology for the
km; the activity on NEMO Phase 1, a technological demonstrator that has
been deployed at 2000 m depth 25 km offshore Catania; the realization of an
underwater infrastructure at 3500 m depth at the candidate site (NEMO Phase 2).Comment: Proceeding of ISCRA 2006, Erice 20-27 June 200
The ANTARES Optical Beacon System
ANTARES is a neutrino telescope being deployed in the Mediterranean Sea. It
consists of a three dimensional array of photomultiplier tubes that can detect
the Cherenkov light induced by charged particles produced in the interactions
of neutrinos with the surrounding medium. High angular resolution can be
achieved, in particular when a muon is produced, provided that the Cherenkov
photons are detected with sufficient timing precision. Considerations of the
intrinsic time uncertainties stemming from the transit time spread in the
photomultiplier tubes and the mechanism of transmission of light in sea water
lead to the conclusion that a relative time accuracy of the order of 0.5 ns is
desirable. Accordingly, different time calibration systems have been developed
for the ANTARES telescope. In this article, a system based on Optical Beacons,
a set of external and well-controlled pulsed light sources located throughout
the detector, is described. This calibration system takes into account the
optical properties of sea water, which is used as the detection volume of the
ANTARES telescope. The design, tests, construction and first results of the two
types of beacons, LED and laser-based, are presented.Comment: 21 pages, 18 figures, submitted to Nucl. Instr. and Meth. Phys. Res.
Peripheral blasts are associated with responses to ruxolitinib and outcomes in patients with chronic-phase myelofibrosis
Standalone vertex ďŹnding in the ATLAS muon spectrometer
A dedicated reconstruction algorithm to find decay vertices in the ATLAS muon spectrometer is presented. The algorithm searches the region just upstream of or inside the muon spectrometer volume for multi-particle vertices that originate from the decay of particles with long decay paths. The performance of the algorithm is evaluated using both a sample of simulated Higgs boson events, in which the Higgs boson decays to long-lived neutral particles that in turn decay to bbar b final states, and pp collision data at âs = 7 TeV collected with the ATLAS detector at the LHC during 2011
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