Direct and indirect costs of paediatric asthma in the UK : a cost analysis

We thank all the children who took part in the study and their families, and the staff at recruitment sites who facilitated identification, recruitment and follow-up of study participants. We acknowledge Jessica Wood, Victoria Bell and Andrea Fraser from the RAACENO trial office. We also thank Aileen Neilson who initially led the health economic aspects of the RAACENO trial.Peer reviewe

Just transitions and sociotechnical innovation in the social housing sector: an assemblage analysis of residents’ perspectives

Creating low-carbon pathways for domestic electricity and heating is a core aspect of the UK Government's housing strategy. Understanding issues of energy justice and the socio-technical dynamics of low-carbon innovation are vital for successfully implementing new technologies and retrofit measures across diverse communities and different housing types. The social housing sector is particularly important in the study of just domestic low-carbon transitions due to the challenges faced by residents concerning energy affordability and insecurity during the ongoing cost of living crisis in the UK. This qualitative study, conducted in the Northeast of England, adopts an assemblage thinking approach to examine the experiences of social housing residents. Through thematic analysis of interviewee responses, we identify themes related to cost and affordability; decision-making dynamics and energy justice; disruption, retrofit and ‘fabric first’; energy autonomy and the practicalities of technology choice; and environmental values and collective climate action. We find that justice in the low-carbon home requires social housing organisations to strengthen mechanisms for resident engagement and interconnectedness before retrofit roll-out, to identify independent sources and arbiters of information on upfront and long-term energy costs, to ensure effective mechanisms for the social control of energy use, and to provide a platform to encourage nascent energy citizenship through which residents link pro-environmental behaviours in the home to broader networks of social action on climate change

Education for sustainable development: Guidance for UK higher education providers

This guidance has been prepared by representatives of the higher education community with expertise in education and sustainable development. It has been produced via collaboration between the Quality Assurance Agency for Higher Education (QAA) and the Higher Education Academy (HEA). The guidance is intended to be of practical help to higher education providers working with students to foster their knowledge, understanding and skills in the area of sustainable development. The guidance recognises that there are many ways in which this may be achieved and is not prescriptive about delivery. Instead it offers an outcomes-based framework for use in curriculum design, and general guidance on approaches to teaching, learning and assessment. The guidance is intended to be relevant to educators in all disciplines wishing to embed or include learning about sustainable development within their curricula. This guidance is intended to complement Chapter B3 of the UK Quality Code for Higher Education (Quality Code) dedicated to learning and teaching, but it does not form an explicit part of it. The Quality Code sets out the expectations that all providers of UK higher education are required to meet and is used in QAA review processes. The guidance is intended to apply to all parts of the UK

The design and development of an experience measure for a peer community moderated forum in a digital mental health service.

Online digital mental health communities can contribute to users' mental health positively and negatively. Yet the measurement of experience, outcomes and impact mechanisms relating to digital mental health communities is difficult to capture. In this paper we demonstrate the development of an online experience measure for a specific children and young people's community forum inside a digital mental health service. The development of the Peer Online Community Experience Measure (POCEM) is informed by a multi-phased design: (i) item reduction through Estimate-Talk-Estimate modified Delphi methods, (ii) user testing with think-aloud protocols and (iii) a pilot study within the digital service community to explore observational data within the platform. Experts in the field were consulted to help reduce the items in the pool and to check their theoretical coherence. User testing workshops helped to inform the usability appearance, wording, and purpose of the measure. Finally, the pilot results highlight completion rates, differences in scores for age and roles and "relate to others", as the most frequent domain mechanism of support for this community. Outcomes frequently selected show the importance of certain aspects of the community, such as safety, connection, and non-judgment previously highlighted in the literature. Experience measures like this one could be used as indicators of active therapeutic engagement within the forum community and its content but further research is required to ascertain its acceptability and validity. Multi-phased approaches involving stakeholders and user-centred design activities enhances the development of digitally enabled measurement tools

Treatment guided by fractional exhaled nitric oxide in addition to standard care in 6- to 15-year-olds with asthma : the RAACENO RCT

Funding This project was funded by the Efficacy and Mechanism Evaluation (EME) programme, a MRC and National Institute for Health and Care Research (NIHR) partnership. This will be published in full in Efficacy and Mechanism Evaluation; Vol. 9, No. 4. See the NIHR Journals Library website for further project information.Peer reviewedPublisher PD

Triumph and tribulation for shallow water fauna during the Paleocene–Eocene transition; insights from the United Arab Emirates

This is the final version. Available on open access from Borntraeger Science Publishers via the DOI in this recordThe Paleocene–Eocene transition was a time of short-term rapid climatic and biotic change, superimposed on a long-term warming trend. The response of shallow tropical carbonate systems to past rapid warming is important to understand in the context of ongoing and future anthropogenic global warming. Larger benthic foraminifera (LBF) were abundant and important components of shallow water ecosystems throughout the early Paleogene and are sensitive to environmental change, making them ideal organisms to track shallow marine biodiversity. Furthermore, through the use of integrated bio- and chemostratigraphy it is possible to correlate the shallow (<100 m) and deep water realms to create a regional stratigraphic framework for the time period. Here we present a new LBF biostratigraphic and high-resolution carbonate carbon isotopic record spanning the Paleocene– Eocene transition from the onshore sub-surface of the United Arab Emirates (UAE). Results show a turnover event in the LBF assemblage during the early Eocene, wherein there are a number of first and last occurrences of species. However, assemblages remain generally stable coincident with the large negative carbon isotope excursion interpreted to be the onset of the Paleocene–Eocene thermal maximum (PETM). Turnover in the LBF assemblage in the early Eocene likely occurred due to the crossing of a long-term climatic and oceanographic threshold. The impacts of this long-term climatic change on the overall biotic assemblage at this site are significant, with LBF outcompeting a previously diverse community of corals, gastropods, and bivalves to become the dominant carbonate producers through the Paleocene–Eocene transition. Despite this, modern studies suggest that LBF are not immune to impacts of anthropogenic climate change, perhaps due to the significantly higher rates of change in the modern compared to the Paleocene–Eocene transition.Natural Environment Research Council (NERC)European Research Council (ERC

Training future generations to deliver evidence-based conservation and ecosystem management

1. To be effective, the next generation of conservation practitioners and managers need to be critical thinkers with a deep understanding of how to make evidence-based decisions and of the value of evidence synthesis. 2. If, as educators, we do not make these priorities a core part of what we teach, we are failing to prepare our students to make an effective contribution to conservation practice. 3. To help overcome this problem we have created open access online teaching materials in multiple languages that are stored in Applied Ecology Resources. So far, 117 educators from 23 countries have acknowledged the importance of this and are already teaching or about to teach skills in appraising or using evidence in conservation decision-making. This includes 145 undergraduate, postgraduate or professional development courses. 4. We call for wider teaching of the tools and skills that facilitate evidence-based conservation and also suggest that providing online teaching materials in multiple languages could be beneficial for improving global understanding of other subject areas.Peer reviewe