Computer vision application proposal for smart inventory systems in convenience store reach-in refrigerators

Inventory systems in reach-in refrigerators employ manual or smart inventory outdated methods, although efficient, new methods like computer vision could render better results in less time, with less human intervention. The objective of this work proposes a computer vision system to acquire an inventory of products placed in reach-in convenience store refrigerators. A comparative of different computer vision object recognition models was performed to select the most appropriate model for the application. Then, based on the model characteristics and the application requirements, a YOLOv4 object recognition model was selected. Along with a 2-dimension camera positioning rig to capture a live video feed of the products to count for the inventory. Future works could include a real size prototype and further development into a commercial product.ITESO, A. C

Alimentación práctica del cerdo

The feed represent over 65% of production costs, so should be established as a priority. It is not enough that a diet meets the nutritional needs of pigs, the ration formulation must right with official regulations governing each country for the use and manufacture of feed. Also, the feed should be easy to preserve and supplying, taking into the wide variety to installations (feeders and drinkers) used in various stages of pigs. However, the fundamental objective of the formulation of a diet is that it contains the necessary nutrients in the correct proportions and balance, considering the physiological stage, weight, age, sex, genetic potential, health status, season and production objectives with a the legal constraints. Once accomplished the formulation, the next step will be insure preparing the feed under conditions that ensure the safety, traceability and lower cost of the same. To this challenge, is adding the need to the right with environmental regulations related to feed and animal welfare.La alimentación representan alrededor del 65% de los costes de producción, por ello debe establecerse como una prioridad. No es suficiente que una dieta cumpla con las necesidades nutricionales de los cerdos, la formulación debe obedecer las normativas oficiales que rigen en cada país para el uso y fabricación de alimentos. Asimismo, el alimento debe ser fácil de conservar y suministrar, asumiendo la gran variedad de instalaciones (comederos y bebederos) utilizadas en las distintas etapas de los cerdos. Sin embargo, el objetivo fundamental de la formulación de una dieta es que contenga los nutrientes necesarios en las cantidades correctas y equilibradas, considerando la etapa fisiológica, peso, edad, sexo, potencial genético, estado de salud, época del año, objetivos productivos y de producto final, así como las limitantes legales. Una vez cumplida la formulación, el siguiente paso es asegurar que ésta sea elaborada bajo condiciones que garanticen la inocuidad, trazabilidad y bajo costo de la misma. A este desafío, se añade la necesidad de cumplir con las normativas ambientales relacionadas con la alimentación y bienestar animal

Development of lntraepithelial Cells in the Porcine Small Intestine

The number, phenotype, localisation and development of intraepithelial lymphocytes (IEL) from duodenum (Du) and ileum (Il) were studied by immunohistochemistry (IHC) and light and electron microscopy in unweaned (0–7 weeks old) and six months-old pigs. Developmental changes at birth showed that 38% of the total lymphocytes in the villi were IEL, mainly of the CD2+CD4-CD8- double negative (DN) phenotype. That proportion rose to over 50% at week 5 after birth, resembling adult proportion, although still with fewer cells than in adult pigs. CD4+ cells appeared relatively early in life although they were confined to the lamina propria (LP) and CD8+ cells were found only in low numbers. In the villi of adult animals, almost half of the total number of lymphocytes were IEL (49% Du, 52% Il). Over half of these IEL (52% Du, 53% Il) showed the CD2+CD4-CD8+ phenotype and were localized at the epithelium's basement membrane. Numerous (43% Du, 42% Il) DN IEL were found grouped at the enterocyte nucleus level and relatively few (5% in Du and Il) granular IEL were found apically in the epithelium. These proportions were homogeneously maintained along the villi's tip, middle and bottom, suggesting that the IEL may have their origin in the LP. Therefore, the IEL compartment in the porcine intestine develops slowly with age and is actually composed by a heterogeneous population of cells (null, DN and CD8+). These results may explain the increased susceptibility of young animals to disease during the lactation period and should be taken into account when functional studies are carried out with IEL. The quantitative results of this paper established a model for studies on the effect of age, diet, normal flora, infection and oral immunization on the IEL of the gut

Migration, Agribusiness and Nutritional Status of Children under Five in Northwest Mexico

The aim of this study was to examine the nutritional status of children of Mexican migrant worker families under five years of age within the context of global food markets. The sample included 404 children less than five years old from farms and agricultural communities in northwest Mexico. Prevalence of stunting and underweight of children appeared very similar to that of indigenous children from the national sample survey (difference 0.9 and 1.6 percentage points, respectively). Compared to the national sample of Mexican children, stunting and underweight seemed higher in migrant children (difference 17.7 and 4.5 percentage points, respectively), but wasting, an indicator of both chronic and acute undernutrition, appeared to indicate a process of nutritional recuperation. Migrant children living in poverty and suffering from chronic undernutrition, poor performance and scarce education opportunities, can be expected to eventually become agricultural workers with low productivity and poor general health. Consumer’s demands on social and environmental standards of fresh food production in developed countries could be an opportunity to impact the lives of migrant agricultural workers, their families and communities

Do ResearchGate Scores create ghost academic reputations?

[EN] The academic social network site ResearchGate (RG) has its own indicator, RG Score, for its members. The high profile nature of the site means that the RG Score may be used for recruitment, promotion and other tasks for which researchers are evaluated. In response, this study investigates whether it is reasonable to employ the RG Score as evidence of scholarly reputation. For this, three different author samples were investigated. An outlier sample includes 104 authors with high values. A Nobel sample comprises 73 Nobel winners from Medicine and Physiology, Chemistry, Physics and Economics (from 1975 to 2015). A longitudinal sample includes weekly data on 4 authors with different RG Scores. The results suggest that high RG Scores are built primarily from activity related to asking and answering questions in the site. In particular, it seems impossible to get a high RG Score solely through publications. Within RG it is possible to distinguish between (passive) academics that interact little in the site and active platform users, who can get high RG Scores through engaging with others inside the site (questions, answers, social networks with influential researchers). Thus, RG Scores should not be mistaken for academic reputation indicators.Alberto Martin-Martin enjoys a four-year doctoral fellowship (FPU2013/05863) granted by the Ministerio de Educacion, Cultura, y Deporte (Spain). Enrique Orduna-Malea holds a postdoctoral fellowship (PAID-10-14), from the Polytechnic University of Valencia (Spain).Orduña Malea, E.; Martín-Martín, A.; Thelwall, M.; Delgado-López-Cózar, E. (2017). Do ResearchGate Scores create ghost academic reputations?. Scientometrics. 112(1):443-460. https://doi.org/10.1007/s11192-017-2396-9S4434601121Bosman, J. & Kramer, B. (2016). Innovations in scholarly communication—data of the global 2015–2016 survey. Available at: http://zenodo.org/record/49583 #. Accessed December 11, 2016.González-Díaz, C., Iglesias-García, M., & Codina, L. (2015). Presencia de las universidades españolas en las redes sociales digitales científicas: Caso de los estudios de comunicación. El profesional de la información, 24(5), 1699–2407.Goodwin, S., Jeng, W., & He, D. (2014). Changing communication on ResearchGate through interface updates. Proceedings of the American Society for Information Science and Technology, 51(1), 1–4.Hicks, D., Wouters, P., Waltman, L., de Rijcke, S., & Rafols, I. (2015). The Leiden Manifesto for research metrics. Nature, 520(7548), 429–431.Hoffmann, C. P., Lutz, C., & Meckel, M. (2015). A relational altmetric? Network centrality on ResearchGate as an indicator of scientific impact. Journal of the Association for Information Science and Technology, 67(4), 765–775.Jiménez-Contreras, E., de Moya Anegón, F., & Delgado López-Cózar, E. (2003). The evolution of research activity in Spain: The impact of the National Commission for the Evaluation of Research Activity (CNEAI). Research Policy, 32(1), 123–142.Jordan, K. (2014a). Academics’ awareness, perceptions and uses of social networking sites: Analysis of a social networking sites survey dataset (December 3, 2014). Available at: http://dx.doi.org/10.2139/ssrn.2507318 . Accessed December 11, 2016.Jordan, K. (2014b). Academics and their online networks: Exploring the role of academic social networking sites. First Monday, 19(11). Available at: http://dx.doi.org/10.5210/fm.v19i11.4937 . Accessed December 11, 2016.Jordan, K. (2015). Exploring the ResearchGate score as an academic metric: reflections and implications for practice. Quantifying and Analysing Scholarly Communication on the Web (ASCW’15), 30 June 2015, Oxford. Available at: http://ascw.know-center.tugraz.at/wp-content/uploads/2015/06/ASCW15_jordan_response_kraker-lex.pdf . Accessed December 11, 2016.Kadriu, A. (2013). Discovering value in academic social networks: A case study in ResearchGate. Proceedings of the ITI 2013—35th Int. Conf. on Information Technology Interfaces Information Technology Interfaces, pp. 57–62.Kraker, P. & Lex, E. (2015). A critical look at the ResearchGate score as a measure of scientific reputation. Proceedings of the Quantifying and Analysing Scholarly Communication on the Web workshop (ASCW’15), Web Science conference 2015. Available at: http://ascw.know-center.tugraz.at/wp-content/uploads/2016/02/ASCW15_kraker-lex-a-critical-look-at-the-researchgate-score_v1-1.pdf . Accessed December 11, 2016.Li, L., He, D., Jeng, W., Goodwin, S. & Zhang, C. (2015). Answer quality characteristics and prediction on an academic Q&A Site: A case study on ResearchGate. Proceedings of the 24th International Conference on World Wide Web Companion, pp. 1453–1458.Martín-Martín, A., Orduna-Malea, E., Ayllón, J. M. & Delgado López-Cózar, E. (2016). The counting house: measuring those who count. Presence of Bibliometrics, Scientometrics, Informetrics, Webometrics and Altmetrics in the Google Scholar Citations, ResearcherID, ResearchGate, Mendeley & Twitter. Available at: https://arxiv.org/abs/1602.02412 . Accessed December 11, 2016.Martín-Martín, A., Orduna-Malea, E. & Delgado López-Cózar, E. (2016). The role of ego in academic profile services: Comparing Google Scholar, ResearchGate, Mendeley, and ResearcherID. Researchgate, Mendeley, and Researcherid. The LSE Impact of Social Sciences blog. Available at: http://blogs.lse.ac.uk/impactofsocialsciences/2016/03/04/academic-profile-services-many-mirrors-and-faces-for-a-single-ego . Accessed December 11, 2016.Matthews, D. (2016). Do academic social networks share academics’ interests?. Times Higher Education. Available at: https://www.timeshighereducation.com/features/do-academic-social-networks-share-academics-interests . Accessed December 11, 2016.Memon, A. R. (2016). ResearchGate is no longer reliable: leniency towards ghost journals may decrease its impact on the scientific community. Journal of the Pakistan Medical Association, 66(12), 1643–1647.Mikki, S., Zygmuntowska, M., Gjesdal, Ø. L. & Al Ruwehy, H. A. (2015). Digital presence of norwegian scholars on academic network sites-where and who are they?. Plos One 10(11). Available at: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0142709 . Accessed December 11, 2016.Nicholas, D., Clark, D., & Herman, E. (2016). ResearchGate: Reputation uncovered. Learned Publishing, 29(3), 173–182.Orduna-Malea, E., Martín-Martín, A., & Delgado López-Cózar, E. (2016). The next bibliometrics: ALMetrics (Author Level Metrics) and the multiple faces of author impact. El profesional de la información, 25(3), 485–496.Ortega, Jose L. (2015). Relationship between altmetric and bibliometric indicators across academic social sites: The case of CSIC’s members. Journal of informetrics, 9(1), 39–49.Ortega, Jose L. (2016). Social network sites for scientists. Cambridge: Chandos.Ovadia, S. (2014). ResearchGate and Academia. edu: Academic social networks. Behavioral & Social Sciences Librarian, 33(3), 165–169.Thelwall, M., & Kousha, K. (2015). ResearchGate: Disseminating, communicating, and measuring Scholarship? Journal of the Association for Information Science and Technology, 66(5), 876–889.Thelwall, M. & Kousha, K. (2017). ResearchGate articles: Age, discipline, audience size and impact. Journal of the Association for Information Science and Technology, 68(2), 468–479.Van Noorden, R. (2014). Online collaboration: Scientists and the social network. Nature, 512(7513), 126–129.Wilsdon, J., Allen, L., Belfiore, E., Campbell, P., Curry, S., Hill, S. et al. (2015). The Metric Tide: Independent Review of the Role of Metrics in Research Assessment and Management. HEFCE. Available at: http://doi.org/10.13140/RG.2.1.4929.1363 . Accessed December 11, 2016

A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability

43 p.-5 fig.Despite the approval of several multikinase inhibitors that target SRC and the overwhelming evidence of the role of SRC in the progression and resistance mechanisms of many solid malignancies, inhibition of its kinase activity has thus far failed to improve patient outcomes. Here we report the small molecule eCF506 locks SRC in its native inactive conformation, thereby inhibiting both enzymatic and scaffolding functions that prevent phosphorylation and complex formation with its partner FAK. This unprecedented mechanism of action resulted in highly potent and selective pathway inhibition, in culture and in vivo. Treatment with eCF506 resulted in increased antitumor efficacy and tolerability in syngeneic murine cancer models, demonstrating significant therapeutic advantages over existing SRC/ABL inhibitors. Therefore, this novel mode of inhibiting SRC could lead to improved treatment of SRC-associated disorders.C.T. thanks the CMVM of the University of Edinburgh (Principal's scholarship). D.L. acknowledges support from the Spanish Ministry of Science, Innovation and Universities for the Spanish State Research Agency Retos Grant RTI2018-099318-B-I00, cofunded by the European Regional Development Fund (FEDER). E.R.W., J.C.D. and K.G.M. are funded by CRUK. J.R.L.O. acknowledges support from the Molecular Interactions Facility funds at the CIB-CSIC. T.V. is funded by H2020-MSCA-IF-2016-749299. RCM thanks the support from the Vice Rectorate for Research of the University of Granada. X.-F.L. and B.-Z.Q. are funded by a CRUK Career Development Fellowship (C49791/A17367). B.-Z.Q. also acknowledges support from an ERC Starting Grant (716379). C.S, M.C.F. and V.G.B are funded by CRUK Programme Grant C157/A15703. N.O.C. and A.U.B are grateful to the CMVM of the University of Edinburgh and Wellcome Trust for financial support (ISSF3).Peer reviewe

Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE

MAGIC Upper Limits for two Milagro-detected, Bright Fermi Sources in the Region of SNR G65.1+0.6

We report on the observation of the region around supernova remnant G65.1+0.6 with the stand-alone MAGIC-I telescope. This region hosts the two bright GeV gamma-ray sources 1FGL J1954.3+2836 and 1FGL J1958.6+2845. They are identified as GeV pulsars and both have a possible counterpart detected at about 35 TeV by the Milagro observatory. MAGIC collected 25.5 hours of good quality data, and found no significant emission in the range around 1 TeV. We therefore report differential flux upper limits, assuming the emission to be point-like (<0.1 deg) or within a radius of 0.3 deg. In the point-like scenario, the flux limits around 1 TeV are at the level of 3 % and 2 % of the Crab Nebula flux, for the two sources respectively. This implies that the Milagro emission is either extended over a much larger area than our point spread function, or it must be peaked at energies beyond 1 TeV, resulting in a photon index harder than 2.2 in the TeV band.Comment: 8 pages, 3 figures, 1 tabl

Combined search for the quarks of a sequential fourth generation

Results are presented from a search for a fourth generation of quarks produced singly or in pairs in a data set corresponding to an integrated luminosity of 5 inverse femtobarns recorded by the CMS experiment at the LHC in 2011. A novel strategy has been developed for a combined search for quarks of the up and down type in decay channels with at least one isolated muon or electron. Limits on the mass of the fourth-generation quarks and the relevant Cabibbo-Kobayashi-Maskawa matrix elements are derived in the context of a simple extension of the standard model with a sequential fourth generation of fermions. The existence of mass-degenerate fourth-generation quarks with masses below 685 GeV is excluded at 95% confidence level for minimal off-diagonal mixing between the third- and the fourth-generation quarks. With a mass difference of 25 GeV between the quark masses, the obtained limit on the masses of the fourth-generation quarks shifts by about +/- 20 GeV. These results significantly reduce the allowed parameter space for a fourth generation of fermions.Comment: Replaced with published version. Added journal reference and DO

Measurement of the t t-bar production cross section in the dilepton channel in pp collisions at sqrt(s) = 7 TeV

The t t-bar production cross section (sigma[t t-bar]) is measured in proton-proton collisions at sqrt(s) = 7 TeV in data collected by the CMS experiment, corresponding to an integrated luminosity of 2.3 inverse femtobarns. The measurement is performed in events with two leptons (electrons or muons) in the final state, at least two jets identified as jets originating from b quarks, and the presence of an imbalance in transverse momentum. The measured value of sigma[t t-bar] for a top-quark mass of 172.5 GeV is 161.9 +/- 2.5 (stat.) +5.1/-5.0 (syst.) +/- 3.6(lumi.) pb, consistent with the prediction of the standard model.Comment: Replaced with published version. Included journal reference and DO