Physical Science Day: Design, Implementation, and Assessment

Physical Science Day at The University of Texas–Pan American (UTPA), in collaboration with the Edinburg Consolidated Independent School District, has been designed, developed and implemented to address an identified fundamental shortcoming in our educational process within this primarily (90+%) Hispanic serving border region. Physical Science Day overcomes the lack of knowledge about what physics is by raising youth awareness of physics as the foundation of science, engineering and technology disciplines, through activities including hands-on laboratory experiments, career orientation, and higher educational student and graduated student testimonials. Thus, Physical Science Day encourages, attracts, and enables more Hispanic youth towards science, technology and engineering disciplines in higher education. Pre- and post-survey results showed that Physical Science Day is effective at increasing student knowledge about physics, physical science, and chemistry programs, raising awareness of broad career opportunities, as well as for stimulating youth interest towards studying such disciplines at UTPA

Instalaciones sanitarias utilizando sistemas de recirculación del agua potable

La norma de instalaciones sanitarias I.S. 010 (2006) no impide la instalación de elementos que puedan ahorrar energía y agua para el caso de agua caliente, solo presenta indicaciones con respecto al uso de los sistemas de agua, desagüe y de las conexiones a utilizar dentro de una edificación, así como las dimensiones y las herramientas adecuadas según el consumo para el cual se diseñará el edificio. Con base en estos datos mencionados, la investigación presentada tiene como núcleo la aplicación de elementos que permitan la recirculación del agua potable en una vivienda, de tal manera que se evite el desperdicio de agua, puesto que, en la actualidad, el mundo pasa por un grave problema con respecto a los recursos hidrológicos. Asimismo, según estudios realizados por la ONU y presentados por la BBC News: “el aumento de la población anual es cada vez mayor en el mundo y asimismo es un indicativo del aumento del consumo de agua y se prevé que para el año 2050 la mitad del mundo estaría pasando por una gran escasez de agua”. En la actualidad, el sistema de agua caliente en las edificaciones genera pérdidas de agua potable debido a que cuando se abre el grifo de agua, debe pasar un tiempo pronunciado para que el agua alcance el nivel de temperatura requerido por el consumidor. En consecuencia, se genera un desperdicio de agua fría, es así que se tiene planeado implementar este sistema, el cual permitirá ahorrar en agua potable y evitar futuras pérdidas, que medidos anualmente conforman una cantidad en metros cúbicos que no es despreciable. Para la aplicación de estos elementos se plantea presentar los beneficios que implicaría su instalación en edificaciones peruanas. Finalmente, se presenta la instalación de este sistema de recirculación de agua potable aplicable en agua caliente para una edificación denominada PROYECTO CUSCO, ubicada en la ciudad de Cusco, distrito de Wánchaq. En la que se presenta la distribución de este nuevo sistema en el proyecto y se cumple con los requisitos impuestos por la norma I.S. 010 (2006) correspondiente a instalaciones sanitarias del reglamento nacional de edificaciones. Como conclusión, se demuestra que es aplicable la utilización de sistemas de recirculación y que benefician no solo al consumidor sino también al planeta, teniendo más opciones de proteger nuestro entorno para las generaciones futuras

Gradual polyploid genome evolution revealed by pan-genomic analysis of Brachypodium hybridum and its diploid progenitors

Our understanding of polyploid genome evolution is constrained because we cannot know the exact founders of a particular polyploid. To differentiate between founder effects and post polyploidization evolution, we use a pan-genomic approach to study the allotetraploid Brachypodium hybridum and its diploid progenitors. Comparative analysis suggests that most B. hybridum whole gene presence/absence variation is part of the standing variation in its diploid progenitors. Analysis of nuclear single nucleotide variants, plastomes and k-mers associated with retrotransposons reveals two independent origins for B. hybridum, ~1.4 and ~0.14 million years ago. Examination of gene expression in the younger B. hybridum lineage reveals no bias in overall subgenome expression. Our results are consistent with a gradual accumulation of genomic changes after polyploidization and a lack of subgenome expression dominance. Significantly, if we did not use a pan-genomic approach, we would grossly overestimate the number of genomic changes attributable to post polyploidization evolution

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Gradual polyploid genome evolution revealed by pan-genomic analysis of Brachypodium hybridum and its diploid progenitors

Our understanding of polyploid genome evolution is constrained because we cannot know the exact founders of a particular polyploid. To differentiate between founder effects and post polyploidization evolution, we use a pan-genomic approach to study the allotetraploid Brachypodium hybridum and its diploid progenitors. Comparative analysis suggests that most B. hybridum whole gene presence/absence variation is part of the standing variation in its diploid progenitors. Analysis of nuclear single nucleotide variants, plastomes and k-mers associated with retrotransposons reveals two independent origins for B. hybridum, ~1.4 and ~0.14 million years ago. Examination of gene expression in the younger B. hybridum lineage reveals no bias in overall subgenome expression. Our results are consistent with a gradual accumulation of genomic changes after polyploidization and a lack of subgenome expression dominance. Significantly, if we did not use a pan-genomic approach, we would grossly overestimate the number of genomic changes attributable to post polyploidization evolution

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

Collection of human and environmental data on pesticide use in Europe and Argentina: Field study protocol for the SPRINT project

Current farm systems rely on the use of Plant Protection Products (PPP) to secure high productivity and control threats to the quality of the crops. However, PPP use may have considerable impacts on human health and the environment. A study protocol is presented aiming to determine the occurrence and levels of PPP residus in plants (crops), animals (livestock), humans and other non-target species (ecosystem representatives) for exposure modelling and impact assessment. To achieve this, we designed a cross-sectional study to compare conventional and organic farm systems across Europe. Environmental and biological samples were/are being/will be collected during the 2021 growing season, at 10 case study sites in Europe covering a range of climate zones and crops. An additional study site in Argentina will inform the impact of PPP use on growing soybean which is an important European protein-source in animal feed. We will study the impact of PPP mixtures using an integrated risk assessment methodology. The fate of PPP in environmental media (soil, water and air) and in the homes of farmers will be monitored. This will be complemented by biomonitoring to estimate PPP uptake by humans and farm animals (cow, goat, sheep and chicken), and by collection of samples from non-target species (earthworms, fish, aquatic and terrestrial macroinvertebrates, bats, and farm cats). We will use data on PPP residues in environmental and biological matrices to estimate exposures by modelling. These exposure estimates together with health and toxicity data will be used to predict the impact of PPP use on environment, plant, animal and human health. The outcome of this study will then be integrated with socio-economic information leading to an overall assessment used to identify transition pathways towards more sustainable plant protection and inform decision makers, practitioners and other stakeholders regarding farming practices and land use policy

Estudio del trabajo en la maquila de Suppla Mondelez con el objetivo de estandarizar los procesos representativos de la operación

En los últimos tiempos la maquila SUPPLA ha estado en un constante crecimiento, adquiriendo cada vez más y más clientes reconocidos, entre estos acaba de adquirir un nuevo cliente llamado Mondelez, cliente que anteriormente fue conocido como Cadbury – Chiclets adamns, la maquiladora SUPPLA al adquirir este cliente e iniciar con la producción de sus ofertas observan la necesidad de estandarizar sus procesos, buscando poder brindarle rentabilidad al negocio y mantener un buen servicio al cliente con el cumplimiento de sus pedidos. Este proyecto se enfocó en el mejoramiento de los tres procesos identificados como Pareto en la organización, buscando la manera de que las mejoras implementadas afecten positivamente por lo menos el 80% de la producción en la maquila. Gracias al estudio sistemático se fueron detectando las falencias en los procesos de producción, y poco a poco generando propuestas que permitieran eliminar los desperdicios detectados, disminuir la cantidad de actividades necesarias para la realización de las ofertas, reducir tiempos de producción y aumentar la capacidad de producción de las líneas de producción. A continuación se presentaran todos los pasos necesarios para lograr una mejora significativa en la organización y alcanzar las metas establecidas en el proyecto. Como resultado se esto se podrá observar cómo se estandarizaron las actividades de producción para cada una de las líneas, la reducción de cuellos de botellas en las líneas de producción, los balanceos de línea indicando los números de personas ideales para realizar las ofertas. Todo esto al final resumido en mejoras porcentuales de producción y ahorros en pesos ($) para la organizaciónPregradoIngeniero(a) Industria