Infestazione intestinale da Schistosoma mansoni: un caso emblematico di importazione

Viene descritto, sia dal punto di vista clinico che parassitologico, un caso di importazione di schistosomiasi intestinale da S. mansoni contratta durante un soggiorno in Tanzania. Dopo circa 50 giorni da un contatto casuale ma ripetuto con le acque del Lago Vittoria, al soggetto, giovane adulto in missione umanitaria, compare febbre elevata, accompagnata da astenia (presente da più giorni) cui segue un episodio di diarrea acuta. La comparsa anche di una ipereosinofilia, dapprima assente, spinge il curante ad eseguire immediatamente un esame coproparassitologico standard (in precedenza sempre negativo) che risulta positivo per uova di S. mansoni. La terapia condotta con praziquantel risolve il caso e porta a guarigione il soggetto, cui inizialmente era stata esclusa la malaria, allorché dopo circa 1 mese dal rientro aveva presentato rialzo termico con disturbi respiratori

Diabetes, sarcopenia and chronic kidney disease; the screening for CKD among older people across Europe (SCOPE) study

ackground:Sarcopenia may be more present in older adults with diabetes (DM). Accordingly, we evaluated the prevalence of sarcopenia and its associated risk factors among community‑dwelling older adults with DM.Methods:A cross‑sectional analysis of older people living in the community was carried out. Participants (aged 75 years and more) came from an European multicenter prospective cohort (SCOPE study). Global geriatric assess‑ment including short physical performance battery, handgrip strength test and bioelectrical impedance analysis was performed. Sarcopenia was defined by the updated criteria of the European Working Group on Sarcopenia in Older People (EWGSOP2). Estimated glomerular filtration rate (eGFR) was calculated using Berlin Initiative Study (BIS) to define the stages of chronic kidney disease (CKD). Previous known DM was defined as physician‑diagnosed DM reg‑istered in the patient's medical record or the use of DM‑related medications. Hemoglobin A1c levels and specific DM therapies administered were collected. Time elapsed from the first diagnosis of DM was not collected and, therefore, was not included in the analyses.Results:A total of 1,420 subjects were evaluated with a median age of 79.0 (6.0) years, of which 804 (56.6%) were women and 615 (43.3%) men; 315 (22.2%) participants had prior DM diagnosis, with a median age of 80.0 (6.0), 146 (46.3%) were women. Using EWGSOP2 definition, 150 (10.6%) participants in the SCOPE study met diagnostic criteria for sarcopenia. Participants without diabetes had more often normal results in the 3 sarcopenia components than participants with diabetes [887 (80.31%) vs. 227 (72.1%), p=0.002], highlighting higher percentages of severe sarco‑penia in participants with diabetes [27 (8.6%) vs. 58 (5.2%), p=0.028]. Confirmed or severe sarcopenia was detected in 41 (13%) participants with diabetes and 109 (9.8%) participants without diabetes (p=0.108). According to BIS equa‑tion, sarcopenia was not significantly more prevalent in the more advanced stages of CKD (p=0.845). In multivariate analyses, older age (odds ratios [OR], 1.17; 95% confidence interval [CI], 1.08-1.27), and lower body mass index (OR, 0.79; 95% CI, 0.71-0.89 were associated with the presence of sarcopenia.Conclusions:One tenth of all older community‑dwelling subjects have sarcopenia. Older age and being thinner, but not worse renal function, were associated with higher prevalence of sarcopenia in older older adults with diabetes

Strutture e funzioni di una piattaforma online per gli attori della sicurezza

La presente pubblicazione riassume i risultati emersi nell’ambito del progetto di ricerca ID 19 “RLS OnLine e Picasso: la Rete per il Lavoro Sicuro italiano. Apertura al pubblico nazionale degli RLS della piattaforma informatica collaborativa per la salute e sicurezza sul lavoro per la generazione e lo scambio di nuove pratiche in materia di SSL, con l’apporto delle confederazioni comparativamente più rappresentative” finanziato dall’INAIL (Bando Bric 2019) e realizzato dall’Università degli Studi di Perugia, dall’Università degli Studi di Cagliari, dalla Fondazione Giuseppe Di Vittorio e da IAL Nazionale - Innovazione Apprendimento Lavoro s.r.l., con la partecipazione delle Organizzazioni Sindacali. Il lavoro, frutto del lavoro condiviso dell’ente finanziatore INAIL, della Fondazione Giuseppe Di Vittorio, di IAL Nazionale - Innovazione Apprendimento Lavoro s.r.l., di CGIL - Confederazione Generale Italiana del Lavoro, di CISL - Confederazione Italiana Sindacati Lavoratori, di UIL - Unione Italiana del Lavoro, e del Dipartimento di Giurisprudenza dell’Università degli Studi di Perugia, illustra la metodologia utilizzata nel corso della ricerca nonché i risultati emersi dalla stessa con particolare attenzione alle nuove esigenze degli attori della prevenzione

Ресурсоэффективные системы в управлении и контроле: взгляд в будущее (т. 2): сборник научных трудов VII Международной конференции школьников, студентов, аспирантов, молодых ученых, 8 -13 октября 2018 г., г. Томск

В сборнике представлены материалы VII Международной конференции школьников, студентов, аспирантов, молодых ученых "Ресурсоэффективные системы в управлении и контроле: взгляд в будущее". Более 500 авторов из 35 вузов, предприятий и научных исследовательских университетов России, ближнего и дальнего зарубежья представили тезисы своих докладов, в которых рассматриваются актуальные проблемы неразрушающего контроля и технической диагностики, внедрения систем менеджмента, качества образования, управления в современной экономике. Материалы предназначены для специалистов, преподавателей, аспирантов и студентов вузов, а также для всех интересующихся проблемами ресурсоэффективных технологий

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Design and methodology of the screening for CKD among older patients across Europe (SCOPE) study: A multicenter cohort observational study

Background: Decline of renal function is common in older persons and the prevalence of chronic kidney disease (CKD) is rising with ageing. CKD affects different outcomes relevant to older persons, additionally to morbidity and mortality which makes CKD a relevant health burden in this population. Still, accurate laboratory measurement of kidney function is under debate, since current creatinine-based equations have a certain degree of inaccuracy when used in the older population. The aims of the study are as follows: to assess kidney function in a cohort of 75+ older persons using existing methodologies for CKD screening; to investigate existing and innovative biomarkers of CKD in this cohort, and to align