545 research outputs found

    Contraception Use among African American and Caucasian College Students

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    Honorable Mention at the 2013 Denman Undergraduate Research ForumUnintended pregnancies, totaling nearly 3 million each year in the U.S., are associated with increased health risks for both the mother and baby. Former research has shown women of racial minorities are at disproportionally higher risks for unintended pregnancy as a result of less effective contraceptive behaviors. This study aimed to explore the differences in contraceptive behaviors amongst racial subgroups. The purpose of this secondary analysis was to analyze women’s contraceptive choices and determine if there are differences between those of African American and Caucasian women. Women (N = 196; 32% African American) ages 18 – 30 years were recruited for the parent study from a large Midwestern university through internet newsletters. Interested women contacted the PI (second author) who explained the purposes of the study. Those interested were given a secure, on-line link in which to complete informed consent and fill out the study questionnaires. For this analysis a survey using closed- and open-ended questions asking about contraceptive practices was implemented. Data were analyzed with descriptive statistics and chi-square tests. Findings indicated oral contraceptives, condoms, the morning after pill, and withdrawal were the most used by women as contraceptive methods. Additionally, the study revealed oral contraceptives use was significantly more likely by Caucasian women. Although there was not a significant relationship in this sample, results showed African American women reported using the NuvaRing® or no method more than Caucasian women. This information identifies disparities within contraceptive use and helps guide research and practice in discerning underlying mechanisms in contraceptive behaviors.No embargoAcademic Major: Nursin

    Diagnostic accuracy of calculated serum osmolarity to predict dehydration in older people: adding value to pathology lab reports

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    Objectives: To assess which osmolarity equation best predicts directly measured serum/plasma osmolality and whether its use could add value to routine blood test results through screening for dehydration in older people. Design: Diagnostic accuracy study Participants: Older people (≥65 years) in 5 cohorts: Dietary Strategies for Healthy Ageing in Europe (NU-AGE, living in the community), Dehydration Recognition In our Elders (DRIE, living in residential care), Fortes (admitted to acute medical care), Sjöstrand (emergency room) or Pfortmueller cohorts (hospitalised with liver cirrhosis). Reference standard for hydration status: Directly measured serum/plasma osmolality: current dehydration (serum osmolality >300mOsm/kg), impending/current dehydration (≥295mOsm/kg). Index tests: 39 osmolarity equations calculated using serum indices from the same blood draw as directly measured osmolality. Results: Across five cohorts 595 older people were included, of whom 19% were dehydrated (directly measured osmolality >300mOsm/kg). Of 39 osmolarity equations, five showed reasonable agreement with directly measured osmolality and three had good predictive accuracy in subgroups with diabetes and poor renal function. Two equations were characterized by narrower limits of agreement, low levels of differential bias and good diagnostic accuracy in ROC plots (areas under the curve >0.8). The best equation was osmolarity =1.86 × (Na+ + K+) + 1.15 × glucose + urea + 14 (all measured in mmol/L). It appeared useful in people aged ≥65 years with and without diabetes, poor renal function, dehydration, in men and women, with a range of ages, health, cognitive and functional status. Conclusions: Some commonly used osmolarity equations work poorly, and should not be used. Given costs and prevalence of dehydration in older people we suggest use of the best formula by pathology laboratories using a cutpoint of 295mOsm/L (sensitivity 85%, specificity 59%), to report dehydration risk opportunistically when serum glucose, urea and electrolytes are measured for other reasons in older adults

    The OSIRIS-Rex Asteroid Sample Return: Mission Operations Design

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    The OSIRIS-REx mission employs a methodical, phased approach to ensure success in meeting the missions science requirements. OSIRIS-REx launches in September 2016, with a backup launch period occurring one year later. Sampling occurs in 2019. The departure burn from Bennu occurs in March 2021. On September 24, 2023, the SRC lands at the Utah Test and Training Range (UTTR). Stardust heritage procedures are followed to transport the SRC to Johnson Space Center, where the samples are removed and delivered to the OSIRIS-REx curation facility. After a six-month preliminary examination period the mission will produce a catalog of the returned sample, allowing the worldwide community to request samples for detailed analysis.Traveling and returning a sample from an Asteroid that has not been explored before requires unique operations consideration. The Design Reference Mission (DRM) ties together space craft, instrument and operations scenarios. The project implemented lessons learned from other small body missions: APLNEAR, JPLDAWN and ESARosetta. The key lesson learned was expected the unexpected and implement planning tools early in the lifecycle. In preparation to PDR, the project changed the asteroid arrival date, to arrive one year earlier and provided additional time margin. STK is used for Mission Design and STKScheduler for instrument coverage analysis

    Magellan Project: Evolving enhanced operations efficiency to maximize science value

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    Magellan has been one of NASA's most successful spacecraft, returning more science data than all planetary spacecraft combined. The Magellan Spacecraft Team (SCT) has maximized the science return with innovative operational techniques to overcome anomalies and to perform activities for which the spacecraft was not designed. Commanding the spacecraft was originally time consuming because the standard development process was envisioned as manual tasks. The Program understood that reducing mission operations costs were essential for an extended mission. Management created an environment which encouraged automation of routine tasks, allowing staff reduction while maximizing the science data returned. Data analysis and trending, command preparation, and command reviews are some of the tasks that were automated. The SCT has accommodated personnel reductions by improving operations efficiency while returning the maximum science data possible

    Fluid Needs for Training, Competition, and Recovery in Track-and-Field Athletes

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    The 2019 International Amateur Athletics Federation Track-and-Field World Championships will take place in Qatar in the Middle East. The 2020 Summer Olympics will take place in Tokyo, Japan. It is quite likely that these events may set the record for hottest competitions in the recorded history of both the Track-and-Field World Championships and Olympic Games. Given the extreme heat in which track-and-field athletes will need to train and compete for these games, the importance of hydration is amplified more than in previous years. The diverse nature of track-and-field events, training programs, and individuality of athletes taking part inevitably means that fluid needs will be highly variable. Track-and-field events can be classified as low, moderate, or high risk for dehydration based on typical training and competition scenarios, fluid availability, and anticipated sweat losses. This paper reviews the risks of dehydration and potential consequences to performance in track-and-field events. The authors also discuss strategies for mitigating the risk of dehydration

    Hot and hypoxic environments inhibit simulated soccer performance and exacerbate performance decrements when combined.

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    The effects of heat and/or hypoxia have been well-documented in match-play data. However, large match-to-match variation for key physical performance measures makes environmental inferences difficult to ascertain from soccer match-play. Therefore, the present study aims to investigate the hot (HOT), hypoxic (HYP) and hot-hypoxic (HH) mediated-decrements during a non-motorised treadmill based soccer-specific simulation. Twelve male University soccer players completed three familiarisation sessions and four randomised crossover experimental trials of the intermittent Soccer Performance Test (iSPT) in normoxic-temperate (CON: 18oC 50% rH), HOT (30oC; 50% rH), HYP (1,000m; 18oC 50% rH) and HH (1,000m; 30oC; 50% rH). Physical performance and its performance decrements, body temperatures (rectal, skin and estimated muscle temperature), heart rate (HR), arterial blood oxygen saturation (SaO2), perceived exertion, thermal sensation (TS), body mass changes, blood lactate and plasma volume were all measured. Performance decrements were similar in HOT and HYP [Total Distance (-4%), High-speed distance (~-8%) and variable run distance (~-12%) covered] and exacerbated in HH [total distance (-9%), high-speed distance (-15%) and variable run distance (-15%)] compared to CON. Peak sprint speed, was 4% greater in HOT compared with CON and HYP and 7% greater in HH. Sprint distance covered was unchanged (p > 0.05) in HOT and HYP and only decreased in HH (-8%) compared with CON. Body mass (-2%), temperatures (+2-5%) and TS (+18%) were altered in HOT. Furthermore, SaO2 (-8%) and HR (+3%) were changed in HYP. Similar changes in body mass and temperatures, HR, TS and SaO2 were evident in HH to HOT and HYP, however, blood lactate (p < 0.001) and plasma volume (p < 0.001) were only significantly altered in HH. Perceived exertion was elevated (p < 0.05) by 7% in all conditions compared with CON. Regression analysis identified that absolute TS and absolute rise in skin and estimated muscle temperature (r = 0.82, r = 0.84 r = 0.82, respectively; p <0.05) predicted the hot-mediated-decrements in HOT. The hot, hypoxic and hot-hypoxic environments impaired physical performance during iSPT. Future interventions should address the increases in TS and body temperatures, to attenuate these decrements on soccer performance

    Exercise-heat stress with and without water replacement alters brain structures and impairs visuomotor performance

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    Effects of exercise�heat stress with and without water replacement on brain structure and visuomotor performance were examined. Thirteen healthy adults (23.6 ± 4.2 years) completed counterbalanced 150 min trials of exercise�heat stress (45°C, 15% RH) with water replacement (EHS) or without (~3% body mass loss; EHS�DEH) compared to seated rest (CON). Anatomical scans and fMRI Blood�Oxygen�Level�Dependent responses during a visuomotor pacing task were evaluated. Accuracy decreased (P 0.50) between structural changes and visuomotor accuracy. EHS�DEH increased neural activation (P < 0.05) within motor and visual areas versus EHS and CON. Brain structural changes are related to bidirectional plasma osmolality perturbations resulting from exercise�heat stress (with and without water replacement), but do not explain visuomotor impairments. Negative impacts of exercise�heat stress on visuomotor tasks are further exacerbated by dehydration

    Wicked Good Sports Medicine Symposium 2012 Program

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    2012 sports medicine symposium at the University of New England in Biddeford, Maine. Presenters and topics included: Daniel E. Lieberman: Why Exercise Really is Medicine (An Evolutionary Explanation); Samuel Headley: Exercise and Chronic Kidney Disease; Stella L. Volpe: Prevention of Weight Gain in a Large Portion Society; J. Timothy Lightfoot: Can You Be Born a Couch Potato? The Genetics that Control Your Physical Activity; Samuel N. Cheuvront: Answers to 10 Common Questions about Hydration; David Epstein: Missing the Phenotypes for the Genotypes.https://dune.une.edu/wgsms/1000/thumbnail.jp

    Water-loss (intracellular) dehydration assessed using urinary tests, how well do they work? Diagnostic accuracy in older people

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    Background: Water-loss dehydration (hypertonic, hyperosmotic or intra-cellular dehydration) is due to insufficient fluid intake and distinct from hypovolemia due to excess fluid losses. It is associated with poor health outcomes such as disability and mortality in older people. Urine specific gravity (USG), color and urine osmolality have been widely advocated for screening for dehydration in older adults. Objective: To assess the diagnostic accuracy of urinary measures to screen for water-loss dehydration in older people.Design: This was a diagnostic accuracy study of people aged ≥65years taking part in the Dehydration Recognition In our Elders (DRIE, living in long-term care) or Dietary Strategies for Healthy Ageing in Europe (NU-AGE, living in the community) studies. The reference standard was serum osmolality, index tests included USG, urine color, osmolality, cloudiness, additional dipstick measures, ability to provide a urine sample, and volume of a random urine sample. Minimum useful diagnostic accuracy was set at sensitivity and specificity ≥70% or receiver operating characteristics plot area under the curve ≥0.70. Results: DRIE participants (67% women, mean age 86 years, n=162) had more limited cognitive and functional abilities than NU-AGE participants (64% women, mean age 70 years, n=151). 19% of DRIE and 22% of NU-AGE participants were dehydrated (serum osmolality >300mOsm/kg). Neither USG nor any other potential urinary tests were usefully diagnostic for water-loss dehydration. Conclusions: Although USG, urine color and urinary osmolality have been widely advocated for screening for dehydration in older adults, we show in the largest study to date that their diagnostic accuracy is too low to be useful and these measures should not be used to indicate hydration status in older people (either alone or as part of a wider tranche of tests). There is a need to develop simple, inexpensive and non-invasive tools for the assessment of dehydration in older people
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