10 research outputs found
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Inkjet Printing for Biosensing and Security Applications
The adaptation of inkjet printing technology has recently been used to create controlled high throughput micro- and nano-scaled structures. Coupling this technique with gold nanoparticles in our research has produced new platforms for biosensors, chemical patterning, and anti-counterfeiting applications. In this presentation, we will highlight promising fabrication strategies including the development of test strips for the determination of bacteria in drinking water as well as the use of patterned nanoparticles for security applications
Solvatochromic probes for detecting hydrogen-bond-donating solvents
Hydrogen bonding heavily influences conformations, rate of reactions, and chemical equilibria. The development of a method to monitor hydrogen bonding interactions independent of polarity is challenging as both are linked. We have developed two solvatochromic dyes that detect hydrogen-bond-donating solvents. The unique solvatochromism of the triazine architecture has allowed the development of probes that monitor hydrogen-bond-donating species including water
Detection of Bacteria Using Inkjet-Printed Enzymatic Test Strips
Low-cost diagnostics for drinking
water contamination have the
potential to save millions of lives. We report a method that uses
inkjet printing to copattern an enzyme–nanoparticle sensor
and substrate on a paper-based test strip for rapid detection of bacteria.
A colorimetric response is generated on the paper substrate that allows
visual detection of contamination without the need for expensive instrumentation.
These strips demonstrate a viable nanomanufacturing strategy for low-cost
bacterial detection
Gradient and Patterned Protein Films Stabilized via Nanoimprint Lithography for Engineered Interactions with Cells
Protein-based biomaterials provide
versatile scaffolds for generating
functional surfaces for biomedical applications. However, tailoring
the functional and biological properties of protein films remains
a challenge. Here, we describe a high-throughput method to designing
stable, functional biomaterials by combining inkjet deposition of
protein inks with a nanoimprint lithography based methodology. The
translation of the intrinsically charged proteins into functional
materials properties was demonstrated through controlled cellular
adhesion. This modular strategy offers a rapid method to produce customizable
biomaterials
Gold nanoparticles: preparation, properties, and applications in bionanotechnology
Gold nanoparticles (AuNPs) are important components for biomedical applications. AuNPs have been widely employed for diagnostics, and have seen increasing use in the area of therapeutics. In this mini-review, we present fabrication strategies for AuNPs and highlight a selection of recent applications of these materials in bionanotechnology