Lesões de pele solares: características clínicas e sociodemográficas entre moradores de uma cidade agrícola do sul de Santa Catarina: Solar induced skin lesions: Clinical and demographic characteristics among inhabitants of a rural city in southern Santa Catarina State

FUNDAMENTOS: A exposição solar pode ocasionar efeitos patológicos à pele. OBJETIVOS: Verificar as características clínicas e sociodemográficas das lesões de pele solares entre moradores de uma cidade agrícola da região sul de Santa Catarina. MÉTODOS: Estudo transversal com coleta de dados sociodemográficos primários e avaliação dermatológica. A análise estatística foi desenvolvida pelo software IBM SPSS versão 22.0 e confiança de 95%, sendo aplicadas frequências absoluta e relativa, média, desvio padrão, teste de Shapiro Wilk, qui-quadrado de Pearson e Exato de Fisher. RESULTADOS: Incluso 99 pacientes com média de idade de 50,13 anos sendo a maioria mulheres, agricultores, de ensino fundamental incompleto, descendência italiana, cor da pele branca, fototipos II e III, cabelos e olhos castanhos e sem história pessoal e familiar de neoplasia cutânea. Havia história de exposição solar diária e queimadura solar em outros momentos da vida. Verificou-se a predominância de lesões solares não neoplásicas em costas, membros superiores e inferiores. As lesões pré-neoplásicas prevaleceram em nariz, região próxima aos olhos, lábios e orelha; as neoplásicas em nariz, lábio, orelha e tronco. Ocorreu relação estatisticamente significativa entre fototipo de pele II e lesão pré-neoplásica (p<0,001). LIMITAÇÕES DO ESTUDO: Viés de memória relacionado à história clínica pregressa e história familiar.CONCLUSÕES: O fototipo de pele II demonstrou relação estatística significativa à presença das lesões pré-neoplásicas (p<0,001). Topograficamente, estas lesões, assim como as neoplásicas, concentraram-se na região cefálica. A etnia não teve relevância no desenvolvimento de lesões de pele solares

Análise da demanda ambulatorial de fotodermatoses pré-malignas e malignas em uma universidade do sul catarinense

Objetivo: Conhecer a frequência das principais lesões de pele pré-cancerosas e malignas, em pacientes que recebem atendimento de dermatologia no Ambulatório das Clínicas Integradas de uma universidade do sul catarinense. Metodologia: Foi realizado um estudo observacional, descritivo, retrospectivo, com coleta de dados secundários e abordagem quantitativa. Foram analisados 80 prontuários de pacientes de ambos os sexos atendidos entre 2017 e 2018. Resultados: Foi encontrada uma frequência de 62,5% (n=50) das doenças malignas e pré-malignas de pele no sexo feminino, sendo que a idade média do início das lesões foi de 62,80±10,11 anos. A maioria dos pacientes pesquisados eram aposentados 38,4% (n=28), do lar 13,7% (n=10) e autônomos 11% (n=8), de forma que 100% (n=59) pertenciam a raça branca. Quanto a hipótese diagnóstica, a ceratose actínica correspondeu a 59,41% (n=60), seguida pelo carcinoma basocelular com 26,73% (n=27), carcinoma espinocelular com 7,92% (n=8) e melanoma com 5,94% (n=6), sendo que a localização preferencial das lesões foi na face 52,21% (n=59), com os membros representando 29,20% (n=33) e o tronco 18,58% (n=21). O tratamento iniciado foi na maior parte das vezes a exérese, em 47,4% (n=37) dos indivíduos, seguida pela medicação tópica com 39,7% (n=31) e ambos ocorreram em 12,8% (n=10). Conclusão: O perfil prevalente encontrado no ambulatório de dermatologia analisado foi de pacientes do sexo feminino (62,5%), com uma idade média de início dos sintomas de 62,8 ± 10,11 anos, sendo 100% pertencentes à raça branca. A classe de hipótese diagnóstica mais encontrada foi a de ceratose actínica (59,41%), e dentre as neoplasias malignas o carcinoma basocelular se destacou, com 26,73% dos casos, sendo que 52,21% das lesões foram encontradas em face, e em 47,4% a exérese foi o tratamento de eleição destas patologias

Updated cardiovascular prevention guideline of the Brazilian Society of Cardiology: 2019

Sem informação113478788

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

Electroweak production of two jets in association with a Z boson in proton-proton collisions root s =13 TeV

A measurement of the electroweak (EW) production of two jets in association with a Z boson in proton-proton collisions at root s = 13 TeV is presented, based on data recorded in 2016 by the CMS experiment at the LHC corresponding to an integrated luminosity of 35.9 fb(-1). The measurement is performed in the lljj final state with l including electrons and muons, and the jets j corresponding to the quarks produced in the hard interaction. The measured cross section in a kinematic region defined by invariant masses m(ll) > 50 GeV, m(jj) > 120 GeV, and transverse momenta P-Tj > 25 GeV is sigma(EW) (lljj) = 534 +/- 20 (stat) fb (syst) fb, in agreement with leading-order standard model predictions. The final state is also used to perform a search for anomalous trilinear gauge couplings. No evidence is found and limits on anomalous trilinear gauge couplings associated with dimension-six operators are given in the framework of an effective field theory. The corresponding 95% confidence level intervals are -2.6 <cwww/Lambda(2) <2.6 TeV-2 and -8.4 <cw/Lambda(2) <10.1 TeV-2. The additional jet activity of events in a signal-enriched region is also studied, and the measurements are in agreement with predictions.Peer reviewe

Measurement of nuclear modification factors of gamma(1S)), gamma(2S), and gamma(3S) mesons in PbPb collisions at root s(NN)=5.02 TeV

The cross sections for ϒ(1S), ϒ(2S), and ϒ(3S) production in lead-lead (PbPb) and proton-proton (pp) collisions at √sNN = 5.02 TeV have been measured using the CMS detector at the LHC. The nuclear modification factors, RAA, derived from the PbPb-to-pp ratio of yields for each state, are studied as functions of meson rapidity and transverse momentum, as well as PbPb collision centrality. The yields of all three states are found to be significantly suppressed, and compatible with a sequential ordering of the suppression, RAA(ϒ(1S)) > RAA(ϒ(2S)) > RAA(ϒ(3S)). The suppression of ϒ(1S) is larger than that seen at √sNN = 2.76 TeV, although the two are compatible within uncertainties. The upper limit on the RAA of ϒ(3S) integrated over pT, rapidity and centrality is 0.096 at 95% confidence level, which is the strongest suppression observed for a quarkonium state in heavy ion collisions to date. © 2019 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). Funded by SCOAP3.Peer reviewe

Measurement of the Splitting Function in &ITpp &ITand Pb-Pb Collisions at root&ITsNN&IT=5.02 TeV

Data from heavy ion collisions suggest that the evolution of a parton shower is modified by interactions with the color charges in the dense partonic medium created in these collisions, but it is not known where in the shower evolution the modifications occur. The momentum ratio of the two leading partons, resolved as subjets, provides information about the parton shower evolution. This substructure observable, known as the splitting function, reflects the process of a parton splitting into two other partons and has been measured for jets with transverse momentum between 140 and 500 GeV, in pp and PbPb collisions at a center-of-mass energy of 5.02 TeV per nucleon pair. In central PbPb collisions, the splitting function indicates a more unbalanced momentum ratio, compared to peripheral PbPb and pp collisions.. The measurements are compared to various predictions from event generators and analytical calculations.Peer reviewe

An embedding technique to determine ττ backgrounds in proton-proton collision data

An embedding technique is presented to estimate standard model tau tau backgrounds from data with minimal simulation input. In the data, the muons are removed from reconstructed mu mu events and replaced with simulated tau leptons with the same kinematic properties. In this way, a set of hybrid events is obtained that does not rely on simulation except for the decay of the tau leptons. The challenges in describing the underlying event or the production of associated jets in the simulation are avoided. The technique described in this paper was developed for CMS. Its validation and the inherent uncertainties are also discussed. The demonstration of the performance of the technique is based on a sample of proton-proton collisions collected by CMS in 2017 at root s = 13 TeV corresponding to an integrated luminosity of 41.5 fb(-1).Peer reviewe