Effect of salinomycin and tiamulin association in broiler chicken diets

A seven week floor pen trial in boxes (1,8 x 1,7 m) were conducted with 648 male and 648 female commercial Ross broilers to determine the effects of association of constant level (60 ppm) of Salinomycin and six levels (0; 10; 15; 20; 30 and 40 ppm) of Tiamulin, in six replications of 36 birds each. The rations for all treatments from 1-11, 12-23, 24-44 and 45-49 days attended the needs according to the NRC-1984 specification. All drugs were withdrawn for the four days pryor to slaughter. Body weights, feed intake and efficiency were recorded at 23 and 49 days of age. Mortality was determined at 49 days of age. When chickens were 1, 35 and 45 days old eighteen birds from each treatment were randomly collected and tested sorologically for Mycoplasma sp. At this same age six birds from each treatment were taked randomly necropsied and submited to score evaluation for macro and microscopic lesions. The differences among treatments were not statistically significant (P>0.05) for any paramethers studies and with the following means: Body weight at 23 days (797.9 g) and 49 days (2,247.0 g). Average daily weight gain (45.0 g). Feed consumption 23 days (1,164 g) and 49 days (4,321 g). Feed efficiency 23 days (1.45) and 49 days (1.92) and mortality 49 days (6.7%). All samples presented no lesions and were negative for Mycoplasma galissepticum rapid soroaglulination. No detrimental effects were observed in broiler performance due to the association of salinomycin (60 ppm) and tiamulin (10 a 40 ppm).A pesquisa foi conduzida no Aviário Experimental do Departamento de Produção Animal da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo, em Pirassununga, São Paulo, e teve a finalidade de verificar a possível toxicidade do anticoccidiano salinomicina pela administração simultânea do antibiótico tiamulin na ração. Foram utilizados 1.296 pintos de 01 dia, distribuídos em 36 boxes experimentais e submetidos a 6 tratamentos, com 6 repetições de 36 aves cada. O delineamento experimental foi o de blocos casualizados. Para os tratamentos foram empregados 60 ppm de salinomicina e 0; 10; 15; 20; 30 e 40 ppm de tiamulin. Os dados obtidos indicaram não haver depressão no crescimento das aves, nem tampouco no consumo de ração e conversão alimentar. Não ocorreram lesões nos sacos aéreos e os testes de soroaglutinação rápida para Mycoplasma gallissepticum apresentaram resultados negativos. Tendo em vista os resultados obtidos, pode-se dizer que a adição simultânea de tiamulin e salinomicina em rações de aves para corte, nos níveis utilizados, não acarreta toxicidade

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Associação entre salinomicina e tiamulin em rações de aves para corte

A pesquisa foi conduzida no Aviário Experimental do Departamento de Produção Animal da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo, em Pirassununga, São Paulo, e teve a finalidade de verificar a possível toxicidade do anticoccidiano salinomicina pela administração simultânea do antibiótico tiamulin na ração. Foram utilizados 1.296 pintos de 01 dia, distribuídos em 36 boxes experimentais e submetidos a 6 tratamentos, com 6 repetições de 36 aves cada. O delineamento experimental foi o de blocos casualizados. Para os tratamentos foram empregados 60 ppm de salinomicina e 0; 10; 15; 20; 30 e 40 ppm de tiamulin. Os dados obtidos indicaram não haver depressão no crescimento das aves, nem tampouco no consumo de ração e conversão alimentar. Não ocorreram lesões nos sacos aéreos e os testes de soroaglutinação rápida para Mycoplasma gallissepticum apresentaram resultados negativos. Tendo em vista os resultados obtidos, pode-se dizer que a adição simultânea de tiamulin e salinomicina em rações de aves para corte, nos níveis utilizados, não acarreta toxicidade

Measurements of ttˉt\bar{t} differential cross-sections of highly boosted top quarks decaying to all-hadronic final states in pppp collisions at s=13 \sqrt{s}=13\, TeV using the ATLAS detector

Measurements are made of differential cross-sections of highly boosted pair-produced top quarks as a function of top-quark and $t\bar{t}$ system kinematic observables using proton--proton collisions at a center-of-mass energy of $\sqrt{s} = 13$ TeV. The data set corresponds to an integrated luminosity of $36.1$ fb$^{-1}$, recorded in 2015 and 2016 with the ATLAS detector at the CERN Large Hadron Collider. Events with two large-radius jets in the final state, one with transverse momentum $p_{\rm T} > 500$ GeV and a second with $p_{\rm T}>350$ GeV, are used for the measurement. The top-quark candidates are separated from the multijet background using jet substructure information and association with a $b$-tagged jet. The measured spectra are corrected for detector effects to a particle-level fiducial phase space and a parton-level limited phase space, and are compared to several Monte Carlo simulations by means of calculated $\chi^2$ values. The cross-section for $t\bar{t}$ production in the fiducial phase-space region is $292 \pm 7 \ \rm{(stat)} \pm 76 \rm{(syst)}$ fb, to be compared to the theoretical prediction of $384 \pm 36$ fb

Measurements of ttˉt\bar{t} differential cross-sections of highly boosted top quarks decaying to all-hadronic final states in pppp collisions at s=13 \sqrt{s}=13\, TeV using the ATLAS detector

Measurements are made of differential cross-sections of highly boosted pair-produced top quarks as a function of top-quark and $t\bar{t}$ system kinematic observables using proton--proton collisions at a center-of-mass energy of $\sqrt{s} = 13$ TeV. The data set corresponds to an integrated luminosity of $36.1$ fb$^{-1}$, recorded in 2015 and 2016 with the ATLAS detector at the CERN Large Hadron Collider. Events with two large-radius jets in the final state, one with transverse momentum $p_{\rm T} > 500$ GeV and a second with $p_{\rm T}>350$ GeV, are used for the measurement. The top-quark candidates are separated from the multijet background using jet substructure information and association with a $b$-tagged jet. The measured spectra are corrected for detector effects to a particle-level fiducial phase space and a parton-level limited phase space, and are compared to several Monte Carlo simulations by means of calculated $\chi^2$ values. The cross-section for $t\bar{t}$ production in the fiducial phase-space region is $292 \pm 7 \ \rm{(stat)} \pm 76 \rm{(syst)}$ fb, to be compared to the theoretical prediction of $384 \pm 36$ fb