242 research outputs found
Failure of Brown representability in derived categories
Let T be a triangulated category with coproducts, C the full subcategory of
compact objects in T. If T is the homotopy category of spectra, Adams proved
the following in [Adams71]: All contravariant homological functors C --> Ab are
the restrictions of representable functors on T, and all natural
transformations are the restrictions of morphisms in T.
It has been something of a mystery, to what extent this generalises to other
triangulated categories. In [Neeman97], it was proved that Adams' theorem
remains true as long as C is countable, but can fail in general. The failure
exhibited was that there can be natural transformations not arising from maps
in T. A puzzling open problem remained: Is every homological functor the
restriction of a representable functor on T? In a recent paper, Beligiannis
made some progress. But in this article, we settle the problem. The answer is
no. There are examples of derived categories T = D(R) of rings, and
contravariant homological functors C --> Ab which are not restrictions of
representables.Comment: 22 pages, to appear in Topology. http://jdc.math.uwo.ca Lots of minor
revisions. This version should closely match the published versio
Derived Categories of Coherent Sheaves and Triangulated Categories of Singularities
In this paper we establish an equivalence between the category of graded
D-branes of type B in Landau-Ginzburg models with homogeneous superpotential W
and the triangulated category of singularities of the fiber of W over zero. The
main result is a theorem that shows that the graded triangulated category of
singularities of the cone over a projective variety is connected via a fully
faithful functor to the bounded derived category of coherent sheaves on the
base of the cone. This implies that the category of graded D-branes of type B
in Landau-Ginzburg models with homogeneous superpotential W is connected via a
fully faithful functor to the derived category of coherent sheaves on the
projective variety defined by the equation W=0.Comment: 26 pp., LaTe
Foster youth and drug use:Exploring risk and protective factors
Substance use and misuse experiences of foster youth remain an under-researched area. Given that early use of drugs is said to be a common factor among 90% of those who develop substance misuse problems in their lifetime, this is an important area of academic study (. Dennis, White, & Ives, 2009). By drawing upon primary empirical data from a mixed-methods study, this paper addresses an important gap in the literature and seeks to provide an improved understanding of foster youth, drug use and vulnerability. A total of 261 foster youth, who had exited care, contributed to a quantitative survey, and a further 35 provided qualitative narratives of their lived experience. Key risk factors including experience of homelessness, school exclusion and living setting are identified as strong influences that predict high levels of drug use among foster youth. Targeted social support and interventions in the form of pre-leaving care in the context of a strong practitioner/youth relationship are suggested to help ameliorate poor outcomes to obviate the problem of substance misuse among foster youth
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Rapid prototyping of patterned functional nanostructures
Living systems exhibit form and function on multiple length scales, and the prospect of imparting life-like qualities to man-made materials has inspired many recent efforts to devise hierarchical materials assembly strategies. For example, Yang et al. grew surfactant-templated mesoporous silica on hydrophobic patterns prepared by micro-contact printing {micro}CP{sup 3}. Trau et al. formed oriented mesoporous silica patterns, using a micro-molding in capillaries MIMIC technique, and Yang et al. combined MIMIC, polystyrene sphere templating, and surfactant-templating to create oxides with three levels of structural order. Overall, great progress has been made to date in controlling structure on scales ranging from several nanometers to several micrometers. However, materials prepared have been limited to oxides with no specific functionality, whereas for many of the envisioned applications of hierarchical materials in micro-systems, sensors, waveguides, photonics, and electronics, it is necessary to define both form and function on several length scales. In addition, the patterning strategies employed thus far require hours or even days for completion. Such slow processes are inherently difficult to implement in commercial environments. The authors have combined evaporation-induced (silica/surfactant) self-assembly EISA with rapid prototyping techniques like pen lithography, ink-jet printing, and dip-coating on micro-contact printed substrates to form hierarchically organized structures in seconds. In addition, by co-condensation of tetrafunctional silanes (Si(OR){sub 4}) with tri-functional organosilanes ((RO){sub 3}SiR{prime}){sup 12--14} or by inclusion of organic additives, the authors have selectively derivatized the silica framework with functional R{prime} ligands or molecules. The resulting materials exhibit form and function on multiple length scales: on the molecular scale, functional organic moieties are positioned on pore surfaces, on the mesoscale, monosized pores are organized into 1-, 2-, or 3-dimensional networks, providing size-selective accessibility from the gas or liquid phase, and on the macroscale, 2-dimensional arrays and fluidic or photonic systems may be defined
Theory and phenomenology of two-Higgs-doublet models
We discuss theoretical and phenomenological aspects of two-Higgs-doublet
extensions of the Standard Model. In general, these extensions have scalar
mediated flavour changing neutral currents which are strongly constrained by
experiment. Various strategies are discussed to control these flavour changing
scalar currents and their phenomenological consequences are analysed. In
particular, scenarios with natural flavour conservation are investigated,
including the so-called type I and type II models as well as lepton-specific
and inert models. Type III models are then discussed, where scalar flavour
changing neutral currents are present at tree level, but are suppressed by
either specific ansatze for the Yukawa couplings or by the introduction of
family symmetries. We also consider the phenomenology of charged scalars in
these models. Next we turn to the role of symmetries in the scalar sector. We
discuss the six symmetry-constrained scalar potentials and their extension into
the fermion sector. The vacuum structure of the scalar potential is analysed,
including a study of the vacuum stability conditions on the potential and its
renormalization-group improvement. The stability of the tree level minimum of
the scalar potential in connection with electric charge conservation and its
behaviour under CP is analysed. The question of CP violation is addressed in
detail, including the cases of explicit CP violation and spontaneous CP
violation. We present a detailed study of weak basis invariants which are odd
under CP. A careful study of spontaneous CP violation is presented, including
an analysis of the conditions which have to be satisfied in order for a vacuum
to violate CP. We present minimal models of CP violation where the vacuum phase
is sufficient to generate a complex CKM matrix, which is at present a
requirement for any realistic model of spontaneous CP violation.Comment: v3: 180 pages, 506 references, new chapter 7 with recent LHC results;
referee comments taken into account; submitted to Physics Report
Status of Muon Collider Research and Development and Future Plans
The status of the research on muon colliders is discussed and plans are
outlined for future theoretical and experimental studies. Besides continued
work on the parameters of a 3-4 and 0.5 TeV center-of-mass (CoM) energy
collider, many studies are now concentrating on a machine near 0.1 TeV (CoM)
that could be a factory for the s-channel production of Higgs particles. We
discuss the research on the various components in such muon colliders, starting
from the proton accelerator needed to generate pions from a heavy-Z target and
proceeding through the phase rotation and decay ()
channel, muon cooling, acceleration, storage in a collider ring and the
collider detector. We also present theoretical and experimental R & D plans for
the next several years that should lead to a better understanding of the design
and feasibility issues for all of the components. This report is an update of
the progress on the R & D since the Feasibility Study of Muon Colliders
presented at the Snowmass'96 Workshop [R. B. Palmer, A. Sessler and A.
Tollestrup, Proceedings of the 1996 DPF/DPB Summer Study on High-Energy Physics
(Stanford Linear Accelerator Center, Menlo Park, CA, 1997)].Comment: 95 pages, 75 figures. Submitted to Physical Review Special Topics,
Accelerators and Beam
Burden of anemia in patients with osteoarthritis and rheumatoid arthritis in French secondary care
<p>Abstract</p> <p>Background</p> <p>Arthritic disorders can be the cause of hospitalizations, especially among individuals 60 years and older. The objective of this study is to investigate associations between health care resource utilization in arthritis patients with and without concomitant anemia in a secondary care setting in France.</p> <p>Methods</p> <p>This retrospective cohort study utilized data on secondary care activity in 2001 from the Programme de Médicalisation des Systèmes d'Information database. Two cohorts were defined using ICD-10 codes: patients with an arthritis diagnosis with a concomitant diagnosis of anemia; and arthritis patients without anemia. Health care resource utilization for both populations was analyzed separately in public and private hospitals. Study outcomes were compared between the cohorts using standard bivariate and multivariable methods.</p> <p>Results</p> <p>There were 300,865 hospitalizations for patients with arthritis only, and 2,744 for those with concomitant anemia. Over 70% of patients with concomitant anemia were in public hospitals, compared with 53.5% of arthritis-only patients. Arthritis patients without anemia were younger than those with concomitant anemia (mean age 66.7 vs 74.6, public hospitals; 67.1 vs 72.2, private hospitals). Patients with concomitant anemia/arthritis only had a mean length of stay of 11.91 (SD 14.07)/8.04 (SD 9.93) days in public hospitals, and 10.68 (SD 10.16)/9.83 (SD 7.76) days in private hospitals. After adjusting for confounders, the mean (95% CI) additional length of stay for arthritis patients with concomitant anemia, compared with those with arthritis only, was 1.56 (1.14-1.98) days in public and 0.69 (0.22-1.16) days in private hospitals. Costs per hospitalization were €;480 (227-734) greater for arthritis patients with anemia in public hospitals, and €;30 (-113-52) less in private hospitals, than for arthritis-only patients.</p> <p>Conclusions</p> <p>Arthritis patients with concomitant anemia have a longer length of stay, undergo more procedures, and have higher hospitalization costs than nonanemic arthritis patients in public hospitals in France. In private hospitals, concomitant anemia was associated with modest increases in length of stay and number of procedures; however, this did not translate into higher costs. Such evidence of anemia-related health care utilization and costs can be considered as a proxy for the clinical significance of anemia.</p
Simulations of Supercollider Physics
The Standard Model of particle physics makes it possible to simulate complete
events for physics signatures and their backgrounds in high energy collisions.
Knowledge of how the produced particles interact with the materials in a
detector makes it possible to simulate the response of any particular detector
design to these events and so determine whether the detector could observe the
signal. The combination of these techniques has played an important role in the
design of new detectors, particularly those for hadron supercolliders where the
high rates and small signal cross sections make the experiments very difficult.
The technique is reviewed here and illustrated using the simulations of the GEM
detector proposed for the Superconducting Super Collider. Although the
simulations and results described here are somewhat detector-specific, we
believe that they can serve as a useful model for this component of detector
design for future hadron supercolliders.Comment: 99 pages, Plain TeX (macros included), includes gzipped tar file with
56/60 EPS figures for dvips. Get complete version from
http://penguin.phy.bnl.gov/www/hetpapers.html or
ftp://penguin.phy.bnl.gov/pub/papers/gemreview.ps.
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