Hybrid Structures for Piezoelectric Nanogenerators: Fabrication Methods, Energy Generation, and Self-Powered Applications

Smart energy harvesting through the surrounding environment generates sufficient energy to drive the low-power consumption systems. It is the forthcoming revolution in smart (or self-powered) technology and results in abolishing the usage of complex batteries, external circuit components, and natural sources. To date, extensive fabrication methods, the growth of ZnO nanostructures on plastic substrates, and flexible piezoelectric polymer film-based devices were tested to improve the performance of piezoelectric nanogenerator (PNG) as a prominent energy-harnessing approach for the development of sustainable independent power sources. Still, PNG technology suffers from brittleness, leakage current issues, high electrical output generation, and long-term durability, which can be possible to control by the composite technology, that is, polymer/nanoparticles. The objective of this book chapter determines the rapid growth of multifunctional, flexible composite structures through various methods (e.g., ionotropic gelation method, groove technique, ultrasonication followed by solution-casting methods) for high output energy generation and self-powered sensor/system studies

Proper qq-caterpillars are distinguished by their Chromatic Symmetric Functions

Stanley's Tree Isomorphism Conjecture posits that the chromatic symmetric function can distinguish non-isomorphic trees. While already established for caterpillars and other subclasses of trees, we prove the conjecture's validity for a new class of trees that generalize proper caterpillars, thus confirming the conjecture for a broader class of trees.Comment: 11 page

Wear Analysis on Silicon Carbide Coated HSS Pin on SS Disc Substrate

AbstractWear takes predominant role in reducing the cutting life time of tool materials. This investigation focuses on the influence of Silicon Carbide nanocoating on the HSS tool material. Silicon carbide powder was coated on the high speed steel pin by using physical vapour deposition (PVD) technique. The stainless steel was selected as a work piece material. The performance parameters like volume loss, wear rate, stresses developed and temperature rise were compared between coated high speed steel pin and uncoated high speed steel pin upon machining the stainless steel disc. The performance parameters were calculated by using coefficient of friction values which were obtained from the pin on disc test. Substantial resistance to wear has been achieved by the coating. Scanning electron microscope (SEM) Analysis and Energy dispersive analysis by X-ray (EDAX) were used as characterization techniques

Triboelectric Nanogenerators: Design, Fabrication, Energy Harvesting, and Portable-Wearable Applications

Scavenging energy from our day-to-day activity into useful electrical energy be the best solution to solve the energy crisis. This concept entirely reduces the usage of batteries, which have a complex issue in recycling and disposal. For electrical harvesting energy from vibration energy, there are few energy harvesters available, but the fabrication, implementation, and maintenances are quite complicated. Triboelectric nanogenerators (TENG) having the advantage of accessible design, less fabrication cost, and high energy efficiency can replace the battery in low-power electronic devices. TENGs can operate in various working modes such as contact-separation mode, sliding mode, single-electrode mode, and free-standing mode. The design of TENGs with the respective operating modes employed in generating electric power as well as can be utilized as a portable and wearable power source. The fabrication of triboelectric layers with micro-roughness could enhance the triboelectric charge generation. The objective of this chapter is to deal with the design of triboelectric layers, creating micro structured roughness using the soft-lithographic technique, fabrication of TENGs using different working modes, energy harvesting performance analysis, powering up commercial devices (LEDs, displays, and capacitors), and portable-wearable applications

Prevalence of macrolide resistance and in vitro activities of six antimicrobial agents against clinical isolates of streptococcus pneumoniae from a multi-center surveillance in Malaysia

The in vitro activities of 6 antimicrobial agents against clinical isolates of Streptococcus pneumoniae (pneumococci) were investigated and the erythromycin minimum inhibitory concentrations (MICs) were correlated with the two major macrolide resistance determinants, mef(A) and erm(B). MICs of commonly used antibiotics as well as the presence of macrolide resistance determinant genes in all isolates were tested. Seventy one pneumococcal isolates collected at Institute for Medical Research (IMR) were included in this study. Phenotypic characterization, MIC determination using E-test strips and polymerase chain reactions for antibiotic resistance determination were included. Among the isolates, 25 (35.2%) isolates were erythromycin susceptible, 3 (4.2%) were intermediate and 42 (60.6%) were resistant. Fifty three isolates (74.7%) were found with mef(A) alone, 15 (21.1%) isolates with erm(B) + mef(A) combination and 3 (4.2%) isolates with none of the two genes. The in vitro activity of penicillin, amoxicillin clavulanic acid, ceftriaxone and cefotaxime is superior to trimethoprim-sulfamethoxazole and erythromycin. In conclusion, pneumococcal isolates in this study were highly susceptible to penicillin with very low MICs. However, a very high prevalence rate of erythromycin resistance was observed. Erythromycin resistant S. pneumoniae isolates with both mef(A) and erm(B) showed very high MICs ≥256 μg/mL

Genetic analysis of scattered populations of the Indian eri silkworm, Samia cynthia ricini Donovan: Differentiation of subpopulations

Deforestation and exploitation has led to the fragmentation of habitats and scattering of populations of the economically important eri silkworm, Samia cynthia ricini, in north-east India. Genetic analysis of 15 eri populations, using ISSR markers, showed 98% inter-population, and 23% to 58% intra-population polymorphism. Nei’s genetic distance between populations increased significantly with altitude (R2 = 0.71) and geographic distance (R2 = 0.78). On the dendrogram, the lower and upper Assam populations were clustered separately, with intermediate grouping of those from Barpathar and Chuchuyimlang, consistent with geographical distribution. The Nei’s gene diversity index was 0.350 in total populations and 0.121 in subpopulations. The genetic differentiation estimate (Gst) was 0.276 among scattered populations. Neutrality tests showed deviation of 118 loci from Hardy-Weinberg equilibrium. The number of loci that deviated from neutrality increased with altitude (R2 = 0.63). Test of linkage disequilibrium showed greater contribution of variance among eri subpopulations to total variance. D’2IS exceeded D’2ST, showed significant contribution of random genetic drift to the increase in variance of disequilibrium in subpopulations. In the Lakhimpur population, the peripheral part was separated from the core by a genetic distance of 0.260. Patchy habitats promoted low genetic variability, high linkage disequilibrium and colonization by new subpopulations. Increased gene flow and habitat-area expansion are required to maintain higher genetic variability and conservation of the original S. c. ricini gene pool

Design of bio-nanosystems for oral delivery of functional compounds

Nanotechnology has been referred to as one of the most interesting topics in food technology due to the potentialities of its use by food industry. This calls for studying the behavior of nanosystems as carriers of biological and functional compounds aiming at their utilization for delivery, controlled release and protection of such compounds during food processing and oral ingestion. This review highlights the principles of design and production of bio-nanosystems for oral delivery and their behavior within the human gastrointestinal (GI) tract, while providing an insight into the application of reverse engineering approach to the design of those bio-nanosystems. Nanocapsules, nanohydrogels, lipid-based and multilayer nanosystems are discussed (in terms of their main ingredients, production techniques, predominant forces and properties) and some examples of possible food applications are given. Phenomena occurring in in vitro digestion models are presented, mainly using examples related to the utilization of lipid-based nanosystems and their physicochemical behavior throughout the GI tract. Furthermore, it is shown how a reverse engineering approach, through two main steps, can be used to design bio-nanosystems for food applications, and finally a last section is presented to discuss future trends and consumer perception on food nanotechnology.Miguel A. Cerqueira, Ana C. Pinheiro, Helder D. Silva, Philippe E. Ramos, Ana I. Bourbon, Oscar L. Ramos (SFRH/BPD/72753/2010, SFRH/BD/48120/2008, SFRH/BD/81288/2011, SFRH/BD/80800/2011, SFRH/BD/73178/2010 and SFRH/BPD/80766/2011, respectively) are the recipients of a fellowship from the Fundacao para a Ciencia e Tecnologia (FCT, POPH-QREN and FSE Portugal). Maria L. Flores-Lopez thanks Mexican Science and Technology Council (CONACYT, Mexico) for PhD fellowship support (CONACYT Grant number: 215499/310847). The support of EU Cost Actions FA0904 and FA1001 is gratefully acknowledged

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025. Prevalence of overweight increased from 5.2% (30 (22.8–38.5) million) in 2000 to 6.0% (55.5 (44.8–67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

Exploring the Landscape of Teaching and Learning English as a Second Language in India

This systematic review examines the challenges, opportunities, and ways forward for teaching and learning English as a second language in India. The study explores the current landscape of English language teaching in India, considering factors such as policy, curriculum, teaching methodologies, and technology integration. The review identifies the significant challenges learners and teachers face, including linguistic and cultural barriers, inadequate infrastructure, and limited teacher training. The study also highlights the opportunities and potential solutions to overcome these challenges, such as utilizing innovative teaching strategies and digital technologies. Based on the findings, the study suggests a way forward for developing English language teaching in India, emphasizing the need for comprehensive language policies, teacher development programs, and a learner-centered approac