Tolerância à deficiência de P: divergência genética em famílias da população-base CNA9.

O objetivo deste estudo foi o de caracterizar geneticamente 137 famílias S0:2 da população-base CNA9|3|1, sintetizada visando principalmente tolerância à deficiência hídrica e de P no solo.Apresentação oral - graduação

Acúmulo de prolina na laranjeira Pera sobre três porta-enxertos e sua interrelação com as doses de N no solo.

As folhas das laranjeiras apresentam altos teores de prolina, aminoácido reconhecido como marcador bioquímico de tolerância à seca. Com o objetivo de estudar as relações entre dose de nitrogênio (N) no solo e tolerância à seca da laranjeira ?Pera?, quando enxertada nos porta-enxertos ?Cravo?, ?Sunki Tropical? e ?San Diego?, foram estabelecidos três experimentos simultâneos no polo citrícola da Bahia e Sergipe no delineamento de blocos ao acaso, com quatro doses de N no solo e cinco repetições. Nas folhas, foram determinados o teor relativo de água, de prolina e de clorofila, nas estações úmida e seca, de nitrogênio, anualmente, além das taxas fotossintéticas. Durante quatro safras consecutivas, registrou-se a produtividade dos pomares. Para a maioria dos anos e porta-enxertos, os teores de N e de prolina nas folhas aumentaram em função da dose de N no solo, em contraste com o teor de clorofila e as taxas fotossintéticas. A produtividade foi modificada pela dose de N apenas na quarta safra, exceto para plantas sobre ?San Diego?. Os resultados indicaram que sob precipitação regular e frequente, os três porta-enxertos induzem, às folhas da laranjeira ?Pera?, aumentos crescentes no acúmulo de prolina em função das doses de N, mas sob chuvas escassas, o padrão de acúmulo de prolina foi alterado, o que variou com o porta-enxerto. A maior eficiência no uso da água e padrão de acúmulo de prolina proporcionado pelo porta-enxerto ?Sunki Tropical? sugerem sua alta tolerância à seca

HPLC-DAD analysis, antinociceptive and anti-inflammatory properties of the ethanolic extract of Hyptis umbrosa in mice

Hyptis umbrosa (syn. Mesosphaerum sidifolium) (Lamiaceae Family) has been used to treat several conditions such as gastrointestinal disorders, skin infections, nasal congestion, fever and cramps. The objective of this study was to evaluate the chemical composition, analgesic and anti-inflammatory profiles of ethanol extract from leaves of Hyptis umbrosa (EEB). HPLC-DAD was used to determine the fingerprint chromatogram of the extract. Male Swiss mice were orally pretreated with EEB (100, 200 or 400 mg/kg; 60 min before initiating algesic stimulation) and antinociceptive activity was assessed using the acetic acid-induced writhing model, formalin test and hyperalgesia induced by glutamate or capsaicin. Also, peritonitis was induced by the intrathoracic injection of carrageenan to quantify the total number of leukocytes. The presence of phenolic compounds in the extract was confirmed using HPLC-DAD. The treatment with EEB, at all doses, produced a significant analgesic effect against acetic acid-induced antinociceptive activity. In the formalin test, only the 400-mg/kg-dose of EEB had a significant effect in the first phase. However, all doses tested were able to reverse nociception in the second phase. The effect of all doses of EEB also showed a significant antinociceptive effect in the glutamate and capsaicin tests and inhibited the carrageenan-induced leukocyte migration to the peritoneal cavity. The present study suggests that the EEB possesses peripheral analgesic action and showed potential in reducing the spreading of the inflammatory processes. Also, it seems to be related with vanilloid and glutamate receptors

Estudo da reação de condensação entre 2-hidróxi-acetofenona e p-anisaldeído em meio básico.

A busca de substâncias com atividades biológicas tem grande interesse devido a resistência bacteriana frente ao arsenal terapêutico existente. Os flavonóides podem ser uma boa alternativa, pelo fato de serem oriundos de fontes vegetais. Neste trabalho relata-se o estudo da reação da 2-hidróxi- acetofenona com p-anisaldeído, na tentativa de obter a 2-hidróxi-chalcona, um intermediário chave na síntese de flavonóides. Neste estudo analisou-se os produtos formados pela variação das condições de reação, sob refluxo à 90ºC, durante 3 horas e 10% de solução de NaOH; à temperatura ambiente, sob agitação e sem aquecimento e 10 % de NaOH; e durante 3 horas de agitação magnética utilizando solução à 50% de NaOH. A mistura reacional foi analisada por HPLC, Espectrometria de massas e RMN de Hidrogênio

Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography

Background Exercise echocardiography (EE) is an established method to diagnose coronary artery disease (CAD). Chronotropic incompetence (CI) during the EE may be a marker of myocardial ischemia. The purpose of this investigation was to evaluate the additive value of CI during EE in CAD diagnosis. Methods Between 2000 and 2006, 4042 patients (1900 men with a mean age of 56 ± 11 years) were evaluated by EE. Based on the heart rate (HR) reached during the exercise test, the subjects were divided into two groups: G1 group – 490 patients who failed to achieve 85% of the maximal age-predicted HR, and G2 group – 3552 patients who were able to achieve 85% of the maximal age-predicted HR. Clinical characteristics, left ventricular wall motion abnormalities – wall motion score index (WMSI) – and coronary angiography (CA) were the parameters compared between the two groups. Results The left ventricular wall motion abnormalities were more frequent in G1 group than in G2 group (54% versus 26%; P < 0.00001). WMSI was higher in G1 group than in G2 group, both at rest (1.06 ± 0.17 versus 1.02 ± 0.09; P < 0.0001) and after exercise (1.12 ± 0.23 versus 1.04 ± 0.21; P < 0.0001). In G1 group, 82% of the patients with positive EE for myocardial ischemia presented obstructive coronary, compared to 71% (P = 0.03) in G2 group. Conclusion CI is associated with a higher frequency of myocardial ischemia during EE, reinforcing the concept that CI is a marker of the severity of myocardial ischemia

Measurement of the production of a W boson in association with a charm quark in pp collisions at √s = 7 TeV with the ATLAS detector

The production of a W boson in association with a single charm quark is studied using 4.6 fb−1 of pp collision data at s√ = 7 TeV collected with the ATLAS detector at the Large Hadron Collider. In events in which a W boson decays to an electron or muon, the charm quark is tagged either by its semileptonic decay to a muon or by the presence of a charmed meson. The integrated and differential cross sections as a function of the pseudorapidity of the lepton from the W-boson decay are measured. Results are compared to the predictions of next-to-leading-order QCD calculations obtained from various parton distribution function parameterisations. The ratio of the strange-to-down sea-quark distributions is determined to be 0.96+0.26−0.30 at Q 2 = 1.9 GeV2, which supports the hypothesis of an SU(3)-symmetric composition of the light-quark sea. Additionally, the cross-section ratio σ(W + +c¯¯)/σ(W − + c) is compared to the predictions obtained using parton distribution function parameterisations with different assumptions about the s−s¯¯¯ quark asymmetry

Measurements of fiducial and differential cross sections for Higgs boson production in the diphoton decay channel at s√=8 TeV with ATLAS

Measurements of fiducial and differential cross sections are presented for Higgs boson production in proton-proton collisions at a centre-of-mass energy of s√=8 TeV. The analysis is performed in the H → γγ decay channel using 20.3 fb−1 of data recorded by the ATLAS experiment at the CERN Large Hadron Collider. The signal is extracted using a fit to the diphoton invariant mass spectrum assuming that the width of the resonance is much smaller than the experimental resolution. The signal yields are corrected for the effects of detector inefficiency and resolution. The pp → H → γγ fiducial cross section is measured to be 43.2 ±9.4(stat.) − 2.9 + 3.2 (syst.) ±1.2(lumi)fb for a Higgs boson of mass 125.4GeV decaying to two isolated photons that have transverse momentum greater than 35% and 25% of the diphoton invariant mass and each with absolute pseudorapidity less than 2.37. Four additional fiducial cross sections and two cross-section limits are presented in phase space regions that test the theoretical modelling of different Higgs boson production mechanisms, or are sensitive to physics beyond the Standard Model. Differential cross sections are also presented, as a function of variables related to the diphoton kinematics and the jet activity produced in the Higgs boson events. The observed spectra are statistically limited but broadly in line with the theoretical expectations

Search for dark matter in events with heavy quarks and missing transverse momentum in pp collisions with the ATLAS detector

This article reports on a search for dark matterpair production in association with bottom or top quarks in20.3fb−1ofppcollisions collected at√s=8TeVbytheATLAS detector at the LHC. Events with large missing trans-verse momentum are selected when produced in associationwith high-momentum jets of which one or more are identifiedas jets containingb-quarks. Final states with top quarks areselected by requiring a high jet multiplicity and in some casesa single lepton. The data are found to be consistent with theStandard Model expectations and limits are set on the massscale of effective field theories that describe scalar and tensorinteractions between dark matter and Standard Model par-ticles. Limits on the dark-matter–nucleon cross-section forspin-independent and spin-dependent interactions are alsoprovided. These limits are particularly strong for low-massdark matter. Using a simplified model, constraints are set onthe mass of dark matter and of a coloured mediator suitableto explain a possible signal of annihilating dark matter