Global Models, The Biospheric Approach (Theory of the Noosphere)

The problem of the coevolution of mankind and the biosphere, i.e., the relationship between the process of the evolution of the biosphere and the evolution of human activity which provides a homeostasis for human civilization, has become one of the principal problems of human ecology. The first step in an extensive program of interdisciplinary research is the creation of a system of mathematical models which would serve as a framework for planning international research programs. The research described herein has two stages. The first stage, a still primitive system of models was constructed and analyzed, using systems dynamics techniques. This system of models, outlined in the second section of the paper, has already helped the authors in their contacts with experts in biology, soil science, etc., and the creation of an information base has in essence, turned into a discussion of plans for future work. Studies connected with simulating the evolution of the biosphere were developed in three directions: simulation of processes of a biotic nature, simulation of climate, and simulation of human activity. Experimental results obtained using this system in the "if...then" mode, may be helpful for understanding, at least on a qualitative basis, possible impacts of human activity on the evolution of the biosphere assuming that the present day trends remain unchanged. This system of models is at present programmed at IIASA and is ready to be used for simulation experiments. The second step in the research is based on an understanding of the fact that the systems dynamic approach is not sufficient for the elaboration and study of the system of models which describes human activity. Furthermore, it is necessary to analyze and coordinate models developed by experts in varied branches of science -- biologists, climatologists, economists, etc. Thus, it is necessary to elaborate new mathematical techniques that can be used in the investigation of global coevolution problems. Some principles for the development of these techniques were formulated at the Computing Center of the USSR Academy of Sciences and are presented herein. The three main principles are: (1) Linear parametrization of comprehensive submodels; (2) Models of human activity are split into two levels -- the decision-making level and the technological level -- and a description of the system of models at the technological level only; (3) Analysis and coordination of the system of models by constructing a set of all reachable values of performance indices (The Generalized Reachable Sets Approach). The linear parametrization procedure for a climate model which is essentially the Mintz-Arakawa global atmospheric circulation model as described by Gates et al. (1971) and modified to account for the climatic trends due to the influence of anthropogenic factors, is described in the third section of the paper. The problems of modeling human activity and the main features of the Generalized Reachable Sets approach, as well as the general scheme of analysis of global biospheric models, are presented in the fourth section of the paper. This work, which is now in the early stages, calls for a great deal of scientific effort over a long period of time. The authors anticipate that the importance of the research in this direction will be internationally recognized and supported

Renormalization of the P- and T-odd nuclear potentials by the strong interaction and enhancement of P-odd effective field

Approximate analytical formulas for the self-consistent renormalization of P,T-odd and P-odd weak nuclear potentials by the residual nucleon-nucleon strong interaction are derived. The contact spin-flip nucleon-nucleon interaction reduces the constant of the P,T-odd potential 1.5 times for the proton and 1.8 times for the neutron. Renormalization of the P-odd potential is caused by the velocity dependent spin-flip component of the strong interaction. In the standard variant of $\pi + \rho$-exchange, the conventional strength values lead to anomalous enhancement of the P-odd potential. Moreover, the $\pi$-meson exchange contribution seems to be large enough to generate an instability (pole) in the nuclear response to a weak potential.Comment: 5 pages, Revtex3, no figure

Structure of Low-Energy Collective 0−0^{-}-States in Doubly Magic Nuclei and Matrix Elements of the P-odd and P- and T-odd Weak Interaction

The structure of the collective low-energy $J^{\pi}=0^{-}$ (T=0 and T=1) modes is studied for a doubly magic nucleus in a schematic analytic model of RPA. The $0^{-}$ phonon states ($T= 0,1$) lie at energies E_{T=0}(0^{-}) \alt \omega and $E_{T=1}(0^{-}) > \omega$, where $\omega$ is the oscillator frequency. The matrix elements of P-odd and P- and T-odd weak one-body potentials connecting the ground state to these $0^{-}$-states, $W_{coll}$, are enhanced by the factor $\sim 2 (\frac{\omega}{E})^{1/2}A^{1/3} \sim 10$ as compared to the single-particle value $w_{sp}$ what can result in values $|W_{coll}| \sim 20-30 eV$ if standard values of DDH parameters are used for $w_{sp}$. Similar enhancement arises in the P- and T-odd case.Comment: 15 pages, REVTEX 3, 2 figure

Современные аспекты использования клеточных технологий в гинекологии

The article presents a review of publications devoted to the use of regenerative technologies in the treatment of gynecological pathologies. The authors describe possible ways to solve these problems by analyzing the experimental studies conducted in the world. Identified the main indications for tissue engineering: Ashermans syndrome, primary ovarian failure, infertility caused by chemotherapy, a niche in the uterus, endometrial pathology (endometriosis, endometrial problems, etc.), cervical pathology, female genital tract abnormalities, pelvic organ prolapse. The results of clinical trials of cell therapy aimed at treating infertility caused by Asherman syndrome and primary ovarian failure, female genital tract abnormalities, as well as such rare pathology as a niche of the uterus. At the preclinical stage, in addition to the above, considered cellular therapy of cervical pathologies, endometrial diseases and pelvic organ prolapse. Eximined cell cultures and the level of their influence on the regeneration of the female reproductive system structures, presented the biological scaffolds that stimulate the growth of stem cells, their effectiveness and shortcomings are covered.В предлагаемом систематическом обзоре представлен анализ данных клинических и доклинических исследований в области гинекологии, в которых применяли клеточные технологии. Определены основные показания для применения тканеинженерных конструкций: синдром Ашермана, первичная яичниковая недостаточность, бесплодие, несостоятельность рубца на матке, патологии эндометрия (эндометриоз, проблемы эндометрия и др.), патологии шейки матки, аномалии развития женской половой сферы, пролапс тазовых органов. На данный момент описаны результаты клинических испытаний клеточной терапии, направленной на лечение бесплодия при синдроме Ашермана и первичной яичниковой недостаточности, врожденных аномалиях женской половой сферы, а также при такой редкой патологии, как несостоятельность рубца на матке. На доклинической стадии помимо вышеперечисленных рассматривается клеточная терапия патологий шейки матки, заболеваний эндометрия и пролапса тазовых органов. Представлены клеточные культуры и уровень их воздействия на процессы регенерации структур половой системы женщины, рассмотрены биологические матрицы, стимулирующие рост стволовых клеток, их эффективность и недостатки. В настоящее время в России появилась нормативно-правовая база для внедрения в клиническую практику новых средств лечения с использованием живых клеток человека

Experimental Evidence of Giant Electron - Gamma Bursts Generated by Extensive Atmospheric Showers in Thunderclouds

The existence of a new phenomena - giant electron-gamma bursts is established. The bursts are generated in thunderclouds as a result of the combined action of runaway breakdown and extensive atmosphere showers (RB-EAS). The experiments were fulfilled at the Tien Shan Mountain Scientific Station using EAS-Radio installation. This specially constructed installation consists of a wide spread EAS trigger array and a high time resolution radiointerferometer.Comment: 30 pages, 16 figure

Search for displaced vertices arising from decays of new heavy particles in 7 TeV pp collisions at ATLAS

We present the results of a search for new, heavy particles that decay at a significant distance from their production point into a final state containing charged hadrons in association with a high-momentum muon. The search is conducted in a pp-collision data sample with a center-of-mass energy of 7 TeV and an integrated luminosity of 33 pb^-1 collected in 2010 by the ATLAS detector operating at the Large Hadron Collider. Production of such particles is expected in various scenarios of physics beyond the standard model. We observe no signal and place limits on the production cross-section of supersymmetric particles in an R-parity-violating scenario as a function of the neutralino lifetime. Limits are presented for different squark and neutralino masses, enabling extension of the limits to a variety of other models.Comment: 8 pages plus author list (20 pages total), 8 figures, 1 table, final version to appear in Physics Letters

Measurement of the polarisation of W bosons produced with large transverse momentum in pp collisions at sqrt(s) = 7 TeV with the ATLAS experiment

This paper describes an analysis of the angular distribution of W->enu and W->munu decays, using data from pp collisions at sqrt(s) = 7 TeV recorded with the ATLAS detector at the LHC in 2010, corresponding to an integrated luminosity of about 35 pb^-1. Using the decay lepton transverse momentum and the missing transverse energy, the W decay angular distribution projected onto the transverse plane is obtained and analysed in terms of helicity fractions f0, fL and fR over two ranges of W transverse momentum (ptw): 35 < ptw < 50 GeV and ptw > 50 GeV. Good agreement is found with theoretical predictions. For ptw > 50 GeV, the values of f0 and fL-fR, averaged over charge and lepton flavour, are measured to be : f0 = 0.127 +/- 0.030 +/- 0.108 and fL-fR = 0.252 +/- 0.017 +/- 0.030, where the first uncertainties are statistical, and the second include all systematic effects.Comment: 19 pages plus author list (34 pages total), 9 figures, 11 tables, revised author list, matches European Journal of Physics C versio

Observation of a new chi_b state in radiative transitions to Upsilon(1S) and Upsilon(2S) at ATLAS

The chi_b(nP) quarkonium states are produced in proton-proton collisions at the Large Hadron Collider (LHC) at sqrt(s) = 7 TeV and recorded by the ATLAS detector. Using a data sample corresponding to an integrated luminosity of 4.4 fb^-1, these states are reconstructed through their radiative decays to Upsilon(1S,2S) with Upsilon->mu+mu-. In addition to the mass peaks corresponding to the decay modes chi_b(1P,2P)->Upsilon(1S)gamma, a new structure centered at a mass of 10.530+/-0.005 (stat.)+/-0.009 (syst.) GeV is also observed, in both the Upsilon(1S)gamma and Upsilon(2S)gamma decay modes. This is interpreted as the chi_b(3P) system.Comment: 5 pages plus author list (18 pages total), 2 figures, 1 table, corrected author list, matches final version in Physical Review Letter

Measurement of the inclusive isolated prompt photon cross-section in pp collisions at sqrt(s)= 7 TeV using 35 pb-1 of ATLAS data

A measurement of the differential cross-section for the inclusive production of isolated prompt photons in pp collisions at a center-of-mass energy sqrt(s) = 7 TeV is presented. The measurement covers the pseudorapidity ranges |eta|<1.37 and 1.52<=|eta|<2.37 in the transverse energy range 45<=E_T<400GeV. The results are based on an integrated luminosity of 35 pb-1, collected with the ATLAS detector at the LHC. The yields of the signal photons are measured using a data-driven technique, based on the observed distribution of the hadronic energy in a narrow cone around the photon candidate and the photon selection criteria. The results are compared with next-to-leading order perturbative QCD calculations and found to be in good agreement over four orders of magnitude in cross-section.Comment: 7 pages plus author list (18 pages total), 2 figures, 4 tables, final version published in Physics Letters

Reducing heterotic M-theory to five dimensional supergravity on a manifold with boundary

This paper constructs the reduction of heterotic $M$-theory in eleven dimensions to a supergravity model on a manifold with boundary in five dimensions using a Calabi-Yau three-fold. New results are presented for the boundary terms in the action and for the boundary conditions on the bulk fields. Some general features of dualisation on a manifold with boundary are used to explain the origin of some topological terms in the action. The effect of gaugino condensation on the fermion boundary conditions leads to a `twist' in the chirality of the gravitino which can provide an uplifting mechanism in the vacuum energy to cancel the cosmological constant after moduli stabilisation.Comment: 16 pages, RevTe