Lattice regularized chiral perturbation theory

Chiral perturbation theory can be defined and regularized on a spacetime lattice. A few motivations are discussed here, and an explicit lattice Lagrangian is reviewed. A particular aspect of the connection between lattice chiral perturbation theory and lattice QCD is explored through a study of the Wess-Zumino-Witten term.Comment: 7 pages, 1 figure, presented at the Workshop on Lattice Hadron Physics (LHP2003), Cairns, Australi

A method to assess assembly complexity of industrial products in early design phase

Complexity is one of the factors, inducing high cost, operational issues, and increased lead time for product realization and continues to pose challenges to manufacturing systems. One solution to reduce the negative impacts of complexity is its assessment, which can help designers to compare and rationalize various designs that meet the functional requirements. In this paper, a systemic approach is proposed to assess complexity of a product's assembly. The approach is based on Hückel's molecular orbital theory and defines complexity as a combination of both the complexity of product entities and their topological connections. In this model, the complexity of product entities (i.e., components and liaisons) is defined as the degree to which the entity comprises structural characteristics that lead to challenges during handling or fitting operations. The characterization of entity complexities is carried out based on the widely used DFA principles. Moreover, the proposed approach is tested on two case studies from electronics industry for its validity. The results showed that the approach can be used at initial design stages to improve both the quality and assemblability of products by reducing their complexity and accompanying risks

Hydrogen fuel cell pick and place assembly systems : heuristic evaluation of reconfigurability and suitability

Proton Exchange Membrane Fuel Cells (PEMFCs) offer numerous advantages over combustion technology but they remain economically uncompetitive except for in niche applications. A portion of this cost is attributed to a lack of assembly expertise and the associated risks. To solve this problem, this research investigates the assembly systems that do exist for this product and systematically decomposes them into their constituent components to evaluate reconfigurability and suitability to product. A novel method and set of criteria are used for evaluation taking inspiration from heuristic approaches for evaluating manufacturing system complexity. It is proposed that this can be used as a support tool at the design stage to meet the needs of the product while having the capability to accept potential design changes and variants for products beyond the case study presented in this work. It is hoped this work develops a new means to support in the design of reconfigurable systems and form the foundation for fuel cell assembly best practice, allowing this technology to reduce in cost and find its way into a commercial space

Economic liberalization and the antecedents of top management teams: evidence from Turkish 'big' business

There has been an increased interest in the last two decades in top management teams (TMTs) of business firms. Much of the research, however, has been US-based and concerned primarily with TMT effects on organizational outcomes. The present study aims to expand this literature by examining the antecedents of top team composition in the context of macro-level economic change in a late-industrializing country. The post-1980 trade and market reforms in Turkey provided the empirical setting. Drawing upon the literatures on TMT and chief executive characteristics together with punctuated equilibrium models of change and institutional theory, the article develops the argument that which firm-level factors affect which attributes of TMT formations varies across the early and late stages of economic liberalization. Results of the empirical investigation of 71 of the largest industrial firms in Turkey broadly supported the hypotheses derived from this premise. In the early stages of economic liberalization the average age and average organizational tenure of TMTs were related to the export orientation of firms, whereas in later stages, firm performance became a major predictor of these team attributes. Educational background characteristics of teams appeared to be under stronger institutional pressures, altering in different ways in the face of macro-level change

A framework for automatically realizing assembly sequence changes in a virtual manufacturing environment

Global market pressures and the rapid evolution of technologies and materials force manufacturers to constantly design, develop and produce new and varied products to maintain a competitive edge. Although virtual design and engineering tools have been key to supporting this fast rate of change, there remains a lack of seamless integration between and within tools across the domains of product, process, and resource design - especially to accommodate change. This research examines how changes to designs within these three domains can be captured and evaluated within a component based engineering tool (vueOne, developed by the Automation Systems Group at the University of Warwick). This paper describes how and where data within these tools can be mapped to quickly evaluate change (where typically a tedious process of data entry is required) decreasing lead times and cost and increasing productivity. The approach is tested on a sub-assembly of a hydrogen fuel cell, where an assembly system is modelled and changes are made to the sequence which is translated through to control logic. Although full implementation has not yet been realized, the concept has the potential to radically change the way changes are made and the approach can be extended to supporting other change types provided the appropriate rules and mapping

Comparison of damage sensitivities of autoregressive coefficients and natural frequencies for structural health monitoring of a top tensioned riser

Peer reviewedPublisher PD

Skeletal muscle-on-a-chip in microgravity as a platform for regeneration modeling and drug screening

Microgravity has been shown to lead to both muscle atrophy and impaired muscle regeneration. The purpose was to study the efficacy of microgravity to model impaired muscle regeneration in an engineered muscle platform and then to demonstrate the feasibility of performing drug screening in this model. Engineered human muscle was launched to the International Space Station National Laboratory, where the effect of microgravity exposure for 7 days was examined by transcriptomics and proteomics approaches. Gene set enrichment analysis of engineered muscle cultured in microgravity, compared to normal gravity conditions, highlighted a metabolic shift toward lipid and fatty acid metabolism, along with increased apoptotic gene expression. The addition of pro-regenerative drugs, insulin-like growth factor-1 (IGF-1) and a 15-hydroxyprostaglandin dehydrogenase inhibitor (15-PGDH-i), partially inhibited the effects of microgravity. In summary, microgravity mimics aspects of impaired myogenesis, and the addition of these drugs could partially inhibit the effects induced by microgravity

Tree Shaped in Channels Parallel and Counter Flow Through Heat Exchanger Heat Transfer and Flow Investigation of Characteristic

I n this study, a heat exchanger system capable of working on tree-shaped three-level parallel and counter flow basis was designed and manufactured based on the branched Fractal like flow channel structure. A similar phylum of heat exchanger on discs onto one surface of the lower and upper plates and both surfaces of middle plate, 156 Branched-micro channels with cylindrical sections were opened in three levels symmetrically with each other at different levels and diameters. According to the parallel and counter flow type based open circuit and closed circuit principle, the fluid enters the system at equal thermal capacity ratios from the axial or radial connection points and discharges. In the open circuit operating conditions, the heating water is in the temperature range of 35-45°C and the flow rate is 2,0-4,0 lt / min. Similarly, in the closed circuit operating conditions, the heating water is in temperature range of 45-60°C and the flow rate is 2,0-4,0 lt/ min. During the experimental work, the temperature and hydrodynamic characteristics of the system are controlled through software written in the MATLAB R2013b package program. Experimental and numerical analyzes were carried out using ANSYS-Fluent ready packet programs. In the analysis, in the increasing flow rate, positions of some external and lateral channels are determined as cause of the decreasing in level of velocity. The result, requirement of designation as the bifurcation geometry divides the mass flow rate equally for each level of branching, is obtained. The results show that increase in level of branches is not important on the fluid channels which includes this kind fractal branch channel with tree-shaped. The results also show that, in the branched model heat exchanger, for opened and closed circuits, parallel flow increasing branching levels, heating unit and cooling unit is more efficient than the counter flow increasing branching levels heating unit and decreasing branching level cooling unit conditions

Impacts of the Tropical Pacific/Indian Oceans on the Seasonal Cycle of the West African Monsoon

The current consensus is that drought has developed in the Sahel during the second half of the twentieth century as a result of remote effects of oceanic anomalies amplified by local land–atmosphere interactions. This paper focuses on the impacts of oceanic anomalies upon West African climate and specifically aims to identify those from SST anomalies in the Pacific/Indian Oceans during spring and summer seasons, when they were significant. Idealized sensitivity experiments are performed with four atmospheric general circulation models (AGCMs). The prescribed SST patterns used in the AGCMs are based on the leading mode of covariability between SST anomalies over the Pacific/Indian Oceans and summer rainfall over West Africa. The results show that such oceanic anomalies in the Pacific/Indian Ocean lead to a northward shift of an anomalous dry belt from the Gulf of Guinea to the Sahel as the season advances. In the Sahel, the magnitude of rainfall anomalies is comparable to that obtained by other authors using SST anomalies confined to the proximity of the Atlantic Ocean. The mechanism connecting the Pacific/Indian SST anomalies with West African rainfall has a strong seasonal cycle. In spring (May and June), anomalous subsidence develops over both the Maritime Continent and the equatorial Atlantic in response to the enhanced equatorial heating. Precipitation increases over continental West Africa in association with stronger zonal convergence of moisture. In addition, precipitation decreases over the Gulf of Guinea. During the monsoon peak (July and August), the SST anomalies move westward over the equatorial Pacific and the two regions where subsidence occurred earlier in the seasons merge over West Africa. The monsoon weakens and rainfall decreases over the Sahel, especially in August.Peer reviewe

Severe early onset preeclampsia: short and long term clinical, psychosocial and biochemical aspects

Preeclampsia is a pregnancy specific disorder commonly defined as de novo hypertension and proteinuria after 20 weeks gestational age. It occurs in approximately 3-5% of pregnancies and it is still a major cause of both foetal and maternal morbidity and mortality worldwide1. As extensive research has not yet elucidated the aetiology of preeclampsia, there are no rational preventive or therapeutic interventions available. The only rational treatment is delivery, which benefits the mother but is not in the interest of the foetus, if remote from term. Early onset preeclampsia (<32 weeks’ gestational age) occurs in less than 1% of pregnancies. It is, however often associated with maternal morbidity as the risk of progression to severe maternal disease is inversely related with gestational age at onset2. Resulting prematurity is therefore the main cause of neonatal mortality and morbidity in patients with severe preeclampsia3. Although the discussion is ongoing, perinatal survival is suggested to be increased in patients with preterm preeclampsia by expectant, non-interventional management. This temporising treatment option to lengthen pregnancy includes the use of antihypertensive medication to control hypertension, magnesium sulphate to prevent eclampsia and corticosteroids to enhance foetal lung maturity4. With optimal maternal haemodynamic status and reassuring foetal condition this results on average in an extension of 2 weeks. Prolongation of these pregnancies is a great challenge for clinicians to balance between potential maternal risks on one the eve hand and possible foetal benefits on the other. Clinical controversies regarding prolongation of preterm preeclamptic pregnancies still exist – also taking into account that preeclampsia is the leading cause of maternal mortality in the Netherlands5 - a debate which is even more pronounced in very preterm pregnancies with questionable foetal viability6-9. Do maternal risks of prolongation of these very early pregnancies outweigh the chances of neonatal survival? Counselling of women with very early onset preeclampsia not only comprises of knowledge of the outcome of those particular pregnancies, but also knowledge of outcomes of future pregnancies of these women is of major clinical importance. This thesis opens with a review of the literature on identifiable risk factors of preeclampsia