3,185 research outputs found

    A Hierachical Evolutionary Algorithm for Multiobjective Optimization in IMRT

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    Purpose: Current inverse planning methods for IMRT are limited because they are not designed to explore the trade-offs between the competing objectives between the tumor and normal tissues. Our goal was to develop an efficient multiobjective optimization algorithm that was flexible enough to handle any form of objective function and that resulted in a set of Pareto optimal plans. Methods: We developed a hierarchical evolutionary multiobjective algorithm designed to quickly generate a diverse Pareto optimal set of IMRT plans that meet all clinical constraints and reflect the trade-offs in the plans. The top level of the hierarchical algorithm is a multiobjective evolutionary algorithm (MOEA). The genes of the individuals generated in the MOEA are the parameters that define the penalty function minimized during an accelerated deterministic IMRT optimization that represents the bottom level of the hierarchy. The MOEA incorporates clinical criteria to restrict the search space through protocol objectives and then uses Pareto optimality among the fitness objectives to select individuals. Results: Acceleration techniques implemented on both levels of the hierarchical algorithm resulted in short, practical runtimes for optimizations. The MOEA improvements were evaluated for example prostate cases with one target and two OARs. The modified MOEA dominated 11.3% of plans using a standard genetic algorithm package. By implementing domination advantage and protocol objectives, small diverse populations of clinically acceptable plans that were only dominated 0.2% by the Pareto front could be generated in a fraction of an hour. Conclusions: Our MOEA produces a diverse Pareto optimal set of plans that meet all dosimetric protocol criteria in a feasible amount of time. It optimizes not only beamlet intensities but also objective function parameters on a patient-specific basis

    An application of multiobjetive programming to the study of workers' satisfaction in the spanish labour market

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    In this paper, a multiobjective scheme is used to study the satisfaction levels of the Spanish workers. Data obtained from a panel survey conducted in several European countries are used to build up a multiobjective model, on the basis of a previous statistical and econometric analysis of these data. Then, a Reference Point based method is implemented to determine the profile of the most satisfied worker in Spain nowadays. Finally, a combined Goal Programming – Reference Point approach is used to determine policies than can be carried out in order to increase the workers’ satisfaction levels.Workers’ Satisfaction, Econometric analyses, Multiobjective Programming.

    Metaheuristic design of feedforward neural networks: a review of two decades of research

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    Over the past two decades, the feedforward neural network (FNN) optimization has been a key interest among the researchers and practitioners of multiple disciplines. The FNN optimization is often viewed from the various perspectives: the optimization of weights, network architecture, activation nodes, learning parameters, learning environment, etc. Researchers adopted such different viewpoints mainly to improve the FNN's generalization ability. The gradient-descent algorithm such as backpropagation has been widely applied to optimize the FNNs. Its success is evident from the FNN's application to numerous real-world problems. However, due to the limitations of the gradient-based optimization methods, the metaheuristic algorithms including the evolutionary algorithms, swarm intelligence, etc., are still being widely explored by the researchers aiming to obtain generalized FNN for a given problem. This article attempts to summarize a broad spectrum of FNN optimization methodologies including conventional and metaheuristic approaches. This article also tries to connect various research directions emerged out of the FNN optimization practices, such as evolving neural network (NN), cooperative coevolution NN, complex-valued NN, deep learning, extreme learning machine, quantum NN, etc. Additionally, it provides interesting research challenges for future research to cope-up with the present information processing era

    A Methodological Guide to Multiobjective Optimization

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    During the last few years, multiobjective optimization has received growing attention: the number of publications related to this subject between 1974 and 1979 exceeds 120. There are many approaches, techniques and tools related to multiobjective decision-making and optimization; however, not all approaches are equally developed, and the resulting tools are often applied because of certain traditions rather than their suitability for solving a given problem. Therefore, this paper is devoted to a comparative evaluation of various approaches and tools. This evaluation is based, however, first on a classification of problems of multiobjective decision making and optimization. Thereafter, the available approaches, methods, techniques and tools are shortly presented and evaluated in terms of suitability for various classes of problems. The final part of the paper presents a broader description of a relatively new approach based on reference objective levels, not fully developed yet but applicable in many classes of problems. A new notion of extended threshold utility functions, other basic theoretical results, applicational examples and directions of further research related to this approach are presented

    IAC-DIDAS-N: A Dynamic Interactive Decision Analysis and Support System for Multicriteria Analysis of Nonlinear Models with Nonlinear Model Generator Supporting Model Analysis

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    This paper is one of the series of 11 Working Papers presenting the software for interactive decision support and software tools for developing decision support systems. These products constitute the outcome of the contracted study agreement between the System and Decision Sciences Program at IIASA and several Polish scientific institutions. The theoretical part of these results is presented in the IIASA Working Paper WP-88-071 entitled "Theory, Software and Testing Examples in Decision Support Systems". This volume contains the theoretical and methodological backgrounds of the software systems developed within the project. This paper presents the user documentation for decision analysis and support systems of DIDAS family designed for supporting decision problems when the model of the system under study can be formulated in terms of set of nonlinear equations. The program presented in the paper, called IAC-DIDAS-N is provided with a nonlinear model generator and editor that support definition, edition and symbolic differentiation of nonlinear models for multiobjective decision analysis. A specially introduced standard of defining nonlinear programming models for multiobjective optimization helps to connect the model generator with other parts of the system. Optimization runs involved in interactive, multiobjective decision analysis are performed by a new version of nonlinear programming algorithm specially adapted for multiobjective problems. This algorithm is based on shifted penalty functions and projected conjugate directions techniques. An attachment to this paper presents user documentation for a pilot version of a nonlinear model generator with facilities for symbolic differentiation and other means of fundamental model analysis
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